317 Matching Annotations
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    Therapeutic potential of third-generation chimeric antigen receptor T cells targeting B cell maturation antigen for treating multiple myeloma
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    1. scibot 02 May 2024
      RRID:CVCL_0004

      DOI: 10.1007/s10238-024-01347-7

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    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
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    1. scibot 30 Apr 2024
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    sciencedirect.com/science/article/pii/S1097276524002843
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039342/
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    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
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    1. scibot 26 Apr 2024
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  6. Apr 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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    sciencedirect.com/science/article/pii/S2211124724004728
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    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
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    Protocol for isolation of tumor-derived extracellular vesicles and functional studies on human T cell subsets
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    sciencedirect.com/science/article/pii/S266616672400176X
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    A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response
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    Chromatin context-dependent regulation and epigenetic manipulation of prime editing
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    1. scibot 12 Apr 2024
      CCL-243

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  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma
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    1. scibot 03 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983114/
  13. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    1. scibot 29 Mar 2024
      CCL-243

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    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
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    1. scibot 19 Mar 2024
      RRID: CVCL_0004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
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    EPC1/2 regulate hematopoietic stem and progenitor cell proliferation by modulating H3 acetylation and DLST
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    1. scibot 07 Mar 2024
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  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced representative methylome profiling of cell-free DNA for breast cancer detection
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    1. scibot 02 Mar 2024
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  18. Feb 2024
  19. 52.53.155.43 52.53.155.43
    176-html.html
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    Anti-Vα24Jα18 TCR antibody tunes iNKT cell responses to target and kill CD1d-negative tumors in an FcγRII (CD32)-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875981/
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    SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
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      ATCC# CCL-243

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    sciencedirect.com/science/article/pii/S1550413124000135
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    ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion
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    Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing
    1
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infection
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    Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites
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    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  27. Jan 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Short tandem repeat profiling via next-generation sequencing for cell line authentication
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      CVCL_0004

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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-15-dependent immune crosstalk between natural killer cells and dendritic cells in HIV-1 elite controllers
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      CVCL_004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10765318/
  30. link.springer.com link.springer.com
    Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
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  31. Dec 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
    1
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      JCRB0019

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  35. Nov 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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  37. www.nature.com www.nature.com
    Scalable single-cell profiling of chromatin modifications with sciCUT&Tag
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    nature.com/articles/s41596-023-00905-9
  38. link.springer.com link.springer.com
    Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
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    1. scibot 10 Nov 2023
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    link.springer.com/article/10.1186/s12967-023-04669-4
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screen for genome‐wide interrogation of essential MYC‐bound E‐boxes in cancer cells
    1
    1. scibot 09 Nov 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10620128/
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    Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells
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  41. Oct 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unedited allogeneic iNKT cells show extended persistence in MHC-mismatched canine recipients
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    ncbi.nlm.nih.gov/pmc/articles/PMC10591065/
  43. www.nature.com www.nature.com
    A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
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      DOI: 10.1038/s41556-023-01248-z

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  44. www.sciencedirect.com www.sciencedirect.com
    Enhanced antitumor efficacy, proliferative capacity, and alleviation of T cell exhaustion by fifth-generation chimeric antigen receptor T cells targeting B cell maturation antigen in multiple myeloma
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      RRID:CVCL_0004

      DOI: 10.1016/j.biopha.2023.115691

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    sciencedirect.com/science/article/pii/S0753332223014890
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics
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      RRID:CVCL_0004

      DOI: 10.1136/jitc-2023-007097

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    ncbi.nlm.nih.gov/pmc/articles/PMC10537849/
  46. Sep 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
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      RRID:CVCL_0004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
  48. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Yin-html.html
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      DOI: 10.1111/bph.16245

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    52.53.155.43/3f4c3b7a8c80fd686d3f27ef9d97ee6662a4385e/British J Pharmacology - 2023 - Yin-html.html
  49. Aug 2023
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eradication of CD48 positive tumors by selectively enhanced YTS cells harnessing the lncRNA NeST
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    ncbi.nlm.nih.gov/pmc/articles/PMC10440710/
  51. www.biorxiv.org www.biorxiv.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 16 Aug 2023
      RRID:CVCL_0004

