55 Matching Annotations
  1. Dec 2024
  2. 52.53.155.43 52.53.155.43
    OXR1 maintains the retromer to delay brain aging under dietary restriction
    1
    1. scibot 13 Dec 2024
      43642

      DOI: 10.1038/s41467-023-44343-3

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    52.53.155.43/b2d9ae773adaa873dfba750e4f392de3454b4520/41467_2023_Article_44343-html.html
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mifepristone and rapamycin have non-additive benefits for life span in mated female Drosophila
    1
    1. scibot 21 Nov 2024
      BDSC#43642

      DOI: 10.1080/19336934.2024.2419151

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    pmc.ncbi.nlm.nih.gov/articles/PMC11514543/
  5. Sep 2024
  6. www.biorxiv.org www.biorxiv.org
    Mis-regulation of GSK-3β causes axonal microtubule curling through Shot and Tau
    1
    1. scibot 15 Sep 2024
      RRID:BDSC_43642

      DOI: 10.1101/2024.09.08.611864

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    biorxiv.org/content/10.1101/2024.09.08.611864v1
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration
    1
    1. scibot 13 Sep 2024
      BDSC #43642

      DOI: 10.1038/s41420-023-01643-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10533867/
  8. Aug 2024
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A phosphorylation-deficient mutant of Sik3, a homolog of Sleepy, alters circadian sleep regulation by PDF neurons in Drosophila
    1
    1. scibot 13 Aug 2024
      43642

      DOI: 10.3389/fnins.2023.1181555

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    pmc.ncbi.nlm.nih.gov/articles/PMC10469759/
  10. www.frontiersin.org www.frontiersin.org
    Mifepristone Increases Life Span of Virgin Female Drosophila on Regular and High-fat Diet Without Reducing Food Intake
    1
    1. scibot 02 Aug 2024
      BDSC#43642

      DOI: 10.3389/fgene.2021.751647

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    frontiersin.org/articles/10.3389/fgene.2021.751647
  11. www.frontiersin.org www.frontiersin.org
    Mifepristone Increases Life Span in Female Drosophila Without Detectable Antibacterial Activity
    1
    1. scibot 02 Aug 2024
      BDSC#43642

      DOI: 10.3389/fragi.2022.924957

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    frontiersin.org/articles/10.3389/fragi.2022.924957
  12. Jul 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A neuroendocrine pathway modulating osmotic stress in Drosophila
    1
    1. scibot 27 Jul 2024
      43642

      DOI: 10.1371/journal.pgen.1009425

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    ncbi.nlm.nih.gov/pmc/articles/PMC7971876/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS
    1
    1. scibot 27 Jul 2024
      BDSC

      DOI: 10.1186/s12979-023-00354-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10280928/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An optimized temporally controlled Gal4 system in Drosophila reveals degeneration caused by adult-onset neuronal Vps13D knockdown
    1
    1. scibot 27 Jul 2024
      BL# 43642

      DOI: 10.3389/fnins.2023.1204068

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    ncbi.nlm.nih.gov/pmc/articles/PMC10339317/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The FUS gene is dual‐coding with both proteins contributing to FUS‐mediated toxicity
    1
    1. scibot 26 Jul 2024
      43642

      DOI: 10.15252/embr.202050640

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      RRID:BDSC_43642 DOI:10.15252/embr.202050640
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    ncbi.nlm.nih.gov/pmc/articles/PMC7788448/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons
    1
    1. scibot 25 Jul 2024
      43642

      DOI: 10.1093/hmg/ddab089

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    ncbi.nlm.nih.gov/pmc/articles/PMC8188407/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age
    1
    1. scibot 24 Jul 2024
      43642

      DOI: 10.1038/s42003-023-04822-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10105717/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock
    1
    1. scibot 24 Jul 2024
      BDSC 43642

      DOI: 10.7554/eLife.82364

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    ncbi.nlm.nih.gov/pmc/articles/PMC10110236/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myc suppresses male–male courtship in Drosophila
    1
    1. scibot 23 Jul 2024
      43642

      DOI: 10.15252/embj.2021109905

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    ncbi.nlm.nih.gov/pmc/articles/PMC8982623/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster
    1
    1. scibot 22 Jul 2024
      43642

