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Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity

1
1. scibot 03 Apr 2025
  
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  8816
  
  DOI: 10.1016/j.celrep.2018.06.070
  
  Resource: RRID:BDSC_8816
  
  Curator: @bdscstockkeepers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6077250/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Drosophila Ubiquitin C-Terminal Hydrolase Knockdown Model of Parkinson’s Disease

1
1. scibot 26 Feb 2025
  
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  Bloomington #8816
  
  DOI: 10.1038/s41598-018-22804-w
  
  Resource: RRID:BDSC_8816
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5849740/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Examining the potential involvement of NONO in TDP‐43 proteinopathy in Drosophila

1
1. scibot 24 Jan 2025
  
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  RRID:BDSC_8816
  
  DOI: 10.1111/ejn.16632
  
  Resource: RRID:BDSC_8816
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11670437/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects

1
1. scibot 10 Dec 2024
  
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  8816
  
  DOI: 10.1002/ana.25220
  
  Resource: RRID:BDSC_8816
  
  Curator: @dawnn.marie
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6105379/
Aug 2024
www.frontiersin.org www.frontiersin.org

Glutamatergic Synapse Dysfunction in Drosophila Neuromuscular Junctions Can Be Rescued by Proteostasis Modulation

1
1. scibot 02 Aug 2024
  
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  8816
  
  DOI: 10.3389/fnmol.2022.842772
  
  Resource: RRID:BDSC_8816
  
  Curator: @Naa003
  
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frontiersin.org/articles/10.3389/fnmol.2022.842772
www.tandfonline.com www.tandfonline.com

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

1
1. scibot 02 Aug 2024
  
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  BDSC: 8816
  
  DOI: 10.1080/15548627.2019.1596477
  
  Resource: RRID:BDSC_8816
  
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tandfonline.com/doi/full/10.1080/15548627.2019.1596477
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetic Targeting of dSAMTOR, A Negative dTORC1 Regulator, during Drosophila Aging: A Tissue-Specific Pathology

1
1. scibot 27 Jul 2024
  
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  8816
  
  DOI: 10.3390/ijms24119676
  
  Resource: RRID:BDSC_8816
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10253371/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PINK1 and Parkin Ameliorate the Loss of Motor Activity and Mitochondrial Dysfunction Induced by Peripheral Neuropathy-Associated HSPB8 Mutants in Drosophila Models

1
1. scibot 26 Jul 2024
  
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  BDSC_8816
  
  DOI: 10.3390/biomedicines11030832
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10045361/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons

1
1. scibot 25 Jul 2024
  
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  8816
  
  DOI: 10.1093/hmg/ddab089
  
  Resource: RRID:BDSC_8816
  
  Curator: @anisehay
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8188407/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Insulin signaling mediates neurodegeneration in glioma

1
1. scibot 25 Jul 2024
  
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  8816
  
  DOI: 10.26508/lsa.202000693
  
  Resource: RRID:BDSC_8816
  
  Curator: @mpairish
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7898663/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bi-allelic loss-of-function variants in BCAS3 cause a syndromic neurodevelopmental disorder

1
1. scibot 25 Jul 2024
  
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  BDSC #8816
  
  DOI: 10.1016/j.ajhg.2021.04.024
  
  Resource: RRID:BDSC_8816
  
  Curator: @anisehay
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8206390/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a Drosophila Model of Amyotrophic Lateral Sclerosis

1
1. scibot 24 Jul 2024
  
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  8816
  
  DOI: 10.3390/cells12172163
  
  Resource: RRID:BDSC_8816
  
  Curator: @bandrow
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10486503/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Octopamine signaling via OctαR is essential for a well-orchestrated climbing performance of adult Drosophila melanogaster

1
1. scibot 19 Jul 2024
  
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  8816
  
  DOI: 10.1038/s41598-022-18203-x
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @mpairish
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9388497/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Botulinum neurotoxin accurately separates tonic vs. phasic transmission and reveals heterosynaptic plasticity rules in Drosophila

1
1. scibot 19 Jul 2024
  
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  8816
  
  DOI: 10.7554/eLife.77924
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @mpairish
  
  SciCrunch record: RRID:BDSC_8816
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9439677/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The auxiliary glutamate receptor subunit dSol-1 promotes presynaptic neurotransmitter release and homeostatic potentiation

1
1. scibot 18 Jul 2024
  
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  https://www.pnas.org/lookup/suppl/doi:10.1073/pnas.1915464117/-/DCSupplemental.
  
