44 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
    2
    1. scibot 26 Apr 2024
      Addgene, Cat# 83480

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    2. scibot 26 Apr 2024
      plasmid_83480

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    sciencedirect.com/science/article/pii/S0092867424003131
  3. rupress.org rupress.org
    Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization
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    1. scibot 25 Apr 2024
      RRID:Addgene_83480

      DOI: 10.1083/jcb.202307026

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    2. scibot 25 Apr 2024
      RRID:Addgene_83480

      DOI: 10.1083/jcb.202307026

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    rupress.org/jcb/article/223/4/e202307026/276570/Tunable-DNMT1-degradation-reveals-DNMT1-DNMT3B
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Scribble/SGEF/Dlg1 complex regulates the stability of apical junctions in epithelial cells
    1
    1. scibot 23 Apr 2024
      83480

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996629/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation by the RNA-binding protein Unkempt at its effector interface
    1
    1. scibot 23 Apr 2024
      83480

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009413/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global and single-nucleotide resolution detection of 7-methylguanosine in RNA
    1
    1. scibot 14 Apr 2024
      83,480

      DOI: 10.1080/15476286.2024.2337493

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993922/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis
    1
    1. scibot 13 Apr 2024
      83480

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    ncbi.nlm.nih.gov/pmc/articles/PMC10987646/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells
    1
    1. scibot 13 Apr 2024
      Addgene_83480

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    ncbi.nlm.nih.gov/pmc/articles/PMC10997609/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB–dependent IFITM3 expression
    1
    1. scibot 13 Apr 2024
      Addgene_83480

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    ncbi.nlm.nih.gov/pmc/articles/PMC11001640/
  10. Mar 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A SWI/SNF-dependent transcriptional regulation mediated by POU2AF2/C11orf53 at enhancer
    1
    1. scibot 17 Mar 2024
      83480

      DOI: 10.1038/s41467-024-46492-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920751/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein supersaturation powers innate immune signaling
    1
    1. scibot 17 Mar 2024
      Addgene_83480

      DOI: 10.1101/2023.03.20.533581

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    ncbi.nlm.nih.gov/pmc/articles/PMC10055258/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition
    1
    1. scibot 08 Mar 2024
      83480

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907621/
  14. Feb 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer
    1
    1. scibot 29 Feb 2024
      83480

      DOI: 10.1128/jvi.01726-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10878100/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue-location-specific transcription programs drive tumor dependencies in colon cancer
    1
    1. scibot 21 Feb 2024
      83480

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    ncbi.nlm.nih.gov/pmc/articles/PMC10869357/
  17. www.biorxiv.org www.biorxiv.org
    Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications
    1
    1. scibot 15 Feb 2024
      Addgene_83480

      DOI: 10.1101/2023.12.16.571619

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    biorxiv.org/content/10.1101/2023.12.16.571619v1
  18. www.sciencedirect.com www.sciencedirect.com
    Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing
    2
    1. scibot 15 Feb 2024
      plasmid_83480

      DOI: 10.1016/j.celrep.2024.113765

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    2. scibot 15 Feb 2024
      plasmid_83480

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    sciencedirect.com/science/article/pii/S2211124724000937
  19. www.sciencedirect.com www.sciencedirect.com
    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
    1
    1. scibot 09 Feb 2024
      Plasmid_83480

      DOI: 10.1016/j.cels.2024.01.001

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    sciencedirect.com/science/article/pii/S240547122400022X
  20. Dec 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Synonymous codon usage regulates translation initiation
    1
    1. scibot 17 Dec 2023
      Addgene_83480

      DOI: 10.1016/j.celrep.2023.113413

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    sciencedirect.com/science/article/pii/S2211124723014250
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity
    1
    1. scibot 07 Dec 2023
      RRID:Addgene_83480

      DOI: 10.1371/journal.pbio.3002381

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    ncbi.nlm.nih.gov/pmc/articles/PMC10695362/
  23. Nov 2023
  24. www.sciencedirect.com www.sciencedirect.com
    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
    1
    1. scibot 17 Nov 2023
      RRID:Addgene_83480

      DOI: 10.1016/j.devcel.2023.10.010

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    sciencedirect.com/science/article/pii/S1534580723005518
  25. Oct 2023
  26. www.sciencedirect.com www.sciencedirect.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
    1
    1. scibot 28 Oct 2023
      Addgene_83480

      DOI: 10.1016/j.cmet.2023.09.012

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    sciencedirect.com/science/article/pii/S1550413123003686
  27. www.cell.com www.cell.com
    MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
    1
    1. scibot 06 Oct 2023
      RRID:Addgene_83480

      DOI: 10.1016/j.celrep.2023.113023

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    cell.com/cell-reports/abstract/S2211-1247(23)01034-3
  28. May 2023
  29. www.biorxiv.org www.biorxiv.org
    Copyback viral genomes trigger stress granule formation independent of the antiviral response to interfere with viral translation in acute and persistent infections
    1
    1. scibot 25 May 2023
      RRID:Addgene_83480