      DOI: 10.1038/s41467-022-30975-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC9174495/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Roles of ZnT86D in Neurodevelopment and Pathogenesis of Alzheimer Disease in a Drosophila melanogaster Model
    1
    1. scibot 21 Jul 2024
      BL43642

      DOI: 10.3390/ijms231911832

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    ncbi.nlm.nih.gov/pmc/articles/PMC9569493/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control
    1
    1. scibot 20 Jul 2024
      43642

      DOI: 10.1371/journal.pgen.1008727

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    ncbi.nlm.nih.gov/pmc/articles/PMC7205319/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dissecting the Genetic Basis of Variation in Drosophila Sleep Using a Multiparental QTL Mapping Resource
    1
    1. scibot 20 Jul 2024
      43642

      DOI: 10.3390/genes11030294

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      DOI:10.3390/genes11030294 RRID:BDSC_43642
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    ncbi.nlm.nih.gov/pmc/articles/PMC7140804/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response
    1
    1. scibot 20 Jul 2024
      Table

      DOI: 10.1007/s11357-022-00557-9

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      Curator: @mpairish

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    ncbi.nlm.nih.gov/pmc/articles/PMC9616999/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic Signatures of Life Span Regulated by Mating, Sex Peptide, and Mifepristone/RU486 in Female Drosophila melanogaster
    1
    1. scibot 16 Jul 2024
      Supplementary Materials

      DOI: 10.1093/gerona/glaa164

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      Curator: @bpowell22

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      DOI:10.1093/gerona/glaa164 RRID:BDSC_43642
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    ncbi.nlm.nih.gov/pmc/articles/PMC7812429/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GWAS for Lifespan and Decline in Climbing Ability in Flies upon Dietary Restriction Reveal decima as a Mediator of Insulin-like Peptide Production
    1
    1. scibot 16 Jul 2024
      43642

      DOI: 10.1016/j.cub.2020.05.020

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    ncbi.nlm.nih.gov/pmc/articles/PMC7375902/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paternal restraint stress affects offspring metabolism via ATF-2 dependent mechanisms in Drosophila melanogaster germ cells
    1
    1. scibot 15 Jul 2024
      43642

      DOI: 10.1038/s42003-020-0935-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC7198565/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1
    1
    1. scibot 14 Jul 2024
      43642

      DOI: 10.1083/jcb.202103033

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    ncbi.nlm.nih.gov/pmc/articles/PMC8570292/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Effects of poly-GA and poly-PR C9orf72 Dipeptide Repeats on Sleep Patterns in Drosophila melanogaster
    1
    1. scibot 13 Jul 2024
      43642

      DOI: 10.17912/micropub.biology.000973

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      DOI:10.17912/micropub.biology.000973 RRID:BDSC_43642
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    ncbi.nlm.nih.gov/pmc/articles/PMC10943360/
  31. 52.53.155.43 52.53.155.43
    PMC10784588-html.html
    2
    1. scibot 10 Jul 2024
      BDSC:43642

      DOI: 10.1038/s41467-023-44343-3

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    2. scibot 10 Jul 2024
      BDSC:43642

      DOI: 10.1038/s41467-023-44343-3

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    52.53.155.43/0d4f4a1744e053bf921a7c29744fe98d26945d6f/PMC10784588-html.html
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission
    1
    1. scibot 09 Jul 2024
      43642

      DOI: 10.7554/eLife.91927

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    ncbi.nlm.nih.gov/pmc/articles/PMC11060718/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal ageing is promoted by the decay of the microtubule cytoskeleton
    1
    1. scibot 06 Jul 2024
      Bloomington stock 43642

      DOI: 10.1371/journal.pbio.3002504

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      Curator: @DavidDeutsch

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      RRID:BDSC_43642 DOI:10.1371/journal.pbio.3002504
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    ncbi.nlm.nih.gov/pmc/articles/PMC10962844/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sulfated disaccharide protects membrane and DNA damages from arginine-rich dipeptide repeats in ALS
    1
    1. scibot 05 Jul 2024
      43642

