36 Matching Annotations
  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    Endoglin-directed CAR-T cells Comprehensively Target Tumors in Advanced Sarcomas
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    aacrjournals.org/cancerimmunolres/article/13/10/1591/765477/Endoglin-Directed-CAR-T-Cells-Comprehensively
  3. Apr 2026
  4. aacrjournals.org aacrjournals.org
    Anti-tumor activity of trastuzumab deruxtecan in pediatric solid tumors with variable HER2 expression
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    aacrjournals.org/mct/article/25/1/156/771291/Antitumor-Activity-of-Trastuzumab-Deruxtecan-in
  5. Feb 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Involvement of the FGF8/FGF receptor signaling pathway in the maintenance and progression of fusion-positive rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12928154/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12925509/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic targeting of YOD1 disrupts the PAX-FOXO1-N-Myc feedback loop in rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12892920/
  9. Nov 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12477665/
  11. Aug 2025
  12. www.science.org www.science.org
    Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer
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    science.org/doi/10.1126/sciadv.adt1798
  13. Jul 2025
  14. www.biorxiv.org www.biorxiv.org
    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
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    biorxiv.org/content/10.1101/2025.07.21.665972v1
  15. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    52.53.155.43/383127a3ba30f18153ba559aaeac9e14b54b55e6/1-s2.0-S2589004225014105-main-html.html
  16. www.sciencedirect.com www.sciencedirect.com
    Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo
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    sciencedirect.com/science/article/pii/S2211124725006941
  17. Jun 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12170903/
  19. Apr 2025
  20. www.sciencedirect.com www.sciencedirect.com
    MiR-1 alleviates chronic heart failure through HCN2/HCN4 axis in vitro
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    sciencedirect.com/science/article/pii/S0040816625002010
  21. Dec 2024
  22. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
  23. www.nature.com www.nature.com
    GEFT inhibits the GSDM-mediated proptosis signalling pathway, promoting the progression and drug resistance of rhabdomyosarcoma
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    nature.com/articles/s41419-024-07243-y
  24. Sep 2024
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Patient-derived rhabdomyosarcoma cells recapitulate the genetic and transcriptomic landscapes of primary tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11417342/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SJPedPanel: A pan-cancer gene panel for childhood malignancies to enhance cancer monitoring and early detection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393547/
  27. Aug 2024
  28. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  29. May 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of NAD+-dependent metabolic processes induces cellular necrosis and tumor regression in rhabdomyosarcoma models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841338/
  31. Feb 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of BV6-Induced Sensitization to the NK Cell Killing of Pediatric Rhabdomyosarcoma Spheroids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10047333/
  33. www.biorxiv.org www.biorxiv.org
    Somatic gene delivery for flexible in vivo modeling of high-risk sarcoma
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    biorxiv.org/content/10.1101/2024.01.30.577924v1
  34. Oct 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducing Mitotic Catastrophe as a Therapeutic Approach to Improve Outcomes in Ewing Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10605681/
  36. 52.53.155.43 52.53.155.43
    Preprints202309.2164.v1-html.html
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    52.53.155.43/90a9b3d86bbedfe17ef71e7103069ab41e9b198e/Preprints202309.2164.v1-html.html
  37. Jun 2023
  38. aacrjournals.org aacrjournals.org
    Sequential targeting of retinoblastoma and DNA synthesis pathways is a therapeutic strategy for sarcomas that can be monitored in real-time
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    aacrjournals.org/cancerres/article/83/6/939/718579/Sequential-Targeting-of-Retinoblastoma-and-DNA
  39. Oct 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors
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    sciencedirect.com/science/article/pii/S2666634022004032
  41. Aug 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epitope Detection in Monocytes (EDIM) As a New Method of Liquid Biopsy in Pediatric Rhabdomyosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9404738/
  43. Apr 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGF7–FGFR2 autocrine signaling increases growth and chemoresistance of fusion‐positive rhabdomyosarcomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC8936514/
  45. Jan 2022
  46. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2211124721017423
  47. Nov 2021
  48. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
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    mct.aacrjournals.org/content/20/11/2151
  49. Jul 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6277197/
  51. May 2021
  52. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Functional impact of a germline RET mutation in alveolar rhabdomyosarcoma
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    pubmed.ncbi.nlm.nih.gov/33722797/
  53. Apr 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Lipid-derived electrophiles mediate the effects of chemotherapeutic topoisomerase I poisons
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    sciencedirect.com/science/article/pii/S2451945620304748
  55. Feb 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rhabdomyosarcoma Cells Produce Their Own Extracellular Matrix With Minimal Involvement of Cancer-Associated Fibroblasts: A Preliminary Study
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    ncbi.nlm.nih.gov/pmc/articles/PMC7878542/
  57. Nov 2020
  58. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
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    pubmed.ncbi.nlm.nih.gov/33147457/
  59. Sep 2020
  60. molecularcasestudies.cshlp.org molecularcasestudies.cshlp.org
    Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma
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    molecularcasestudies.cshlp.org/content/6/3/a004853.full
  61. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Next‐generation sequencing reveals a novel role of lysine‐specific demethylase 1 in adhesion of rhabdomyosarcoma cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32806
  62. Nov 2018
  63. www.sciencedirect.com www.sciencedirect.com
    A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response
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    sciencedirect.com/science/article/pii/S0092867418301090