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202 Matching Annotations

Oct 2025
www.sciencedirect.com www.sciencedirect.com

Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors

1
1. scibot 01 Oct 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.chembiol.2025.09.003
  
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sciencedirect.com/science/article/pii/S2451945625002685
Sep 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Self-Propelled Magnetic Micromotor-Functionalized DNA Tile System for Autonomous Capture of Circulating Tumor Cells in Clinical Diagnostics

1
1. scibot 18 Sep 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1002/advs.202508636
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202508636
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PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis

1
1. scibot 17 Sep 2025
  
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  ATCC HTB-30
  
  DOI: 10.1016/j.xcrm.2025.102356
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S266637912500429X
Aug 2025
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Suppression of mTOR Signaling by miR-302/367 Cluster in Breast Cancer Cells

1
1. scibot 21 Aug 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1096/fj.202501582R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202501582R
www.tandfonline.com www.tandfonline.com

EpCAM-targeted near-infrared photoimmunotherapy (NIR-PIT) for the treatment of breast cancer

3
1. scibot 20 Aug 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1080/07853890.2025.2540599
  
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2. scibot 20 Aug 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1080/07853890.2025.2540599
  
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3. scibot 16 Aug 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1080/07853890.2025.2540599
  
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tandfonline.com/doi/full/10.1080/07853890.2025.2540599
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Building simplified cancer subtyping and prediction models with glycan gene signatures

1
1. scibot 12 Aug 2025
  
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  DSMZACC 736
  
  DOI: 10.1016/j.crmeth.2025.101140
  
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sciencedirect.com/science/article/pii/S2667237525001766
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression

1
1. scibot 01 Aug 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.3892/ol.2025.15192
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12308457/
Jul 2025
www.mdpi.com www.mdpi.com

ERRα and HIF-1α Cooperate to Enhance Breast Cancer Aggressiveness and Chemoresistance Under Hypoxic Conditions

1
1. scibot 22 Jul 2025
  
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  RRID: CVCL_0033
  
  DOI: 10.3390/cancers17142382
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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mdpi.com/2072-6694/17/14/2382
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tuning antibody stability and function by rational designs of framework mutations

1
1. scibot 19 Jul 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1080/19420862.2025.2532117
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12269682/
www.biorxiv.org www.biorxiv.org

An Enhancement of Extrachromosomal Circular DNA Enrichment and Amplification to Address the Extreme Low Overlap Between Replicates

1
1. scibot 08 Jul 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1101/2025.06.28.662146
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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biorxiv.org/content/10.1101/2025.06.28.662146v1
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Effectorless Fc-fusion improves FLT3L drug-like properties for cancer immunotherapy combinations

1
1. scibot 08 Jul 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.ebiom.2025.105822
  
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sciencedirect.com/science/article/pii/S235239642500266X
aacrjournals.org aacrjournals.org

Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates

1
1. scibot 04 Jul 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1158/1535-7163.MCT-23-0622
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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aacrjournals.org/mct/article/23/4/541/741864/Development-of-a-Novel-DNA-Mono-alkylator-Platform
Jun 2025
www.tandfonline.com www.tandfonline.com

Valency-affinity mapping of multivalent liposomes for tunable target cell discrimination

1
1. scibot 28 Jun 2025
  
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  HTB-30
  
  DOI: 10.1080/10717544.2025.2512950
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @sjvitug
  
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tandfonline.com/doi/full/10.1080/10717544.2025.2512950
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia

1
1. scibot 25 Jun 2025
  
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  CVCL_0033
  
  DOI: 10.1158/2767-9764.CRC-25-0023
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
  Curator: @sonofthor
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12174973/
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 13 Jun 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1158/1535-7163.mct-24-1182
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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52.53.155.43/0787775ae914f9357d476625a7eb0db19fa88217/PDF-html.html
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 11 Jun 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1002/1878-0261.70056
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70056
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Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy

1
1. scibot 05 Jun 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.stem.2025.05.007
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S1934590925001870
May 2025
www.sciencedirect.com www.sciencedirect.com

Therapeutic targeting of circTNK2 with nanoparticles restores tamoxifen sensitivity and enhances NK cell-mediated immunity in ER-positive breast cancer

