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    Deprivation of EGFR signal causes senolysis in PDAC with CDK4/6 inhibition
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    nature.com/articles/s41418-025-01634-0
  3. Nov 2025
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    StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models
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    sciencedirect.com/science/article/pii/S0092867425011365
  5. Oct 2025
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    Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202501791
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    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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    Antibody-gamma/delta T cell receptors targeting GPC2 regress neuroblastoma with low antigen density
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  10. Sep 2025
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    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
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    Dual Inhibition of Carbonic Anhydrase IX and Glutathione Peroxidase 4 as a Novel Strategy for Ferroptosis-Induced Tumor Cell Death
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  14. Aug 2025
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    Oncogenic KRAS Mutations Confer a Unique Mechanotransduction Response to Peristalsis in Colorectal Cancer Cells
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  16. Jun 2025
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    Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones
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  19. May 2025
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    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    elifesciences.org/reviewed-preprints/106511
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPDPF is not a key regulator of human pancreas development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037078/
  22. Apr 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70022
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  26. Jan 2025
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    FGFR2-RUNX2 activation: An unexplored therapeutic pathway in luminal breast cancer related to tumor progression
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35302
  28. Dec 2024
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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  30. Nov 2024
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  32. Aug 2024
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    The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer
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  34. Jul 2024
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    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
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  36. Jun 2024
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    Comparable efficacy of oral bendamustine versus intravenous administration in treating hematologic malignancies
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  38. May 2024
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    PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival
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  40. Mar 2024
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    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
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  42. Feb 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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  44. Oct 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10561629/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
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  47. Sep 2023
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    Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
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  49. Aug 2023
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  51. Jun 2023
  52. www.nature.com www.nature.com
    Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
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  53. dx.doi.org dx.doi.org
    Monitoring Therapeutic Response to Anti-Fibroblast Activation Protein (FAP) CAR T Cells using [18F]AlF-FAPI-74
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    dx.doi.org/10.1158/1078-0432.CCR-22-1379
  54. Apr 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryopreserved PM21-Particle-Expanded Natural Killer Cells Maintain Cytotoxicity and Effector Functions In Vitro and In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC9022621/
  57. Feb 2022
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A 3D Platform to Investigate Dynamic Cell-to-Cell Interactions Between Tumor Cells and Mesenchymal Progenitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8802911/
  59. Oct 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC8533699/
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    Anti-GD2 CAR MSCs against metastatic Ewing's sarcoma
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    sciencedirect.com/science/article/pii/S1936523321002321
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    Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas
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  63. Aug 2021
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  65. Jul 2021
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    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rejection of benign melanocytic nevi by nevus-resident CD4+ T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8221625/
  68. www.nature.com www.nature.com
    Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip
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    nature.com/articles/s41551-021-00757-2
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hormonal regulation of Semaphorin 7a in ER+ breast cancer drives therapeutic resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC7878309/
  70. May 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC8124877/
  72. Apr 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S1934590921001119
  74. www.sciencedirect.com www.sciencedirect.com
    Defining the Teratoma as a Model for Multi-lineage Human Development
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    sciencedirect.com/science/article/pii/S0092867420313817
  75. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors
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    sciencedirect.com/science/article/pii/S2666379121000434
  76. Sep 2020
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    Establishment and Use of Patient-Derived Xenograft Models for Drug Testing in Head and Neck Squamous Cell Carcinoma
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  78. Jan 2020
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    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    sciencedirect.com/science/article/pii/S1535610819302983
  80. Nov 2018
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    Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S2211124718315675