Hypothesis

40 Matching Annotations

Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Development of CAR T cells Targeting a Surface RNA Binding Protein for the Treatment of Acute Leukemias

1
1. scibot 18 Jun 2026
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1158/2159-8290.CD-25-0920
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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pmc.ncbi.nlm.nih.gov/articles/PMC13271017/
Mar 2026
www.sciencedirect.com www.sciencedirect.com

NOT-gated chimeric antigen receptor circuits in T and NK cells

1
1. scibot 31 Mar 2026
  
  in Public
  
  ATCCCRL1873
  
  DOI: 10.1016/j.cels.2026.101561
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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sciencedirect.com/science/article/pii/S2405471226000438
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia

1
1. scibot 06 Mar 2026
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1038/s44318-026-00707-1
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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pmc.ncbi.nlm.nih.gov/articles/PMC12953771/
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

BCR::ABL1-Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B-ALL Cells to Enhancer-Targeting Drugs

1
1. scibot 05 Mar 2026
  
  in Public
  
  CVCL_0093
  
  DOI: 10.1002/advs.202517231
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202517231
Oct 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

1
1. scibot 28 Oct 2025
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1002/advs.202511573
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511573
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens

1
1. scibot 27 Sep 2025
  
  in Public
  
  ATCCCRL-1873
  
  DOI: 10.1016/j.cell.2025.09.001
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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sciencedirect.com/science/article/pii/S0092867425010323
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Highly specific Immunoproteasome inhibitor M3258 induces proteotoxic stress and apoptosis in KMT2A::AFF1 driven acute lymphoblastic leukemia

1
1. scibot 22 May 2025
  
  in Public
  
  RRID: CVCL_0093
  
  DOI: 10.1038/s41598-025-01657-0
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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pmc.ncbi.nlm.nih.gov/articles/PMC12089620/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

1
1. scibot 21 May 2025
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1002/1878-0261.13792
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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pmc.ncbi.nlm.nih.gov/articles/PMC12077275/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

GREM1 deficiency induced bone marrow adipose niche promotes B-cell acute lymphoblastic leukemia disease progression

1
1. scibot 16 May 2025
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1002/ijc.35418
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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pmc.ncbi.nlm.nih.gov/articles/PMC12141984/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway–Deficient Acute Myeloid Leukemia

1
1. scibot 24 Apr 2025
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1158/2767-9764.CRC-24-0260
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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pmc.ncbi.nlm.nih.gov/articles/PMC12011380/
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 23 Mar 2025
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1158/2767-9764.crc-24-0260
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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52.53.155.43/bd8b1eb80c0a90d93d052e69613b249b6f3108d9/PDF-html.html
Jan 2025
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 24 Jan 2025
  
  in Public
  
  RRID: CVCL_0093
  
  DOI: 10.1111/febs.17374
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @inessasarian
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.17374
Dec 2024
www.sciencedirect.com www.sciencedirect.com

YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies

1
1. scibot 18 Dec 2024
  
  in Public
  
  CVCL_0093
  
  DOI: 10.1016/j.cell.2024.11.007
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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sciencedirect.com/science/article/pii/S0092867424013242
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress

1
1. scibot 07 Nov 2024
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1158/1535-7163.MCT-23-0487
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Novel immunotherapeutics against LGR5 to target multiple cancer types

1
1. scibot 25 Sep 2024
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1038/s44321-024-00121-2
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
www.sciencedirect.com www.sciencedirect.com

Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase

1
1. scibot 17 Sep 2024
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1016/j.canlet.2024.217242
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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sciencedirect.com/science/article/pii/S0304383524006372
Jun 2024
link.springer.com link.springer.com

Comparable efficacy of oral bendamustine versus intravenous administration in treating hematologic malignancies

1
1. scibot 28 Jun 2024
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1007/s00280-024-04688-y
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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link.springer.com/article/10.1007/s00280-024-04688-y
Mar 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 27 Mar 2024
  
  in Public
  
  CVCL_0093
  
  DOI: 10.1002/1878-0261.13638
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13638
Jan 2024
www.sciencedirect.com www.sciencedirect.com

DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

2
1. scibot 23 Jan 2024
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1016/j.cell.2023.12.032
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
  What is this?
  
  RRID:CVCL_0093
2. scibot 23 Jan 2024
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1016/j.cell.2023.12.032
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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RRID:CVCL_0093

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sciencedirect.com/science/article/pii/S0092867423014381
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Epigenomic mapping reveals distinct B cell acute lymphoblastic leukemia chromatin architectures and regulators

1
1. scibot 22 Nov 2023
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1016/j.xgen.2023.100442
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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URL

sciencedirect.com/science/article/pii/S2666979X2300277X
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Siglec-15 promotes evasion of adaptive immunity in B-cell acute lymphoblastic leukemia

