86 Matching Annotations
  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    Anti–B-cell maturation antigen chimeric antigen receptor T-cell therapy bb21217 for relapsed and refractory multiple myeloma: results from the phase 1 CRB-402 study
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    aacrjournals.org/cancerimmunolres/article/14/4/528/776517/Anti-B-cell-Maturation-Antigen-Chimeric-Antigen
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13073330/
  5. 54.241.53.176 54.241.53.176
    A Fully Human Pan VL9 HLAE TCRm Antibody Enables Functional Dissection of HLAE Biology and Checkpoint Signaling
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    54.241.53.176/089c0d54aafa939862e15036a250ae2fa17f1db6/1-s2.0-S2589004226010448-main-html.html
  6. www.sciencedirect.com www.sciencedirect.com
    A novel small-molecule inhibitor of IRF4 selectively suppresses multiple myeloma
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    sciencedirect.com/science/article/pii/S2352304226001480
  7. Feb 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-myeloma activity of the CXCR4 antagonist WZ811
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    pmc.ncbi.nlm.nih.gov/articles/PMC12913330/
  9. www.sciencedirect.com www.sciencedirect.com
    Targeting BCMA in multiple myeloma with a trifunctional NK cell engager
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    sciencedirect.com/science/article/pii/S2666379126000455
  10. www.sciencedirect.com www.sciencedirect.com
    APRIL-driven BCMA/TACI dual-targeted ligand–drug conjugates for selective and potent therapy of multiple myeloma
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    sciencedirect.com/science/article/pii/S2211383526001012
  11. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD-L1 and T Cell Senescence
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202506239
  12. Jan 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A High-Fiber Plant-Based Diet in Myeloma Precursor Disorders – Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12811828/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision radiolabeled B-cell maturation nanobody for targeted PET imaging and radioligand therapy of disseminated multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12775650/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL
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    pmc.ncbi.nlm.nih.gov/articles/PMC12795454/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clostridium butyricum alleviates multiple myeloma by remodeling the bone marrow microenvironment and inhibiting PI3K/AKT pathway through the gut‒bone axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12773645/
  17. www.tandfonline.com www.tandfonline.com
    Clostridium butyricum alleviates multiple myeloma by remodeling the bone marrow microenvironment and inhibiting PI3K/AKT pathway through the gut‒bone axis
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    tandfonline.com/doi/abs/10.1080/19490976.2025.2609455
  18. Nov 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting of the CD161 Inhibitory Receptor Enhances Bone‐Marrow‐Resident Memory CD8+ T‐Cell‐Mediated Immunity against Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12622403/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic potential of PRMT1 as a critical survival dependency target in multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12584455/
  21. Sep 2025
  22. www.sciencedirect.com www.sciencedirect.com
    Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens
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    sciencedirect.com/science/article/pii/S0092867425010323
  23. Aug 2025
  24. www.sciencedirect.com www.sciencedirect.com
    Cinobufagin overcomes bortezomib resistance in multiple myeloma strains by targeting SEC62/TRPM4-mediated NECSO
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    sciencedirect.com/science/article/pii/S0944711325008104
  25. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Self-Assembling Multi-Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.202502156
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314523/
  27. Jul 2025
  28. 52.53.155.43 52.53.155.43
    cir-23-0692-html.html
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  29. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A somatic multiple myeloma mutation unravels a mechanism of oligomerization-mediated product inhibition in GGPPS
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70181
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  31. Jun 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12161464/
  33. 52.53.155.43 52.53.155.43
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  34. www.sciencedirect.com www.sciencedirect.com
    Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling
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    sciencedirect.com/science/article/pii/S153561082500220X
  35. May 2025
  36. www.sciencedirect.com www.sciencedirect.com
    Enhancing plasmacytoid dendritic cell functionality with all-trans retinoic acid for improved multiple myeloma therapy
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    sciencedirect.com/science/article/pii/S295032992500061X
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048002/
  38. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70071
  39. www.sciencedirect.com www.sciencedirect.com
    HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma
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    sciencedirect.com/science/article/pii/S2211124725004917
  40. Apr 2025
  41. 52.53.155.43 52.53.155.43
    Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma
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    52.53.155.43/5480965c1766ce5dc1f2ceec9f18c523a1b9a8ab/2024.10.22.617161.full-html.html
  42. www.nature.com www.nature.com
    The butyrate derived from probiotic Clostridium butyricum exhibits an inhibitory effect on multiple myeloma through cell death induction
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    nature.com/articles/s41598-025-97038-8
  43. 52.53.155.43 52.53.155.43
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  44. Mar 2025
  45. www.sciencedirect.com www.sciencedirect.com
    Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity
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    sciencedirect.com/science/article/pii/S0898656825001809
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11897230/
  47. Feb 2025
  48. www.cell.com www.cell.com
    EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models
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    cell.com/cancer-cell/abstract/S1535-6108(25)00031-5
  49. Jan 2025
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets
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    pmc.ncbi.nlm.nih.gov/articles/PMC11866523/
  51. Dec 2024
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer effect of minor phytocannabinoids in preclinical models of multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11627469/
  53. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  54. Aug 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple mechanisms contribute to acquired TRAIL resistance in multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299348/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292198/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  58. Jul 2024
  59. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    sciencedirect.com/science/article/pii/S1535610824002174
  60. www.sciencedirect.com www.sciencedirect.com
    Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death
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    sciencedirect.com/science/article/pii/S2211124724007745
  61. 52.53.155.43 52.53.155.43
    cir-23-0692-html.html
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11217734/
  63. Jun 2024
  64. www.mdpi.com www.mdpi.com
    Preclinical Evaluation of a Novel Series of Polyfluorinated Thalidomide Analogs in Drug-Resistant Multiple Myeloma
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    mdpi.com/2218-273X/14/6/725
  65. May 2024
  66. www.sciencedirect.com www.sciencedirect.com
    Protocol for cytoskeleton staining of the semi-adherent multiple myeloma cell line RPMI 8226 by immunofluorescence
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    sciencedirect.com/science/article/pii/S2666166724002259
  67. 52.53.155.43 52.53.155.43
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  68. Mar 2024
  69. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synergistic integration of histone deacetylase inhibitors apparently enhances the cytokine-induced killer cell efficiency in multiple myeloma via the NKG2D pathway
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    onlinelibrary.wiley.com/doi/10.1002/cti2.1500
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfate promotes TRAIL-induced tumor cell apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10945736/
  72. Feb 2024
  73. aacrjournals.org aacrjournals.org
    Exosomal lncRNA NEAT1 inhibits NK cell activity to promote multiple myeloma cell immune escape via an EZH2/PBX1 axis
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    aacrjournals.org/mcr/article/22/2/125/733692/Exosomal-lncRNA-NEAT1-Inhibits-NK-Cell-Activity-to
  74. www.biorxiv.org www.biorxiv.org
    KDM6A Regulates Immune Response Genes in Multiple Myeloma
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    biorxiv.org/content/10.1101/2024.02.12.579179v1
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Anti-B-cell Maturation Antigen Alpha-Amanitin Antibody-drug Conjugate HDP-101 Shows Superior Activity to Belantamab Mafodotin and Enhanced Efficacy in Deletion 17p Myeloma Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802748/
  76. Jan 2024
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10825369/
  78. Dec 2023
  79. 52.53.155.43 52.53.155.43
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  80. Nov 2023
  81. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    sciencedirect.com/science/article/pii/S1535610823003665
  82. Oct 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unrevealed roles of extracellular enolase‑1 (ENO1) in promoting glycolysis and pro‑cancer activities in multiple myeloma via hypoxia‑inducible factor 1α
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    ncbi.nlm.nih.gov/pmc/articles/PMC10568254/
  84. Sep 2023
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Renieramycin T Derivative DH_22 Induces p53-dependent Apoptosis in Lung Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10500526/
  86. Jun 2023
  87. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/d5910f7dd67f30dd43075adaf622ac667e880a9d/Molecular Oncology - 2023 - Luo - The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78 BiP to induce unfolded protein-html.html
  88. May 2023
  89. link.springer.com link.springer.com
    Discovery of two new isoforms of the human DUT gene
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    link.springer.com/article/10.1038/s41598-023-32970-1
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    miR‐17‐3p promotes the proliferation of multiple myeloma cells by downregulating P21 expression through LMLN inhibition
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.33528
  91. Apr 2023
  92. www.biorxiv.org www.biorxiv.org
    A core Nrf2 gene set defined through comprehensive transcriptomic analysis predicts drug resistance and poor multi-cancer prognosis
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    biorxiv.org/content/10.1101/2023.04.20.537691v1
  93. Jan 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377753/
  95. Sep 2022
  96. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722012694
  97. Aug 2022
  98. www.sciencedirect.com www.sciencedirect.com
    Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
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    sciencedirect.com/science/article/pii/S1535610822003579
  99. Oct 2021
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
  101. Aug 2021
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5517637/
  103. Jul 2021
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromothripsis in Treatment Resistance in Multiple Myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC5637343/
  105. May 2021
  106. www.sciencedirect.com www.sciencedirect.com
    Sensitive intranuclear flow cytometric quantification of IRF4 protein in multiple myeloma and normal human hematopoietic cells
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    sciencedirect.com/science/article/pii/S2666166721002720
  107. www.nature.com www.nature.com
    JunB is a key regulator of multiple myeloma bone marrow angiogenesis
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    nature.com/articles/s41375-021-01271-9
  108. www.sciencedirect.com www.sciencedirect.com
    Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
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    sciencedirect.com/science/article/pii/S1097276521003208
  109. www.sciencedirect.com www.sciencedirect.com
    Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption
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    sciencedirect.com/science/article/pii/S1934590920306019
  110. Apr 2021
  111. www.sciencedirect.com www.sciencedirect.com
    Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I
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    sciencedirect.com/science/article/pii/S2451945620302853
  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oxidatively modified low‐density lipoproteins are potential mediators of proteasome inhibitor resistance in multiple myeloma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33497
  113. Feb 2021
  114. www.sciencedirect.com www.sciencedirect.com
    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
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    sciencedirect.com/science/article/pii/S1097276520309886
  115. Dec 2020
  116. www.nature.com www.nature.com
    Modulating proteasome inhibitor tolerance in multiple myeloma: an alternative strategy to reverse inevitable resistance
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    nature.com/articles/s41416-020-01191-y
  117. Sep 2020
  118. www.sciencedirect.com www.sciencedirect.com
    The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis
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    sciencedirect.com/science/article/pii/S2211124720311517
  119. elifesciences.org elifesciences.org
    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
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    elifesciences.org/articles/44161
  120. Jan 2020
  121. www.sciencedirect.com www.sciencedirect.com
    Regulation of Autophagic Flux by the 20S Proteasome
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    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    elifesciences.org/articles/47084
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  124. Nov 2018
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    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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