59 Matching Annotations
  1. Feb 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila Ubiquitin C-Terminal Hydrolase Knockdown Model of Parkinson’s Disease
    1
    1. scibot 26 Feb 2025
      Bloomington #8816

      DOI: 10.1038/s41598-018-22804-w

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    pmc.ncbi.nlm.nih.gov/articles/PMC5849740/
  3. Jan 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Examining the potential involvement of NONO in TDP‐43 proteinopathy in Drosophila
    1
    1. scibot 24 Jan 2025
      RRID:BDSC_8816

      DOI: 10.1111/ejn.16632

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    pmc.ncbi.nlm.nih.gov/articles/PMC11670437/
  5. Dec 2024
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects
    1
    1. scibot 10 Dec 2024
      8816

      DOI: 10.1002/ana.25220

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    pmc.ncbi.nlm.nih.gov/articles/PMC6105379/
  7. Aug 2024
  8. www.frontiersin.org www.frontiersin.org
    Glutamatergic Synapse Dysfunction in Drosophila Neuromuscular Junctions Can Be Rescued by Proteostasis Modulation
    1
    1. scibot 02 Aug 2024
      8816

      DOI: 10.3389/fnmol.2022.842772

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    frontiersin.org/articles/10.3389/fnmol.2022.842772
  9. www.tandfonline.com www.tandfonline.com
    Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy
    1
    1. scibot 02 Aug 2024
      BDSC: 8816

      DOI: 10.1080/15548627.2019.1596477

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    tandfonline.com/doi/full/10.1080/15548627.2019.1596477
  10. Jul 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Targeting of dSAMTOR, A Negative dTORC1 Regulator, during Drosophila Aging: A Tissue-Specific Pathology
    1
    1. scibot 27 Jul 2024
      8816

      DOI: 10.3390/ijms24119676

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    ncbi.nlm.nih.gov/pmc/articles/PMC10253371/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PINK1 and Parkin Ameliorate the Loss of Motor Activity and Mitochondrial Dysfunction Induced by Peripheral Neuropathy-Associated HSPB8 Mutants in Drosophila Models
    1
    1. scibot 26 Jul 2024
      BDSC_8816

      DOI: 10.3390/biomedicines11030832

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    ncbi.nlm.nih.gov/pmc/articles/PMC10045361/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons
    1
    1. scibot 25 Jul 2024
      8816

      DOI: 10.1093/hmg/ddab089

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    ncbi.nlm.nih.gov/pmc/articles/PMC8188407/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin signaling mediates neurodegeneration in glioma
    1
    1. scibot 25 Jul 2024
      8816

      DOI: 10.26508/lsa.202000693

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    ncbi.nlm.nih.gov/pmc/articles/PMC7898663/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bi-allelic loss-of-function variants in BCAS3 cause a syndromic neurodevelopmental disorder
    1
    1. scibot 25 Jul 2024
      BDSC #8816

      DOI: 10.1016/j.ajhg.2021.04.024

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    ncbi.nlm.nih.gov/pmc/articles/PMC8206390/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a Drosophila Model of Amyotrophic Lateral Sclerosis
    1
    1. scibot 24 Jul 2024
      8816

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    ncbi.nlm.nih.gov/pmc/articles/PMC10486503/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Octopamine signaling via OctαR is essential for a well-orchestrated climbing performance of adult Drosophila melanogaster
    1
    1. scibot 19 Jul 2024
      8816

      DOI: 10.1038/s41598-022-18203-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC9388497/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Botulinum neurotoxin accurately separates tonic vs. phasic transmission and reveals heterosynaptic plasticity rules in Drosophila
    1
    1. scibot 19 Jul 2024
      8816

      DOI: 10.7554/eLife.77924

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    ncbi.nlm.nih.gov/pmc/articles/PMC9439677/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The auxiliary glutamate receptor subunit dSol-1 promotes presynaptic neurotransmitter release and homeostatic potentiation
    1
    1. scibot 18 Jul 2024
      https://www.pnas.org/lookup/suppl/doi:10.1073/pnas.1915464117/-/DCSupplemental.