1
1. scibot 29 May 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.canlet.2025.217823
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S0304383525003908
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Assessment of the Effects of Single-Domain Anti-Idiotypic Distribution Enhancers on the Disposition of Trastuzumab and on the Efficacy of a PE24-Trastuzumab Immunotoxin

1
1. scibot 21 May 2025
  
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  CVCL_0033
  
  DOI: 10.3390/cancers17091468
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12071152/
link.springer.com link.springer.com

Microtubule associated serine/threonine kinase-3 inhibits the malignant phenotype of breast cancer by promoting phosphorylation-mediated ubiquitination degradation of yes-associated protein

1
1. scibot 21 May 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1186/s13058-025-02028-3
  
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link.springer.com/article/10.1186/s13058-025-02028-3
link.springer.com link.springer.com

A fermented Mistletoe (Viscum album L.) extract elicits markers characteristic for immunogenic cell death driven by endoplasmic reticulum stress in vitro

1
1. scibot 21 May 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1186/s12906-025-04909-8
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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link.springer.com/article/10.1186/s12906-025-04909-8
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

GRB2 Promotes Malignant Behaviors of Breast Cancer by Modulating the Global Expression and Alternative Splicing Profiles in SK‐BR‐3 Cells Through Binding mRNA

1
1. scibot 21 May 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1002/cam4.70905
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12086363/
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Sumoylated Etv1 establishes mouse mammary cancer stem cells that support tumorigenesis by non-stem cancer cells

1
1. scibot 16 May 2025
  
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  ATCCHTB-30
  
  DOI: 10.1016/j.devcel.2025.04.005
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1534580725002072
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Molecular basis of β2 integrin activation by talin unveils subunit-specific mechanisms of integrin signaling

1
1. scibot 16 May 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.celrep.2025.115607
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S221112472500378X
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Ultrasensitive Detection and Monitoring of Circulating Tumor DNA Using Structural Variants in Early-Stage Breast Cancer

1
1. scibot 19 Apr 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1158/1078-0432.CCR-24-3472
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11994999/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons

1
1. scibot 04 Apr 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1158/1078-0432.CCR-24-2669
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11959274/
www.cell.com www.cell.com

SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity

1
1. scibot 02 Apr 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.celrep.2025.115476
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00247-5
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Involvement of microRNAs-449/FASN axis in response to trastuzumab therapy in HER2-positive breast cancer

1
1. scibot 28 Mar 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1186/s10020-025-01163-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11938741/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy

1
1. scibot 26 Feb 2025
  
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  RRID: CVCL_0033
  
  DOI: 10.3389/fphar.2025.1532104
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11847841/
www.sciencedirect.com www.sciencedirect.com

Potentiating anti-tumor immunity by re-engaging immune synapse molecules

1
1. scibot 25 Feb 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.xcrm.2025.101975
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2666379125000485
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 20 Feb 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1111/bph.17463
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17463
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Metabolic Profiling of Breast Cancer Cell Lines: Unique and Shared Metabolites

1
1. scibot 15 Feb 2025
  
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  CVCL_0033
  
  DOI: 10.3390/ijms26030969
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11816582/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities

1
1. scibot 15 Feb 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1186/s13046-025-03319-5
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11818027/
www.sciencedirect.com www.sciencedirect.com

Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes

1
1. scibot 14 Feb 2025
  
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  ATCC, provided by Toni Petan, Jozef Stefan Institute, IJSCat# HTB-30
  
  DOI: 10.1016/j.chembiol.2025.01.007
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S2451945625000303
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The concomitant tumor suspension cells derived from skbr-3 exhibit circulating tumor cell features

1
1. scibot 07 Feb 2025
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.tice.2025.102777
  
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sciencedirect.com/science/article/pii/S0040816625000576
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Pre-Clinical Rationale for Amcenestrant Combinations in HER2+/ER+ Breast Cancer

1
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  DOI: 10.3390/ijms26020460
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11765389/
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Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells

1
1. scibot 17 Jan 2025
  
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  DOI: 10.1002/ijc.35271
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.35271
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A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

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1. scibot 14 Jan 2025
  
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  DOI: 10.7554/eLife.93183
  
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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

1
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  ATCCCat# HTB-30
  
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sciencedirect.com/science/article/pii/S1535610824004434
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The RRP9-JUN axis promotes breast cancer progression via the AKT signalling pathway

