45 Matching Annotations
  1. Jul 2026
  2. www.biorxiv.org www.biorxiv.org
    Vertical inhibition of the autophagy pathway impairs growth and enhances sensitivity to mTORC1 inhibition in pancreatic ductal adenocarcinoma
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    biorxiv.org/content/10.64898/2026.06.28.734981v1
  3. Mar 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Targeting the ferritinophagy-lysosome axis as a therapeutic vulnerability in gastroenteropancreatic neuroendocrine tumors
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    sciencedirect.com/science/article/pii/S2666379126001126
  5. Feb 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A dose-dependent switch in translation capacity controls the transcription factor response to H2O2 stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12873884/
  7. Nov 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Fanconi anemia proteins causes a reliance on lysosomal exocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586712/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative Profiling and Chemogenomics Application of Chemical Tools for NR4A Nuclear Receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12516683/
  10. Oct 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve is a Therapeutic Strategy for Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11999774/
  12. www.sciencedirect.com www.sciencedirect.com
    The role of MRGPRX1 in the melanogenesis of human primary epidermal melanocytes
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    sciencedirect.com/science/article/pii/S0022202X25024753
  13. Sep 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Atypical cadherin FAT1 promotes tumorigenesis by suppressing autophagic cell death in glioblastoma under hypoxia or nutrient stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409952/
  15. Aug 2025
  16. www.sciencedirect.com www.sciencedirect.com
    YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition
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    sciencedirect.com/science/article/pii/S2211124725009593
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H3K36me2 methyltransferase NSD2/WHSC1 promotes triple-negative breast cancer metastasis via activation of ULK1-dependent autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283020/
  18. Jul 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ambroxol induces myeloma cell death by inhibiting autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12197993/
  20. Jun 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12126518/
  22. May 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acinetobacter baumannii OmpA hinders host autophagy via the CaMKK2-reliant AMPK-pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11980379/
  24. Apr 2025
  25. www.nature.com www.nature.com
    Targeting PIKfyve-driven lipid metabolism in pancreatic cancer
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    nature.com/articles/s41586-025-08917-z
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interplay between ALK2R206H mutant receptor and autophagy signaling regulates receptor stability and its chondrogenic functions
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    pmc.ncbi.nlm.nih.gov/articles/PMC11929866/
  27. Mar 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11970383/
  29. Feb 2025
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The Yeast-Fermented Garlic and a Balance of Spermine/Spermidine Activates Autophagy via EGR1 Transcriptional Factor
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    onlinelibrary.wiley.com/doi/10.1002/mnfr.202400606
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11809384/
  32. link.springer.com link.springer.com
    The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling
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    link.springer.com/article/10.1038/s41467-025-56631-1
  33. Jan 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cholesterol deficiency directs autophagy-dependent secretion of extracellular vesicles
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    pmc.ncbi.nlm.nih.gov/articles/PMC11741461/
  35. Nov 2024
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of polo‐like kinases 2 in the proteasomal and lysosomal degradation of alpha‐synuclein in neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11580719/
  37. Jul 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemogenomics for NR1 nuclear hormone receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11189487/
  39. Jun 2024
  40. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
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    sciencedirect.com/science/article/pii/S0092867424005762
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2–BECN1 interaction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11119520/
  42. Apr 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983929/
  44. Mar 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NME3 is a gatekeeper for DRP1-dependent mitophagy in hypoxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10938004/
  46. Feb 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    5-ALA localises to the autophagy compartment and increases its fluorescence upon autophagy enhancement through caloric restriction and spermidine treatment in human glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10823107/
  48. Sep 2023
  49. link.springer.com link.springer.com
    Induction of proteasomal activity in mammalian cells by lifespan-extending tRNA synthetase inhibitors
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    link.springer.com/article/10.1007/s11357-023-00938-8
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic target of rapamycin (mTOR) regulates self-sustained quiescence, tumor indolence, and late clinical metastasis in a Beclin-1-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC9928463/
  51. Aug 2023
  52. www.mdpi.com www.mdpi.com
    Ferulic Acid Induces Autophagy and Apoptosis in Colon Cancer CT26 Cells via the MAPK Pathway
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    mdpi.com/1420-3049/28/16/6014
  53. www.biorxiv.org www.biorxiv.org
    The endosomal sorting complex Retromer has a central role in systemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes
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    biorxiv.org/content/10.1101/2023.08.09.552611v2
  54. Jul 2023
  55. link.springer.com link.springer.com
    Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology
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    link.springer.com/article/10.1007/s12035-023-03417-5
  56. Dec 2022
  57. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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    sciencedirect.com/science/article/pii/S2211124722015248
  58. Sep 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoskeletal vimentin regulates cell size and autophagy through mTORC1 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC9469959/
  60. Aug 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Non-degradable autophagic vacuoles are indispensable for cell competition
    2
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    sciencedirect.com/science/article/pii/S2211124722011123
  62. Jan 2022
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death
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    ncbi.nlm.nih.gov/pmc/articles/PMC8773829/
  64. Sep 2021
  65. link.springer.com link.springer.com
    CRISPR/Cas-Mediated Knock-in of Genetically Encoded Fluorescent Biosensors into the AAVS1 Locus of Human-Induced Pluripotent Stem Cells
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    link.springer.com/protocol/10.1007/7651_2021_422
  66. Jul 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8254453/
  68. Jun 2021
  69. www.nature.com www.nature.com
    High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol
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    nature.com/articles/s41419-021-03830-5
  70. Feb 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolism, Oxidative Stress and Cell Signaling: Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC7052610/
  72. Dec 2020
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Functional inhibition of heat shock protein 70 by VER‐155008 suppresses pleural mesothelioma cell proliferation via an autophagy mechanism
    1
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    onlinelibrary.wiley.com/doi/full/10.1111/1759-7714.13784
  74. Sep 2020
  75. journals.physiology.org journals.physiology.org
    Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice | American Journal of Physiology-Cell Physiology
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    journals.physiology.org/doi/full/10.1152/ajpcell.00123.2019