72 Matching Annotations
  1. Jul 2026
  2. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70648
  3. www.nature.com www.nature.com
    FATP2-mediated lipid metabolism enhances chimeric antigen receptor T-cell therapy resistance in B-cell acute lymphoblastic leukemia
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    nature.com/articles/s41375-026-03030-0
  4. Jun 2026
  5. www.biorxiv.org www.biorxiv.org
    Dynamic UFMylation governs cellular fitness by coordinating multi-organelle proteostasis
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    biorxiv.org/content/10.64898/2026.03.27.714830v1
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of CAR T cells Targeting a Surface RNA Binding Protein for the Treatment of Acute Leukemias
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    pmc.ncbi.nlm.nih.gov/articles/PMC13271017/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Low-Strength Type I Interferon Signaling Promotes CAR T Cell Treatment Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13249101/
  8. May 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activity of direct KRAS(G12C) inhibitors in preclinical models of pediatric cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12776615/
  10. aacrjournals.org aacrjournals.org
    Constitutive STAT3 signaling, in comparison to STAT5, enhances CAR T cell efficacy and lowers systemic toxicity
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    aacrjournals.org/cancerimmunolres/article/14/5/845/784457/Constitutive-STAT3-Signaling-in-Comparison-with
  11. Apr 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering functionality-optimized fully human B7-H3 CAR T cells for enhanced solid tumor therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13198247/
  13. www.science.org www.science.org
    T cell polarization and NFAT activation are stiffness dependent and differentially regulated by the channels PIEZO1 and ORAI1
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    science.org/doi/10.1126/scisignal.adt9566
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055633/
  15. Mar 2026
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring the Role of Environmental Factors on Chromosomal Translocations Associated With Childhood Leukaemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12967601/
  17. www.sciencedirect.com www.sciencedirect.com
    β-hydroxybutyrate enhances the metabolic fitness of CAR T cells in cancer
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    sciencedirect.com/science/article/pii/S0092867426001698
  18. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Disruption of Cytoskeleton Induces Physiologically and Morphologically Dysfunctional Mitochondria in B-ALL Cells
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/cbf.70190
  19. Feb 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PD-1 suppresses CAR signaling by forming the inhibitory signalosome colocalizing to CAR microclusters
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    pmc.ncbi.nlm.nih.gov/articles/PMC12855910/
  21. Dec 2025
  22. 54.241.53.176 54.241.53.176
    2025.12.16.694090v1.full-html.html
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    54.241.53.176/812ec14855db9ada0d4741c17647b049c71ee6c0/2025.12.16.694090v1.full-html.html
  23. Nov 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591092/
  25. Oct 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    General anaesthetics reduce acute lymphoblastic leukaemia malignancies in vitro and in vivo via CXCR4 and osteopontin mediated mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11128051/
  27. Sep 2025
  28. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Enhancing Anti-Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515472
  29. Jul 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  31. Jun 2025
  32. www.sciencedirect.com www.sciencedirect.com
    iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumors
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    sciencedirect.com/science/article/pii/S266637912500268X
  33. www.sciencedirect.com www.sciencedirect.com
    Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling
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    sciencedirect.com/science/article/pii/S153561082500220X
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant
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    pmc.ncbi.nlm.nih.gov/articles/PMC11184310/
  35. May 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Highly specific Immunoproteasome inhibitor M3258 induces proteotoxic stress and apoptosis in KMT2A::AFF1 driven acute lymphoblastic leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089620/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinguishing acute leukemia subtypes: The role of hsa_circ_0012152 and hsa_circ_0020093 in peripheral blood
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    pmc.ncbi.nlm.nih.gov/articles/PMC12082030/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12077275/
  39. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225008090-main-html.html
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  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GREM1 deficiency induced bone marrow adipose niche promotes B-cell acute lymphoblastic leukemia disease progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141984/
  41. Apr 2025
  42. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/73f4a278983fd3a9b93fed6443158024ffc69ddc/PDF-html.html
  43. Feb 2025
  44. www.sciencedirect.com www.sciencedirect.com
    The IAP antagonist tolinapant enhances the anti-tumor activity of cell therapies
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    sciencedirect.com/science/article/pii/S0014299925001542
  45. www.sciencedirect.com www.sciencedirect.com
    Enhanced conversion of T cells into CAR T cells by modulation of the MAPK/ERK pathway
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    sciencedirect.com/science/article/pii/S2666379125000436
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel B7-H3 CAR T cells show potent antitumor effects in glioblastoma: a preclinical study
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    pmc.ncbi.nlm.nih.gov/articles/PMC11784176/
  47. Jan 2025
  48. www.sciencedirect.com www.sciencedirect.com
    Bortezomib enhances the efficacy of BCMA CAR-T therapy through up-regulating BCMA expression in myeloma cells
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    sciencedirect.com/science/article/pii/S156757692500102X
  49. Dec 2024
  50. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
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    sciencedirect.com/science/article/pii/S0092867424013242
  51. www.sciencedirect.com www.sciencedirect.com
    EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
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    sciencedirect.com/science/article/pii/S1535610824004410
  52. Nov 2024