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1. scibot 20 Dec 2024
  
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  RRID:HTB-30
  
  DOI: 10.1186/s13062-024-00578-8
  
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A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor

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B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies

1
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  CVCL_0033
  
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Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment

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  Cat#HTB-30
  
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Aberrant expression of CD14 in breast tumor cells is associated with poor outcome

1
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  RRID:CVCL_0033
  
  DOI: 10.1101/2024.11.07.622456
  
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biorxiv.org/content/10.1101/2024.11.07.622456v1
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Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition

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  DOI: 10.1016/j.xcrm.2024.101752
  
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sciencedirect.com/science/article/pii/S2666379124004828
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Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

1
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  DOI: 10.1016/j.cell.2020.02.019
  
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cell.com/cell/fulltext/S0092-8674(20)30163-X
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Adipocytes promote metastasis of breast cancer by attenuating the FOXO1 effects and regulating copper homeostasis

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  DOI: 10.1186/s12935-024-03433-y
  
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Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth

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A Tetravalent Biparatopic Antibody Causes Strong HER2 Internalization and Inhibits Cellular Proliferation

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1. scibot 02 Aug 2024
  
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  HTB30
  
  DOI: 10.3390/life11111157
  
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miR-770-5p-induced cellular switch to sensitize trastuzumab resistant breast cancer cells targeting HER2/EGFR/IGF1R bidirectional crosstalk

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  RRID:CVCL_0033
  
  DOI: 10.55730/1300-0152.2690
  
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Affimer reagents enable targeted delivery of therapeutic agents and RNA via Virus-Like Particles

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  DOI: 10.1016/j.isci.2024.110461
  
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  DOI: 10.1016/j.isci.2024.110461
  
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BPS Publications

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  DOI: 10.1111/bph.16489
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
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Define Critical Parameters of Trastuzumab-Mediated ADCC Assays via Assay Optimization Processes, Focusing on the Impact of Cryopreserved Effector Cells on Assay Performance

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  RRID:CVCL_0033
  
  DOI: 10.3390/cancers16132367
  
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mdpi.com/2072-6694/16/13/2367
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Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite

2
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Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer

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  DOI: 10.1038/s41416-024-02697-5
  
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nature.com/articles/s41416-024-02697-5
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eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer

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  RRID:CVCL_0033
  
  DOI: 10.1126/scisignal.adh4475
  
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science.org/doi/10.1126/scisignal.adh4475
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KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer

1
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  DOI: 10.3389/fonc.2024.1227151
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
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Activation of PKR by a short-hairpin RNA

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  RRID: CVCL_0033
  
  DOI: 10.1101/2024.05.08.592371
  
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Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates

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  DOI: 10.1158/1535-7163.MCT-23-0822
  
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A novel long non-coding RNA MIR4500HG003 promotes tumor metastasis through miR-483-3p-MMP9 axis in triple-negative breast cancer

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Use of Payload Binding Selectivity Enhancers to Improve Therapeutic Index of Maytansinoid-Antibody-Drug Conjugates

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ncbi.nlm.nih.gov/pmc/articles/PMC10811745/
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Type I interferon regulation by USP18 is a key vulnerability in cancer

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Cryo-EM structures reveal two allosteric inhibition modes of PI3KαH1047R involving a re-shaping of the activation loop

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cell.com/structure/fulltext/S0969-2126(24)00089-3
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An engineering strategy to target activated EGFR with CAR T cells

1
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  DOI: 10.1016/j.crmeth.2024.100728
  
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sciencedirect.com/science/article/pii/S2667237524000511
Feb 2024
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AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments

1
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  DOI: 10.1172/JCI173299
  
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Targeting TOP2B as a vulnerability in aging and aging-related diseases

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  DOI: 10.1016/j.bbadis.2024.167044
  
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SAA1-dependent reprogramming of adipocytes by tumor cells is associated with triple negative breast cancer aggressiveness

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  DOI: 10.1002/ijc.34859
  
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An estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2

1
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  DOI: 10.1186/s12935-024-03245-0
  
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SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion

1
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FEBS Press

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GRB2 is a BECN1 interacting protein that regulates autophagy.