      DOI: 10.1126/sciadv.adj0347

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      RRID:BDSC_43642 DOI:10.1126/sciadv.adj0347
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    ncbi.nlm.nih.gov/pmc/articles/PMC10889363/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    dNAGLU Extends Life Span and Promotes Fitness and Stress Resistance in Drosophila
    1
    1. scibot 03 Jul 2024
      43642 flies

      DOI: 10.3390/ijms232214433

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    ncbi.nlm.nih.gov/pmc/articles/PMC9694703/
  36. Jun 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A screen of small molecule and genetic modulators of life span in female Drosophila identifies etomoxir, RH5849 and unanticipated temperature effects
    1
    1. scibot 19 Jun 2024
      (BDSC#43642)

      DOI: 10.1080/19336934.2022.2149209

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      RRID:BDSC_43642 DOI:10.1080/19336934.2022.2149209
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    ncbi.nlm.nih.gov/pmc/articles/PMC9683069/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy
    1
    1. scibot 14 Jun 2024
      BDSC:43642

      DOI: 10.1186/s13024-022-00585-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC9733332/
  39. May 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Upregulation of neuronal ER-phagy improves organismal fitness and alleviates APP toxicity
    1
    1. scibot 21 May 2024
      BDSC:43642

      DOI: 10.1016/j.celrep.2024.114255

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    sciencedirect.com/science/article/pii/S2211124724005837
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tailed mirtron promotes longevity in Drosophila
    1
    1. scibot 07 May 2024
      43642

      DOI: 10.1093/nar/gkad1158

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    ncbi.nlm.nih.gov/pmc/articles/PMC10853799/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD
    1
    1. scibot 07 May 2024
      43642

      DOI: 10.1038/s41467-023-44215-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10728118/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dhr96[1] mutation and maternal tudor[1] mutation increase life span and reduce the beneficial effects of mifepristone in mated female Drosophila
    1
    1. scibot 04 May 2024
      BDSC#43642

      DOI: 10.1371/journal.pone.0292820

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    ncbi.nlm.nih.gov/pmc/articles/PMC10735022/
  44. Apr 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional identity of hypothalamic melanocortin neurons depends on Tbx3
    1
    1. scibot 07 Apr 2024
      BDSC43642

      DOI: 10.1038/s42255-018-0028-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC8291379/
  46. Feb 2024
  47. bmcgenomics.biomedcentral.com bmcgenomics.biomedcentral.com
    The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster
    1
    1. scibot 21 Feb 2024
      43642

      DOI: 10.1186/s12864-020-6739-1

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    bmcgenomics.biomedcentral.com/articles/10.1186/s12864-020-6739-1
  48. link.springer.com link.springer.com
    Simultaneous activation of the hydrogen sulfide biosynthesis genes (CBS and CSE) induces sex-specific geroprotective effects in Drosophila melanogaster
    1
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      43642

      DOI: 10.1007/s10522-023-10017-2

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    link.springer.com/article/10.1007/s10522-023-10017-2
  49. www.biorxiv.org www.biorxiv.org
    Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration
    1
    1. scibot 09 Feb 2024
      BDSC #43642

      DOI: 10.1101/2023.03.14.532519

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

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      RRIDCUR:Missing RRID:BDSC_43642
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    biorxiv.org/content/10.1101/2023.03.14.532519v1
  50. Jan 2024
  51. www.mdpi.com www.mdpi.com
    Neuronal atg1 Coordinates Autophagy Induction and Physiological Adaptations to Balance mTORC1 Signalling
    1
    1. scibot 18 Jan 2024
      BDSC:43642

      DOI: 10.3390/cells12162024

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @Naa003

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      RRID:BDSC_43642 RRIDCUR:SyntaxError RRIDCUR:Unresolved
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    mdpi.com/2073-4409/12/16/2024
  52. Aug 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
    1
    1. scibot 03 Aug 2023
      BDSC:43642

