83 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A hotspot phosphorylation site on SHP2 drives oncoprotein activation and drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13066003/
  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Characterization of Drug-Tolerant Persister Cells in Triple-Negative Breast Cancer Identifies a Shared Persistence Program across Treatments and Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618426/
  5. Jan 2026
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    Notch1 regulates Orai1 and Orai3 expression in breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12830608/
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    CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction
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    nature.com/articles/s41467-025-67865-4
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    Growth factors maintain intratumoral heterogeneity and drive therapeutic resistance in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124725015980
  9. Dec 2025
  10. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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    CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling
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    sciencedirect.com:5037/science/article/pii/S2211124725014482
  12. Oct 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523003/
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    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511349
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    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  16. Sep 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12340909/
  18. Aug 2025
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    Building simplified cancer subtyping and prediction models with glycan gene signatures
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    sciencedirect.com/science/article/pii/S2667237525001766
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    A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262427/
  21. Jul 2025
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    Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis
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    sciencedirect.com/science/article/pii/S2666379125003258
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
  24. Jun 2025
  25. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  26. Apr 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer
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  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons
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  29. Mar 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induction of Triple-Negative Breast Cancer Cell Death and Chemosensitivity Using mTORC2-Directed RNAi Nanomedicine
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    Adhesion strength of tumor cells predicts metastatic disease in vivo
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  32. Feb 2025
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  34. Jan 2025
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    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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  37. Dec 2024
  38. www.cell.com www.cell.com
    MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity
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    cell.com/cell-reports/abstract/S2211-1247(24)01471-2
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    mLumiOpto Is a Mitochondrial-Targeted Gene Therapy for Treating Cancer
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  40. Nov 2024
  41. www.biorxiv.org www.biorxiv.org
    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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  42. Sep 2024
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    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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  44. Jul 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes
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  46. Mar 2024
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    Identification and characterization of a potent and selective HUNK inhibitor for treatment of HER2+ breast cancer
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    sciencedirect.com/science/article/pii/S2451945624000370
  48. Feb 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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  52. Oct 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM21 mediates the synergistic effect of Olaparib and Sorafenib by degrading BRCA1 through ubiquitination in TNBC
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    ncbi.nlm.nih.gov/pmc/articles/PMC10589312/
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    ETHE1 Accelerates Triple-Negative Breast Cancer Metastasis by Activating GCN2/eIF2α/ATF4 Signaling
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    mdpi.com/1422-0067/24/19/14566
  55. Sep 2023
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    miR-770-5p regulates EMT and invasion in TNBC cells by targeting DNMT3A
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    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
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  58. Jul 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10368911/
  60. Jun 2023
  61. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    nature.com/articles/s41467-023-39241-7
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα/LKB1 complex upregulates E-cadherin expression and stimulates breast cancer growth and progression upon adiponectin exposure
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34626
  63. Feb 2023
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9881645/
  65. Dec 2022
  66. www.nature.com www.nature.com
    Table 1 Tumor cell lines used to set up common subcutaneous mouse tumor models
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    nature.com/articles/s41596-022-00709-3/tables/1
  67. Nov 2022
  68. aacrjournals.org aacrjournals.org
    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
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    aacrjournals.org/cancerrescommun/article/2/11/1388/710518/DDR2-Coordinates-EMT-and-Metabolic-Reprogramming
  69. May 2022
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiosensitivity of Breast Cancer Cells Is Dependent on the Organ Microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC9134193/
  71. Apr 2022
  72. www.sciencedirect.com www.sciencedirect.com
    Generation and application of TGFβ-educated human Vγ9Vδ2 T cells
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  73. Mar 2022
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    An optimized protocol for PD-L1 pathological assessment with patient sample deglycosylation to improve correlation with therapeutic response
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  75. Feb 2022
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    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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  77. Dec 2021
  78. www.sciencedirect.com www.sciencedirect.com
    TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer
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  79. Nov 2021
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    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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    Interplay between protein acetylation and ubiquitination controls MCL1 protein stability
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  83. Oct 2021
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    Analysis of clonogenic growth in vitro
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  85. Sep 2021
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    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
  87. Aug 2021
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AKR1B10 promotes breast cancer cell proliferation and migration via the PI3K/AKT/NF-κB signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC8379827/
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    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S2405471219303874
  90. Jul 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy
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    Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion
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    Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer
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  94. May 2021
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    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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    Deciphering the signaling network of breast cancer improves drug sensitivity prediction
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  97. Apr 2021
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    The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    sciencedirect.com/science/article/pii/S1550413120305453
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8384339/
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    miR-770-5p regulates EMT and invasion in TNBC cells by targeting DNMT3A
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  102. Mar 2021
  103. www.sciencedirect.com www.sciencedirect.com
    Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer
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  104. Feb 2021
  105. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness
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    biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00710-5
  106. cancerres.aacrjournals.org cancerres.aacrjournals.org
    3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer
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    cancerres.aacrjournals.org/content/81/4/847
  107. Nov 2020
  108. www.sciencedirect.com www.sciencedirect.com
    G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
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  109. Oct 2020
  110. www.cell.com www.cell.com
    Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing
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    cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
  111. Sep 2020
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX11 promotes epithelial/mesenchymal hybrid state and alters tropism of invasive breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7518891/
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    NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay
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    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
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    sciencedirect.com/science/article/pii/S0092867420306863
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    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719317139
  117. Jan 2020
  118. www.sciencedirect.com www.sciencedirect.com
    VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells
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    Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
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    sciencedirect.com/science/article/pii/S2451945619301746
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    Untitled document
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    sciencedirect.com/science/article/pii/S1534580719302990
  121. Nov 2018
  122. www.sciencedirect.com www.sciencedirect.com
    JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
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    sciencedirect.com/science/article/pii/S1550413117306691
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    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    sciencedirect.com/science/article/pii/S1097276518305999
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    Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer
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  125. www.sciencedirect.com www.sciencedirect.com
    lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer
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    sciencedirect.com/science/article/pii/S1535610818301107
  126. Nov 2017
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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