  DOI: 10.1073/pnas.1915464117
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @bpowell22
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7568321/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Small heat shock proteins determine synapse number and neuronal activity during development

1
1. scibot 16 Jul 2024
  
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  BL-8816
  
  DOI: 10.1371/journal.pone.0233231
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @bpowell22
  
  SciCrunch record: RRID:BDSC_8816
  
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  RRID:BDSC_8816 DOI:10.1371/journal.pone.0233231
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DOI:10.1371/journal.pone.0233231

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ncbi.nlm.nih.gov/pmc/articles/PMC7241713/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function

1
1. scibot 15 Jul 2024
  
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  8816
  
  DOI: 10.1016/j.isci.2021.102899
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @olekpark
  
  SciCrunch record: RRID:BDSC_8816
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8358705/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ATP-citrate lyase promotes axonal transport across species

1
1. scibot 14 Jul 2024
  
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  8816
  
  DOI: 10.1038/s41467-021-25786-y
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @olekpark
  
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  RRID:BDSC_8816
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ncbi.nlm.nih.gov/pmc/articles/PMC8497606/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure and function

1
1. scibot 13 Jul 2024
  
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  8816
  
  DOI: 10.1371/journal.pone.0221006
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @bpowell22
  
  SciCrunch record: RRID:BDSC_8816
  
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  RRID:BDSC_8816
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ncbi.nlm.nih.gov/pmc/articles/PMC7080231/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RNAi of Complex I and V of the electron transport chain in glutamate neurons extends life span, increases sleep, and decreases locomotor activity in Drosophila melanogaster

1
1. scibot 13 Jul 2024
  
  in Public
  
  8816
  
  DOI: 10.1371/journal.pone.0286828
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @olekpark
  
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  DOI:10.1371/journal.pone.0286828 RRID:BDSC_8816
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DOI:10.1371/journal.pone.0286828

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ncbi.nlm.nih.gov/pmc/articles/PMC10270625/
52.53.155.43 52.53.155.43

Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate

1
1. scibot 13 Jul 2024
  
  in Public
  
  BDSC 8816
  
  DOI: 10.1083/jcb.201904148
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @anisehay
  
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  RRID:BDSC_8816
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52.53.155.43/8367afa0072963dd46d57c10d39ab722075d61c7/JCB_201904148_sm-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding

1
1. scibot 13 Jul 2024
  
  in Public
  
  RRID:BDSC_8816
  
  DOI: 10.7554/eLife.52009
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7021487/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A novel in‐frame deletion in KIF5C gene causes infantile onset epilepsy and psychomotor retardation

1
1. scibot 10 Jul 2024
  
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  8816
  
  DOI: 10.1002/mco2.469
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @bandrow
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10960728/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration

1
1. scibot 09 Jul 2024
  
  in Public
  
  BL8816
  
  DOI: 10.1371/journal.pbio.3000545
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @bpowell22
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6917273/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The CHD Protein Kismet Restricts the Synaptic Localization of Cell Adhesion Molecules at the Drosophila Neuromuscular Junction

1
1. scibot 06 Jul 2024
  
  in Public
  
  RRID:BDSC_8816
  
  DOI: 10.3390/ijms25053074
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @DavidDeutsch
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10931923/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport

1
1. scibot 05 Jul 2024
  
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  8816
  
  DOI: 10.1007/s00401-024-02689-y
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @mpairish
  
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  DOI:10.1007/s00401-024-02689-y RRID:BDSC_8816
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DOI:10.1007/s00401-024-02689-y

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ncbi.nlm.nih.gov/pmc/articles/PMC10873455/
May 2024
academic.oup.com academic.oup.com

Humanized Drosophila Model of the Meier-Gorlin Syndrome Reveals Conserved and Divergent Features of the Orc6 Protein

2
1. scibot 15 May 2024
  
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  8816
  
  DOI: 10.1534/genetics.120.303698
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @evieth
  
  SciCrunch record: RRID:BDSC_8816
  
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  RRID:BDSC_8816 DOI:10.1534/genetics.120.303698
2. scibot 15 May 2024
  
  in Public
  
  8816
  
  DOI: 10.1534/genetics.120.303698
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @Naa003
  
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  RRID:BDSC_8816 RRIDCUR:Missing
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DOI:10.1534/genetics.120.303698

RRIDCUR:Missing

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academic.oup.com/genetics/article/216/4/995/6065819
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Simplified homology-assisted CRISPR for gene editing in Drosophila

1
1. scibot 07 May 2024
  
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  8816
  
  DOI: 10.1093/g3journal/jkad277
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @maulamb
  
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  RRID:BDSC_8816
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ncbi.nlm.nih.gov/pmc/articles/PMC10849607/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The CHD family chromatin remodeling enzyme, Kismet, promotes both clathrin-mediated and activity-dependent bulk endocytosis

1
1. scibot 23 Mar 2024
  
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  RRID:BDSC_8816
  
  DOI: 10.1371/journal.pone.0300255
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10956772/
Feb 2024
www.science.org www.science.org

ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

1
1. scibot 13 Feb 2024
  
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  BDSC 8816
  
  DOI: 10.1126/sciadv.aax2705
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @Naa003
  
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  RRID:BDSC_8816 RRIDCUR:Missing
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science.org/doi/10.1126/sciadv.aax2705
www.nature.com www.nature.com

CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum

1
1. scibot 10 Feb 2024
  
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  8816
  
  DOI: 10.1038/s41436-019-0585-z
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:BDSC_8816
  
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  RRIDCUR:Missing RRID:BDSC_8816
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nature.com/articles/s41436-019-0585-z
journals.plos.org journals.plos.org

Hyperpolarization by activation of halorhodopsin results in enhanced synaptic transmission: Neuromuscular junction and CNS circuit

1
1. scibot 09 Feb 2024
  
  in Public
  
  BDSC # 8816
  
  DOI: 10.1371/journal.pone.0200107
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:BDSC_8816
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journals.plos.org/plosone/article
www.biorxiv.org www.biorxiv.org

Examining the potential involvement of NONO in TDP-43 proteinopathy in Drosophila

1
1. scibot 09 Feb 2024
  
  in Public
  
  RRID:BDSC_8816
  
  DOI: 10.1101/2023.12.13.571416
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @scibot
  
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  RRID:BDSC_8816
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biorxiv.org/content/10.1101/2023.12.13.571416v1
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster

1
1. scibot 28 Jan 2024
  
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  8816
  
  DOI: 10.1016/j.neulet.2018.12.009
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @Naa003
  
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  RRID:BDSC_8816 RRIDCUR:Missing
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sciencedirect.com/science/article/abs/pii/S0304394018308553
journals.plos.org journals.plos.org

A comparison of three different methods of eliciting rapid activity-dependent synaptic plasticity at the Drosophila NMJ

1
1. scibot 17 Jan 2024
  
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  BDSC stock #8816
  
  DOI: 10.1371/journal.pone.0260553
  
  Resource: (BDSC Cat# 8816,RRID:BDSC_8816)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:BDSC_8816
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journals.plos.org/plosone/article
Oct 2023
www.science.org www.science.org

Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import

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  DOI: 10.1126/sciadv.adi5548
  
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Jul 2023
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A Novel Drosophila-based Drug Repurposing Platform Identified Fingolimod As a Potential Therapeutic for TDP-43 Proteinopathy

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  DOI: 10.1007/s13311-023-01406-z
  
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link.springer.com/article/10.1007/s13311-023-01406-z
Nov 2022
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Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila

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1. scibot 22 Nov 2022
  
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  RRID: BDSC _8816
  
  DOI: 10.1016/j.isci.2022.105476
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9672966/
Mar 2022
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Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models

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1. scibot 26 Mar 2022
  
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sciencedirect.com/science/article/pii/S1534580722001241
Dec 2021
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Distinct molecular pathways govern presynaptic homeostatic plasticity

1
1. scibot 15 Dec 2021
  
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Macros to Quantify Exosome Release and Autophagy at the Neuromuscular Junction of Drosophila Melanogaster

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1. scibot 04 Dec 2021
  
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  DOI: 10.3389/fcell.2021.773861
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8634598/
Aug 2021
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Untitled document

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1. scibot 13 Aug 2021
  
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  DOI: 10.1016/j.neuron.2017.07.038
  
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SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis

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1. scibot 12 Aug 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8353793/
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Ethanol stimulates the in vivo axonal movement of neuropeptide dense‐core vesicles in Drosophila motor neurons

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1. scibot 02 Aug 2021
  
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  DOI: 10.1111/jnc.14230
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14230
Jul 2021
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C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in Drosophila Glutamatergic Neurons

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1. scibot 28 Jul 2021
  
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  DOI: 10.1523/JNEUROSCI.0908-18.2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6705968/
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Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT

2
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RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology

1
1. scibot 27 Jul 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5499113/
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USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin

1
1. scibot 27 Jul 2021
  
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  DOI: 10.7554/eLife.26886
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5438252/
May 2021
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Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation

1
1. scibot 07 May 2021
  
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  DOI: 10.1016/j.molcel.2020.06.019
  
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sciencedirect.com/science/article/pii/S1097276520304214
Feb 2021
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Identification of FoxP circuits involved in locomotion and object fixation in Drosophila

1
1. scibot 27 Feb 2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7776582/
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Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3

1
1. scibot 27 Feb 2021
  
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  DOI: 10.7554/eLife.60132
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7748415/
Sep 2020
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Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding

1
1. scibot 06 Sep 2020
  
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  DOI: 10.7554/eLife.52009
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7021487/
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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jneurosci.org/content/38/35/7741
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Hsp90 Mediates Membrane Deformation and Exosome Release

1
1. scibot 05 Nov 2018
  
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  BDSC:8816
  
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sciencedirect.com/science/article/pii/S1097276518305859
Nov 2017
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Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration

1
1. scibot 08 Nov 2017
  
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The Spacing Effect for Structural Synaptic Plasticity Provides Specificity and Precision in Plastic Changes

1
1. scibot 08 Nov 2017
  
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  BDSC_8816
  
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Intra-neuronal Competition for Synaptic Partners Conserves the Amount of Dendritic Building Material

1
1. scibot 08 Nov 2017
  
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  BDSC_8816
  
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