396 Matching Annotations
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    can-25-0786-html.html
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  3. aacrjournals.org aacrjournals.org
    Engineering T Cells with a Tumor-Reactive Chimeric T Cell Receptor Reduces Exhaustion and Promotes Persistence to Elicit Enhanced Antitumor Responses
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    aacrjournals.org/cancerres/article/86/11/2688/785304/Engineering-T-Cells-with-a-Tumor-Reactive-Chimeric
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    A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions
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    sciencedirect.com/science/article/pii/S0092867426005830
  5. Jul 2026
  6. 54.241.53.176 54.241.53.176
    Mitochondrial translocation of MDM2 and TFAM reprograms metabolism in treatment-refractory cancers
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  7. Jun 2026
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Driver Mutation Subtypes Differentially Shape Immune Evasion Landscapes in Melanoma: An AI-Driven Inflammatory Pathway Model Implicating CCNE1
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    onlinelibrary.wiley.com/doi/10.1155/humu/6776070
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    ImmTACs overcome cytotoxic T cell suppression
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    biorxiv.org/content/10.64898/2026.03.20.713194v3
  10. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Design and Synthesis of N-Heteroacridone Derivatives and Their Ferroptosis-Inducing Activity Against Human Melanoma
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.202501070
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of Arylsulfatase B and Pembrolizumab in combination on progression of metastatic melanoma in the B16F10 syngeneic mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC13265294/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DGAT1 Inhibition Induces Ferroptosis and Enhances Cancer Immunotherapy Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13266341/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13131504/
  14. May 2026
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    Protocol for validating drug efficacy and safety in scalable 96-well platforms of human cortical organoids and melanoma brain metastases
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    sciencedirect.com/science/article/pii/S2666166726002212
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    Genome-Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515158
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    Chromatin architectures underlying plasmid-based assays for regulatory variant effects
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  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    First GC/MS Profiling and Cytotoxic Evaluation of Physalis acutifolia (Solanaceae) Essential Oils: Insights From Molecular Docking and ADME Predictions
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    Chemical Constituents of Deep-Sea-Derived Fungus Penicillium citrinum W17 and Their Ferroptosis Inhibitory Activity
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  20. aacrjournals.org aacrjournals.org
    Lipid Nanoparticle-Encapsulated mRNAs Encoding Tumor-Specific Toxin Proteins Selectively Target Cancer Cells and Stimulate T Cell Infiltration
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    aacrjournals.org/cancerres/article/85/19/3706/765871/Lipid-Nanoparticle-Encapsulated-mRNAs-Encoding
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    Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer
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  22. Apr 2026
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Moderate-Affinity Antibody–Drug Conjugate Targeting B7-H3 Exerts Potent Antitumor Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13118972/
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    A microbiota-derived bile acid overcomes antibiotic-induced hyporesponsiveness to immune checkpoint therapy by enhancing CD8+ T cell antitumor immunity
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    biorxiv.org/content/10.64898/2026.04.15.718788v1
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PALINCODE: Recording cell lineage with ternary palindromic CRISPR bits
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  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An antibody-drug conjugate designed through clone and isotype selection restricts the growth of CSPG4-expressing triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13096323/
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    The allogeneic FAP-CAR-IL15 iNKT therapy MiNK-215 remodels the tumor stroma to enhance antitumor immunity
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    aacrjournals.org/cancerimmunolres/article/14/2/243/771961/The-Allogeneic-FAP-CAR-IL15-iNKT-Therapy-MiNK-215
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    Universal Nanovial Screening Enables Functional Discovery of Metabolite-Reactive T-Cell Receptors for Cancer Therapy
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  29. 54.241.53.176 54.241.53.176
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    The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity
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    Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs
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    Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome
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    CDK11 inhibition induces cytoplasmic p21 WAF1 splice variant by p53 stabilisation and SF3B1 inactivation
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    THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells
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    Secretome From Human Micro-Fragmented Adipose Tissue Affects In Vitro Monocytes/Macrophages Inflammatory Activity by ICAM-1 Expression
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  38. Mar 2026
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    BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer-Associated Fibroblasts Crosstalk
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    Quantification of Single‐Cell Cysteine Using an Electrochemical Nanosensor for Predicting Tumor Disulfidptosis Susceptibility
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    Sym024 interacts with a unique epitope on the CD73 homodimer, favoring effective bivalent binding to improve anti-PD1 therapy
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    THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells
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  47. Feb 2026
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    A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression
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    The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors
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  56. Jan 2026
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ATAD2 drives melanoma growth and progression and inhibits ferroptosis
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    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    Theranostic Nonstoichiometric, Multivalent Bismuth (Bi)-Based Nanospheres for Selective Spontaneous Melanoma Treatment
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    pubs.acs.org/doi/full/10.1021/acsami.5c20966
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    5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation
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  66. Dec 2025
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    Paeoniflorin Promotes Therapeutic Senescence in Melanoma through Endoplasmic Reticulum Stress and the Calpain1/ERK5/p27 Axis
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    sciencedirect.com/science/article/pii/S0944711325013649
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    Engineered antibodies that stabilize drug-modified KRASG12C neoantigens enable selective and potent cross-HLA immunotherapy
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    nature.com/articles/s41467-025-66132-w
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    Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12712269/
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    Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70169
  72. Nov 2025
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    UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression
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    An immunometabolic prodrug strategy overcomes DHODH inhibitor resistance in refractory melanoma
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    KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2
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    Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs
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    Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells
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    CDK12 inhibition reveals melanoma dependence on the RUNX1/CBFβ complex for genomic stability
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    The lipid droplet protein DHRS3 is a regulator of melanoma cell state
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    pmc.ncbi.nlm.nih.gov/articles/PMC12244328/
  81. Oct 2025
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    High-throughput combination screening of Pidnarulex and other G-quadruplex ligands in multi-cell type tumor spheroids
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    Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3
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    Cannabidivarin directly targets the immunosuppressive activity of regulatory myeloid cells in tumors
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    Systematic design of DMBT1-derived peptides correlating physicochemical properties and sequence motifs with siRNA delivery and efficacy in cancer therapy
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    Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties
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    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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    Inhibiting Cyclin-Dependent Kinase 13-Mediated Nuclear Ubiquitous Casein Kinase and Cyclin-Dependent Kinase Substrate 1 Phosphorylation Facilitates Oxidative Stress-Induced Apoptosis in Melanoma
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    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    CDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma
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    USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization
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  137. May 2025
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  157. Mar 2025
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  169. Feb 2025
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  180. Dec 2024
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  186. Nov 2024
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  193. Oct 2024
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  198. Aug 2024
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  204. Jul 2024
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  210. Jun 2024
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  217. Apr 2024
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