162 Matching Annotations
  1. Apr 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TMBIM6 enhances dopaminergic neuron survival by modulating the IRE1a pathway in Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13061952/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042358/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disease-causing mutations in Synaptotagmin can act via dominant-negative, gain-of-function or haploinsufficient mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC13015553/
  5. www.biorxiv.org www.biorxiv.org
    ZDHHC17 Links S-Acylation, Huntington Disease, VCP-associated Multisystem Proteinopathy, and Amyotrophic Lateral Sclerosis
    1
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    biorxiv.org/content/10.64898/2026.04.05.716148v1
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PGC-1α integrates insulin signaling with mitochondrial physiology and behavior in a Drosophila model of Fragile X Syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11090494/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Design and Implementation of an Automated Drosophila Locomotor Assay Using Computer Vision Tracking
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    pmc.ncbi.nlm.nih.gov/articles/PMC12919220/
  8. Mar 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Receptors underlying an odorant's valence across concentrations in Drosophila larvae
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    pmc.ncbi.nlm.nih.gov/articles/PMC11166451/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inter-plane feedback coordinates cell morphogenesis and maintains 3D tissue organization in the Drosophila pupal retina
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    pmc.ncbi.nlm.nih.gov/articles/PMC11006395/
  11. 54.241.53.176 54.241.53.176
    UQCRC1 deficiency impairs mitophagy via PINK1-dependent mechanisms in Parkinson’s disease
    1
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    54.241.53.176/b022304cfd6b2287b8842766320f7cd2adc4420a/PMID_41540037-html.html
  12. Feb 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ADAM17‐triggered TNF signalling protects the ageing Drosophila retina from lipid droplet‐mediated degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC7459420/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heterozygous loss of SRRM1 may be associated with neurodevelopmental phenotypes and anomalies in cell growth and neurite morphology
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12858978/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The neurodevelopmental transcriptome of the Drosophila melanogaster microcephaly gene abnormal spindle reveals a role for temporal transcription factors and the immune system in regulating brain size
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC9882087/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated serotonin receptor 2A signaling restores learning and memory in a Fragile X syndrome model
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12864886/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An insecticide target in mechanoreceptor neurons
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC9683716/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC9374236/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endocrine modulation of primary chemosensory neurons regulates Drosophila courtship behavior
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC9439213/
  20. Jan 2026
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockdown of a Cyclic Nucleotide-Gated Ion Channel Impairs Locomotor Activity and Recovery From Hypoxia in Adult Drosophila melanogaster
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC9075734/
  22. 54.241.53.176 54.241.53.176
    ut0001-10.1080_15548627.2025.2541384-html.html
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    54.241.53.176/16a695ee84093c1724cfce6cd200a12993ff63d8/ut0001-10.1080_15548627.2025.2541384-html.html
  23. www.sciencedirect.com www.sciencedirect.com
    Loss and gain of motor protein function cause microtubule bundle damage in Drosophila axons
    1
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    sciencedirect.com/science/article/pii/S0960982225016914
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The cell autonomous and non-autonomous functions of Rab27 in longevity and neuroprotection in Drosophila
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12758210/
  25. www.biorxiv.org www.biorxiv.org
    An Application for Automated Drosophila Locomotor Assay with Integrated Device Design and Computer Vision Tracking
    1
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    biorxiv.org/content/10.1101/2025.10.31.685789v1
  26. Dec 2025
  27. 54.241.53.176 54.241.53.176
    Fer3 is uniquely expressed in NotchOFF hemilineages, where it promotes interneuron identity
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    54.241.53.176/30347be10d56ad746eedda3049f694422ebb0d88/PMID_41122815-html.html
  28. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    X chromosome dosage in respiratory stem cells is critical for post-embryonic development and survival
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    sciencedirect.com:5037/science/article/pii/S0960982225016070
  29. 54.241.53.176 54.241.53.176
    PMID_34085929-html.html
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    54.241.53.176/79eded9f15d9fd63f6a21b008d7c0b526be0ce50/PMID_34085929-html.html
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A fly model of SCA36 reveals combinatorial neurotoxicity of hexanucleotide and dipeptide repeats
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12674567/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC8254809/
  32. Nov 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Masculinized Drosophila females adapt their fighting strategies to their opponent
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC8015213/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC7583931/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Rescue Memory Defects in Drosophila-Expressing Alzheimer’s Disease-Related Transgenes Independently of the Canonical Renin Angiotensin System
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    pmc.ncbi.nlm.nih.gov/articles/PMC7768280/
  36. Oct 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic basis of maneb-induced dopaminergic neurodegeneration in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405872/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impacts of mitochondrial dysfunction on axonal microtubule bundles as a potential mechanism of neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402001/
