125 Matching Annotations
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    A Mechanistic Dissection of Multifaceted Complement Attack in Age‐Related Macular Degeneration Reveals the Superiority of C3 Inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC13715677/
  3. Oct 2026
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    Differential Modulation of Oxidative Stress and VEGF-A Secretion by Saffron Repron® Pretreatment in ARPE-19 Cells Exposed to High Glucose
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    imrpress.com/journal/FBL/31/10/10.31083/FBL55037
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    Olfactory ensheathing cell-derived extracellular vesicles protect the degenerated retinal pigment epithelium by delivering phagocytosis-related proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC13673258/
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    Factor H polymorphism elevates granzyme B and impairs complement inhibition in human and mouse models
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    sciencedirect.com/science/article/pii/S2589004226033407
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    Dual impact of EZH1/2-targeted therapy in HTLV-1-associated inflammation: Direct and indirect mechanisms
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    sciencedirect.com/science/article/pii/S2589004226031561
  8. Sep 2026
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    Programmed ribosomal frameshifting triggers translational stress to promote viral replication
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    sciencedirect.com/science/article/pii/S0092867426010044
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    s12951-026-04972-4_reference-html.html
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    Triple-costimulatory GD2-CAR T cells incorporating CD28, 4–1BB and CD27 mediate potent cytotoxicity and reduce exhaustion in solid tumour models
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    sciencedirect.com/science/article/pii/S0753332226009339
  12. Aug 2026
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    FOXO6 inhibits SMURF2-mediated ubiquitination and degradation of NR4A1 to promote retinal pigment epithelial cell ferroptosis in diabetic retinopathy
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    onlinelibrary.wiley.com/doi/10.1002/ccs3.70108
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    Activation of AMPK as a therapeutic strategy for FBXL4-related mitochondrial DNA depletion syndrome
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    First-In-Human Trial of Encapsulated Cells Constitutively Expressing Localized IL2 in Patients with High-Grade Serous Ovarian Carcinoma
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  16. Jul 2026
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway
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    A sequential dual-drug delivery system for multi-target inhibition of subretinal fibrosis
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  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deep Proteomic Analysis With Machine Learning Identifies Aqueous Humor Biomarkers of ADAMTSL4-associated Congenital Ectopia Lentis
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    Microglia-derived exosomal miR-31-5p promotes type 2 diabetic retinopathy by impairing physiological angiogenesis homeostasis
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  21. Jun 2026
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLGA Nanoparticles Restore Acidic pH and Degradative Function to Compromised Lysosomes with Cy3-Labeling Providing Enhanced Tracking to Lysosomes
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  23. May 2026
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    Proximity labeling proteomics maps radial glial ciliary proteins across the developing telencephalon
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  25. Apr 2026
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    In Vitro Ocular Cytotoxicity of BEE Venom in ARPE-19, NTM5, HCET, and HCEC-12 Cell Lines
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  27. Mar 2026
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    UC2288 decreases the viability and metastatic activity of human Uveal melanoma cells via activating the AMPK/eIF2/ATF4 ER stress axis
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    Synthesis and characterization of an injectable telechelic material for the epiretinal delivery of retinal gene therapies
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  31. Feb 2026
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    Disintegrin Rhodostomin Mutant Ameliorates the Severity of Experimental Proliferative Vitreoretinopathy by Suppressing Both Integrin αvβ3 and α5β1
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    Antiproliferative Activity of α-Tocopherol, γ-Tocopherol and Tocotrienols and Their Drug Interactions Evaluated Using Loewe and Chou–Talalay Models in HeLa and MCF-7 Cancer Cell Lines
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    NuSAP Safeguards Centriole Integrity to Mediate CEP57-CEP152 Torus Recruitment for Proper Engagement
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    Fucoidan from Fucus vesiculosus Protects Retinal Pigment Epithelium from Lipid-Induced Damage Related to AMD
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    Bortezomib Inhibits Cellular Proliferation and Inflammation in a Mouse Model of Proliferative Vitreoretinopathy
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    Dapagliflozin prevents methylglyoxal-induced retinal cell death in ARPE-19 cells
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    B7-H3 and GD2 overexpression as immunotherapeutic targets in retinoblastoma
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  39. Jan 2026
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    Differential contribution of TFE3 isoforms to cell motility and invasion
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    PEP-TP56 enhances AAV transduction in a serotype-independent manner
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    The rs713586 risk variant dysregulates ADCY3 rather than DNAJC27, leading to obesity through ZFP42-TET1-mediated DNA methylation
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  43. Dec 2025
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    LAMP2A regulates endosomal protein composition and membrane identity in exosome biogenesis
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  46. Sep 2025
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    ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chains
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    PDZK1 Protects Against RPE Senescence by Targeting the 14-3-3ε-mTOR Axis to Attenuate Early Diabetic Retinopathy
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    Evaluating Flavoprotein Fluorescence Imaging as a Biomarker of Early Retinal Ganglion Cell Mitochondrial Stress
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    CRISPR-Cas13d-Mediated Targeting of a Context-Specific Essential Gene Enables Selective Elimination of Uveal Melanoma
