54 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    miRNA-mediated gene silencing in Drosophila larval development involves GW182-dependent and independent mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612316/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the integrated stress response or Ataxin-2 alleviates neurodegeneration in PolyGR models of C9orf72 associated frontotemporal dementia and amyotrophic lateral sclerosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13251143/
  4. Mar 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cul-4 inhibition rescues spastin levels and reduces defects in hereditary spastic paraplegia models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11449140/
  6. Feb 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila Unfolded Protein Response (UPR) assays in vitro and in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC9764256/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel de novo heterozygous DYRK1A mutation causes complete loss of DYRK1A function and developmental delay
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    pmc.ncbi.nlm.nih.gov/articles/PMC7299959/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ADAM17‐triggered TNF signalling protects the ageing Drosophila retina from lipid droplet‐mediated degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC7459420/
  10. Oct 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12495114/
  12. Sep 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alzheimer’s Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC6581016/
  14. Aug 2025
  15. 52.53.155.43 52.53.155.43
    41467_2023_42626_MOESM1_ESM (2)-html.html
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    52.53.155.43/c8782fdcc7411faae6d347135cd9542aa7c6c117/41467_2023_42626_MOESM1_ESM (2)-html.html
  16. Jul 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR Gene Drive Efficiency and Resistance Rate Is Highly Heritable with No Common Genetic Loci of Large Effect
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    pmc.ncbi.nlm.nih.gov/articles/PMC6499522/
  18. Jun 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuronal overexpression of Alzheimer's disease and Down's syndrome associated DYRK1A/minibrain gene alters motor decline, neurodegeneration and synaptic plasticity in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC6419573/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Low-dose ionizing radiation alleviates Aβ42-induced cell death via regulating AKT and p38 pathways in Drosophila Alzheimer's disease models
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    pmc.ncbi.nlm.nih.gov/articles/PMC6398453/
  21. 52.53.155.43 52.53.155.43
    m-12-00049-sup1-html.html
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    52.53.155.43/baa0686b74bef69243af00033ac5d92973c00dd4/fq5025sup1-html.html
  22. May 2025
  23. academic.oup.com academic.oup.com
    Genetic screening reveals cone cell-specific factors as common genetic targets modulating rival-induced prolonged mating in male Drosophila melanogaster
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    academic.oup.com/g3journal/article/15/1/jkae255/7868166
  24. 52.53.155.43 52.53.155.43
    m-12-00049-sup1-html.html
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    52.53.155.43/baa0686b74bef69243af00033ac5d92973c00dd4/fq5025sup1-html.html
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alcohol Activates Scabrous-Notch to Influence Associated Memories
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    pmc.ncbi.nlm.nih.gov/articles/PMC6323638/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glucose uptake in pigment glia suppresses Tau-induced inflammation and photoreceptor degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067088/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuronal polyunsaturated fatty acids are protective in ALS/FTD
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    pmc.ncbi.nlm.nih.gov/articles/PMC11976277/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Restoration of Shal/KV4 proteostasis and motor function in a Drosophila model of spinocerebellar ataxia type 19/22
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037467/
  29. Apr 2025
  30. www.sciencedirect.com www.sciencedirect.com
    Drosophila SPARC collagen IV chaperone-like activity essential for development is unique to the fat body
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    sciencedirect.com/science/article/pii/S2589004225003712
  31. Feb 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals
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    pmc.ncbi.nlm.nih.gov/articles/PMC5944365/
  33. Nov 2024
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined inactivation of RB and Hippo converts differentiating Drosophila photoreceptors into eye progenitor cells through derepression of homothorax
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    pmc.ncbi.nlm.nih.gov/articles/PMC10842633/
  35. Sep 2024
  36. Local file Local file
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  37. Aug 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299523/
  39. www.sciencedirect.com www.sciencedirect.com
    The JNK and Hippo pathways control epithelial integrity and prevent tumor initiation by regulating an overlapping transcriptome
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    sciencedirect.com/science/article/pii/S0960982224009990
  40. Jul 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel dominant and recessive variants in human ROBO1 cause distinct neurodevelopmental defects through different mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC9402236/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila Homeodomain-Interacting Protein Kinase (Hipk) Phosphorylates the Hippo/Warts Signalling Effector Yorkie
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    ncbi.nlm.nih.gov/pmc/articles/PMC7918113/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bassoon contributes to tau-seed propagation and neurotoxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9708566/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC8328392/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10463776/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DYRK1a Inhibitor Mediated Rescue of Drosophila Models of Alzheimer’s Disease-Down Syndrome Phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9345315/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Roles of ZnT86D in Neurodevelopment and Pathogenesis of Alzheimer Disease in a Drosophila melanogaster Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9569493/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7953826/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine Synthetase 1 Increases Autophagy Lysosomal Degradation of Mutant Huntingtin Aggregates in Neurons, Ameliorating Motility in a Drosophila Model for Huntington’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC7016901/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CORO7 functions as a scaffold protein for the core kinase complex assembly of the Hippo pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC7949047/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual Leucine Zipper Kinase Regulates Dscam Expression through a Noncanonical Function of the Cytoplasmic Poly(A)-Binding Protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC9351639/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9508268/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARMS-NF-κB signaling regulates intracellular ROS to induce autophagy-associated cell death upon oxidative stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC9926119/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC6895427/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function
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    ncbi.nlm.nih.gov/pmc/articles/PMC10582172/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disrupted nuclear import of cell cycle proteins in Huntington's/PolyQ disease causes neurodevelopment defects in cellular and Drosophila model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10906312/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC11001582/
  58. May 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10940166/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting RACK1 to alleviate TDP-43 and FUS proteinopathy-mediated suppression of protein translation and neurodegeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10726565/
  61. Mar 2024
  62. rupress.org rupress.org
    Medioapical contractile pulses coordinated between cells regulate Drosophila eye morphogenesis
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    rupress.org/jcb/article/223/2/e202304041/276471/Medioapical-contractile-pulses-coordinated-between
  63. Feb 2024
  64. www.nature.com www.nature.com
    Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling
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    nature.com/articles/s41467-020-16858-6
  65. www.tandfonline.com www.tandfonline.com
    Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy
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    tandfonline.com/doi/full/10.1080/15548627.2019.1596477
  66. Dec 2023
  67. elifesciences.org elifesciences.org
    Differentiation signals from glia are fine-tuned to set neuronal numbers during development
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    elifesciences.org/articles/78092
  68. Mar 2023
  69. www.sciencedirect.com www.sciencedirect.com
    Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD
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    sciencedirect.com/science/article/pii/S0896627323001332
  70. Sep 2021
  71. www.sciencedirect.com www.sciencedirect.com
    Regulation of lipid homeostasis by the TBC protein dTBC1D22 via modulation of the small GTPase Rab40 to facilitate lipophagy
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    sciencedirect.com/science/article/pii/S221112472100975X
  72. Jul 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
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    ncbi.nlm.nih.gov/pmc/articles/PMC6895427/
  74. Apr 2021
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC8007214/
  76. Jan 2020
  77. www.jneurosci.org www.jneurosci.org
    Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in Drosophila
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    jneurosci.org/content/39/27/5269