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First evidence of AXL expression on circulating tumor cells in metastatic breast cancer patients: A proof-of-concept study

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Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer

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A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression

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Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers

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Oct 2023
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Comparison Study of Small Extracellular Vesicle Isolation Methods for Profiling Protein Biomarkers in Breast Cancer Liquid Biopsies

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FEBS Press

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52.53.155.43/dbe8c3e3fbcbeef5c4f8f35843262b8cfb5dca0c/Molecular Oncology - 2023 - Liu - USP7 reduces the level of nuclear DICER impairing DNA damage response and promoting-html.html
52.53.155.43 52.53.155.43

A novel label-free, pre-equilibrium assay to determine the association and dissociation rate constants of therapeutic antibodies on living cells

1
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52.53.155.43/898d8e74ba94791d2618a9f0837530aab54dfc5b/British J Pharmacology - 2023 - Janezic - A novel label-free pre-equilibrium assay to determine the association and-html.html
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ccr-23-0103-html.html

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NR1D1 Stimulates Antitumor Immune Responses in Breast Cancer by Activating cGAS-STING Signaling

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AMT-562, a novel HER3-targeting antibody drug conjugate, demonstrates a potential to broaden therapeutic opportunities for HER3-expressing tumors

1
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Aug 2023
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ccr-23-0103-html.html

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52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
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CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis

1
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mct-23-0198-html.html

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ccr-23-0103-html.html

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Jun 2023
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Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion

1
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Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

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How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view

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May 2023
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G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis

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  DOI: 10.18632/oncotarget.28433
  
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Adcitmer®, a new CD56-targeting MMAE-conjugated antibody is a potential therapeutic approach in Merkel cell carcinoma

1
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  DOI: 10.1111/bjd.20770
  
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onlinelibrary.wiley.com/doi/full/10.1111/bjd.20770
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In silico and experimental methods for designing a potent anticancer arazyme-herceptin fusion protein in HER2-positive breast cancer

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  DOI: 10.1007/s00894-023-05562-z
  
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link.springer.com/article/10.1007/s00894-023-05562-z
Apr 2023
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Biparatopic anti-HER2 drug radioconjugates as breast cancer theranostics

1
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  DOI: 10.1038/s41416-023-02272-4
  
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Payload-binding Fab fragments increase the therapeutic index of MMAE antibody-drug conjugates

1
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Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

1
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Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2-positive cancers

1
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  DOI: 10.1002/1878-0261.13419
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13419
Mar 2023
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Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells

1
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ncbi.nlm.nih.gov/pmc/articles/PMC10002699/
Feb 2023
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E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity

1
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  DOI: 10.1016/j.molcel.2023.01.019
  
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S100A9 promotes glycolytic activity in HER2-positive breast cancer to induce immunosuppression in the tumour microenvironment

1
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  DOI: 10.1016/j.heliyon.2023.e13294
  
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Jan 2023
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CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

1
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Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine

1
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  DOI: 10.1158/2326-6066.CIR-21-0454
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
Oct 2022
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Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy

1
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  DOI: 10.1016/j.cmet.2022.09.021
  
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Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance

1
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  ATCCCat#HTB-30
  
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May 2022
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ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1

1
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  CVCL_0033
  
  DOI: 10.1016/j.molcel.2022.04.034
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S1097276522004348
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CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome

1
1. scibot 25 May 2022
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1186/s13058-022-01528-w
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9125938/
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8-azaadenosine and 8-chloroadenosine are not selective inhibitors of ADAR

1
1. scibot 21 May 2022
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1158/2767-9764.crc-21-0027
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9113518/
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A text-based computational framework for patient -specific modeling for classification of cancers

1
1. scibot 11 May 2022
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.isci.2022.103944
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9076893/
Apr 2022
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Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes

1
1. scibot 14 Apr 2022
  
  in Public
  
  RRID: CVCL_0033
  
  DOI: 10.1016/j.celrep.2022.110636
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2211124722003886
Mar 2022
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Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer

1
1. scibot 26 Mar 2022
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.7554/eLife.68481
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8937232/
aacrjournals.org aacrjournals.org

MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding

1
1. scibot 05 Mar 2022
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1158/2767-9764.CRC-21-0103
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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aacrjournals.org/cancerrescommun/article/2/2/110/681605/MYC-Inhibition-Halts-Metastatic-Breast-Cancer
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Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner

1
1. scibot 04 Mar 2022
  
  in Public
  
  CVCL_0033
  
  DOI: 10.1158/1541-7786.MCR-21-0219
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8419025/
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Unlabeled aspirin as an activatable theranostic MRI agent for breast cancer

