243 Matching Annotations
  1. Oct 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Afro-Caribbean Prostate Cancer Model Reveals Ancestry-Specific Drug Vulnerabilities with Therapeutic Implications for Black Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12490968/
  3. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202511349
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated Omics and Multi-Cohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485374/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Detection of Genome‐Wide IGF‐1R Recruitment to Enhancer and Promoter Regions of Chromatin in Clinical Prostate Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12483945/
  6. Sep 2025
  7. www.biorxiv.org www.biorxiv.org
    Colorectal cancer-associated PCBP1 mutations disrupt protein stability in a dominant negative manner
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    biorxiv.org/content/10.1101/2025.09.23.678070v1
  8. www.nature.com www.nature.com
    Induction of ferroptosis in prostate cancer by CCDC719-13 via TRIM21-mediated ubiquitination of SLC7A11
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    nature.com/articles/s41418-025-01580-x
  9. www.nature.com www.nature.com
    KBTBD11 loss promotes AKT hyperactivation and therapeutic vulnerability in prostate cancer
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    nature.com/articles/s41388-025-03576-w
  10. www.sciencedirect.com www.sciencedirect.com
    A smart gene circuit for precise regulation of tumor cell behavior
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    sciencedirect.com/science/article/pii/S2405805X25001577
  11. journals.plos.org journals.plos.org
    A novel sialylation pathway mediated by extracellular vesicles in aggressive prostate cancer
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    journals.plos.org/plosone/article
  12. 52.53.155.43 52.53.155.43
    1-s2.0-S258900422501781X-main-html.html
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    52.53.155.43/f995d4046e40952b58ad424165ec4ce7948925e5/1-s2.0-S258900422501781X-main-html.html
  13. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1002/prp2.70173
  14. www.sciencedirect.com www.sciencedirect.com
    Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S221112472501006X
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drug-Repurposing Screen Identifies Thiostrepton as a Novel Regulator of the Tumor Suppressor DAB2IP
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    pmc.ncbi.nlm.nih.gov/articles/PMC12384208/
  16. Aug 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer activity of triterpene glycosides from the sea star Solaster pacificus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322260/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
  20. Jul 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stathmin Serine 16 Phosphorylation Is a Key Regulator of Cell Cycle Progression Without Activating Migration and Invasion In Vitro
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    pmc.ncbi.nlm.nih.gov/articles/PMC12293763/
  22. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
  23. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    52.53.155.43/383127a3ba30f18153ba559aaeac9e14b54b55e6/1-s2.0-S2589004225014105-main-html.html
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260511/
  25. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70083
  26. Jun 2025
  27. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer
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    sciencedirect.com/science/article/pii/S1097276525005040
  28. 52.53.155.43 52.53.155.43
    CTHRC1 promotes bone metastasis in prostate cancer
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    52.53.155.43/f04071ff6077a40bb108a3f03adfcb4d864028a7/Intl Journal of Cancer - 2025 - Sawada - CTHRC1 promotes bone metastasis in prostate cancer-html.html
  29. www.sciencedirect.com www.sciencedirect.com
    An integrated proteomic portrait of prostate cancer progression
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    sciencedirect.com/science/article/pii/S2211124725005996
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Downregulation of NONO Suppresses Proliferation, Migration, and Invasion in Metastatic Prostate Cancer
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    onlinelibrary.wiley.com/doi/10.1002/pros.24925
  31. www.cell.com www.cell.com
    BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways
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    cell.com/cell-reports/fulltext/S2211-1247(25)00550-9
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bromodomain and Extra-Terminal Family Proteins BRD2, BRD3, and BRD4 Contribute to H19-Dependent Transcriptional Regulation of Cell Adhesion Molecules, Modulating Metastatic Dissemination Program in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12101203/
  33. link.springer.com link.springer.com
    Targeted destruction of follicle stimulating hormone receptor-positive cancer cells in vitro and in vivo by a lytic peptide Phor21-FSHβ conjugate
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    link.springer.com/article/10.1186/s10020-025-01292-5
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC12129099/
  35. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70073
  36. www.mdpi.com www.mdpi.com
    A Novel Primary Cell Line Model of Localized Prostate Cancer and Radioresistance—A Role for Nicotinamide N-Methyltransferase
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    mdpi.com/2073-4409/14/11/819
  37. May 2025
  38. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70065
  39. link.springer.com link.springer.com
    GPR55 senses lactate to sustain motility in prostate cancer cells
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    link.springer.com/article/10.1007/s11010-025-05312-0
  40. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/19c04f2de7ab84853c8f1452d89a77f5ea183641/PDF-html.html
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Emerin Dysregulation Drives the Very-Small-Nuclear Phenotype and Lineage Plasticity That Associate with a Clinically Aggressive Subtype of Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079098/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secreted spermidine synthase reveals a paracrine role for PGC1α-induced growth suppression in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12019391/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system
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    pmc.ncbi.nlm.nih.gov/articles/PMC12077273/
  45. Apr 2025
  46. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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    52.53.155.43/fbc444166f400a01dc32894063d12537e1e236f5/rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antimicrobial, Quorum Sensing Inhibition, and Anti-Cancer Activities of Silver Nanoparticles Synthesized from Kenyan Bacterial Endophytes of Teclea nobilis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11989699/
  48. www.nature.com www.nature.com
    CD117/c-kit defines a prostate CSC-like subpopulation driving progression and TKI resistance
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    nature.com/articles/s41598-021-81126-6
  49. 52.53.155.43 52.53.155.43
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    52.53.155.43/009f5d6e39c430064ce0b832cf798a7e9caafb80/PDF-html.html
