Hypothesis

12 Matching Annotations

Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation

1
1. scibot 15 Jun 2025
  
  in Public
  
  Addgene_80
  
  DOI: 10.1186/s13059-025-03640-4
  
  Resource: None
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427 RRIDCUR:Incorrect RRIDCUR:Unresolved
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RRIDCUR:Incorrect

RRIDCUR:Unresolved

RRID:Addgene_80427

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12164210/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

GluN2B-mediated regulation of silent synapses for receptor specification and addiction memory

1
1. scibot 11 Mar 2025
  
  in Public
  
  80427
  
  DOI: 10.1038/s12276-025-01399-z
  
  Resource: RRID:Addgene_80427
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427
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RRID:Addgene_80427

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11873126/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ErbB4 precludes the occurrence of PTSD-like fear responses by supporting the bimodal activity of the central amygdala

1
1. scibot 29 Dec 2024
  
  in Public
  
  plasmid_80427
  
  DOI: 10.1038/s12276-024-01365-1
  
  Resource: RRID:Addgene_80427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427
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RRID:Addgene_80427

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11671592/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Generation of a homozygous (MCRIi031-A-3) WT1 knockout human iPSC line

1
1. scibot 19 Jul 2024
  
  in Public
  
  Addgene_80427
  
  DOI: 10.1016/j.scr.2024.103494
  
  Resource: RRID:Addgene_80427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427
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RRID:Addgene_80427

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scibot

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sciencedirect.com/science/article/pii/S1873506124001922
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines

2
1. scibot 05 Mar 2024
  
  in Public
  
  Addgene_80427
  
  DOI: 10.1016/j.scr.2024.103374
  
  Resource: RRID:Addgene_80427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427
2. scibot 05 Mar 2024
  
  in Public
  
  Addgene_80427
  
  DOI: 10.1016/j.scr.2024.103374
  
  Resource: RRID:Addgene_80427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427
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RRID:Addgene_80427

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scibot

URL

sciencedirect.com/science/article/pii/S1873506124000722
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.1290A>G (p.T351A) or c.2067A>G (p.T610A) in the RHOT1 gene encoding Miro1

1
1. scibot 28 Mar 2023
  
  in Public
  
  Addgene_80427
  
  DOI: 10.1016/j.scr.2023.103085
  
  Resource: RRID:Addgene_80427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_80427
  
  What is this?
  
  RRID:Addgene_80427
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RRID:Addgene_80427

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scibot

URL

sciencedirect.com/science/article/pii/S1873506123000715
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Generation and heterozygous repair of human iPSC lines from three individuals with cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) carrying biallelic AAGGG expansions in RFC1

1
1. scibot 16 Feb 2023
  
  in Public
  
  plasmid_80427
  
  DOI: 10.1016/j.scr.2023.103047
  
  Resource: RRID:Addgene_80427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427
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RRID:Addgene_80427

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scibot

URL

sciencedirect.com/science/article/pii/S1873506123000338
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Using CRISPR/Cas9 to generate a heterozygous COL2A1 p.R719C iPSC line (MCRIi019-A-6) model of human precocious osteoarthritis

1
1. scibot 07 Jan 2023
  
  in Public
  
  RRID:Addgene_80427
  
  DOI: 10.1016/j.scr.2023.103020
  
  Resource: RRID:Addgene_80427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427
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RRID:Addgene_80427

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scibot

URL

sciencedirect.com/science/article/pii/S1873506123000065
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Generation of a heterozygous COL2A1 (p.G1113C) hypochondrogenesis mutation iPSC line, MCRIi019-A-7, using CRISPR/Cas9 gene editing

1
1. scibot 26 Aug 2021
  
  in Public
  
  Addgene_80427
  
  DOI: 10.1016/j.scr.2021.102515
  
  Resource: RRID:Addgene_80427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_80427
  
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  RRID:Addgene_80427
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RRID:Addgene_80427

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scibot

URL

sciencedirect.com/science/article/pii/S1873506121003627
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Generation of a miR-26b stem-loop knockout human iPSC line, MCRIi019-A-1, using CRISPR/Cas9 editing

1
1. scibot 16 Dec 2020
  
  in Public
  
  Addgene_80427
  
  DOI: 10.1016/j.scr.2020.102118
  
  Resource: RRID:Addgene_80427
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_80427
  
  What is this?
  
  RRID:Addgene_80427 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_80427

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scibot

URL

sciencedirect.com/science/article/pii/S1873506120304190
Sep 2020
www.sciencedirect.com www.sciencedirect.com

CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A

1
1. scibot 09 Sep 2020
  
  in Public
  
  Addgene_80427
  
  DOI: 10.1016/j.scr.2020.101962
  
  Resource: RRID:Addgene_80427
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_80427
  
  What is this?
  
  RRID:Addgene_80427 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_80427

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scibot

URL

sciencedirect.com/science/article/pii/S1873506120302634