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Lactate dehydrogenase A-dependent redox control of selective mRNA translation directs monocyte fate commitment

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1. scibot 17 Oct 2026
  
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  RRID:Addgene_75285
  
  DOI: 10.1016/j.immuni.2026.09.022
  
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sciencedirect.com/science/article/pii/S1074761326003973
Aug 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mitochondrial l-2-hydroxyglutarate is a physiological signalling metabolite

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1. scibot 09 Aug 2026
  
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  DOI: 10.1038/s41586-026-10564-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13391416/
Jul 2026
54.241.53.176 54.241.53.176

Complex I protein NDUFB9 is a metabolic vulnerability in triple negative breast cancer brain metastases

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1. scibot 07 Jul 2026
  
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  Addgene_75285
  
  DOI: 10.1038/s41467-026-72927-2
  
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54.241.53.176/fbba371e047a1863a9be5a679e9c16c3020d9509/s41467-026-72927-2_reference-html.html
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Aspartate availability drives differential engagement of the malate-aspartate shuttle

1
1. scibot 04 Mar 2026
  
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  Addgene_75285
  
  DOI: 10.1016/j.molcel.2026.02.004
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12952686/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD

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1. scibot 23 Nov 2025
  
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  DOI: 10.1038/s42255-025-01368-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12552132/
Sep 2025
www.nature.com www.nature.com

Redox-dependent liver gluconeogenesis impacts different intensity exercise in mice

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1. scibot 23 Sep 2025
  
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  RRID:Addgene_75285
  
  DOI: 10.1038/s42255-025-01373-z
  
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nature.com/articles/s42255-025-01373-z
Aug 2025
52.53.155.43 52.53.155.43

2025.08.10.669191v1.full-html.html

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1. scibot 20 Aug 2025
  
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  Plasmid_75285
  
  DOI: 10.1101/2025.08.10.669191
  
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52.53.155.43/f08dbae15affcc9e9ce4d40e9de902464b2a7113/2025.08.10.669191v1.full-html.html
Jul 2025
www.biorxiv.org www.biorxiv.org

Estrogens protect bone mass by inhibiting NAD+ metabolism in osteoclasts

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1. scibot 23 Jul 2025
  
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  RRID:Addgene_75285
  
  DOI: 10.1101/2025.07.11.664289
  
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biorxiv.org/content/10.1101/2025.07.11.664289v1
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lactate dehydrogenase A-coupled NAD+ regeneration is critical for acute myeloid leukemia cell survival

1
1. scibot 15 Jun 2025
  
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  75285
  
  DOI: 10.1186/s40170-025-00392-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12090514/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Respiratory complex I‐mediated NAD + regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21 Cip1 expression by SIRT3 and SIRT7

1
1. scibot 14 Jun 2025
  
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  plasmid_75285
  
  DOI: 10.1002/1878-0261.13808
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12161471/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lactate dehydrogenase A-coupled NAD+ regeneration is critical for acute myeloid leukemia cell survival

1
1. scibot 07 Apr 2025
  
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  DOI: 10.1101/2025.03.03.641255
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11908160/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Intrinsic electrical activity drives small-cell lung cancer progression

1
1. scibot 23 Mar 2025
  
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  75285
  
  DOI: 10.1038/s41586-024-08575-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11922742/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma

1
1. scibot 13 Aug 2024
  
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  DOI: 10.1038/s43018-023-00721-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11056318/
Apr 2024
www.embopress.org www.embopress.org

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia

2
1. scibot 23 Apr 2024
  
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  plasmid_75285
  
  DOI: 10.1038/s44318-024-00065-w
  
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2. scibot 23 Apr 2024
  
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  plasmid_75285
  
  DOI: 10.1038/s44318-024-00065-w
  
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embopress.org/doi/10.1038/s44318-024-00065-w
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia

1
1. scibot 19 Apr 2024
  
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  plasmid_75285
  
  DOI: 10.1038/s44318-024-00065-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid

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1. scibot 06 Feb 2024
  
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  Addgene_75285
  
  DOI: 10.1158/2159-8290.CD-22-0982
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10524862/
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Lactate activates the mitochondrial electron transport chain independently of its metabolism

1
1. scibot 28 Oct 2023
  
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  RRID:Addgene_75285
  
  DOI: 10.1016/j.molcel.2023.09.034
  
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sciencedirect.com/science/article/pii/S1097276523008006
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition

1
1. scibot 09 Jun 2023
  
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  RRID:Addgene_75285
  
  DOI: 10.1016/j.celrep.2023.112616
  
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sciencedirect.com/science/article/pii/S2211124723006277
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade

1
1. scibot 07 Apr 2023
  
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  addgene_75285
  
  DOI: 10.1101/2023.03.21.533091
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10055208/
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells

1
1. scibot 03 Nov 2022
  
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  plasmid_75285
  
  DOI: 10.1016/j.molcel.2022.10.005
  
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sciencedirect.com/science/article/pii/S1097276522009625
Sep 2021
www.sciencedirect.com www.sciencedirect.com

A hydride transfer complex reprograms NAD metabolism and bypasses senescence

1
1. scibot 23 Sep 2021
  
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  Addgene_75285
  
  DOI: 10.1016/j.molcel.2021.08.028
  
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sciencedirect.com/science/article/pii/S109727652100695X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Local Mitochondrial ATP Production Regulates Endothelial Fatty Acid Uptake and Transport

2
1. scibot 29 Apr 2021
  
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  Cat#75285
  
  DOI: 10.1016/j.cmet.2020.05.018
  
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  RRID:Addgene_75285 RRIDCUR:Missing
2. scibot 29 Apr 2021
  
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  addgene_75285
  
  DOI: 10.1016/j.cmet.2020.05.018
  
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sciencedirect.com/science/article/pii/S1550413120302576
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

1
1. scibot 05 Jan 2021
  
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  RRID:Addgene_75285
  
  DOI: 10.1016/j.molcel.2020.12.012
  
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  RRIDCUR:Validated RRID:Addgene_75285
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sciencedirect.com/science/article/pii/S1097276520309047