      DOI: 10.1101/2023.07.26.550648

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    biorxiv.org/content/10.1101/2023.07.26.550648v2
  52. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B1
    1
    1. scibot 03 Aug 2023
      RRID:CVCL_0004

      DOI: 10.1002/1878-0261.13486

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13486
  53. Jul 2023
  54. link.springer.com link.springer.com
    Good manufacturing practice production of CD34+ progenitor-derived NK cells for adoptive immunotherapy in acute myeloid leukemia
    1
    1. scibot 22 Jul 2023
      RRID:CVCL_0004

      DOI: 10.1007/s00262-023-03492-6

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    link.springer.com/article/10.1007/s00262-023-03492-6
  55. 52.53.155.43 52.53.155.43
    Conditional lethality profiling reveals anticancer mechanisms of action and drug-nutrient interactions
    1
    1. scibot 19 Jul 2023
      RRID:_CVCL_0004

      DOI: 10.1101/2023.06.04.543621

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    52.53.155.43/402e9ae446be9d7677d004a8f8e22b2d6ac49df1/2023.06.04.543621v1.full-html.html
  56. Jun 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models
    1
    1. scibot 30 Jun 2023
      RRID:CVCL_0004

      DOI: 10.3389/fonc.2023.1200897

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    ncbi.nlm.nih.gov/pmc/articles/PMC10294234/
  58. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
    1
    1. scibot 24 Jun 2023
      RRID: CVCL_0004

      DOI: 10.1038/s41467-023-39241-7

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    nature.com/articles/s41467-023-39241-7
  59. link.springer.com link.springer.com
    The antitumor effects of WNT5A against hematological malignancies
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    1. scibot 15 Jun 2023
      RRID:CVCL_0004

      DOI: 10.1007/s12079-023-00773-8

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  60. dx.doi.org dx.doi.org
    EBV-upregulated B7-H3 inhibits NK cell-mediated antitumor function and contributes to nasopharyngeal carcinoma progression
    1
    1. scibot 10 Jun 2023
      RRID:CVCL_0004

      DOI: 10.1158/2326-6066.CIR-22-0374

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    dx.doi.org/10.1158/2326-6066.CIR-22-0374
  61. www.sciencedirect.com www.sciencedirect.com
    Minor intron splicing is critical for survival of lethal prostate cancer
    1
    1. scibot 09 Jun 2023
      RRID: CCL-243

      DOI: 10.1016/j.molcel.2023.05.017

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    sciencedirect.com/science/article/pii/S1097276523003738
  62. www.sciencedirect.com www.sciencedirect.com
    Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia
    1
    1. scibot 09 Jun 2023
      RRID:CVCL_0004

      DOI: 10.1016/j.ccell.2023.05.002

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    sciencedirect.com/science/article/pii/S1535610823001691
  63. www.science.org www.science.org
    Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis
    1
    1. scibot 02 Jun 2023
      RRID:CVCL_0004

      DOI: 10.1126/sciimmunol.adg3196

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    science.org/doi/10.1126/sciimmunol.adg3196
  64. link.springer.com link.springer.com
    Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7
    1
    1. scibot 01 Jun 2023
      RRID:CVCL_0004

      DOI: 10.1007/s00018-023-04816-6

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    link.springer.com/article/10.1007/s00018-023-04816-6
  65. May 2023
  66. link.springer.com link.springer.com
    Potential role of the P2X7 receptor in the proliferation of human diffused large B-cell lymphoma
    1
    1. scibot 25 May 2023
      RRID:CVCL_0004

      DOI: 10.1007/s11302-023-09947-w

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  67. link.springer.com link.springer.com
    Discovery of two new isoforms of the human DUT gene
    1
    1. scibot 13 May 2023
      CVCL_0004

      DOI: 10.1038/s41598-023-32970-1

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  68. www.biorxiv.org www.biorxiv.org
    Killing the enemy or making it your ally? The effects of thiostrepton on tumor associated macrophages
    1
    1. scibot 09 May 2023
      CCL-243

      DOI: 10.1101/2023.03.23.533899

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    biorxiv.org/content/10.1101/2023.03.23.533899v1
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reverse translation identifies the synergistic role of immune checkpoint blockade and IL-15 to enhance immunotherapy of ovarian cancer
    1
    1. scibot 06 May 2023
      RRID:CVCL_0004