1
1. scibot 04 Mar 2022
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.7150/thno.53147
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8825591/
Feb 2022
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Systematic illumination of druggable genes in cancer genomes

1
1. scibot 23 Feb 2022
  
  in Public
  
  ATCCHTB-30
  
  DOI: 10.1016/j.celrep.2022.110400
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2211124722001218
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Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity

1
1. scibot 19 Feb 2022
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.18632/oncotarget.28195
  
  Resource: (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8845119/
Jan 2022
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Metastasis enhancer PGRMC1 boosts store-operated Ca2+ entry by uncoiling Ca2+ sensor STIM1 for focal adhesion turnover and actomyosin formation

1
1. scibot 19 Jan 2022
  
  in Public
  
  ATCCCat# HTB-30
  
  DOI: 10.1016/j.celrep.2021.110281
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2211124721017964
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FTY720 in resistant human epidermal growth factor receptor 2-positive breast cancer

1
1. scibot 12 Jan 2022
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1038/s41598-021-04328-y
  
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nature.com/articles/s41598-021-04328-y
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Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness

1
1. scibot 05 Jan 2022
  
  in Public
  
  HTB-30
  
  DOI: 10.1016/j.cmet.2021.12.001
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S1550413121006203
Dec 2021
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MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells

1
1. scibot 29 Dec 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.celrep.2021.110160
  
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sciencedirect.com/science/article/pii/S2211124721016569
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Polypeptide-GalNAc-Transferase-13 Shows Prognostic Impact in Breast Cancer

1
1. scibot 01 Dec 2021
  
  in Public
  
  RRID: CVCL_0033
  
  DOI: 10.3390/cancers13225616
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8616257/
Nov 2021
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Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro

1
1. scibot 18 Nov 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.xpro.2021.100956
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2666166721006626
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GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12

1
1. scibot 09 Nov 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.isci.2021.103311
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2589004221012803
Oct 2021
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 15 Oct 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1002/2211-5463.13303
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13303
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NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer

1
1. scibot 08 Oct 2021
  
  in Public
  
  HTB-30
  
  DOI: 10.1016/j.molcel.2021.09.016
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S1097276521007504
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Preclinical and Clinical Characterization of Fibroblast-derived Neuregulin-1 on Trastuzumab and Pertuzumab Activity in HER2-positive Breast Cancer

1
1. scibot 01 Oct 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1158/1078-0432.CCR-20-2915
  
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clincancerres.aacrjournals.org/content/27/18/5096
Sep 2021
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ERα determines the chemoresistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions

1
1. scibot 24 Sep 2021
  
  in Public
  
  RRID: CVCL_0033
  
  DOI: 10.1016/j.omtn.2021.07.022
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2162253121001906
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REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps

1
1. scibot 11 Sep 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.molcel.2021.08.016
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S1097276521006833
Aug 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Primary breast cancer biomarkers based on glycosylation and extracellular vesicles detected from human serum

1
1. scibot 31 Aug 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1002/cnr2.1540
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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onlinelibrary.wiley.com/doi/full/10.1002/cnr2.1540
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Clinical Implications of Sub-grouping HER2 Positive Tumors by Amplicon Structure and Co-amplified Genes

1
1. scibot 14 Aug 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1038/s41598-019-55455-6
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6906288/
www.sciencedirect.com www.sciencedirect.com

CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.celrep.2019.11.008
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:CVCL_0033
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sciencedirect.com/science/article/pii/S2211124719314792
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Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

1
1. scibot 01 Aug 2021
  
  in Public
  
  CVCL_0033
  
  DOI: 10.1016/j.cels.2019.11.001
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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  RRIDCUR:Validated RRID:CVCL_0033
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sciencedirect.com/science/article/pii/S2405471219303874
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

1
1. scibot 30 Jul 2021
  
  in Public
  
  Human: SK-BR-3
  
  DOI: 10.1016/j.celrep.2019.08.076
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Missing RRID:CVCL_0033
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sciencedirect.com/science/article/pii/S2211124719311313
www.sciencedirect.com www.sciencedirect.com

Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

1
1. scibot 30 Jul 2021
  
  in Public
  
  SKBR3
  
  DOI: 10.1016/j.ccell.2019.08.006
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1535610819303745
www.embopress.org www.embopress.org

CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling

1
1. scibot 30 Jul 2021
  
  in Public
  
  SKBR3
  
  DOI: 10.15252/embr.201948058
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:CVCL_0033
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embopress.org/doi/10.15252/embr.201948058
www.sciencedirect.com www.sciencedirect.com

Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues

1
1. scibot 29 Jul 2021
  
  in Public
  
  SK-BR-3
  
  DOI: 10.1016/j.chembiol.2019.05.010
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:CVCL_0033
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sciencedirect.com/science/article/pii/S2451945619301795
www.tandfonline.com www.tandfonline.com

Frequency determination of breast tumor-reactive CD4 and CD8 T cells in humans: unveiling the antitumor immune response

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1080/2162402X.2019.1607674
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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tandfonline.com/doi/abs/10.1080/2162402X.2019.1607674
www.tandfonline.com www.tandfonline.com

Frequency determination of breast tumor-reactive CD4 and CD8 T cells in humans: unveiling the antitumor immune response

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1080/2162402X.2019.1607674
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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tandfonline.com/doi/full/10.1080/2162402X.2019.1607674
onlinelibrary.wiley.com onlinelibrary.wiley.com

Low expression of CRISP3 predicts a favorable prognosis in patients with mammary carcinoma

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID: CVCL_0033
  
  DOI: 10.1002/jcp.28043
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
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  RRID:CVCL_0033 RRIDCUR:Unrecognized
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onlinelibrary.wiley.com/doi/full/10.1002/jcp.28043
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Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function

2
1. scibot 28 Jul 2021
  
  in Public
  
  CVCL_0033
  
  DOI: 10.1016/j.ccell.2017.09.002
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @Jmenke
  
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  RRID:CVCL_0033 RRIDCUR:Duplicate RRIDCUR:Validated
2. scibot 28 Jul 2021
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.ccell.2017.09.002
  
  Resource: (ATCC Cat# HTB-30, RRID:CVCL_0033)
  
  Curator: @Jmenke
  
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  RRID:CVCL_0033 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610817304063
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Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer

1
1. scibot 27 Jul 2021
  
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  HTB30
  
  DOI: 10.1016/j.ccell.2018.10.003
  
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sciencedirect.com/science/article/pii/S1535610818304690
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Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

1
1. scibot 03 Jul 2021
  
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  HTB-30
  
  DOI: 10.1016/j.molcel.2021.06.014
  
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cell.com/molecular-cell/fulltext/S1097-2765(21)00493-7
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Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target

1
1. scibot 01 Jul 2021
  
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  SKBR3
  
  DOI: 10.1016/j.biocel.2021.106028
  
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sciencedirect.com/science/article/pii/S1357272521001060
Jun 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 25 Jun 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.1111/bph.15509
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15509
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Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors

1
1. scibot 24 Jun 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.isci.2021.102619
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8193615/
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A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

1
1. scibot 16 Jun 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.3390/cancers13112840
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
May 2021
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Deciphering the signaling network of breast cancer improves drug sensitivity prediction

1
1. scibot 01 May 2021
  
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  HTB-30
  
  DOI: 10.1016/j.cels.2021.04.002
  
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sciencedirect.com/science/article/pii/S2405471221001113
Apr 2021
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
1. scibot 24 Apr 2021
  
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  HTB-30
  
  DOI: 10.1016/j.cell.2020.07.009
  
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sciencedirect.com/science/article/pii/S0092867420308746
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Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer

1
1. scibot 17 Apr 2021
  
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  HTB-30
  
  DOI: 10.1016/j.ccell.2020.05.010
  
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sciencedirect.com/science/article/pii/S1535610820302609
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A pan-cancer transcriptome analysis of exitron splicing identifies novel cancer driver genes and neoepitopes

1
1. scibot 16 Apr 2021
  
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  HTB-30
  
  DOI: 10.1016/j.molcel.2021.03.028
  
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sciencedirect.com/science/article/pii/S1097276521002239
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Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment

1
1. scibot 14 Apr 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.cmet.2021.03.023
  
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cell.com/cell-metabolism/fulltext/S1550-4131(21)00130-3
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Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis

1
1. scibot 11 Apr 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.molcel.2021.01.033
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8384339/
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Characterization of a novel mCH3 conjugated anti-PcrV scFv molecule