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  54. Sep 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel immunotherapeutics against LGR5 to target multiple cancer types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
  56. www.sciencedirect.com www.sciencedirect.com
    Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
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    sciencedirect.com/science/article/pii/S0092867424009565
  57. www.sciencedirect.com www.sciencedirect.com
    Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase
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    sciencedirect.com/science/article/pii/S0304383524006372
  58. Jul 2024
  59. www.sciencedirect.com www.sciencedirect.com
    Pre-B cell receptor acts as a selectivity switch for galectin-1 at the pre-B cell surface
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    sciencedirect.com/science/article/pii/S2211124724008702
  60. www.nature.com www.nature.com
    Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
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    nature.com/articles/s41375-024-02328-1
  61. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  62. www.cell.com www.cell.com
    Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00219-4
  63. Jun 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    General anaesthetics reduce acute lymphoblastic leukaemia malignancies in vitro and in vivo via CXCR4 and osteopontin mediated mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC11128051/
  65. May 2024
  66. pubs.acs.org pubs.acs.org
    Anticancer Study on IrIII and RhIII Half-Sandwich Complexes with the Bipyridylsulfonamide Ligand
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    pubs.acs.org/doi/10.1021/acs.inorgchem.3c03801
  67. www.biorxiv.org www.biorxiv.org
    Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations
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    biorxiv.org/content/10.1101/2024.01.26.576051v1
  68. Mar 2024
  69. www.nature.com www.nature.com
    BEHAV3D: a 3D live imaging platform for comprehensive analysis of engineered T cell behavior and tumor response
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    nature.com/articles/s41596-024-00972-6
  70. Jan 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAR Gene Delivery by T‐cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC10724389/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10774422/
  73. Nov 2023
  74. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells
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    sciencedirect.com/science/article/pii/S2589004223023647
  75. www.sciencedirect.com www.sciencedirect.com
    Epigenomic mapping reveals distinct B cell acute lymphoblastic leukemia chromatin architectures and regulators
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    sciencedirect.com/science/article/pii/S2666979X2300277X
  76. Sep 2023
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10472109/
  78. Aug 2023
  79. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B1
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13486
  80. 52.53.155.43 52.53.155.43
    Arsenic affects homologous recombination and single-strand annealing but not end-joining pathways during DNA double-strand break repair
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    52.53.155.43/383dbc1d7d8d7eb1a3a3549f976318eb9444e50e/The FEBS Journal - 2023 - Kurosawa-html.html
  81. Jul 2023
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Siglec-15 promotes evasion of adaptive immunity in B-cell acute lymphoblastic leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10351425/
  83. 52.53.155.43 52.53.155.43
    crc-23-0056-html.html
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  84. Apr 2023
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Niche-expressed Galectin-1 is involved in pre-B acute lymphoblastic leukemia relapse through pre-BCR activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10060685/
  86. Mar 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockdown of MEF2D inhibits the development and progression of B-cell acute lymphoblastic leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10007885/
  88. Dec 2022
  89. f1000research.com f1000research.com
    F1000Research Article: General anaesthetics reduce acute lymphoblastic leukaemia cell migration and homing <i>in vitro</i> and<i> in vivo</i> <i>via</i> CXCR4 and osteopontin mediated mechanisms.
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    f1000research.com/articles/11-1491
  90. Aug 2022
  91. www.sciencedirect.com www.sciencedirect.com
    hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia
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    sciencedirect.com/science/article/pii/S2666379122002609
  92. Jul 2022
  93. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13264
  94. Aug 2021
  95. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia
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    sciencedirect.com/science/article/pii/S1535610818305233
  96. www.sciencedirect.com www.sciencedirect.com
    BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
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    sciencedirect.com/science/article/pii/S2211124718316838
  97. www.sciencedirect.com www.sciencedirect.com
    TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate
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    sciencedirect.com/science/article/pii/S1934590921002885
  98. Apr 2021
  99. www.sciencedirect.com www.sciencedirect.com
    An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity
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    sciencedirect.com/science/article/pii/S245194562030475X
  100. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
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    sciencedirect.com/science/article/pii/S0092867420310138
  101. Sep 2020
  102. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Biomarker Profile for Prediction of Response to SMAC Mimetic Monotherapy in Pediatric Precursor B‐Cell Acute Lymphoblastic Leukemia
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32799
  103. Jan 2020
  104. www.sciencedirect.com www.sciencedirect.com
    Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610819302946
  105. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CD4 T cells target colorectal cancer antigens upregulated by oxaliplatin
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32620
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Human RECQL4 represses the RAD52‐mediated single‐strand annealing pathway after ionizing radiation or cisplatin treatment
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32670
  107. www.sciencedirect.com www.sciencedirect.com
    Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing
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    sciencedirect.com/science/article/pii/S1097276519300097