      DOI: 10.1158/2326-6066.CIR-22-0600

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    ncbi.nlm.nih.gov/pmc/articles/PMC10155036/
  70. Apr 2023
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types
    1
    1. scibot 12 Apr 2023
      ATCC, CCL-243

      DOI: 10.1101/2023.03.05.531189

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    ncbi.nlm.nih.gov/pmc/articles/PMC10028905/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-suppressor scanning for systematic discovery of drug resistance mutations
    1
    1. scibot 12 Apr 2023
      RRID:CVCL_0004

      DOI: 10.1002/cpz1.614

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    ncbi.nlm.nih.gov/pmc/articles/PMC10073897/
  73. link.springer.com link.springer.com
    Development of an antibody-ligand fusion protein scFvCD16A-sc4-1BBL in Komagataella phaffii with stimulatory activity for Natural Killer cells
    1
    1. scibot 12 Apr 2023
      RRID:CVCL_0004

      DOI: 10.1186/s12934-023-02082-6

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  74. Mar 2023
  75. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    1. scibot 29 Mar 2023
      RRID:CVCL_0004

      DOI: 10.1002/1878-0261.13422

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13422
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tri-specific killer engager against mesothelin targets NK cells towards lung cancer
    1
    1. scibot 16 Mar 2023
      CVCL_0004

      DOI: 10.3389/fimmu.2023.1060905

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    ncbi.nlm.nih.gov/pmc/articles/PMC9992642/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced Costimulatory Signaling Improves CAR T-cell Effector Responses in CLL
    1
    1. scibot 16 Mar 2023
      RRID:CVCL_0004

      DOI: 10.1158/2767-9764.CRC-22-0200

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    ncbi.nlm.nih.gov/pmc/articles/PMC10010331/
  78. www.sciencedirect.com www.sciencedirect.com
    Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes
    1
    1. scibot 11 Mar 2023
      RRID:CVCL_0004

      DOI: 10.1016/j.molcel.2023.02.013

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    sciencedirect.com/science/article/pii/S1097276523001168
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery
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    1. scibot 02 Mar 2023
      RRID:CVCL_0004

      DOI: 10.7554/eLife.80640

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    ncbi.nlm.nih.gov/pmc/articles/PMC9946446/
  80. Feb 2023
  81. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD
    1
    1. scibot 17 Feb 2023
      RRID:CVCL_0004

      DOI: 10.1002/1878-0261.13368

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13368
  82. www.nature.com www.nature.com
    Quantitative multiple fragment monitoring with enhanced in-source fragmentation/annotation mass spectrometry
    1
    1. scibot 11 Feb 2023
      RRID:CVCL_0004

      DOI: 10.1038/s41596-023-00803-0

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    nature.com/articles/s41596-023-00803-0
  83. Jan 2023
  84. www.nature.com www.nature.com
    Chem-map profiles drug binding to chromatin in cells
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    1. scibot 27 Jan 2023
      RRID:CVCL_0004

      DOI: 10.1038/s41587-022-01636-0

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  85. www.sciencedirect.com www.sciencedirect.com
    Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma
    1
    1. scibot 26 Jan 2023
      CCL-243

      DOI: 10.1016/j.devcel.2022.12.012

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    sciencedirect.com/science/article/pii/S1534580722008942
  86. www.science.org www.science.org
    Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis
    1
    1. scibot 26 Jan 2023
      RRID:CVCL_0004

      DOI: 10.1126/scisignal.abh1083

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    science.org/doi/10.1126/scisignal.abh1083
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of CAR-T cells specifically targeting cancer stem cell antigen DNAJB8 against solid tumours
    1
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      RRID:CVCL_0004

      DOI: 10.1038/s41416-022-02100-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977765/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain
    1
    1. scibot 12 Jan 2023
      RRID:CVCL_0004

      DOI: 10.1158/1535-7163.MCT-21-0552

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    ncbi.nlm.nih.gov/pmc/articles/PMC9377753/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modified manufacturing process modulates CD19CAR T-cell engraftment fitness and leukemia-free survival in pediatric and young adult subjects
    1
    1. scibot 06 Jan 2023
      RRID:CVCL_0004