      DOI: 10.1101/2023.05.17.541157

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    biorxiv.org/content/10.1101/2023.05.17.541157v1
  30. Mar 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma
    1
    1. scibot 11 Mar 2023
      Plasmid_83480

      DOI: 10.1016/j.celrep.2023.112212

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    sciencedirect.com/science/article/pii/S2211124723002231
  32. Feb 2023
  33. www.sciencedirect.com www.sciencedirect.com
    An adverse tumor-protective effect of IDO1 inhibition
    1
    1. scibot 23 Feb 2023
      RRID:Addgene_83480

      DOI: 10.1016/j.xcrm.2023.100941

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    sciencedirect.com/science/article/pii/S2666379123000332
  34. Dec 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Generation of human induced pluripotent stem cell lines with HMOX1 promoter polymorphism and CRISPR/Cas9-mediated deletion of exon 50 of DMD gene
    1
    1. scibot 17 Dec 2022
      RRID:Addgene_83480

      DOI: 10.1016/j.scr.2022.103004

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    sciencedirect.com/science/article/pii/S1873506122003531
  36. Jun 2022
  37. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
    1
    1. scibot 10 Jun 2022
      RRID:Addgene_83480

      DOI: 10.1016/j.xcrm.2022.100655

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    sciencedirect.com/science/article/pii/S2666379122001872
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SETDB1–TRIM28 complex suppresses antitumor immunity
    1
    1. scibot 07 Jun 2022
      RRID:Addgene_83480

      DOI: 10.1158/2326-6066.CIR-21-0754

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    ncbi.nlm.nih.gov/pmc/articles/PMC8647838/
  39. May 2022
  40. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
    1
    1. scibot 11 May 2022
      Addgene: #83480

      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  41. Apr 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antithetic effect of interferon-α on cell-free and cell-to-cell HIV-1 infection
    1
    1. scibot 27 Apr 2022
      RRID:Addgene_83480

      DOI: 10.1371/journal.pcbi.1010053

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    ncbi.nlm.nih.gov/pmc/articles/PMC9037950/
  43. Mar 2022
  44. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
    1
    1. scibot 11 Mar 2022
      RRID:Addgene_83480

      DOI: 10.7554/eLife.73150

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    elifesciences.org/articles/73150
  45. Feb 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.xgen.2022.100095

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    sciencedirect.com/science/article/pii/S2666979X2200012X
  47. www.sciencedirect.com www.sciencedirect.com
    Sparse dictionary learning recovers pleiotropy from human cell fitness screens
    1
    1. scibot 02 Feb 2022
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      DOI: 10.1016/j.cels.2021.12.005

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    sciencedirect.com/science/article/pii/S2405471221004889
  48. Sep 2021
  49. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
    1
    1. scibot 28 Sep 2021
      RRID:Addgene_83480

      DOI: 10.1016/j.cell.2021.09.006

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    sciencedirect.com/science/article/pii/S0092867421010539
  50. www.sciencedirect.com www.sciencedirect.com
    Title: Derivation of human pluripotent stem cell line via CRISPR/Cas9 mediated deletion of exon 3 LAMA2 gene (DMBi001-A-1)
    1
    1. scibot 03 Sep 2021
      RRID:Addgene_83480

      DOI: 10.1016/j.scr.2021.102529

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    sciencedirect.com/science/article/pii/S1873506121003767
  51. Aug 2021
  52. elifesciences.org elifesciences.org
    GIPC proteins negatively modulate Plexind1 signaling during vascular development
    1
    1. scibot 13 Aug 2021
      plasmid_83480

      DOI: 10.7554/eLife.30454

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    elifesciences.org/articles/30454
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 03 Aug 2021
      plasmid_83480

      DOI: 10.7554/eLife.30454

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    ncbi.nlm.nih.gov/pmc/articles/PMC6499541/
  54. May 2021
  55. www.sciencedirect.com www.sciencedirect.com
    A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation
    1
    1. scibot 01 May 2021
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    sciencedirect.com/science/article/pii/S1550413121000139
  56. Nov 2020
  57. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
    1
    1. scibot 03 Nov 2020
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      DOI: 10.1016/j.molcel.2020.10.005

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    pubmed.ncbi.nlm.nih.gov/33108759/
  58. Jan 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_83480

      DOI: 10.1016/j.celrep.2019.08.060

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    sciencedirect.com/science/article/pii/S2211124719311088
  60. www.sciencedirect.com www.sciencedirect.com
    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_83480

      DOI: 10.1016/j.cell.2019.06.014

      Resource: RRID:Addgene_83480

      Curator: @ethanbadger

      SciCrunch record: RRID:Addgene_83480

      What is this?

      RRID:Addgene_83480 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419306774