178 Matching Annotations
  1. Last 7 days
  2. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    AP2M1 Amplification Orchestrates Notch-Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202514566
  3. Oct 2025
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    Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation
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    sciencedirect.com/science/article/pii/S2211124725011507
  5. Sep 2025
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    Directed-complement killing of Pseudomonas aeruginosa protects against lethal pneumonia
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    sciencedirect.com/science/article/pii/S2352396425003706
  7. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia-Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling-Mediated Neutrophil Extracellular Traps Formation
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509952
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor associated neutrophils promote prostate cancer progression by mediating neutrophil trap secretion through PSMA1- NF-κB-HIF-1α signaling axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399615/
  9. Aug 2025
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    Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis
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    biorxiv.org/content/10.1101/2025.08.15.670286v1
  11. 52.53.155.43 52.53.155.43
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  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12356262/
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    science.org/doi/10.1126/sciadv.adx6587
  14. Jul 2025
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    Nostoc commune-derived scytonemin induced mitochondrial cell death in leukemia models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12267311/
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    CircTADA2A inhibits cell proliferation and promotes ferroptosis by sponging miR-638 in acute myeloid leukemia
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    link.springer.com/article/10.1007/s13577-025-01251-6
  18. Jun 2025
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    Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling
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    sciencedirect.com/science/article/pii/S153561082500220X
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of a Novel Bifunctional Anti-CD47 Fusion Protein with Improved Efficacy and a Favorable Safety Profile
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    pmc.ncbi.nlm.nih.gov/articles/PMC12134747/
  22. May 2025
  23. www.cell.com www.cell.com
    CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
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    Frictiotaxis underlies focal adhesion-independent durotaxis
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    The m5C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism
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    sciencedirect.com/science/article/pii/S2211124725004322
  26. Apr 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway–Deficient Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12011380/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984389/
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    Myeloperoxidase impacts vascular function by altering perivascular adipocytes’ secretome and phenotype in obesity
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LNS8801: An Enantiomerically Pure Agonist of the G Protein–Coupled Estrogen Receptor Suitable for Clinical Development
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  31. retrovirology.biomedcentral.com retrovirology.biomedcentral.com
    Aberrant expression of human endogenous retrovirus K9-derived elements is associated with better clinical outcome of acute myelocytic leukemia
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  32. Mar 2025
  33. 52.53.155.43 52.53.155.43
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  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway
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  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alterations in neutrophil mRNA profiles in multiple sclerosis and identification of candidate genes for further investigation
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  37. Feb 2025
  38. aacrjournals.org aacrjournals.org
    The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL-15R signaling
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    The CDK4/6 inhibitor Palbociclib synergizes with ATRA to induce differentiation in AML
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  42. Jan 2025
  43. www.nature.com www.nature.com
    Sialic acid aptamer and RNA in situ hybridization-mediated proximity ligation assay for spatial imaging of glycoRNAs in single cells
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    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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    Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells
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  46. Dec 2024
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    Insights into biofilm architecture and maturation enable improved clinical strategies for exopolysaccharide-targeting therapeutics
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    A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex
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    Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
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    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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  51. Nov 2024
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11487346/
  53. Oct 2024
  54. aacrjournals.org aacrjournals.org
    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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  55. Sep 2024
  56. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF521 promotes acute myeloid leukemogenesis by suppressing the expression and acetylation of SMC3
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    ncbi.nlm.nih.gov/pmc/articles/PMC11415694/
  58. Aug 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies
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  60. Jul 2024
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    NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
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  64. www.nature.com www.nature.com
    Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells
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  66. Jun 2024
  67. www.sciencedirect.com www.sciencedirect.com
    An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms
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  68. May 2024
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    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin-specific protease 7 inhibitors reveal a differentiated mechanism of p53-driven anti-cancer activity
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  72. 52.53.155.43 52.53.155.43
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  73. Apr 2024
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    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acquired immune resistance is associated with interferon signature and modulation of KLF6/c-MYB transcription factors in myeloid leukemia
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    onlinelibrary.wiley.com/doi/10.1002/eji.202350717
  77. Mar 2024
  78. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
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    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
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    A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation
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    PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages
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    A humoral stress response protects Drosophila tissues from antimicrobial peptides
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  83. Feb 2024
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    IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression
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    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
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  86. Jan 2024
  87. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1
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    bmccancer.biomedcentral.com/articles/10.1186/s12885-024-11898-3
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    An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo
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    ALDH3A1 upregulation inhibits neutrophils N2 polarization and halts oral cancer growth
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    onlinelibrary.wiley.com/doi/10.1111/odi.14863
  90. Dec 2023
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    A helicase-independent role of DHX15 promotes MYC stability and acute leukemia cell survival
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    trans-Endothelial neutrophil migration activates bactericidal function via Piezo1 mechanosensing
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  93. www.biorxiv.org www.biorxiv.org
    MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells
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    biorxiv.org/content/10.1101/2023.11.15.567209v1
  94. Nov 2023
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    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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  97. www.science.org www.science.org
    Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies
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  98. Sep 2023
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    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
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    PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy
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  101. Aug 2023
  102. link.springer.com link.springer.com
    Discovery of a novel marker for human granulocytes and tissue macrophages: RTL1 revisited
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  103. Jun 2023
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    Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  107. May 2023
  108. www.biorxiv.org www.biorxiv.org
    Killing the enemy or making it your ally? The effects of thiostrepton on tumor associated macrophages
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  109. Apr 2023
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    Synergistic antiproliferative activity of quercetin and... : Anti-Cancer Drugs
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    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
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  225. Nov 2018
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    A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response
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    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
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    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
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  231. Nov 2017
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    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
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    Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone
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    Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
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    Lactoferrin Suppresses Neutrophil Extracellular Traps Release in Inflammation
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