  50. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Adenosine A3 receptor antagonists as anti-tumor treatment in human prostate cancer: an in vitro study
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.70024
  51. www.sciencedirect.com www.sciencedirect.com
    Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer
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    sciencedirect.com/science/article/pii/S0925443925000675
  52. Mar 2025
  53. www.sciencedirect.com www.sciencedirect.com
    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
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    sciencedirect.com/science/article/pii/S2211124725002414
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11906863/
  55. Feb 2025
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process
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    pmc.ncbi.nlm.nih.gov/articles/PMC11820107/
  57. Jan 2025
  58. www.nature.com www.nature.com
    Bio-orthogonal tuning of matrix properties during 3D cell culture to induce morphological and phenotypic changes
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    nature.com/articles/s41596-024-01066-z
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774231/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In and out of Replication Stress: PCNA/RPA1-Based Dynamics of Fork Stalling and Restart in the Same Cell
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    pmc.ncbi.nlm.nih.gov/articles/PMC11765805/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11733533/
  62. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Clinical significance of stratifying prostate cancer patients through specific circulating genes
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13805
  63. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial uncouplers inhibit oncogenic E2F1 activity and prostate cancer growth
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    sciencedirect.com/science/article/pii/S266637912400661X
  64. www.sciencedirect.com www.sciencedirect.com
    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    sciencedirect.com/science/article/pii/S1074761324005685
  65. Dec 2024
  66. www.cell.com www.cell.com
    MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity
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    cell.com/cell-reports/abstract/S2211-1247(24)01471-2
  67. Nov 2024
  68. www.sciencedirect.com www.sciencedirect.com
    Spatial transcriptomics identifies RBM39 as a gene associated with Gleason score progression in prostate cancer
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    sciencedirect.com/science/article/pii/S2589004224025768
  69. Oct 2024
  70. www.sciencedirect.com www.sciencedirect.com
    Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
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    sciencedirect.com/science/article/pii/S2666379124004828
  71. Sep 2024
  72. www.sciencedirect.com www.sciencedirect.com
    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610824003179
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Proteogenomics of Prostate Cancer Radioresistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11411600/
  74. aacrjournals.org aacrjournals.org
    Squalene epoxidase metabolic dependency is a targetable vulnerability in castration-resistant prostate cancer
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    aacrjournals.org/cancerres/article/82/17/3032/708286/Squalene-Epoxidase-Metabolic-Dependency-Is-a
  75. www.sciencedirect.com www.sciencedirect.com
    PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
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    sciencedirect.com/science/article/pii/S1476558624000897
  76. Aug 2024
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10641717/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11315984/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  81. www.sciencedirect.com www.sciencedirect.com
    Protocol for establishing spontaneous metastasis in mice using a subcutaneous tumor model
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    sciencedirect.com/science/article/pii/S2666166724004040
  82. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Assessments of prostate cancer cell functions highlight differences between a pan-PI3K/mTOR inhibitor, gedatolisib, and single-node inhibitors of the PI3K/AKT/mTOR pathway
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13703
  83. www.cell.com www.cell.com
    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
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    cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    N‐glycosylation of the human neuropeptide QRFP receptor QRFPR is essential for ligand binding and receptor activation
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15337
  85. Jul 2024
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating miR-6880-5p in extracellular vesicle from plasma as a prognostic biomarker in endocrine therapy-treated castration-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285227/
  87. www.sciencedirect.com www.sciencedirect.com
    DNA damage-mediated FTO downregulation promotes CRPC progression by inhibiting FOXO3a via an m6A-dependent mechanism
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    sciencedirect.com/science/article/pii/S2589004224017309
  88. www.sciencedirect.com www.sciencedirect.com
    NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
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    sciencedirect.com/science/article/pii/S2451945624002083
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive investigation in oncogenic functions and immunological roles of NCBP2 and its validation in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11283080/
  90. www.embopress.org www.embopress.org
    Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer
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    embopress.org/doi/10.1038/s44319-024-00180-z
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11261775/
  92. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A vitamin D-based strategy overcomes chemoresistance in prostate cancer
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16492
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11238136/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identify Regulatory eQTLs by Multiome Sequencing in Prostate Single Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213234/
  95. Jun 2024
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC11210931/
  97. www.mdpi.com www.mdpi.com
    Genomic Characterization of Preclinical Prostate Cancer Cell Line Models
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    mdpi.com/1422-0067/25/11/6111
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sialic acid blockade inhibits the metastatic spread of prostate cancer to bone
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    ncbi.nlm.nih.gov/pmc/articles/PMC11134892/
  99. May 2024
  100. www.sciencedirect.com www.sciencedirect.com
    Inhibition of β2-adrenergic receptor regulates necroptosis in prostate cancer cell
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  148. May 2023
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  184. Jul 2022
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  188. Jun 2022
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  192. May 2022
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  196. Apr 2022
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