56 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative CRISPR Screening and RNA Analyses Discover an Essential Role for PUF60 Interactions with 3' Splice Sites in Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12911328/
  3. Jan 2026
  4. pubs.acs.org pubs.acs.org
    Indocyanine Green-Labeled Antibodies Cotargeting CDCP1 and Mesothelin for Fluorescence-Guided Imaging of Pancreatic Cancer
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    pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.5c01452
  5. www.sciencedirect.com www.sciencedirect.com
    Uncovering genetic interactions in the DNA repair network in response to endogenous damage and ionizing radiation
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    sciencedirect.com/science/article/pii/S2211124725016225
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    gkaf1437-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12774638/
  7. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225028536-main-html.html
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    54.241.53.176/240dc6a05105efbe0d3f771207c7fadaa29f2101/1-s2.0-S2589004225028536-main-html.html
  8. Nov 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12582121/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppressing protein damage response to overcome multidrug resistance in cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12484725/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome‐Wide CRISPR/Cas9 Screening Identifies the COMMANDER Recycling Complex as a Key Player in EV Uptake
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    pmc.ncbi.nlm.nih.gov/articles/PMC12456102/
  12. Oct 2025
  13. www.nature.com www.nature.com
    Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumors
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    nature.com/articles/s41467-025-64255-8
  14. Aug 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARP1 and PARP2 are dispensable for DNA repair by microhomology-mediated end-joining during mitosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12259053/
  16. Jul 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Time-resolved mitochondrial screen identifies regulatory components of oxidative metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12187934/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The nucleosome remodeling and deacetylase-SWItch/sucrose non-fermentable antagonism regulates the coordinated activation of epithelial-to-mesenchymal transition and inflammation in oral cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12229464/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281435/
  20. Mar 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The essential clathrin adapter protein complex-2 is tumor suppressive specifically in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11885535/
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    Engineering mtDNA deletions by reconstituting end joining in human mitochondria
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    sciencedirect.com/science/article/pii/S0092867425001941
  23. Feb 2025
  24. journals.asm.org journals.asm.org
    Epstein-Barr virus replication within differentiated epithelia requires pRb sequestration of activator E2F transcription factors
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    journals.asm.org/doi/10.1128/jvi.00995-24
  25. Dec 2024
  26. www.sciencedirect.com www.sciencedirect.com
    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    sciencedirect.com/science/article/pii/S0092867424013266
  27. Sep 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stat3-mediated Atg7 expression regulates anti-tumor immunity in mouse melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11377374/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys
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    ncbi.nlm.nih.gov/pmc/articles/PMC11324798/
  30. Aug 2024
  31. www.sciencedirect.com www.sciencedirect.com
    In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S266637912400377X
  32. Jul 2024
  33. www.cell.com www.cell.com
    Genome-scale exon perturbation screens uncover exons critical for cell fitness
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    cell.com/molecular-cell/abstract/S1097-2765(24)00447-7
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stat3-mediated Atg7 expression enhances anti-tumor immunity in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11195126/
  35. Jun 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in retinal pigment epithelium
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    ncbi.nlm.nih.gov/pmc/articles/PMC11144268/
  37. May 2024
  38. www.sciencedirect.com www.sciencedirect.com
    TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
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    sciencedirect.com/science/article/pii/S2211124724005424
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAPK phosphatase 1 inhibition of p38α within lung myofibroblasts is essential for spontaneous fibrosis resolution
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    ncbi.nlm.nih.gov/pmc/articles/PMC11093610/
  40. www.cell.com www.cell.com
    Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders
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    cell.com/iscience/abstract/S2589-0042(24)01024-1
  41. 52.53.155.43 52.53.155.43
    2024.04.30.591961v1.full-html.html
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  42. Apr 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11043890/
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    Protocol for efficient CRISPR-Cas9-mediated fluorescent tag knockin in hard-to-transfect erythroid cell lines
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    sciencedirect.com/science/article/pii/S2666166724001813
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10957915/
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    EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
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    sciencedirect.com/science/article/pii/S2211124721001972
  47. Feb 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10867109/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849215/
  50. Jan 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADP-Ribosylation Factor-Interacting Protein 2 Acts as a Novel Regulator of Mitophagy and Autophagy in Podocytes in Diabetic Nephropathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10812550/
  52. Dec 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Wildtype C-Raf gene dosage and dimerization drive prostate cancer metastasis
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    sciencedirect.com/science/article/pii/S2589004223025579
  54. Aug 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder
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    ncbi.nlm.nih.gov/pmc/articles/PMC10405067/
  56. Jul 2023
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4-mediated Ferroptosis in Colorectal Cancer
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    onlinelibrary.wiley.com/doi/10.1002/advs.202301088
  58. www.sciencedirect.com www.sciencedirect.com
    Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons
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    sciencedirect.com/science/article/pii/S2589004223011215
  59. Jun 2023
  60. www.nature.com www.nature.com
    Intracellular pH dynamics regulates intestinal stem cell lineage specification
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    nature.com/articles/s41467-023-39312-9
  61. May 2023
  62. gut.bmj.com gut.bmj.com
    Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models
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    gut.bmj.com/content/early/2022/06/21/gutjnl-2022-327121
  63. Mar 2023
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of karyopherin β1-mediated nuclear import disrupts oncogenic lineage- defining transcription factor activity in small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9444950/
  65. Jul 2022
  66. 52.53.155.43 52.53.155.43
    can-21-3713-html.html
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  67. Apr 2022
  68. jasn.asnjournals.org jasn.asnjournals.org
    α-Parvin Defines a Specific Integrin Adhesome to Maintain the Glomerular Filtration Barrier
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    jasn.asnjournals.org/content/33/4/786
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NUP133 Controls Nuclear Pore Assembly, Transcriptome Composition, and Cytoskeleton Regulation in Podocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9025798/
  70. Feb 2022
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8807877/
  72. Jan 2022
  73. www.sciencedirect.com www.sciencedirect.com
    scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
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    sciencedirect.com/science/article/pii/S1097276521011436
  74. Nov 2021
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold
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    ncbi.nlm.nih.gov/pmc/articles/PMC8519919/
  76. Jul 2021
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Double‐strand breakage in the extrachromosomal double minutes triggers their aggregation in the nucleus, micronucleation, and morphological transformation
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    onlinelibrary.wiley.com/doi/10.1002/gcc.22810
  78. Apr 2021
  79. www.sciencedirect.com www.sciencedirect.com
    The bone microenvironment invigorates metastatic seeds for further dissemination
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    sciencedirect.com/science/article/pii/S0092867421002968
  80. Mar 2021
  81. www.sciencedirect.com www.sciencedirect.com
    EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
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    sciencedirect.com/science/article/pii/S2211124721001972
  82. Feb 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Derivation of Stem Cell Line UMi028-A-2 Containing a CRISPR/Cas9 Induced Alzheimer’s Disease Risk Variant p.S1038C in the TTC3 gene
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    sciencedirect.com/science/article/pii/S1873506121001045
  84. Jan 2020
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Double‐strand breakage in the extrachromosomal double minutes triggers their aggregation in the nucleus, micronucleation, and morphological transformation
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    onlinelibrary.wiley.com/doi/10.1002/gcc.22810