231 Matching Annotations
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    5-Azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia
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    sciencedirect.com/science/article/pii/S1097276526005873
  3. Sep 2026
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    Bone marrow stromal cells promote chemoresistance in acute myeloid leukaemia through P2RX7-mediated antioxidant defence
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    nature.com/articles/s12276-026-01839-4
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    MYDGF as a telomerase activator and therapeutic target for osteoarthritis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13530092/
  6. Aug 2026
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    Intracellular iron homeostasis-regulated epigenetic reprogramming contributes to −7/del(7q) leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC13482816/
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    Amiaspochalasins I and J, Undescribed Aspochalasins with Antibacterial Activities From Aspergillus micronesiensis
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    Protocol to investigate the role of NETosis in health and disease via a high-throughput neutrophil-like model using quantitative imaging
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    pmc.ncbi.nlm.nih.gov/articles/PMC13471202/
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    Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia
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    aacrjournals.org/bloodcancerdiscov/article/7/4/624/786176/Rapid-Transcription-Dynamics-Confers-Cytarabine
  11. Jul 2026
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    A structure-based modeling approach identifies effective drug combinations for RAS-mutant acute myeloid leukemia
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    Oxygen-stable streptolysin O variant enables mitochondrial ATP synthesis analysis in minimal cells blood and tissues
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    A MERTK-Targeting Antibody-Drug Conjugate Selectively Depletes M2 Tumor-Associated Macrophages and MERTK-Expressing Cancer Cells
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  16. Jun 2026
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    Development of CAR T cells Targeting a Surface RNA Binding Protein for the Treatment of Acute Leukemias
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    Micro-Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro-Regenerative Bone Healing
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  19. May 2026
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    Enhanced formaldehyde clearance ameliorates differentiation-induced genotoxicity in Fanconi anemia mutant cells
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    Novel noscapine derivative induces AML differentiation by dual-engaging DHODH and mitochondrial lipids to trigger a metabolic–epigenetic–transcriptional cascade
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    LDLRAD2 drives glycolysis and angiogenesis to promote extramedullary infiltration in acute myeloid leukemia
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    Cytotoxic Profiling of 3′,4′,5′-Trimethoxychalcones Reveals Cell-Line-Dependent Cytotoxic Activity: An In Vitro and In Silico Study
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    Leukemic stem cell subtypes determine venetoclax resistance and therapeutic vulnerabilities in AML
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  25. Apr 2026
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancement of CD117-targeted bispecific T-cell engagement by CD33-targeted bispecific T-cell co-stimulation in acute myeloid leukemia
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    Anticancer Potential of Piericidin A1 and Derivatives Isolated From Streptomyces sp. Associated With Palythoa variabilis From Brazilian Reefs
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    Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment
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    High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration
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    m6A modification of ATOX1 inhibits acute myeloid leukemia progression by promoting cuproptosis
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    The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
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  33. Mar 2026
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    Enalaprilat reverses neutrophil polarization imbalance via targeting taurine-STING axis for treatment of diabetic wounds
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    Nanobody-Engineered CLL-1 CAR-T Cells: Optimizing Tumor-Specific Cytotoxicity and Minimizing Off-Tumor Toxicity
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    Biomimetic Copper-Doped Nano-Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia
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    RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia
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    Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia
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    Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
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  42. Feb 2026
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    Targeting UGCG sensitizes AML cells to venetoclax through RAB32-mediated endoplasmic reticulum-mitochondria communication
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    DualPG-DTA: A Large Language Model-Powered Graph Neural Network Framework for Enhanced Drug-Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti-Leukemia Activity
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  49. Jan 2026
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    METTL3 promotes neutrophil extracellular trap formation via SYK/ERK/MEK signaling during acute lung injury
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    Distinct Regulation of the ARF and TAp73 Tumor Suppressor Genes by the Transcription Factor E2F1 Enables Discrimination of Cancer Cells from Normal Growing Cells
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    Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia
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    ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia
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  54. Dec 2025
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    Integrated scFv identification and CAR T cell generation for AML targeting in vivo
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    Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor-Associated Neutrophils to Sensitize Immunotherapy
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  58. Nov 2025
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    Targeting Matrix Metalloproteinase-9 to Alleviate T Cell Exhaustion and Improve Sepsis Prognosis
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    Network pharmacology, molecular docking, and experimental validation-based approach to explore the mechanism of action of ginsenoside Rh4 on acute myeloid leukemia cells
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    Global genome analysis identifies glycolipids and lipoteichoic acid alanylation as contributors to group B streptococcal diabetic wound infection
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  63. Oct 2025
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    A generalized strategy to kill leukemic cells by targeting the regulatory systems governing mitochondrial membrane potential
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    AP2M1 Amplification Orchestrates Notch-Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients
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    Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation
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  67. Sep 2025
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    Directed-complement killing of Pseudomonas aeruginosa protects against lethal pneumonia
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    Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia-Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling-Mediated Neutrophil Extracellular Traps Formation
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  71. Aug 2025
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    Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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  76. Jul 2025
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    Nostoc commune-derived scytonemin induced mitochondrial cell death in leukemia models
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    CircTADA2A inhibits cell proliferation and promotes ferroptosis by sponging miR-638 in acute myeloid leukemia
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    link.springer.com/article/10.1007/s13577-025-01251-6
  80. Jun 2025
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    Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling
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    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    Development of a Novel Bifunctional Anti-CD47 Fusion Protein with Improved Efficacy and a Favorable Safety Profile
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  84. May 2025
  85. www.cell.com www.cell.com
    CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
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    Frictiotaxis underlies focal adhesion-independent durotaxis
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    The m5C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism
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  88. Apr 2025
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway–Deficient Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12011380/
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1
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    Myeloperoxidase impacts vascular function by altering perivascular adipocytes’ secretome and phenotype in obesity
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    LNS8801: An Enantiomerically Pure Agonist of the G Protein–Coupled Estrogen Receptor Suitable for Clinical Development
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    Aberrant expression of human endogenous retrovirus K9-derived elements is associated with better clinical outcome of acute myelocytic leukemia
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    retrovirology.biomedcentral.com/articles/10.1186/s12977-025-00661-6
  94. Mar 2025
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    BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway
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    Alterations in neutrophil mRNA profiles in multiple sclerosis and identification of candidate genes for further investigation
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  99. Feb 2025
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    The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL-15R signaling
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    Impact of scFv on functionality and safety of third generation CD123 CAR T cells
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