      DOI: 10.1158/2326-6066.CIR-21-0501

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    ncbi.nlm.nih.gov/pmc/articles/PMC9250626/
  90. www.sciencedirect.com www.sciencedirect.com
    Indoxyl sulfate impairs erythropoiesis at BFU-E stage in chronic kidney disease
    1
    1. scibot 04 Jan 2023
      RRID:CVCL_0004

      DOI: 10.1016/j.cellsig.2022.110583

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  91. Dec 2022
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genetically engineered, stem-cell-derived cellular vaccine
    1
    1. scibot 08 Dec 2022
      CCL-243

      DOI: 10.1016/j.xcrm.2022.100843

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    ncbi.nlm.nih.gov/pmc/articles/PMC9727836/
  93. www.mdpi.com www.mdpi.com
    The Microalga Skeletonema marinoi Induces Apoptosis and DNA Damage in K562 Cell Line by Modulating NADPH Oxidase
    1
    1. scibot 08 Dec 2022
      RRID:CVCL_0004

      DOI: 10.3390/molecules27238270

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    mdpi.com/1420-3049/27/23/8270
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-throughput proteomics of nanogram-scale samples with Zeno SWATH MS
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      RRID:CVCL_0004

      DOI: 10.7554/eLife.83947

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    ncbi.nlm.nih.gov/pmc/articles/PMC9711518/
  95. Nov 2022
  96. www.sciencedirect.com www.sciencedirect.com
    Profiling lariat intermediates reveals genetic determinants of early and late co-transcriptional splicing
    1
    1. scibot 29 Nov 2022
      CCL-243

      DOI: 10.1016/j.molcel.2022.11.004

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    sciencedirect.com/science/article/pii/S1097276522010668
  97. www.nature.com www.nature.com
    A nascent peptide code for translational control of mRNA stability in human cells
    1
    1. scibot 15 Nov 2022
      RRID:CVCL_0004

      DOI: 10.1038/s41467-022-34664-0

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  98. Oct 2022
  99. www.sciencedirect.com www.sciencedirect.com
    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
    1
    1. scibot 23 Oct 2022
      10243

      DOI: 10.1016/j.chembiol.2022.10.001

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    sciencedirect.com/science/article/pii/S2451945622003555
  100. www.sciencedirect.com www.sciencedirect.com
    GPC3-Unc5 receptor complex structure and role in cell migration
    1
    1. scibot 18 Oct 2022
      RRID:CVCL_0004

      DOI: 10.1016/j.cell.2022.09.025

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  101. www.sciencedirect.com www.sciencedirect.com
    MCL-1 is a master regulator of cancer dependency on fatty acid oxidation
    1
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      Cat #CCL-243

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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient and reversible Cas13d-mediated knockdown with an all-in-one lentivirus-vector
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  103. Sep 2022
  104. www.sciencedirect.com www.sciencedirect.com
    CDK12 regulates co-transcriptional splicing and RNA turnover in human cells
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    Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS
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  107. Aug 2022
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells
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    Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species
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    The BASP1 transcriptional corepressor modifies chromatin through lipid-dependent and lipid-independent mechanisms
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  111. www.sciencedirect.com www.sciencedirect.com
    Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes
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  112. Jul 2022
  113. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Randomized multicenter phase II trial of prophylactic irradiation of para-aortic lymph nodes in advanced cervical cancer according to tumor hypoxia: Korean Radiation Oncology Group (KROG 07-01) study
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  114. www.sciencedirect.com www.sciencedirect.com
    Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide expression and methylation analyses reveal aberrant cell adhesion signaling in tyrosine kinase inhibitor-resistant CML cells
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  116. Jun 2022
  117. 52.53.155.43 52.53.155.43
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    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Simple and Robust Single-Step Method for CAR-Vδ1 γδT Cell Expansion and Transduction for Cancer Immunotherapy
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  120. www.sciencedirect.com www.sciencedirect.com
    Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes
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  121. May 2022
  122. aacrjournals.org aacrjournals.org
    Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors
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  123. www.sciencedirect.com www.sciencedirect.com
    Trafficking and persistence of alloantigen-specific chimeric antigen receptor regulatory T cells in Cynomolgus macaque
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      ATCCCCL-243