  39. www.sciencedirect.com www.sciencedirect.com
    Tension transmission across a supracellular network drives increased tissue rigidity in the Drosophila retina
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    sciencedirect.com/science/article/pii/S221112472501126X
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The tanning hormone, bursicon, does not act directly on the epidermis to tan the Drosophila exoskeleton
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC7029472/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PI3K activation prevents Aβ42-induced synapse loss and favors insoluble amyloid deposit formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC7183762/
  42. Sep 2025
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pleiotropic role of Drosophila phosphoribosyl pyrophosphate synthetase in autophagy and lysosome homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC6748441/
  44. Aug 2025
  45. link.springer.com link.springer.com
    Dissecting metabolic regulation of behaviors and physiology during aging in Drosophila
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    link.springer.com/article/10.1007/s10522-025-10306-y
  46. www.sciencedirect.com www.sciencedirect.com
    dArc1 controls sugar reward valuation in Drosophila melanogaster
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    sciencedirect.com/science/article/pii/S0960982225009571
  47. Jul 2025
  48. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/bc4e33e250ccc7c26a8372ad4491fbafeca15953/1-s2.0-S2666247725000284-main-html.html
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single pair of leucokinin neurons are modulated by feeding state and regulate sleep–metabolism interactions
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC6391015/
  50. Jun 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Role of miRNAs in Drosophila melanogaster Male Courtship Behavior
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    pmc.ncbi.nlm.nih.gov/articles/PMC6404249/
  52. 52.53.155.43 52.53.155.43
    Dronc-independent basal executioner caspase activity sustains Drosophila imaginal tissue growth
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    52.53.155.43/dbf51c4ab47e203d9fa2c36368c1ae94ef720c16/elife-99650-supp3-html.html
  53. www.sciencedirect.com www.sciencedirect.com
    Substrate reduction using a glucosamine analogue in Drosophila melanogaster and mouse models of Sanfilippo syndrome
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    sciencedirect.com/science/article/pii/S1096719225001039
  54. 52.53.155.43 52.53.155.43
    2025.05.15.25327061v1.full-html.html
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    52.53.155.43/5405350ddff68aa8209e7b03a47d62f4e41717ba/2025.05.15.25327061v1.full-html.html
  55. 52.53.155.43 52.53.155.43
    2025.02.18.638929v2.full-html.html
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    52.53.155.43/e9bd751e9086c1461462690ec447f3d4b1c0a868/2025.02.18.638929v2.full-html.html
  56. www.sciencedirect.com www.sciencedirect.com
    Quantitative and site-specific chemoproteomic profiling of O-GlcNAcylation in Drosophila
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    sciencedirect.com/science/article/pii/S0968089625001324
  57. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial fumarate inhibits Parkin-mediated mitophagy
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    sciencedirect.com/science/article/pii/S1097276525004605
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLK is mutated in individuals with a neurodevelopmental disorder
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139437/
  59. May 2025
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Two distinct mechanisms of Plexin A function in Drosophila optic lobe lamination and morphogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11190435/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Arsenic impairs Drosophila neural stem cell mitotic progression and sleep behavior in a tauopathy model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12060243/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dysfunctional BCAA degradation triggers neuronal damage through disrupted AMPK-mitochondrial axis due to enhanced PP2Ac interaction
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    pmc.ncbi.nlm.nih.gov/articles/PMC11751115/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-Specific Profiling of O-GlcNAcylated Proteins in Drosophila Using TurboID-CpOGAM
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    pmc.ncbi.nlm.nih.gov/articles/PMC11896768/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ca2+ excitability of glia to neuromodulator octopamine in Drosophila living brain is greater than that of neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11726276/
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin
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    pmc.ncbi.nlm.nih.gov/articles/PMC11742450/
  66. Apr 2025
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Midgut-derived neuropeptide F controls germline stem cell proliferation in a mating-dependent manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC6152996/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Postsynaptic Syntaxin 4 negatively regulates the efficiency of neurotransmitter release
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    pmc.ncbi.nlm.nih.gov/articles/PMC6317344/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Specification of Drosophila neuropeptidergic neurons by the splicing component brr2
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    pmc.ncbi.nlm.nih.gov/articles/PMC6122834/
  70. Mar 2025
  71. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/bc4e33e250ccc7c26a8372ad4491fbafeca15953/1-s2.0-S2666247725000284-main-html.html
  72. Dec 2024
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss-of-function in RBBP5 results in a syndromic neurodevelopmental disorder associated with microcephaly
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    pmc.ncbi.nlm.nih.gov/articles/PMC11648989/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rescuable sleep and synaptogenesis phenotypes in a Drosophila model of O-GlcNAc transferase intellectual disability
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    pmc.ncbi.nlm.nih.gov/articles/PMC11623933/
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3
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    pmc.ncbi.nlm.nih.gov/articles/PMC10806447/
