40 Matching Annotations
  1. Oct 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MIR17HG Expression Is Transcriptionally Regulated by PAX3::FOXO1 and MYCN and is Necessary for Oncogenic Activity in Fusion-Positive Rhabdomyosarcoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13641197/
  3. Jul 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers
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    sciencedirect.com/science/article/pii/S2666379126003393
  5. May 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAPRT expression and epigenetic regulation in pediatric rhabdomyosarcoma as a potential biomarker for NAMPT inhibition
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13184901/
  7. Apr 2026
  8. www.sciencedirect.com www.sciencedirect.com
    Acyltransferase ZDHHC22 promotes N-Myc transcriptional activation to drive neuroblastoma progression and chemoresistance
    1
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    sciencedirect.com/science/article/pii/S1097276526002364
  9. aacrjournals.org aacrjournals.org
    Endoglin-directed CAR-T cells Comprehensively Target Tumors in Advanced Sarcomas
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    aacrjournals.org/cancerimmunolres/article/13/10/1591/765477/Endoglin-Directed-CAR-T-Cells-Comprehensively
  10. aacrjournals.org aacrjournals.org
    Anti-tumor activity of trastuzumab deruxtecan in pediatric solid tumors with variable HER2 expression
    1
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    aacrjournals.org/mct/article/25/1/156/771291/Antitumor-Activity-of-Trastuzumab-Deruxtecan-in
  11. Feb 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Involvement of the FGF8/FGF receptor signaling pathway in the maintenance and progression of fusion-positive rhabdomyosarcoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12928154/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12925509/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic targeting of YOD1 disrupts the PAX-FOXO1-N-Myc feedback loop in rhabdomyosarcoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12892920/
  15. Nov 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12477665/
  17. Aug 2025
  18. www.science.org www.science.org
    Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer
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    science.org/doi/10.1126/sciadv.adt1798
  19. Jul 2025
  20. www.biorxiv.org www.biorxiv.org
    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
    1
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    biorxiv.org/content/10.1101/2025.07.21.665972v1
  21. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
    1
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    52.53.155.43/383127a3ba30f18153ba559aaeac9e14b54b55e6/1-s2.0-S2589004225014105-main-html.html
  22. www.sciencedirect.com www.sciencedirect.com
    Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo
    1
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    sciencedirect.com/science/article/pii/S2211124725006941
  23. Jun 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12170903/
  25. Apr 2025
  26. www.sciencedirect.com www.sciencedirect.com
    MiR-1 alleviates chronic heart failure through HCN2/HCN4 axis in vitro
    1
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    sciencedirect.com/science/article/pii/S0040816625002010
  27. Dec 2024
  28. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
    1
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
  29. www.nature.com www.nature.com
    GEFT inhibits the GSDM-mediated proptosis signalling pathway, promoting the progression and drug resistance of rhabdomyosarcoma
    1
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    nature.com/articles/s41419-024-07243-y
  30. Sep 2024
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Patient-derived rhabdomyosarcoma cells recapitulate the genetic and transcriptomic landscapes of primary tumors
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11417342/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SJPedPanel: A pan-cancer gene panel for childhood malignancies to enhance cancer monitoring and early detection
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393547/
  33. Aug 2024
  34. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
    1
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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  35. May 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of NAD+-dependent metabolic processes induces cellular necrosis and tumor regression in rhabdomyosarcoma models
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841338/
  37. Feb 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of BV6-Induced Sensitization to the NK Cell Killing of Pediatric Rhabdomyosarcoma Spheroids
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10047333/
  39. www.biorxiv.org www.biorxiv.org
    Somatic gene delivery for flexible in vivo modeling of high-risk sarcoma
    1
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    biorxiv.org/content/10.1101/2024.01.30.577924v1
  40. Oct 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducing Mitotic Catastrophe as a Therapeutic Approach to Improve Outcomes in Ewing Sarcoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10605681/
  42. 52.53.155.43 52.53.155.43
    Preprints202309.2164.v1-html.html
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    52.53.155.43/90a9b3d86bbedfe17ef71e7103069ab41e9b198e/Preprints202309.2164.v1-html.html
  43. Jun 2023
  44. aacrjournals.org aacrjournals.org
    Sequential targeting of retinoblastoma and DNA synthesis pathways is a therapeutic strategy for sarcomas that can be monitored in real-time
    1
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    aacrjournals.org/cancerres/article/83/6/939/718579/Sequential-Targeting-of-Retinoblastoma-and-DNA
  45. Oct 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors
    1
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    sciencedirect.com/science/article/pii/S2666634022004032
  47. Aug 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epitope Detection in Monocytes (EDIM) As a New Method of Liquid Biopsy in Pediatric Rhabdomyosarcoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9404738/
  49. Apr 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGF7–FGFR2 autocrine signaling increases growth and chemoresistance of fusion‐positive rhabdomyosarcomas
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8936514/
  51. Jan 2022
  52. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
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    sciencedirect.com/science/article/pii/S2211124721017423
  53. Nov 2021
  54. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
    1
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    mct.aacrjournals.org/content/20/11/2151
  55. Jul 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6277197/
  57. May 2021
  58. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Functional impact of a germline RET mutation in alveolar rhabdomyosarcoma
    1
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    pubmed.ncbi.nlm.nih.gov/33722797/
  59. Apr 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Lipid-derived electrophiles mediate the effects of chemotherapeutic topoisomerase I poisons
    1
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    sciencedirect.com/science/article/pii/S2451945620304748
  61. Feb 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rhabdomyosarcoma Cells Produce Their Own Extracellular Matrix With Minimal Involvement of Cancer-Associated Fibroblasts: A Preliminary Study
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7878542/
  63. Nov 2020
  64. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
    1
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    pubmed.ncbi.nlm.nih.gov/33147457/
  65. Sep 2020
  66. molecularcasestudies.cshlp.org molecularcasestudies.cshlp.org
    Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma
    1
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    molecularcasestudies.cshlp.org/content/6/3/a004853.full
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Next‐generation sequencing reveals a novel role of lysine‐specific demethylase 1 in adhesion of rhabdomyosarcoma cells
    1
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32806
  68. Nov 2018
  69. www.sciencedirect.com www.sciencedirect.com
    A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response
    1
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    sciencedirect.com/science/article/pii/S0092867418301090