173 Matching Annotations
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    IRE1α-XBP1s axis is required for BCG-induced trained immunity against viral infection by inhibiting AHR signaling
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    biorxiv.org/content/10.1101/2025.08.21.671435v1
  3. Aug 2025
  4. 52.53.155.43 52.53.155.43
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    SUCLG1 deficiency-induced histone succinylation impairs oncogene expression in acute myeloid leukemia
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    Investigating the relationship Between AMBRA1 and Cell Proliferation in Melanoma
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    Pharmacodynamic analyses of LAT1 inhibitors in vitro and in vivo by targeted metabolomics reveal target-independent effects
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    sciencedirect.com/science/article/pii/S0753332225005967
  8. Jul 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modular DNA barcoding of nanobodies enables multiplexed in situ protein imaging and high-throughput biomolecule detection
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  11. Jun 2025
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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  15. May 2025
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    Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells
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    CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models
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    Spns2-dependent S1P Transport as a Therapeutic Target
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    The m5C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism
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  20. Apr 2025
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    Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma
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    Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles
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    Augmenting CAR T Cell Functions with LIGHT
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  24. Mar 2025
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    A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies
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    BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway
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    Synergistic effects of HO-1 inhibition and chemotherapy on tumor proliferation and immune infiltration: An in vitro and in vivo approach to enhancing prostate cancer treatment
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  28. Feb 2025
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    Pharmacological rescue of mutant p53 triggers spontaneous tumor regression via immune responses
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    Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation
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    MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK
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    An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities
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  35. Jan 2025
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    Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells
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    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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  39. Dec 2024
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    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
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    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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  45. Nov 2024
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    Schwann cell C5aR1 co-opts inflammasome NLRP1 to sustain pain in a mouse model of endometriosis
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  48. Oct 2024
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  50. Sep 2024
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  53. Aug 2024
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    The Microenvironment of Solid Tumors: Components and Current Challenges of Tumor-on-a-Chip Models
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    The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization
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  59. Jul 2024
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    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
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    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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    The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells
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  65. Jun 2024
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    β-Carboline derivatives are potent against Acute Myeloid Leukemia in vitro and in vivo
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    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
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    Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
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  70. May 2024
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    LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition
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  74. Apr 2024
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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    Acquired immune resistance is associated with interferon signature and modulation of KLF6/c-MYB transcription factors in myeloid leukemia
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    The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling
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  78. Feb 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
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    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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  83. Jan 2024
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    An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo
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    Non-IL-2-blocking anti-CD25 antibody inhibits tumor growth by depleting Tregs and has synergistic effects with anti-CTLA-4 therapy
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    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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  88. Nov 2023
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    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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  90. Oct 2023
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    Hypoxia-driven protease legumain promotes immunosuppression in glioblastoma
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    Blocking oligomerization is the most viable strategy to inhibit STING
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    Cooperative CAR targeting to selectively eliminate AML and minimize escape
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    A novel label-free, pre-equilibrium assay to determine the association and dissociation rate constants of therapeutic antibodies on living cells
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  95. Aug 2023
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    Discovery of a novel marker for human granulocytes and tissue macrophages: RTL1 revisited
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    TSC22D3 as an immune-related prognostic biomarker for acute myeloid leukemia
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  98. Jul 2023
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    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
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  100. Jun 2023
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    The antitumor effects of WNT5A against hematological malignancies
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    link.springer.com/article/10.1007/s12079-023-00773-8
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization
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    ncbi.nlm.nih.gov/pmc/articles/PMC10236204/
  103. May 2023
  104. www.pnas.org www.pnas.org
    A genome-wide optical pooled screen reveals regulators of cellular antiviral responses
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    pnas.org/doi/abs/10.1073/pnas.2210623120
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    A PCR protocol to establish standards for routine mycoplasma testing that by design detects over ninety percent of all known mycoplasma species
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    Discovery of two new isoforms of the human DUT gene
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    link.springer.com/article/10.1038/s41598-023-32970-1
  107. Apr 2023
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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  109. Mar 2023
  110. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  224. www.sciencedirect.com www.sciencedirect.com
    NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation
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    sciencedirect.com/science/article/pii/S1097276517306147
  225. www.jbc.org www.jbc.org
    Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a
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  227. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC7360335/