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  51. Jul 2025
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    The HCMV tegument protein UL88 degrades MyD88 and reduces innate immune activation
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    The GATE glycoprotein complex enhances human cytomegalovirus entry in endothelial cells
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    The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITA
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  55. Jun 2025
  56. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Magnetically Controllable and Degradable Milliscale Swimmers as Intraocular Drug Implants
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  57. May 2025
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    PRL3-zumab as an anti-angiogenic therapy in neovascular eye diseases
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    Structural basis of human cytomegalovirus neutralization by gB AD-5-specific potent antibodies
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    Heterogeneity of late endosome/lysosomes shown by multiplexed DNA-PAINT imaging
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  61. Apr 2025
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    Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage
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    RAF1 kinase contributes to autophagic lysosome reformation
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    The Role of Lactate Metabolism in Retinoblastoma Tumorigenesis and Ferroptosis Resistance
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    Leveraging AAV1-Rac1T17N to prevent experimental proliferative vitreoretinopathy
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  66. Mar 2025
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    PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover
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    Engineering mtDNA deletions by reconstituting end joining in human mitochondria
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  69. Feb 2025
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    Influence of a Very High-Molecular Weight Fucoidan from Laminaria hyperborea on Age-Related Macular Degeneration-Relevant Pathomechanisms in Ocular Cell Models
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  71. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype
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  73. Jan 2025
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    Arginase Activity Inhibition With Thymoquinone Induces a Hybrid Type of Cell‐Death in MDA‐MB‐231 Cell Line
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  75. Dec 2024
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    Antioxidant properties of the soluble carotenoprotein AstaP and its feasibility for retinal protection against oxidative stress
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  77. Nov 2024
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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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  79. Sep 2024
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    Targeting ALDOA to Modulate Tumorigenesis and Energy Metabolism in Retinoblastoma
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  82. Aug 2024
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    Decoupling global biases and local interactions between cell biological variables
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  84. May 2024
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    Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics
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  86. Apr 2024
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    Circ_0053943 complexed with IGF2BP3 drives uveal melanoma progression via regulating N6-methyladenosine modification of Epidermal growth factor receptor
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  89. Mar 2024
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    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
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    Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen
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  93. Feb 2024
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    Targeting ABCG1 and SREBP-2 mediated cholesterol homeostasis ameliorates Zika virus induced ocular pathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC10884761/
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    qTAG: An adaptable CRISPR-based endogenous tagging protocol using optimized repair cassettes.
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  96. Jan 2024
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    Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection
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    Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19
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  100. Sep 2023
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    Hyperglycemia-regulated tRNA-derived fragment tRF-3001a propels neurovascular dysfunction in diabetic mice
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  102. Aug 2023
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    Gentiopicroside inhibits retinoblastoma cell proliferation, invasion, and tumorigenesis in nude mice by suppressing the PI3K/AKT pathway
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  104. Jul 2023
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    Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics
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  106. Jun 2023
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Promotion of axon regeneration and protection on injured retinal ganglion cells by rCXCL2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10280836/
  108. May 2023
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    MYO10 regulates genome stability and cancer inflammation through mediating mitosis
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    Comparison of Fucoidans from Saccharina latissima Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium
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  111. Apr 2023
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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  113. Jan 2023
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    A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
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  115. Nov 2022
  116. aacrjournals.org aacrjournals.org
    Potent and selective PTDSS1 inhibitors induce collateral lethality in cancers with PTDSS2 deletion
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    aacrjournals.org/cancerres/article/82/21/4031/709946/Potent-and-Selective-PTDSS1-Inhibitors-Induce
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    m6A modification of circSPECC1 suppresses RPE oxidative damage and maintains retinal homeostasis
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  118. Oct 2022
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