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  124. www.tandfonline.com www.tandfonline.com
    JMJD1C-regulated lipid synthesis contributes to the maintenance of MLL-rearranged acute myeloid leukemia
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  125. www.tandfonline.com www.tandfonline.com
    Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade
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      RRID:CVCL_0004

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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
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  127. Apr 2022
  128. www.tandfonline.com www.tandfonline.com
    Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockade of inhibitory killer cell immunoglobulin-like receptors and IL-2 triggering reverses the functional hypoactivity of tumor-derived NK-cells in glioblastomas
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment
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    Modular design of synthetic receptors for programmed gene regulation in cell therapies
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    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
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    Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
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  134. aacrjournals.org aacrjournals.org
    EBV infection in epithelial malignancies induces resistance to antitumor natural killer cells via F3-mediated platelet aggregation
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  135. academic.oup.com academic.oup.com
    RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history
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    academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkac054/6543614
  136. www.cell.com www.cell.com
    Facile discovery of surrogate cytokine agonists
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  137. www.nature.com www.nature.com
    Transcriptome-wide identification of RNA-binding protein binding sites using seCLIP-seq
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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced NK Cell Cytotoxicity by Papillomatosis-Derived TGF-β Contributing to Low-Risk HPV Persistence in JORRP Patients
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  139. Mar 2022
  140. www.sciencedirect.com www.sciencedirect.com
    High-throughput characterization of the role of non-B DNA motifs on promoter function
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  141. link.springer.com link.springer.com
    Tumour cell-activated platelets modulate the immunological activity of CD4+, CD8+, and NK cells, which is efficiently antagonized by heparin
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SHP-1 activity by PKC-θ regulates NK cell activation threshold and cytotoxicity
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A test of the pioneer factor hypothesis using ectopic liver gene activation
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Lateral Sclerosis
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  145. Feb 2022
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunomodulatory potential of in vivo natural killer T (NKT) activation by NKTT320 in Mauritian-origin cynomolgus macaques
    1
    1. scibot 23 Feb 2022
      RRID:CVCL_0004

      DOI: 10.1016/j.isci.2022.103889

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    ncbi.nlm.nih.gov/pmc/articles/PMC8866157/
  147. www.sciencedirect.com www.sciencedirect.com
    Gene architecture directs splicing outcome in separate nuclear spatial regions
    1
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      RRID:CVCL_0004

      DOI: 10.1016/j.molcel.2022.02.001

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    sciencedirect.com/science/article/pii/S109727652200106X
  148. www.nature.com www.nature.com
    Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture
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      RRID:CVCL_0004

      DOI: 10.1038/s41596-021-00651-w

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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The E3 protein ubiquitin ligase Itch is a potential target in myeloid malignancies with marrow fibrosis
    1
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      RRID:CVCL_0004

      DOI: 10.21037/tcr-20-3115

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  150. www.nature.com www.nature.com
    Efficient recovery of potent tumour-infiltrating lymphocytes through quantitative immunomagnetic cell sorting
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      DOI: 10.1038/s41551-021-00820-y

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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a Novel Anti-CD19 CAR Containing a Fully Human scFv and Three Costimulatory Domains
    1
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      CVCL_0004

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    ncbi.nlm.nih.gov/pmc/articles/PMC8804167/
  152. www.sciencedirect.com www.sciencedirect.com
    An oncogenic enhancer encodes selective selenium dependency in AML
    1
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      ATCCCCL-243

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    sciencedirect.com/science/article/pii/S1934590922000030
  153. Jan 2022
  154. link.springer.com link.springer.com
    Novel inhibitor of hematopoietic cell kinase as a potential therapeutic agent for acute myeloid leukemia
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      DOI: 10.1007/s00262-021-03111-2

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  155. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
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  156. www.sciencedirect.com www.sciencedirect.com
    Identification and functional characterization of transcriptional activators in human cells
    1
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  157. Dec 2021
  158. www.sciencedirect.com www.sciencedirect.com
    Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity
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  159. www.sciencedirect.com www.sciencedirect.com
    HLA-A∗02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-Tumor Activity of Expanded PBMC-Derived NK Cells by Feeder-Free Protocol in Ovarian Cancer
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  161. Nov 2021
  162. www.sciencedirect.com www.sciencedirect.com
    Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
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  163. mct.aacrjournals.org mct.aacrjournals.org
    SAGE1: a Potential Target Antigen for Lung Cancer T-Cell Immunotherapy
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      DOI: 10.1158/1535-7163.MCT-21-0203