      DOI: 10.7554/eLife.84338

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @evieth

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      RRIDCUR:Unresolved RRID:BDSC_43642
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    ncbi.nlm.nih.gov/pmc/articles/PMC10393046/
  54. Jul 2023
  55. link.springer.com link.springer.com
    A Novel Drosophila-based Drug Repurposing Platform Identified Fingolimod As a Potential Therapeutic for TDP-43 Proteinopathy
    1
    1. scibot 29 Jul 2023
      RRID:BDSC_43642

      DOI: 10.1007/s13311-023-01406-z

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

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      RRID:BDSC_43642
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    link.springer.com/article/10.1007/s13311-023-01406-z
  56. Jun 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo
    1
    1. scibot 22 Jun 2022
      BDSC:43642

      DOI: 10.1016/j.crmeth.2022.100235

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

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      RRID:BDSC_43642
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    sciencedirect.com/science/article/pii/S2667237522001047
  58. Aug 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31
    1
    1. scibot 01 Aug 2021
      BDSC:43642

      DOI: 10.1016/j.neuron.2017.02.046

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @scibot

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      RRID:BDSC_43642
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    sciencedirect.com/science/article/pii/S089662731730154X
  60. Jul 2021
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo imaging reveals mitophagy independence in the maintenance of axonal mitochondria during normal aging
    1
    1. scibot 27 Jul 2021
      43642

      DOI: 10.1111/acel.12654

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @mpairish

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      RRID:BDSC_43642
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    ncbi.nlm.nih.gov/pmc/articles/PMC5595681/
  62. Apr 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Huntingtin-mediated axonal transport requires arginine methylation by PRMT6
    1
    1. scibot 14 Apr 2021
      Cat#43642

      DOI: 10.1016/j.celrep.2021.108980

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @Naa003

      SciCrunch record: RRID:BDSC_43642

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      RRIDCUR:Missing RRID:BDSC_43642
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    sciencedirect.com/science/article/pii/S2211124721002941
  64. Feb 2021
  65. www.cell.com www.cell.com
    Clock neurons gate memory extinction in Drosophila
    1
    1. scibot 24 Feb 2021
      RRID:BDSC_43642

      DOI: 10.1016/j.cub.2021.01.008

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:BDSC_43642
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    cell.com/current-biology/fulltext/S0960-9822(21)00041-5
  66. Sep 2020
  67. www.cell.com www.cell.com
    Long-Term Memory Engram Cells Are Established by c-Fos/CREB Transcriptional Cycling
    1
    1. scibot 04 Sep 2020
      RRID: BDSC_43642

      DOI: 10.1016/j.celrep.2018.11.022

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @evieth

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      RRID:BDSC_43642
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    cell.com/cell-reports/fulltext/S2211-1247(18)31768-6
  68. Aug 2020
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27
    1
    1. scibot 22 Aug 2020
      43,642

      DOI: 10.1111/acel.13179

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @ethanbadger

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    onlinelibrary.wiley.com/doi/10.1111/acel.13179
  70. Jan 2020
  71. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:BDSC_43642

      DOI: 10.1016/j.celrep.2018.11.022

      Resource: (BDSC Cat# 43642,RRID:BDSC_43642)

      Curator: @evieth

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      RRID:BDSC_43642 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124718317686
  72. Nov 2018
  73. www.jneurosci.org www.jneurosci.org
    Drosophila Exo70 Is Essential for Neurite Extension and Survival under Thermal Stress
    1
    1. scibot 05 Nov 2018
      RRID:BDSC_43642

      Curator: @evieth

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      RRID:BDSC_43642

      SciCrunch record: RRID:BDSC_43642

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      RRID:BDSC_43642 RRIDCUR:Validated
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    jneurosci.org/content/38/37/8071
  74. www.sciencedirect.com www.sciencedirect.com
    mHTT Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington’s Disease
    1
    1. scibot 05 Nov 2018
      43642

      Curator: @Jmenke

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      RRID:BDSC_43642

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      RRID:BDSC_43642 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276518306014
  75. Nov 2017
  76. www.sciencedirect.com www.sciencedirect.com
    Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31
    1
    1. scibot 08 Nov 2017
      BDSC:43642

      Curator: @Zeljana_Babic

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      RRID:BDSC_43642

      SciCrunch record: RRID:BDSC_43642

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      RRID:BDSC_43642 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S089662731730154X