      DOI: 10.1073/pnas.1915464117

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    ncbi.nlm.nih.gov/pmc/articles/PMC7568321/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small heat shock proteins determine synapse number and neuronal activity during development
    1
    1. scibot 16 Jul 2024
      BL-8816

      DOI: 10.1371/journal.pone.0233231

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    ncbi.nlm.nih.gov/pmc/articles/PMC7241713/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function
    1
    1. scibot 15 Jul 2024
      8816

      DOI: 10.1016/j.isci.2021.102899

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    ncbi.nlm.nih.gov/pmc/articles/PMC8358705/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATP-citrate lyase promotes axonal transport across species
    1
    1. scibot 14 Jul 2024
      8816

      DOI: 10.1038/s41467-021-25786-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC8497606/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure and function
    1
    1. scibot 13 Jul 2024
      8816

      DOI: 10.1371/journal.pone.0221006

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    ncbi.nlm.nih.gov/pmc/articles/PMC7080231/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNAi of Complex I and V of the electron transport chain in glutamate neurons extends life span, increases sleep, and decreases locomotor activity in Drosophila melanogaster
    1
    1. scibot 13 Jul 2024
      8816

      DOI: 10.1371/journal.pone.0286828

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    ncbi.nlm.nih.gov/pmc/articles/PMC10270625/
  25. 52.53.155.43 52.53.155.43
    Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate
    1
    1. scibot 13 Jul 2024
      BDSC 8816

      DOI: 10.1083/jcb.201904148

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    52.53.155.43/8367afa0072963dd46d57c10d39ab722075d61c7/JCB_201904148_sm-html.html
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding
    1
    1. scibot 13 Jul 2024
      RRID:BDSC_8816

      DOI: 10.7554/eLife.52009

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    ncbi.nlm.nih.gov/pmc/articles/PMC7021487/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel in‐frame deletion in KIF5C gene causes infantile onset epilepsy and psychomotor retardation
    1
    1. scibot 10 Jul 2024
      8816

      DOI: 10.1002/mco2.469

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960728/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration
    1
    1. scibot 09 Jul 2024
      BL8816

      DOI: 10.1371/journal.pbio.3000545

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    ncbi.nlm.nih.gov/pmc/articles/PMC6917273/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CHD Protein Kismet Restricts the Synaptic Localization of Cell Adhesion Molecules at the Drosophila Neuromuscular Junction
    1
    1. scibot 06 Jul 2024
      RRID:BDSC_8816

      DOI: 10.3390/ijms25053074

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    ncbi.nlm.nih.gov/pmc/articles/PMC10931923/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport
    1
    1. scibot 05 Jul 2024
      8816

      DOI: 10.1007/s00401-024-02689-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10873455/
  31. May 2024
  32. academic.oup.com academic.oup.com
    Humanized Drosophila Model of the Meier-Gorlin Syndrome Reveals Conserved and Divergent Features of the Orc6 Protein
    2
    1. scibot 15 May 2024
      8816

      DOI: 10.1534/genetics.120.303698

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      RRID:BDSC_8816 DOI:10.1534/genetics.120.303698
    2. scibot 15 May 2024
      8816

      DOI: 10.1534/genetics.120.303698

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    academic.oup.com/genetics/article/216/4/995/6065819
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simplified homology-assisted CRISPR for gene editing in Drosophila
    1
    1. scibot 07 May 2024
      8816

      DOI: 10.1093/g3journal/jkad277

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    ncbi.nlm.nih.gov/pmc/articles/PMC10849607/
  34. Mar 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CHD family chromatin remodeling enzyme, Kismet, promotes both clathrin-mediated and activity-dependent bulk endocytosis
    1
    1. scibot 23 Mar 2024
      RRID:BDSC_8816

      DOI: 10.1371/journal.pone.0300255

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    ncbi.nlm.nih.gov/pmc/articles/PMC10956772/
  36. Feb 2024
  37. www.science.org www.science.org
    ATAT1-enriched vesicles promote microtubule acetylation via axonal transport
    1
    1. scibot 13 Feb 2024
      BDSC 8816

      DOI: 10.1126/sciadv.aax2705

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    science.org/doi/10.1126/sciadv.aax2705
  38. www.nature.com www.nature.com
    CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum
    1
    1. scibot 10 Feb 2024
      8816

      DOI: 10.1038/s41436-019-0585-z

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    nature.com/articles/s41436-019-0585-z
  39. journals.plos.org journals.plos.org
    Hyperpolarization by activation of halorhodopsin results in enhanced synaptic transmission: Neuromuscular junction and CNS circuit
    1
    1. scibot 09 Feb 2024
      BDSC # 8816