1
1. scibot 06 Apr 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.1038/s41598-021-86491-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8010009/
Mar 2021
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Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer

1
1. scibot 11 Mar 2021
  
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  HTB-30
  
  DOI: 10.1016/j.celrep.2021.108822
  
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sciencedirect.com/science/article/pii/S2211124721001364
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Intein-mediated cytoplasmic reconstitution of a split toxin enables selective cell ablation in mixed populations and tumor xenografts

1
1. scibot 02 Mar 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.1073/pnas.2006603117
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7486740/
Feb 2021
biosignaling.biomedcentral.com biosignaling.biomedcentral.com

L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness

1
1. scibot 25 Feb 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.1186/s12964-021-00710-5
  
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biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00710-5
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Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration

1
1. scibot 11 Feb 2021
  
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  SKRB-3 cells
  
  DOI: 10.1016/j.cub.2021.01.007
  
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sciencedirect.com/science/article/pii/S0960982221000403
Jan 2021
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A FOXO-dependent replication checkpoint restricts proliferation of damaged cells

1
1. scibot 27 Jan 2021
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.celrep.2020.108675
  
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sciencedirect.com/science/article/pii/S2211124720316648
Dec 2020
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Estrogen-induced hypomethylation and overexpression of YAP1 facilitate breast cancer cell growth and survival

1
1. scibot 07 Dec 2020
  
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  RRID: CVCL_0033
  
  DOI: 10.1016/j.neo.2020.11.002
  
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sciencedirect.com/science/article/pii/S1476558620301706
Nov 2020
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G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

1
1. scibot 12 Nov 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.celrep.2020.108341
  
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sciencedirect.com/science/article/pii/S2211124720313309
Oct 2020
www.cell.com www.cell.com

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

1
1. scibot 18 Oct 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.chembiol.2020.07.011
  
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cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
mcr.aacrjournals.org mcr.aacrjournals.org

Elevated V-ATPase activity following PTEN loss is required for enhanced oncogenic signaling in breast cancer

1
1. scibot 16 Oct 2020
  
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  RRID: CVCL_0033
  
  DOI: 10.1158/1541-7786.MCR-20-0088
  
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mcr.aacrjournals.org/content/18/10/1477
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity

1
1. scibot 30 Sep 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.ebiom.2020.102996
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7501074/
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Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growth in a Mouse Model of HER-2pos Disease

1
1. scibot 23 Sep 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.3390/vaccines8010072
  
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mdpi.com/2076-393X/8/1/72
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Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains

1
1. scibot 23 Sep 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.1038/s41598-020-69242-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7376038/
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Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

1
1. scibot 17 Sep 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.cell.2020.05.053
  
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sciencedirect.com/science/article/pii/S0092867420306863
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Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

1
1. scibot 12 Sep 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.7554/eLife.56913
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
mct.aacrjournals.org mct.aacrjournals.org

ARX788, a Site-specific anti-HER2 Antibody Drug Conjugate, Demonstrates Potent and Selective Activity in HER2 Low and T-DM1 Resistant Breast and Gastric Cancers

1
1. scibot 11 Sep 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.1158/1535-7163.MCT-19-1004
  
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mct.aacrjournals.org/content/19/9/1833
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Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

1
1. scibot 10 Sep 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.1016/j.cell.2020.02.019
  
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cell.com/cell/fulltext/S0092-8674(20)30163-X
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Breast Cancer Targeted/ Therapeutic with Double and Triple Fusion Immunotoxins

1
1. scibot 10 Sep 2020
  
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  DOI: 10.1016/j.jsbmb.2020.105651
  
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sciencedirect.com/science/article/pii/S0960076019303115
europepmc.org europepmc.org

Strategic Trastuzumab Mediated Crosslinking Driving Concomitant HER2 and HER3 Endocytosis and Degradation in Breast Cancer.