1
1. scibot 19 Jul 2023
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1158/2767-9764.CRC-23-0056
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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ncbi.nlm.nih.gov/pmc/articles/PMC10351425/
52.53.155.43 52.53.155.43

crc-23-0056-html.html

1
1. scibot 13 Jul 2023
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1158/2767-9764.crc-23-0056
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @olekpark
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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52.53.155.43/a97c8d0b2c4db9c1d802055a62ec35907b04f0ad/crc-23-0056-html.html
Jun 2023
www.biorxiv.org www.biorxiv.org

DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

1
1. scibot 08 Jun 2023
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1101/2023.05.29.541540
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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biorxiv.org/content/10.1101/2023.05.29.541540v1
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Asparagine starvation suppresses histone demethylation through iron depletion

1
1. scibot 09 Apr 2023
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1016/j.isci.2023.106425
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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ncbi.nlm.nih.gov/pmc/articles/PMC10074807/
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Knockdown of MEF2D inhibits the development and progression of B-cell acute lymphoblastic leukemia

1
1. scibot 16 Mar 2023
  
  in Public
  
  RRID: CVCL_0093
  
  DOI: 10.21037/tcr-22-1778
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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ncbi.nlm.nih.gov/pmc/articles/PMC10007885/
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target

1
1. scibot 09 Feb 2023
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1158/2643-3230.BCD-20-0216
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC9783958/
Jun 2022
www.frontiersin.org www.frontiersin.org

Low Prevalence of ETV6::RUNX1 Fusion Gene in a Hispanic Population

1
1. scibot 09 Jun 2022
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.3389/fped.2022.837656
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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frontiersin.org/article/10.3389/fped.2022.837656/full
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells

1
1. scibot 27 Apr 2022
  
  in Public
  
  CVCL_0093
  
  DOI: 10.1016/j.celrep.2022.110752
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
Feb 2022
www.nature.com www.nature.com

Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture

1
1. scibot 12 Feb 2022
  
  in Public
  
  RRID: CVCL_0093
  
  DOI: 10.1038/s41596-021-00651-w
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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nature.com/articles/s41596-021-00651-w
Dec 2021
ashpublications.org ashpublications.org

ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during Asparaginase treatment

1
1. scibot 22 Dec 2021
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1182/bloodadvances.2020004041
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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ashpublications.org/bloodadvances/article/5/23/5164/477187/ALL-blasts-drive-primary-mesenchymal-stromal-cells
Sep 2021
www.sciencedirect.com www.sciencedirect.com

A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells

1
1. scibot 01 Sep 2021
  
  in Public
  
  CVCL_0093
  
  DOI: 10.1016/j.chembiol.2021.08.004
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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sciencedirect.com/science/article/pii/S2451945621003937
Aug 2021
elifesciences.org elifesciences.org

HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways

1
1. scibot 15 Aug 2021
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.7554/eLife.64148
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093
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elifesciences.org/articles/64148
Jul 2021
www.sciencedirect.com www.sciencedirect.com

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

1
1. scibot 31 Jul 2021
  
  in Public
  
  Human: RS4;11
  
  DOI: 10.1016/j.ccell.2019.11.001
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093 RRIDCUR:Missing
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RRIDCUR:Missing

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scibot

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sciencedirect.com/science/article/pii/S1535610819305215
www.sciencedirect.com www.sciencedirect.com

Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

1
1. scibot 31 Jul 2021
  
  in Public
  
  RS4;11
  
  DOI: 10.1016/j.celrep.2019.10.083
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0093
  
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  RRID:CVCL_0093 RRIDCUR:Missing
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RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719314056
www.sciencedirect.com www.sciencedirect.com

ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia

1
1. scibot 27 Jul 2021
  
  in Public
  
  CRL-1873
  
  DOI: 10.1016/j.ccell.2018.02.002
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:CVCL_0093
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_0093
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RRID:CVCL_0093

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818300230
May 2021
www.sciencedirect.com www.sciencedirect.com

Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation

1
1. scibot 12 May 2021
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1016/j.celrep.2021.109101
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0093
  
  What is this?
  
  RRID:CVCL_0093
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RRID:CVCL_0093

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721004356
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

1
1. scibot 20 Apr 2021
  
  in Public
  
  ACC 508
  
  DOI: 10.1016/j.molcel.2021.03.043
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0093
  
  What is this?
  
  RRID:CVCL_0093 RRIDCUR:Missing
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RRID:CVCL_0093

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521002641
Sep 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Biomarker Profile for Prediction of Response to SMAC Mimetic Monotherapy in Pediatric Precursor B‐Cell Acute Lymphoblastic Leukemia

1
1. scibot 08 Sep 2020
  
  in Public
  
  RRID:CVCL_0093
  
  DOI: 10.1002/ijc.32799
  
  Resource: (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0093
  
  What is this?
  
  RRID:CVCL_0093 RRIDCUR:Validated
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RRID:CVCL_0093

RRIDCUR:Validated

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.32799
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  RS4;11
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (ATCC Cat# CRL-1873, RRID:CVCL_0093)
  
  SciCrunch record: RRID:CVCL_0093
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0093 RRIDCUR:Missing
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RRID:CVCL_0093

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867416316853