34 Matching Annotations
  1. Nov 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 inhibitor exhibits potent antiviral activity and reverses NSP14-driven host modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12583774/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12530129/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disruption of Microhomology-mediated End-joining in Ewing Sarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12191234/
  5. Oct 2025
  6. www.sciencedirect.com www.sciencedirect.com
    Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis
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    sciencedirect.com/science/article/pii/S1550413125004346
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lung cancer–intrinsic SOX2 expression mediates resistance to checkpoint blockade therapy by inducing Treg cell–dependent CD8+ T-cell exclusion
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964848/
  8. Sep 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cyclin D1 overexpression induces replication stress and microhomology-mediated end-joining dependence in mantle cell lymphoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12404763/
  10. Aug 2025
  11. www.sciencedirect.com www.sciencedirect.com
    Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells
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    sciencedirect.com/science/article/pii/S1074761325003176
  12. Jun 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chaperone-mediated insertion of mitochondrial import receptor TOM70 protects against diet-induced obesity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12117470/
  14. May 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984406/
  16. Apr 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optogenetically engineered Septin-7 enhances immune cell infiltration of tumor spheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11536090/
  18. elifesciences.org elifesciences.org
    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
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    elifesciences.org/reviewed-preprints/106492
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952453/
  20. www.sciencedirect.com www.sciencedirect.com
    Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance
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    sciencedirect.com/science/article/pii/S1535610825001321
  21. Feb 2025
  22. dx.doi.org dx.doi.org
    Therapy enhancing chromosome instability may be advantageous for IDH1R132H/WT gliomas
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    dx.doi.org/10.1093/narcan/zcaf003
  23. www.sciencedirect.com www.sciencedirect.com
    ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
    1
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    sciencedirect.com/science/article/pii/S0092867425000960
  24. Sep 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRPF40A induces inclusion of exons in GC-rich regions important for human myeloid cell differentiation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347146/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Excitable Rho dynamics control cell shape and motility by sequentially activating ERM proteins and actomyosin contractility
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11378911/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11378969/
  28. www.sciencedirect.com www.sciencedirect.com
    A TBK1-independent primordial function of STING in lysosomal biogenesis
    1
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    sciencedirect.com/science/article/pii/S1097276524007032
  29. Aug 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11319505/
  31. Jul 2024
  32. www.cell.com www.cell.com
    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
    1
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    cell.com/molecular-cell/fulltext/S1097-2765(24)00538-0
  33. Jun 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of Bispecific T-Cell Engagers Targeting Murine Cytomegalovirus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11209133/
  35. Apr 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
  37. Mar 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repeat DNA methylation is modulated by adherens junction signaling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10920906/
  39. Feb 2024
  40. www.biorxiv.org www.biorxiv.org
    Excitable Rho dynamics drive cell contractions by sequentially inducing ERM protein-mediated actin-membrane attachment and actomyosin contractility
    1
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    biorxiv.org/content/10.1101/2023.12.19.572346v1
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10766649/
  42. Oct 2023
  43. www.cell.com www.cell.com
    MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
    1
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    cell.com/cell-reports/abstract/S2211-1247(23)01034-3
  44. Sep 2022
  45. www.sciencedirect.com www.sciencedirect.com
    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722012566
  46. Jun 2022
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC9356996/
  48. Apr 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
    2
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    sciencedirect.com/science/article/pii/S1535610822001234
  50. Jan 2022
  51. www.sciencedirect.com www.sciencedirect.com
    TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
    2
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    sciencedirect.com/science/article/pii/S1074761321005434
  52. Aug 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy
    1
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    sciencedirect.com/science/article/pii/S1535610821004025