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  164. www.sciencedirect.com www.sciencedirect.com
    Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy
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      CCL-243

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  165. www.nature.com www.nature.com
    AKIRIN2 controls the nuclear import of proteasomes in vertebrates
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  166. Oct 2021
  167. www.sciencedirect.com www.sciencedirect.com
    Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications
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      CCL-243

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  168. www.sciencedirect.com www.sciencedirect.com
    NKG2A expression identifies a subset of human Vδ2 T cells exerting the highest antitumor effector functions
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      CCL-243

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  169. www.sciencedirect.com www.sciencedirect.com
    Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates
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      CCL-243

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    sciencedirect.com/science/article/pii/S1097276521007735
  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines
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      CVCL_0004

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    ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD34+ progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rgnull mice
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      RRID:CVCL_0004

      DOI: 10.1080/2162402X.2021.1981049

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    ncbi.nlm.nih.gov/pmc/articles/PMC8489932/
  172. Sep 2021
  173. www.sciencedirect.com www.sciencedirect.com
    Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
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    1. scibot 22 Sep 2021
      RRID:CVCL_0004

      DOI: 10.1016/j.celrep.2021.109725

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    sciencedirect.com/science/article/pii/S2211124721011748
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lentiviral-driven discovery of cancer drug resistance mutations
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      RRID:CVCL_0004

      DOI: 10.1158/0008-5472.CAN-21-1153

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    ncbi.nlm.nih.gov/pmc/articles/PMC8448967/
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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      RRID:CVCL_0004

      DOI: 10.7554/eLife.69142

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    ncbi.nlm.nih.gov/pmc/articles/PMC8423448/
  176. www.sciencedirect.com www.sciencedirect.com
    High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
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      CCL-243

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  177. www.sciencedirect.com www.sciencedirect.com
    Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
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      CCL-243

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  178. www.sciencedirect.com www.sciencedirect.com
    A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
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    sciencedirect.com/science/article/pii/S2451945621003937
  179. Aug 2021
  180. www.sciencedirect.com www.sciencedirect.com
    fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins
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      CCL-243

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  181. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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    elifesciences.org/articles/64148
  182. www.sciencedirect.com www.sciencedirect.com
    Methylation of dual-specificity phosphatase 4 controls cell differentiation
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.stem.2019.02.019

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  184. www.sciencedirect.com www.sciencedirect.com
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  185. www.tandfonline.com www.tandfonline.com
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  186. www.sciencedirect.com www.sciencedirect.com
    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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      CCL-243

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  187. www.sciencedirect.com www.sciencedirect.com
    Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation
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    Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia
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    A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response
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    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
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      CCL-243

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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  192. www.sciencedirect.com www.sciencedirect.com
    A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates
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    sciencedirect.com/science/article/pii/S2211124718316073
  193. www.nature.com www.nature.com
    A plate-based single-cell ATAC-seq workflow for fast and robust profiling of chromatin accessibility
    1
    1. scibot 03 Aug 2021
      RRID:CVCL_0004

      DOI: 10.1038/s41596-021-00583-5

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    nature.com/articles/s41596-021-00583-5
  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Counteracting the effect of leukemia exosomes by antiangiogenic gold nanoparticles
    1
    1. scibot 01 Aug 2021
      RRID:CVCL_0004

      DOI: 10.2147/IJN.S215711

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    ncbi.nlm.nih.gov/pmc/articles/PMC6716571/
  195. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Small Molecular Modulators of JMJD1C Preferentially Inhibit Growth of Leukemia Cells
    1
    1. scibot 01 Aug 2021
      RRID:CVCL_0004

      DOI: 10.1002/ijc.32552

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    onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32552
  196. Jul 2021
  197. www.sciencedirect.com www.sciencedirect.com
    A BRD4-mediated elongation control point primes transcribing RNA polymerase II for 3′-processing and termination
    1
    1. scibot 31 Jul 2021
      CCL-243