      DOI: 10.1371/journal.pone.0200107

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    journals.plos.org/plosone/article
  40. www.biorxiv.org www.biorxiv.org
    Examining the potential involvement of NONO in TDP-43 proteinopathy in Drosophila
    1
    1. scibot 09 Feb 2024
      RRID:BDSC_8816

      DOI: 10.1101/2023.12.13.571416

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    biorxiv.org/content/10.1101/2023.12.13.571416v1
  41. Jan 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster
    1
    1. scibot 28 Jan 2024
      8816

      DOI: 10.1016/j.neulet.2018.12.009

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    sciencedirect.com/science/article/abs/pii/S0304394018308553
  43. journals.plos.org journals.plos.org
    A comparison of three different methods of eliciting rapid activity-dependent synaptic plasticity at the Drosophila NMJ
    1
    1. scibot 17 Jan 2024
      BDSC stock #8816

      DOI: 10.1371/journal.pone.0260553

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  44. Oct 2023
  45. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 17 Oct 2023
      RRID: BDSC_8816

      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
  46. Jul 2023
  47. link.springer.com link.springer.com
    A Novel Drosophila-based Drug Repurposing Platform Identified Fingolimod As a Potential Therapeutic for TDP-43 Proteinopathy
    1
    1. scibot 29 Jul 2023
      RRID:BDSC_8816

      DOI: 10.1007/s13311-023-01406-z

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    link.springer.com/article/10.1007/s13311-023-01406-z
  48. Nov 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila
    1
    1. scibot 22 Nov 2022
      RRID: BDSC _8816

      DOI: 10.1016/j.isci.2022.105476

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    ncbi.nlm.nih.gov/pmc/articles/PMC9672966/
  50. Mar 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models
    1
    1. scibot 26 Mar 2022
      BDSC:8816

      DOI: 10.1016/j.devcel.2022.02.022

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    sciencedirect.com/science/article/pii/S1534580722001241
  52. Dec 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Distinct molecular pathways govern presynaptic homeostatic plasticity
    1
    1. scibot 15 Dec 2021
      BDSC:8816

      DOI: 10.1016/j.celrep.2021.110105

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    sciencedirect.com/science/article/pii/S2211124721015990
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macros to Quantify Exosome Release and Autophagy at the Neuromuscular Junction of Drosophila Melanogaster
    1
    1. scibot 04 Dec 2021
      BDSC:8816

      DOI: 10.3389/fcell.2021.773861

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  55. Aug 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.neuron.2017.07.038

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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis
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  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ethanol stimulates the in vivo axonal movement of neuropeptide dense‐core vesicles in Drosophila motor neurons
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      DOI: 10.1111/jnc.14230

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  59. Jul 2021
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in Drosophila Glutamatergic Neurons
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      RRID:BDSC_8816

      DOI: 10.1523/JNEUROSCI.0908-18.2018

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  62. www.sciencedirect.com www.sciencedirect.com
    Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT
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    sciencedirect.com/science/article/pii/S0896627317306864
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin
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      DOI: 10.7554/eLife.26886

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  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation
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    1. scibot 07 May 2021
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  67. Feb 2021
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of FoxP circuits involved in locomotion and object fixation in Drosophila
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3
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      DOI: 10.7554/eLife.60132

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    ncbi.nlm.nih.gov/pmc/articles/PMC7748415/
  70. Sep 2020
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding
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      DOI: 10.7554/eLife.52009

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  72. Nov 2018
  73. www.jneurosci.org www.jneurosci.org
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    jneurosci.org/content/38/35/7741
  74. www.sciencedirect.com www.sciencedirect.com
    Hsp90 Mediates Membrane Deformation and Exosome Release
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      BDSC:8816

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    sciencedirect.com/science/article/pii/S1097276518305859
  75. Nov 2017
  76. www.sciencedirect.com www.sciencedirect.com
    Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration
    1
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  77. www.jneurosci.org www.jneurosci.org
    The Spacing Effect for Structural Synaptic Plasticity Provides Specificity and Precision in Plastic Changes
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    1. scibot 08 Nov 2017
      BDSC_8816

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    jneurosci.org/content/37/19/4992
  78. www.sciencedirect.com www.sciencedirect.com
    Intra-neuronal Competition for Synaptic Partners Conserves the Amount of Dendritic Building Material
    1
    1. scibot 08 Nov 2017
      BDSC_8816

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S089662731631042X