1
1. scibot 10 Sep 2020
  
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  RRID:CVCL_0033
  
  DOI: 10.7150/jca.32470
  
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europepmc.org/article/PMC/PMC7097966
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Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity

1
1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.02.015
  
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sciencedirect.com/science/article/pii/S0092867420301598
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FGF13 promotes metastasis of triple‐negative breast cancer

1
1. scibot 08 Sep 2020
  
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  DOI: 10.1002/ijc.32874
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32874
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Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment

1
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  RRID:CVCL_0033
  
  DOI: 10.1038/s41596-020-0355-z
  
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nature.com/articles/s41596-020-0355-z
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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

1
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  DOI: 10.1016/j.celrep.2020.107840
  
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sciencedirect.com/science/article/pii/S2211124720308214
onlinelibrary.wiley.com onlinelibrary.wiley.com

ZIC2 is downregulated and represses tumor growth via the regulation of STAT3 in breast cancer

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1002/ijc.32922
  
  Resource: (ICLC Cat# HTL03005, RRID:CVCL_0033)
  
  Curator: @Naa003
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32922
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Inhibition of Notch1 reverses EMT and chemoresistance to cisplatin via direct down‐regulation of MCAM in triple‐negative breast cancer cells

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID: CVCL_0033
  
  DOI: 10.1002/ijc.32911
  
  Resource: (ICLC Cat# HTL03005, RRID:CVCL_0033)
  
  Curator: @Naa003
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32911
Aug 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Selective and Effective Cancer Treatments using Target‐Switchable Intracellular Bacterial Toxin Delivery Systems

1
1. scibot 30 Aug 2020
  
  in Public
  
  SK‐BR‐3
  
  DOI: 10.1002/adtp.202000043
  
  Resource: (ICLC Cat# HTL03005, RRID:CVCL_0033)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0033
  
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onlinelibrary.wiley.com/doi/10.1002/adtp.202000043
onlinelibrary.wiley.com onlinelibrary.wiley.com

The GEF‐H1/PKD3 signaling pathway promotes the maintenance of triple negative breast cancer stem cells

1
1. scibot 17 Aug 2020
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1002/ijc.32798
  
  Resource: (ICLC Cat# HTL03005, RRID:CVCL_0033)
  
  Curator: @Naa003
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32798
Jan 2020
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Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

1
1. scibot 13 Jan 2020
  
  in Public
  
  CVCL_0033
  
  DOI: 10.1016/j.celrep.2019.08.105
  
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sciencedirect.com/science/article/pii/S2211124719311672
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Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.chembiol.2019.05.005
  
  Resource: (ICLC Cat# HTL03005, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2451945619301746
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Evaluation of Newcastle Disease Virus Mediated Dendritic Cell Activation and Cross‐priming Tumor‐specific Immune Responses Ex Vivo

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1002/ijc.32694
  
  Resource: (ICLC Cat# HTL03005, RRID:CVCL_0033)
  
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.32694
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The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1038/s41419-019-1950-1
  
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nature.com/articles/s41419-019-1950-1
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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0033
  
  DOI: 10.1016/j.cmet.2019.01.020
  
  Resource: (ICLC Cat# HTL03005, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S1550413119300208
Nov 2018
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Genome-Scale Signatures of Gene Interaction from Compound Screens Predict Clinical Efficacy of Targeted Cancer Therapies

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-30
  
  Curator: @Jmenke
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2405471218300097
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Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0033
  
  Curator: @Jmenke
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S0092867418311796
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Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis

1
1. scibot 05 Nov 2018
  
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  RRID:CVCL_0033
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2211124718308635
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Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB30
  
  Curator: @Jmenke
  
  Resource used:
  
  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S0092867418303088
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Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0033
  
  Curator: @evieth
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2405471218301923
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Cellosaurus, a Cell-Line Knowledge Resource

1
1. scibot 05 Nov 2018
  
  in Public
  
  CVCL_0033
  
  Curator: @evieth
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5945021/
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Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0033
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S1535610818301740
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CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-30
  
  Curator: @Jmenke
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S0092867418300448
onlinelibrary.wiley.com onlinelibrary.wiley.com

Phagocytosis of antibody‐opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0033
  
  Curator: @evieth
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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onlinelibrary.wiley.com/doi/full/10.1111/tra.12552
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Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID: CVCL_0033
  
  Curator: @evieth
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S2405471218300541
Nov 2017
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Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition

1
1. scibot 08 Nov 2017
  
  in Public
  
  HTB-30
  
  Curator: @Jmenke
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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sciencedirect.com/science/article/pii/S1097276517304914
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GLUL Promotes Cell Proliferation in Breast Cancer

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0033
  
  Curator: @gabimpine
  
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  (IZSLER Cat# BS TCL 156, RRID:CVCL_0033)
  
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onlinelibrary.wiley.com/doi/10.1002/jcb.25775/full

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