50 Matching Annotations
  1. Last 7 days
  2. 54.241.53.176 54.241.53.176
    Genetic analyses enabled by the Fourth Chromosome Resource Projectreveal unexpected mutant phenotypes and suggest new disease models
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    54.241.53.176/a03d21937ee3f0049cfb8dc180bd2b83970a706a/jkag077_supplementary_data-html.html
  3. Jul 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CalDAG-GEFI acts as a guanine nucleotide exchange factor for LRRK2 to regulate LRRK2 function and neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC11584015/
  5. Apr 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11244999/
  7. Mar 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stress granule formation helps to mitigate neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC10659376/
  9. Jan 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calcium waves facilitate and coordinate the contraction of endfeet actin stress fibers in Drosophila interommatidial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC8710306/
  11. Dec 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockdown of PR-DUB subunit calypso in the developing Drosophila eye and wing results in mis-patterned tissues with altered size and shape
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    pmc.ncbi.nlm.nih.gov/articles/PMC12693516/
  13. Nov 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluation of the toxicity and efficacy of a multi-target polymer-drug nano-polyplex in SH-SY5Y cells and Drosophila model of tauopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12606271/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD
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    pmc.ncbi.nlm.nih.gov/articles/PMC7401224/
  16. Sep 2025
  17. 52.53.155.43 52.53.155.43
    2025.09.03.673940v1.full-html.html
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    52.53.155.43/b390f332078e676408341ffa6e8b08cc99bc449d/2025.09.03.673940v1.full-html.html
  18. Aug 2025
  19. 52.53.155.43 52.53.155.43
    Knockdown of PR-DUB subunit calypso in the developing Drosophila eye and wing results in mis-patterned tissues with altered size and shape
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    52.53.155.43/72ed7b795c9e1a47011f00399ae5c24574ef1c6a/2025.01.09.631961v1.full-html.html
  20. www.sciencedirect.com www.sciencedirect.com
    Protocol for a two-clone system to study signaling interactions among neuronal cells in a pre-clinical Alzheimer’s disease model
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    sciencedirect.com/science/article/pii/S2666166725003995
  21. 52.53.155.43 52.53.155.43
    Regulation of polyamine interconversion enzymes affects α-Synuclein levels and toxicity in a Drosophila model of Parkinson’s Disease
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    52.53.155.43/27eb07aa0570ef0126484c8c67b628eefaf115de/s41531-025-01087-9-html.html
  22. 52.53.155.43 52.53.155.43
    pnas.1800677115.st01 (1)-html.html
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    52.53.155.43/152440e327de8c82d5d3f2fb093417e999433359/pnas.1800677115.st01 (1)-html.html
  23. Jul 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability
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    pmc.ncbi.nlm.nih.gov/articles/PMC12213515/
  25. Jun 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regulation of polyamine interconversion enzymes affects α-Synuclein levels and toxicity in a Drosophila model of Parkinson’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12136214/
  27. 52.53.155.43 52.53.155.43
    2025.03.06.641237v1.full-html.html
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    52.53.155.43/c19f41b08c79a3c9a07e241453937058a1535ca3/2025.03.06.641237v1.full-html.html
  28. May 2025
  29. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.70056
  30. Apr 2025
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A phenotypically robust model of spinal and bulbar muscular atrophy in Drosophila
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    onlinelibrary.wiley.com/doi/10.1002/jnr.25278
  32. Feb 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11848802/
  34. Nov 2024
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC16A8 is a causal contributor to age-related macular degeneration risk
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    pmc.ncbi.nlm.nih.gov/articles/PMC11519927/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel peptide‐based tau aggregation inhibitor as a potential therapeutic for Alzheimer's disease and other tauopathies
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    pmc.ncbi.nlm.nih.gov/articles/PMC11567856/
  37. Sep 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    dTBC1D7 regulates systemic growth independently of TSC through insulin signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5800808/
  39. Aug 2024
  40. www.molbiolcell.org www.molbiolcell.org
    Stratum is required for both apical and basolateral transport through stable expression of Rab10 and Rab35 in Drosophila photoreceptors
    1
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    molbiolcell.org/doi/10.1091/mbc.E21-12-0596
  41. www.frontiersin.org www.frontiersin.org
    Frontiers | Ubiquitin-binding site 1 of pathogenic ataxin-3 regulates its toxicity in Drosophila models of Spinocerebellar Ataxia Type 3
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    frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2022.1112688/full
  42. Jul 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sec71 separates Golgi stacks in Drosophila S2 cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10668125/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proper control of R‐loop homeostasis is required for maintenance of gene expression and neuronal function during aging