      DOI: 10.1016/j.molcel.2021.06.026

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    sciencedirect.com/science/article/pii/S1097276521005062
  198. www.sciencedirect.com www.sciencedirect.com
    Splicing Kinetics and Coordination Revealed by Direct Nascent RNA Sequencing through Nanopores
    1
    1. scibot 31 Jul 2021
      Human K562 cells

      DOI: 10.1016/j.molcel.2019.11.017

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    sciencedirect.com/science/article/pii/S1097276519308652
  199. www.sciencedirect.com www.sciencedirect.com
    A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia
    1
    1. scibot 31 Jul 2021
      Human: K562

      DOI: 10.1016/j.ccell.2019.11.001

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    sciencedirect.com/science/article/pii/S1535610819305215
  200. www.sciencedirect.com www.sciencedirect.com
    A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
    1
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      K562

      DOI: 10.1016/j.cell.2019.10.032

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    sciencedirect.com/science/article/pii/S0092867419311821
  201. www.nature.com www.nature.com
    A kinase-independent role for CDK8 in BCR-ABL1 + leukemia
    1
    1. scibot 31 Jul 2021
      ATCC no. CCL-243

      DOI: 10.1038/s41467-019-12656-x

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    nature.com/articles/s41467-019-12656-x
  202. elifesciences.org elifesciences.org
    Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
    1
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      RRID:CVCL_0004

      DOI: 10.7554/eLife.19760

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    elifesciences.org/articles/19760
  203. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 31 Jul 2021
      RRID:CVCL_0004

      DOI: 10.1016/j.stem.2019.02.019

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    sciencedirect.com/science/article/pii/S1934590919300712
  204. www.sciencedirect.com www.sciencedirect.com
    Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons
    1
    1. scibot 30 Jul 2021
      RRID: CVCL_0004

      DOI: 10.1016/j.cell.2019.12.014

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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity
    1
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      RRID:CVCL_0004

      DOI: 10.7554/eLife.50036

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    ncbi.nlm.nih.gov/pmc/articles/PMC6897534/
  206. www.sciencedirect.com www.sciencedirect.com
    Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer
    1
    1. scibot 30 Jul 2021
      Human chronic myelogenous leukemia cancer cell line K562

      DOI: 10.1016/j.stem.2019.08.004

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  207. www.sciencedirect.com www.sciencedirect.com
    Chemical Cross-Linking Enables Drafting ClpXP Proximity Maps and Taking Snapshots of In Situ Interaction Networks
    1
    1. scibot 30 Jul 2021
      RRID:CVCL_0004

      DOI: 10.1016/j.chembiol.2018.10.007

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  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription
    1
    1. scibot 29 Jul 2021
      Human: K562 Cells

      DOI: 10.1016/j.cell.2019.06.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC6760001/
  209. www.tandfonline.com www.tandfonline.com
    Caprine herpesvirus 1 (CpHV-1) as a potential candidate for oncolytic virotherapy
    1
    1. scibot 28 Jul 2021
      RRID:CVCL_0004

      DOI: 10.1080/15384047.2018.1504722

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    tandfonline.com/doi/full/10.1080/15384047.2018.1504722
  210. www.sciencedirect.com www.sciencedirect.com
    Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1
    1
    1. scibot 28 Jul 2021
      K562

      DOI: 10.1016/j.immuni.2019.05.005

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  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hair follicle epidermal stem cells define a niche for tactile sensation
    1
    1. scibot 28 Jul 2021
      JCRB0019

      DOI: 10.7554/eLife.38883

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    ncbi.nlm.nih.gov/pmc/articles/PMC6226291/
  212. elifesciences.org elifesciences.org
    Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2
    1
    1. scibot 28 Jul 2021
      CVCL_0004

      DOI: 10.7554/eLife.35738

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    elifesciences.org/articles/35738
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    γ-Protocadherin structural diversity and functional implications
    2
    1. scibot 28 Jul 2021
      CVCL_0004

      DOI: 10.7554/eLife.20930

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      CVCL_0004

      DOI: 10.7554/eLife.20930

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    ncbi.nlm.nih.gov/pmc/articles/PMC5106212/
  214. www.sciencedirect.com www.sciencedirect.com
    Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2
    1
    1. scibot 27 Jul 2021
      CCL-243

