74 Matching Annotations
  1. Oct 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    dMyc suppresses CTG-induced cytotoxicity in the Drosophila model of DM1 by reducing autophagy and cell death
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    pmc.ncbi.nlm.nih.gov/articles/PMC13223253/
  3. Sep 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Excessive activation of the RAS/MAPK pathway triggers adult-onset motor axonal degeneration
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    sciencedirect.com/science/article/pii/S2589004226028865
  5. www.biorxiv.org www.biorxiv.org
    The human leukemic fusion protein MLL-AF4 promotes autophagy and cell death in the fat body of Drosophila melanogaster
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    biorxiv.org/content/10.64898/2026.07.01.735327v1
  6. Aug 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-saturated-fat diet drives female-biased neurodegeneration in Drosophila via oxidative stress and impaired autophagic flux
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    pmc.ncbi.nlm.nih.gov/articles/PMC13311100/
  8. Jul 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The exocyst complex controls multiple events in the pathway of regulated exocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11588341/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Asparagine prevents intestinal stem cell aging via the autophagy‐lysosomal pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984690/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ceramide lowering rescues respiratory defects in a Drosophila model of acid sphingomyelinase deficiency
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    pmc.ncbi.nlm.nih.gov/articles/PMC11630749/
  12. May 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Decline in Follicle Cell Function Is a Major Driver of Drosophila Ovarian Aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC13132801/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interactions between the myosin Dachs, the adaptor Dlish, and the palmitoyltransferase Approximated mediate Fat-Dachsous signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13104975/
  15. Apr 2026
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pharmacological inhibition of USP14 delays proteostasis-associated aging in a proteasome-dependent but foxo-independent manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC11587835/
  17. 54.241.53.176 54.241.53.176
    Interplay between autophagy and CncC regulates dendrite pruning in <i>Drosophila</i>
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    54.241.53.176/9d1a3ccf243a331fb57a26beb6b8533f66aec49c/PMID_38408233-html.html
  18. Mar 2026
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A decline in follicle cell function is a major driver of Drosophila ovarian aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC12889692/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS in Drosophila glia
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12780286/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non‐apoptotic caspase activation ensures the homeostasis of ovarian somatic stem cells
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC10240206/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autophagy impairment and lifespan reduction caused by Atg1 RNAi or Atg18 RNAi expression in adult fruit flies (Drosophila melanogaster)
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    pmc.ncbi.nlm.nih.gov/articles/PMC11491525/
  23. Feb 2026
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila D-idua Reduction Mimics Mucopolysaccharidosis Type I Disease-Related Phenotypes
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC8750945/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC10444890/
  26. Jan 2026
  27. 54.241.53.176 54.241.53.176
    ut0001-10.1080_15548627.2025.2541384-html.html
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    54.241.53.176/16a695ee84093c1724cfce6cd200a12993ff63d8/ut0001-10.1080_15548627.2025.2541384-html.html
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The cell autonomous and non-autonomous functions of Rab27 in longevity and neuroprotection in Drosophila
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12758210/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adaptation to hypoxia in Drosophila melanogaster requires autophagy
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC9037493/
  30. Dec 2025
  31. 54.241.53.176 54.241.53.176
    PMID_34085929-html.html
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    54.241.53.176/79eded9f15d9fd63f6a21b008d7c0b526be0ce50/PMID_34085929-html.html
  32. Nov 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTPN9-mediated dephosphorylation of VTI1B promotes ATG16L1 precursor fusion and autophagosome formation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC8526009/
  34. Oct 2025
  35. 54.241.53.176 54.241.53.176
    PMID_32427101-html.html
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    54.241.53.176/6b90ac7fdc9d2420f1d4718eeb6141f32abdc19f/PMID_32427101-html.html
  36. Sep 2025
  37. 52.53.155.43 52.53.155.43
    2025.09.03.673940v1.full-html.html
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    52.53.155.43/b390f332078e676408341ffa6e8b08cc99bc449d/2025.09.03.673940v1.full-html.html
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rag GTPases control lysosomal acidification by regulating v-ATPase assembly in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332402/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-fat diet impairs intermediate-term memory by autophagic-lysosomal dysfunction in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12370196/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impaired mitochondria-initiated crosstalk with lysosomes reciprocally aggravates mitochondrial defect through LManVI
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332152/
  41. Jul 2025
  42. 52.53.155.43 52.53.155.43
    1-s2.0-S092544392500081X-mmc1-html.html
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    52.53.155.43/b979acf386c204c3bb7fba4d3b976b4a429a1667/1-s2.0-S092544392500081X-mmc1-html.html
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppression of autophagic activity by Rubicon is a signature of aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC6381146/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC6613884/
  45. Jun 2025
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of nuclear envelope bud formation leads to mitophagy initiation in Drosophila muscles
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11921965/
  47. May 2025
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Restoring calcium crosstalk between ER and mitochondria promotes intestinal stem cell rejuvenation through autophagy in aged Drosophila
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12116733/
  49. rupress.org rupress.org
    The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B
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    rupress.org/jcb/article/224/5/e202407014/277317/The-deubiquitinase-USP45-inhibits-autophagy
  50. Mar 2025
  51. www.sciencedirect.com www.sciencedirect.com
    PDZD8 promotes autophagy at ER-lysosome membrane contact sites to regulate activity-dependent synaptic growth
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    sciencedirect.com/science/article/pii/S2211124725002542
  52. Feb 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals