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    ncbi.nlm.nih.gov/pmc/articles/PMC8844117/
  45. www.molbiolcell.org www.molbiolcell.org
    Stratum is required for both apical and basolateral transport through stable expression of Rab10 and Rab35 in Drosophila photoreceptors
    1
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    molbiolcell.org/doi/10.1091/mbc.E21-12-0596
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual functions of Rack1 in regulating Hedgehog pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC7560836/
  47. academic.oup.com academic.oup.com
    Non-canonical initiation factors modulate repeat-associated non-AUG translation
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    academic.oup.com/hmg/article/31/15/2521/6528265
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinctive alteration in the expression of autophagy genes in Drosophila models of amyloidopathy and tauopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC7594860/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX3X and specific initiation factors modulate FMR1 repeat‐associated non‐AUG‐initiated translation
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    ncbi.nlm.nih.gov/pmc/articles/PMC6726903/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Druggable genome screen identifies new regulators of the abundance and toxicity of ATXN3, the Spinocerebellar Ataxia Type 3 disease protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7050396/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phenotypic defects from the expression of wild-type and pathogenic TATA-binding proteins in new Drosophila models of Spinocerebellar Ataxia Type 17
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    ncbi.nlm.nih.gov/pmc/articles/PMC10542169/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional dysregulation by a nucleus-localized aminoacyl-tRNA synthetase associated with Charcot-Marie-Tooth neuropathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC6834567/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Acetyltransferase 9 ameliorates Aβ42-mediated neurodegeneration in the Drosophila eye
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    ncbi.nlm.nih.gov/pmc/articles/PMC10382493/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A drug stabilizable GAL80ds for conditional control of gene expression via GAL4-UAS and CRISPR-Cas9 systems in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10928143/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sidekick Is a Key Component of Tricellular Adherens Junctions that Acts to Resolve Cell Rearrangements
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    ncbi.nlm.nih.gov/pmc/articles/PMC6748646/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of mutant CHMP2B linked to neurodegeneration in humans disrupts circadian rhythms in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC6996329/
  57. Jun 2024
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALS-Associated KIF5A Mutation Causes Locomotor Deficits Associated with Cytoplasmic Inclusions, Alterations of Neuromuscular Junctions, and Motor Neuron Loss
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    ncbi.nlm.nih.gov/pmc/articles/PMC10669773/
  59. Feb 2024
  60. www.biorxiv.org www.biorxiv.org
    Age and dose-dependent effects of alpha-lipoic acid on human microtubule-associated protein tau-induced endoplasmic reticulum unfolded protein response: implications for Alzheimer’s disease
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    biorxiv.org/content/10.1101/2020.07.31.230847v1
  61. www.sciencedirect.com www.sciencedirect.com
    Complex formation of immunoglobulin superfamily molecules Side-IV and Beat-IIb regulates synaptic specificity
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    sciencedirect.com/science/article/pii/S2211124724001268
  62. Feb 2023
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10166451/
  64. Feb 2022
  65. www.sciencedirect.com www.sciencedirect.com
    Protocol to study cell death using TUNEL assay in Drosophila imaginal discs
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    sciencedirect.com/science/article/pii/S266616672200020X
  66. Jun 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R7 photoreceptor axon targeting depends on the relative levels of lost and found expression in R7 and its synaptic partners
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    ncbi.nlm.nih.gov/pmc/articles/PMC8205486/
  68. May 2021
  69. www.sciencedirect.com www.sciencedirect.com
    The Distinctive Role of Tau and Amyloid beta in Mitochondrial Dysfunction through Alteration in Mfn2 and Drp1 mRNA Levels: A Comparative Study in Drosophila melanogaster
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    sciencedirect.com/science/article/pii/S0378111920305230
  70. Mar 2021
  71. www.sciencedirect.com www.sciencedirect.com
    DNT1 Downregulation and Increased Ethanol Sensitivity in Transgenic Drosophila Models of Alzheimer's Disease
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    sciencedirect.com/science/article/pii/S0167494321000182
  72. Sep 2020
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conserved, N-terminal tyrosine signal directs Ras for inhibition by Rabex-5
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    ncbi.nlm.nih.gov/pmc/articles/PMC7329146/
  74. Jan 2020
  75. www.sciencedirect.com www.sciencedirect.com
    MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network
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    sciencedirect.com/science/article/pii/S1097276519301029
  76. Nov 2018
  77. www.sciencedirect.com www.sciencedirect.com
    The WAVE Regulatory Complex and Branched F-Actin Counterbalance Contractile Force to Control Cell Shape and Packing in the Drosophila Eye
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    sciencedirect.com/science/article/pii/S1534580717310420