  76. Nov 2024
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De Novo Variants in MRTFB have gain of function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features
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    pmc.ncbi.nlm.nih.gov/articles/PMC11533975/
  78. Oct 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Experience-dependent serotonergic signaling in glia regulates targeted synapse elimination
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    ncbi.nlm.nih.gov/pmc/articles/PMC11444420/
  80. elifesciences.org elifesciences.org
    A sleep state in Drosophila larvae required for neural stem cell proliferation
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    elifesciences.org/articles/33220
  81. Sep 2024
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster
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    ncbi.nlm.nih.gov/pmc/articles/PMC11408159/
  83. Aug 2024
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arsenic impairs Drosophila neural stem cell mitotic progression and sleep behavior in a tauopathy model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11326188/
  85. www.sciencedirect.com www.sciencedirect.com
    The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy
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    sciencedirect.com/science/article/pii/S2211124724008787
  86. 52.53.155.43 52.53.155.43
    42003_2023_5660_MOESM1_ESM-html.html
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    52.53.155.43/f2c92c8a57f6bf77eec54de78b75937be5d446e9/42003_2023_5660_MOESM1_ESM-html.html
  87. 52.53.155.43 52.53.155.43
    PMC7392683 12915_2020_817_MOESM1_ESM-html.html
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    52.53.155.43/0a4dd1c9ae1e30769296954f8bff33724c34d22a/PMC7392683 12915_2020_817_MOESM1_ESM-html.html
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kismet/CHD7/CHD8 and Amyloid Precursor Protein-like Regulate Synaptic Levels of Rab11 at the Drosophila Neuromuscular Junction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11313043/
  89. Jul 2024
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dietary Macronutrient Imbalances Lead to Compensatory Changes in Peripheral Taste via Independent Signaling Pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC8672697/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Dissection of DAAM Function during Axon Growth in Drosophila Embryonic Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9102401/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of the extracellular matrix protein Perlecan disrupts axonal and synaptic stability during Drosophila development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328508/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7935873/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bi-allelic loss-of-function variants in BCAS3 cause a syndromic neurodevelopmental disorder
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    ncbi.nlm.nih.gov/pmc/articles/PMC8206390/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8522249/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New submission 03/11/2023, 09:11:50
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    ncbi.nlm.nih.gov/pmc/articles/PMC10371176/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The fly homolog of SUPT16H, a gene associated with neurodevelopmental disorders, is required in a cell-autonomous fashion for cell survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC9991001/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunoprecipitation for Protein-Protein Interactions and for RNA Enrichment in Drosophila melanogaster
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    ncbi.nlm.nih.gov/pmc/articles/PMC8678549/
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential activation of Notch and Grainyhead gives apoptotic competence to Abdominal-B expressing larval neuroblasts in Drosophila Central nervous system
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    ncbi.nlm.nih.gov/pmc/articles/PMC7485976/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    orsai, the Drosophila homolog of human ETFRF1, links lipid catabolism to growth control
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    ncbi.nlm.nih.gov/pmc/articles/PMC9585818/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC7224696/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Octopamine signaling via OctαR is essential for a well-orchestrated climbing performance of adult Drosophila melanogaster
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  132. Jun 2024
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  136. May 2024
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  142. Apr 2024
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  144. Feb 2024
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  151. Jan 2024
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  159. Dec 2023
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  162. Aug 2023
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  164. Mar 2023
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  166. Nov 2022
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  168. May 2022
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  170. Sep 2021
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  173. Aug 2021
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  177. Jul 2021
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  180. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
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  181. May 2021
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  183. Apr 2021
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  185. Mar 2021
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  188. Feb 2021
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  190. Nov 2020
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  192. Sep 2020
  193. f1000research.com f1000research.com
    A miRNA screen procedure identifies <i>garz</i> as an essential factor in adult glia functions and validates <i>Drosophila</i> as a beneficial 3Rs model to study glial functions and GBF1 biology
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  194. Jan 2020
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  196. Nov 2018
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  200. Nov 2017
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    The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D
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