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Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor heterogeneity underlies clinical outcome and MEK inhibitor response in somatic NF1-mutant glioblastoma

1
1. scibot 23 Nov 2025
  
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  85969
  
  DOI: 10.1172/jci.insight.192658
  
  Resource: RRID:Addgene_85969
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12487855/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A transcriptomic, proteomic, and functional genetic atlas dissects neurofibromin function in the peripheral nervous system

1
1. scibot 20 Jul 2025
  
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  85969
  
  DOI: 10.1073/pnas.2506823122
  
  Resource: RRID:Addgene_85969
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12260521/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens

1
1. scibot 15 Jun 2025
  
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  85969
  
  DOI: 10.1038/s41467-025-59948-z
  
  Resource: RRID:Addgene_85969
  
  Curator: @olekpark
  
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  RRID:Addgene_85969
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RRID:Addgene_85969

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12092667/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ASCT2 is a major contributor to serine uptake in cancer cells

1
1. scibot 25 Sep 2024
  
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  Addgene_85969
  
  DOI: 10.1016/j.celrep.2024.114552
  
  Resource: RRID:Addgene_85969
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11406281/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Role of IRF9 Upregulation in Modulating Sensitivity to Olaparib and Platinum-Based Chemotherapies in Breast Cancer

1
1. scibot 31 Jul 2024
  
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  Addgene_85969
  
  DOI: 10.3390/genes15070959
  
  Resource: Addgene_85969
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11276373/
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

2
1. scibot 04 Jun 2024
  
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  Addgene 85969
  
  DOI: 10.1016/j.devcel.2024.05.010
  
  Resource: RRID:Addgene_85969
  
  Curator: @abever99
  
  SciCrunch record: RRID:Addgene_85969
  
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  DOI:10.1016/j.devcel.2024.05.010 RRID:Addgene_85969
2. scibot 04 Jun 2024
  
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  plasmid_85969
  
  DOI: 10.1016/j.devcel.2024.05.010
  
  Resource: RRID:Addgene_85969
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85969
  
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  RRID:Addgene_85969
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DOI:10.1016/j.devcel.2024.05.010

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scibot

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sciencedirect.com/science/article/pii/S1534580724003277
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments

1
1. scibot 19 May 2024
  
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  Addgene_85969
  
  DOI: 10.1038/s41556-024-01402-1
  
  Resource: RRID:Addgene_85969
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11098743/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Improving prime editing with an endogenous small RNA-binding protein

1
1. scibot 23 Apr 2024
  
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  85969
  
  DOI: 10.1038/s41586-024-07259-6
  
  Resource: RRID:Addgene_85969
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11023932/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance

1
1. scibot 05 Feb 2024
  
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  85969
  
  DOI: 10.1038/s41467-024-44755-9
  
  Resource: RRID:Addgene_85969
  
  Curator: @olekpark
  
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  RRID:Addgene_85969
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ncbi.nlm.nih.gov/pmc/articles/PMC10786885/
Jan 2023
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

1
1. scibot 11 Jan 2023
  
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  Addgene_85969
  
  DOI: 10.7554/eLife.81856
  
  Resource: RRID:Addgene_85969
  
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  RRID:Addgene_85969
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pubmed.ncbi.nlm.nih.gov/36576240/
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation

1
1. scibot 02 Dec 2022
  
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  Addgene_85969
  
  DOI: 10.1016/j.celrep.2022.111630
  
  Resource: RRID:Addgene_85969
  
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  RRID:Addgene_85969
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ncbi.nlm.nih.gov/pmc/articles/PMC9687083/
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis

1
1. scibot 20 Oct 2022
  
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  plasmid_85969
  
  DOI: 10.1016/j.celrep.2022.111514
  
  Resource: RRID:Addgene_85969
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85969
  
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  RRID:Addgene_85969
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sciencedirect.com/science/article/pii/S221112472201364X
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multiplex T-cell Stimulation Assay Utilizing a T-cell Activation Reporter-based Detection System

1
1. scibot 22 Jan 2022
  
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  RRID:Addgene_85969
  
  DOI: 10.21769/BioProtoc.3883
  
  Resource: RRID:Addgene_85969
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85969
  
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  RRID:Addgene_85969
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ncbi.nlm.nih.gov/pmc/articles/PMC7953253/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity

1
1. scibot 30 Jul 2021
  
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  RRID:Addgene_85969
  
  DOI: 10.7554/eLife.50036
  
  Resource: RRID:Addgene_85969
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_85969
  
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  RRID:Addgene_85969 RRIDCUR:Unrecognized
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RRID:Addgene_85969

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ncbi.nlm.nih.gov/pmc/articles/PMC6897534/
Oct 2020
www.sciencedirect.com www.sciencedirect.com

Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells

1
1. scibot 31 Oct 2020
  
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  Addgene_85969
  
  DOI: 10.1016/j.cels.2020.10.002
  
  Resource: RRID:Addgene_85969
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_85969
  
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  RRIDCUR:Validated RRID:Addgene_85969
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S2405471220303707
Sep 2020
www.frontiersin.org www.frontiersin.org

Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System

1
1. scibot 10 Sep 2020
  
  in Public
  
  RRID:Addgene_85969
  
  DOI: 10.3389/fimmu.2020.00633
  
  Resource: RRID:Addgene_85969
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_85969
  
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  RRIDCUR:Validated RRID:Addgene_85969
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RRID:Addgene_85969

RRIDCUR:Validated

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scibot

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frontiersin.org/article/10.3389/fimmu.2020.00633/full