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    pmc.ncbi.nlm.nih.gov/articles/PMC5944365/
  54. Dec 2024
  55. 52.53.155.43 52.53.155.43
    OXR1 maintains the retromer to delay brain aging under dietary restriction
    1
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    52.53.155.43/b2d9ae773adaa873dfba750e4f392de3454b4520/41467_2023_Article_44343-html.html
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Atl (atlastin) regulates mTor signaling and autophagy in Drosophila muscle through alteration of the lysosomal network
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC10761077/
  57. Oct 2024
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silver nanoparticles have lethal and sublethal adverse effects on development and longevity by inducing ROS-mediated stress responses
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC5799281/
  59. Aug 2024
  60. www.frontiersin.org www.frontiersin.org
    Codon-optimized TDP-43 mediates neurodegeneration in a Drosophila model of ALS/FTLD
    1
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    frontiersin.org/articles/10.3389/fgene.2023.881638
  61. Jul 2024
  62. www.sciencedirect.com www.sciencedirect.com
    Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration
    2
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    sciencedirect.com/science/article/pii/S1534580724003988
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10136645/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phagocytosis Is the Sole Arm of Drosophila melanogaster Known Host Defenses That Provides Some Protection Against Microsporidia Infection
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9043853/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rescue of lysosomal function as therapeutic strategy for SPG15 hereditary spastic paraplegia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9976989/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of the Mitochondrial Fission GTPase Drp1 Contributes to Neurodegeneration in a Drosophila Model of Hereditary Spastic Paraplegia
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    ncbi.nlm.nih.gov/pmc/articles/PMC7564485/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging
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    ncbi.nlm.nih.gov/pmc/articles/PMC9933915/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau Accumulation via Reduced Autophagy Mediates GGGGCC Repeat Expansion-Induced Neurodegeneration in Drosophila Model of ALS
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7719145/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC7116740/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An intestinal zinc sensor regulates food intake and developmental growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC8833092/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTOR-Dependent Autophagy Regulates Slit Diaphragm Density in Podocyte-like Drosophila Nephrocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9265458/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conserved STRIPAK complex is required for autophagy in muscle tissue
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    ncbi.nlm.nih.gov/pmc/articles/PMC10398890/
  73. 52.53.155.43 52.53.155.43
    PMC10784588-html.html
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    52.53.155.43/0d4f4a1744e053bf921a7c29744fe98d26945d6f/PMC10784588-html.html
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014992/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Drosophila Nesprin-1 homolog MSP300 is required for muscle autophagy and proteostasis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213522/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11192839/
  77. May 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDZD8 promotes autophagy at ER-Lysosome contact sites to regulate synaptogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10634952/
  79. Feb 2024
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811860/
  81. Dec 2023
  82. www.biorxiv.org www.biorxiv.org
    Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint
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    biorxiv.org/content/10.1101/2021.04.21.440825v1
  83. Oct 2023
  84. www.biorxiv.org www.biorxiv.org
    Drosophila Bchs overexpression recapitulates human WDFY3 neurodevelopmental phenotypes with implications for glial cell involvement in altered head circumference
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    biorxiv.org/content/10.1101/2023.10.16.562295v1
  85. www.biorxiv.org www.biorxiv.org
    Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction in C9orf72 ALS/FTD in vivo models and patient iNeurons
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    biorxiv.org/lookup/doi/10.1101/2023.10.02.560439
  86. Aug 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10427020/
  88. Jun 2023
  89. www.sciencedirect.com www.sciencedirect.com
    The RagA GTPase protects young egg chambers in Drosophila
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    sciencedirect.com/science/article/pii/S2211124723006423
  90. May 2023
  91. www.biorxiv.org www.biorxiv.org
    Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
    1
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    biorxiv.org/content/10.1101/2023.05.14.540700v1
  92. Apr 2023
  93. www.sciencedirect.com www.sciencedirect.com
    Bub1 and Bub3 regulate metabolic adaptation via macrolipophagy in Drosophila
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    sciencedirect.com/science/article/pii/S2211124723003546
  94. Jan 2023
  95. www.sciencedirect.com www.sciencedirect.com
    EGFR-dependent suppression of synaptic autophagy is required for neuronal circuit development
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    sciencedirect.com/science/article/pii/S0960982222019765
  96. Nov 2022
  97. movementdisorders.onlinelibrary.wiley.com movementdisorders.onlinelibrary.wiley.com
    Nicotine-Mediated Rescue of α-Synuclein Toxicity Requires Synaptic Vesicle Glycoprotein 2 in Drosophila
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    movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.29283
  98. journals.biologists.com journals.biologists.com
    Formation and function of a highly specialised type of organelle in cardiac valve cells
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    journals.biologists.com/dev/article/149/19/dev200701/276991/Formation-and-function-of-a-highly-specialised
  99. Nov 2021
  100. www.scienceintheclassroom.org www.scienceintheclassroom.org
    Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1
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    scienceintheclassroom.org/research-papers/control-lysosomal-mediated-cell-death-ph-dependent-calcium-channel-recs1
  101. Jul 2021
  102. www.sciencedirect.com www.sciencedirect.com
    Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
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    sciencedirect.com/science/article/pii/S1534580721005165
  103. Jan 2021
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7758070/
  105. Jan 2020
  106. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718319557
  107. Nov 2018
  108. www.sciencedirect.com www.sciencedirect.com
    HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila
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    sciencedirect.com/science/article/pii/S1534580717307141