      DOI: 10.1016/j.chembiol.2018.10.009

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    sciencedirect.com/science/article/pii/S2451945618303428
  215. www.sciencedirect.com www.sciencedirect.com
    ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
    1
    1. scibot 27 Jul 2021
      CCL-243

      DOI: 10.1016/j.ccell.2018.02.002

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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New library construction method for single-cell genomes
    1
    1. scibot 27 Jul 2021
      K562

      DOI: 10.1371/journal.pone.0181163

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    ncbi.nlm.nih.gov/pmc/articles/PMC5517011/
  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthesis and anticancer activity of novel quinazolinone-based rhodanines
    1
    1. scibot 27 Jul 2021
      K-562

      DOI: 10.1186/s13065-017-0333-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC5640562/
  218. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
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    1. scibot 22 Jul 2021
      RRID: CVCL_0004

      DOI: 10.1016/j.ccell.2021.06.016

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    sciencedirect.com/science/article/pii/S153561082100338X
  219. www.sciencedirect.com www.sciencedirect.com
    BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells
    1
    1. scibot 14 Jul 2021
      CCL-243

      DOI: 10.1016/j.celrep.2021.109359

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    sciencedirect.com/science/article/pii/S2211124721007579
  220. link.springer.com link.springer.com
    The contrast agent 2,3,5-triiodobenzoic acid (TIBA) induces cell death in tumor cells through the generation of reactive oxygen species
    1
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      RRID:CVCL_0004

      DOI: 10.1007/s11033-021-06524-5

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    link.springer.com/article/10.1007/s11033-021-06524-5
  221. Jun 2021
  222. www.sciencedirect.com www.sciencedirect.com
    Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo
    1
    1. scibot 19 Jun 2021
      ACC 10

      DOI: 10.1016/j.molcel.2021.05.028

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    sciencedirect.com/science/article/pii/S109727652100441X
  223. jitc.bmj.com jitc.bmj.com
    T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia
    1
    1. scibot 15 Jun 2021
      CCL-243

      DOI: 10.1136/jitc-2021-002509

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    jitc.bmj.com/content/9/5/e002509
  224. www.sciencedirect.com www.sciencedirect.com
    ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells
    1
    1. scibot 08 Jun 2021
      RRID:CVCL_0004

      DOI: 10.1016/j.exphem.2021.05.006

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    sciencedirect.com/science/article/pii/S0301472X21001995
  225. www.sciencedirect.com www.sciencedirect.com
    ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia
    1
    1. scibot 03 Jun 2021
      CCL243

      DOI: 10.1016/j.molcel.2021.05.008

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  226. May 2021
  227. www.nature.com www.nature.com
    BAR-Seq clonal tracking of gene-edited cells
    1
    1. scibot 29 May 2021
      RRID:CVCL_0004

      DOI: 10.1038/s41596-021-00529-x

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  228. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ethanol Enhances Hyperthermia-Induced Cell Death in Human Leukemia Cells
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      CVCL_0004

      DOI: 10.3390/ijms22094948

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    ncbi.nlm.nih.gov/pmc/articles/PMC8125413/
  229. www.sciencedirect.com www.sciencedirect.com
    SeqStain is an efficient method for multiplexed, spatialomic profiling of human and murine tissues
    1
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      CCL-243

      DOI: 10.1016/j.crmeth.2021.100006

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    sciencedirect.com/science/article/pii/S2667237521000060
  230. www.sciencedirect.com www.sciencedirect.com
    Small RNAs are modified with N-glycans and displayed on the surface of living cells
    1
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      CCL-243

      DOI: 10.1016/j.cell.2021.04.023

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    sciencedirect.com/science/article/pii/S0092867421005031
  231. www.sciencedirect.com www.sciencedirect.com
    Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity
    1
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      CCL-243

      DOI: 10.1016/j.immuni.2020.05.001

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    sciencedirect.com/science/article/pii/S1074761320301825
  232. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
    1
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      RRID:CVCL_0004

      DOI: 10.1016/j.cell.2021.04.016

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    sciencedirect.com/science/article/pii/S0092867421004955
  233. www.sciencedirect.com www.sciencedirect.com
    Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors
    1
    1. scibot 09 May 2021
      RRID:CVCL_0004

      DOI: 10.1016/j.stem.2020.04.005

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