291 Matching Annotations
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  2. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Multimodal cell death induced by indirubin-3′-oxime through inhibition of Akt/mTOR axis in lung cancer cells
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    sciencedirect.com:5037/science/article/pii/S0009279725004818
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    Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy
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    sciencedirect.com:5037/science/article/pii/S0006295225008275
  5. Nov 2025
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    2025.11.15.688645v1.full-html.html
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    PROTAC-mediated structure–function disruption of CD26: a therapeutic strategy for driver-negative non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2352396425004700
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70220
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    Down-regulation of MFNG promotes the metastatic potential of lung adenocarcinoma by regulating TGF-β/Smad signaling
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    Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy
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    The α5-nAChR/GINS4 axis contributed to nicotine-promoted lung adenocarcinoma progression
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  13. Oct 2025
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    Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer
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    Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties
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    Targeted citrullination enables p53 binding to non-canonical sites
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    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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  18. Sep 2025
  19. 54.241.53.176 54.241.53.176
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    RAD21-mediated epigenetic regulation promotes lung adenocarcinoma progression and sensitizes cancer cells to ERK-targeted therapy
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    Notch3 mediated TGF-β1 activation enhances epithelial-mesenchymal transition and cancer stemness in non-small lung cancer
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    Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response
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  24. Aug 2025
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    DACT3-DVL1 Interaction-Mediated Canonical WNT Signaling Regulates Non-Small Cell Lung Cancer Progression and Cisplatin Resistance
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    53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway
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  31. Jul 2025
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    LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling
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    High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma
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    Δ133p53α and Δ160p53α isoforms of the tumor suppressor protein p53 exert dominant-negative effect primarily by co-aggregation
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    elifesciences.org/articles/106469
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    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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  40. Jun 2025
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    Harmine inhibits non-small cell lung cancer growth by targeting PDE4D and inducing ferroptosis
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    The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein
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  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy
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    PIN1 serves as a prognostic and therapeutic biomarker in lung adenocarcinoma
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  46. May 2025
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    NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors
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    MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer
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    FAT1 Enhances the Sensitivity of Non-Small Cell Lung Cancer to VCP Inhibitors by Regulating the Activation of the Endoplasmic Reticulum Stress Pathway
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    Tumor cell-intrinsic circular RNA circFNDC3B attenuates CD8+ T cells infiltration in non-small cell lung cancer
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  52. Apr 2025
  53. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Aberrant expression of nuclear prothymosin α contributes to epithelial-mesenchymal transition in lung cancer
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    EFTUD2 is a promising diagnostic and prognostic indicator involved in the tumor immune microenvironment and glycolysis of lung adenocarcinoma
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    Combined inhibition of hexokinase 2 and pyruvate dehydrogenase surmounts SHP2 inhibitor resistance in non-small cell lung cancer with hybrid metabolic state harboring KRAS Q61H mutation
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    Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies
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    Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage
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  59. Mar 2025
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    A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer
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    Lactylation orchestrates ubiquitin-independent degradation of cGAS and promotes tumor growth
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    SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
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    Discovery and characterization of a novel telomerase alternative splicing isoform that protects lung cancer cells from chemotherapy induced cell death
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  64. Feb 2025
  65. translational-medicine.biomedcentral.com translational-medicine.biomedcentral.com
    JMJD6 K375 acetylation restrains lung cancer progression by enhancing METTL14/m6A/SLC3A2 axis mediated cell ferroptosis
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    Targeting Tumor-Associated Sialic Acids using Chimeric Switch Receptors based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
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    Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolism
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    Phosphorylation of SIRT7 by ATM causes DNA mismatch repair downregulation and adaptive mutability during chemotherapy
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    Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability
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  70. Jan 2025
  71. www.nature.com www.nature.com
    Photothermal nanofiber-mediated photoporation for gentle and efficient intracellular delivery of macromolecules
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    Mina53 catalyzes arginine demethylation of p53 to promote tumor growth
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    Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation
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  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers
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    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2
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  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Demethylzeylasteral inhibits oxidative phosphorylation complex biogenesis by targeting LRPPRC in lung cancer
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  78. Dec 2024
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography
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    Pan-cancer analysis of biallelic inactivation in tumor suppressor genes identifies KEAP1 zygosity as a predictive biomarker in lung cancer
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    The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity
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    p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis
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    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    Lovastatin-mediated pharmacological inhibition of Formin protein DIAPH1 suppresses tumor immune escape and boosts immunotherapy response
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  86. Nov 2024
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chelating drug-induced labile Zn2+ with nanoparticle-encapsulated TPEN at low dose enhances lung cancer chemotherapy through inhibiting ABCB1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539588/
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  89. Oct 2024
  90. www.sciencedirect.com www.sciencedirect.com
    Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
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  91. link.springer.com link.springer.com
    Inhibition of EREG/ErbB/ERK by Astragaloside IV reversed taxol-resistance of non-small cell lung cancer through attenuation of stemness via TGFβ and Hedgehog signal pathway
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
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  93. Sep 2024
  94. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
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    CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway
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  96. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer
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  98. Aug 2024
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    Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations
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    Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
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  208. Mar 2022
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    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
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    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
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  213. Feb 2022
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    Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity
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    Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules
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    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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    Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer
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  221. Dec 2021
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    Protein modifications throughout the lung cancer proteome unravel the cancer-specific regulation of glycolysis
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    Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways
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  224. Nov 2021
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    SAGE1: a Potential Target Antigen for Lung Cancer T-Cell Immunotherapy
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    HNRNPA2B1 as a trigger of RNA switch modulates the miRNA-mediated regulation of CDK6
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    FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
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  228. Oct 2021
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    RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage
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    EGFR transcriptionally upregulates UTX via STAT3 in non-small cell lung cancer
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    Quantitative differences between cyclin-dependent kinases underlie the unique functions of CDK1 in human cells
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  232. Sep 2021
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    Multiplatform discovery and regulatory function analysis of structural variations in non-small cell lung carcinoma
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  235. Aug 2021
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