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The pyrin domain of IFI16 forms a distinct filament structure important for IFI16-mediated enhancement of STING activation

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1. scibot 20 Feb 2026
  
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  plasmid_74099
  
  DOI: 10.1016/j.str.2026.01.011
  
  Resource: RRID:Addgene_74099
  
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sciencedirect.com/science/article/pii/S0969212626000134
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Visualizing insecticide control of insect TRP channel function and assembly

1
1. scibot 22 Jan 2026
  
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  RRID:Addgene_74099
  
  DOI: 10.1038/s41467-025-67287-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12808645/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Structural basis for ligand promiscuity and high signaling activity of Kaposi’s Sarcoma-associated Herpesvirus-encoded GPCR

1
1. scibot 23 Nov 2025
  
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  74099
  
  DOI: 10.1038/s41467-025-63457-4
  
  Resource: RRID:Addgene_74099
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12462484/
www.sciencedirect.com www.sciencedirect.com

Nanoscale conformational dynamics of human propionyl-CoA carboxylase

1
1. scibot 06 Nov 2025
  
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  Plasmid_74099
  
  DOI: 10.1016/j.str.2025.10.009
  
  Resource: RRID:Addgene_74099
  
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sciencedirect.com/science/article/pii/S096921262500396X
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Tuning insulin receptor signaling using de novo-designed agonists

1
1. scibot 15 Oct 2025
  
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  Addgene, Cat#74099
  
  DOI: 10.1016/j.molcel.2025.09.020
  
  Resource: RRID:Addgene_74099
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1097276525007804
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Structural and functional significance of Aedes aegypti AgBR1 flavivirus immunomodulator

1
1. scibot 15 Jun 2025
  
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  pEZT-BM
  
  DOI: 10.1128/jvi.01878-24
  
  Resource: RRID:Addgene_74099
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_74099
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12090808/
elifesciences.org elifesciences.org

ATP-release pannexin channels are gated by lysophospholipids

1
1. scibot 11 Jun 2025
  
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  Addgene: 74099
  
  DOI: 10.7554/eLife.107067.1
  
  Resource: RRID:Addgene_74099
  
  Curator: @evieth
  
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elifesciences.org/reviewed-preprints/107067v1
May 2025
elifesciences.org elifesciences.org

Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1

1
1. scibot 29 May 2025
  
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  RRID:Addgene_74099
  
  DOI: 10.7554/eLife.105396
  
  Resource: RRID:Addgene_74099
  
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elifesciences.org/articles/105396
elifesciences.org elifesciences.org

ATP-release pannexin channels are gated by lysophospholipids

1
1. scibot 17 May 2025
  
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  Addgene: 74099
  
  DOI: 10.7554/eLife.107067
  
  Resource: RRID:Addgene_74099
  
  Curator: @dhovakimyan1
  
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  DOI:10.7554/eLife.107067 RRID:Addgene_74099
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DOI:10.7554/eLife.107067

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elifesciences.org/articles/107067
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling

1
1. scibot 04 Jan 2025
  
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  Addgene_74099
  
  DOI: 10.7554/eLife.96743
  
  Resource: RRID:Addgene_74099
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695057/
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2

1
1. scibot 05 May 2024
  
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  pEZT-BM
  
  DOI: 10.1038/s41467-024-48028-3
  
  Resource: RRID:Addgene_74099
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11059360/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel

1
1. scibot 30 Jun 2023
  
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  Plasmid_74099
  
  DOI: 10.1016/j.molcel.2023.06.004
  
  Resource: RRID:Addgene_74099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_74099
  
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  RRID:Addgene_74099
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sciencedirect.com/science/article/pii/S1097276523004264
Dec 2022
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Structure and gating mechanism of the α7 nicotinic acetylcholine receptor

1
1. scibot 03 Dec 2022
  
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  Addgene_74099
  
  DOI: 10.1016/j.cell.2021.02.049
  
  Resource: RRID:Addgene_74099
  
  Curator: @bandrow
  
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sciencedirect.com/science/article/pii/S0092867421002385
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4

1
1. scibot 18 Mar 2022
  
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  RRID:Addgene_74099
  
  DOI: 10.3389/fphar.2022.832931
  
  Resource: RRID:Addgene_74099
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8919721/
Feb 2022
www.sciencedirect.com www.sciencedirect.com

High-throughput identification of autoantibodies that target the human exoproteome

1
1. scibot 18 Feb 2022
  
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  RRID:Addgene_74099
  
  DOI: 10.1016/j.crmeth.2022.100172
  
  Resource: RRID:Addgene_74099
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2667237522000248
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Structural and compositional diversity in the kainate receptor family

1
1. scibot 28 Oct 2021
  
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  Plasmid_74099
  
  DOI: 10.1016/j.celrep.2021.109891
  
  Resource: RRID:Addgene_74099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_74099
  
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sciencedirect.com/science/article/pii/S2211124721013619
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Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel

1
1. scibot 26 Oct 2021
  
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  Plasmid_74099
  
  DOI: 10.1016/j.neuron.2021.10.006
  
  Resource: RRID:Addgene_74099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_74099
  
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  RRID:Addgene_74099
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sciencedirect.com/science/article/pii/S0896627321007741
May 2021
www.cell.com www.cell.com

Structural mechanisms of gating and selectivity of human rod CNGA1 channel

1
1. scibot 08 May 2021
  
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  Plasmid_74099
  
  DOI: 10.1016/j.neuron.2021.02.007
  
  Resource: RRID:Addgene_74099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_74099
  
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  RRID:Addgene_74099
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cell.com/neuron/fulltext/S0896-6273(21)00081-7
Jan 2020
elifesciences.org elifesciences.org

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

1
1. scibot 13 Jan 2020
  
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  plasmid_74099
  
  DOI: 10.7554/eLife.47650
  
  Resource: RRID:Addgene_74099
  
  Curator: @Naa003
  
  SciCrunch record: plasmid_74099
  
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  RRID:Addgene_74099 RRIDCUR:Validated
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RRID:Addgene_74099

RRIDCUR:Validated

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scibot

URL

elifesciences.org/articles/47650