157 Matching Annotations
  1. Last 7 days
  2. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Dual Pro-Angiogenic and Pro-Fibrotic MARCO+ Microglial Phenotype in Diabetic Retinopathy
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202502138R
  3. Aug 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12339548/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12325413/
  6. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70102
  7. Jul 2025
  8. www.sciencedirect.com www.sciencedirect.com
    Treadmill Exercise Alleviates STING-mediated Microglia Pyroptosis and Polarization via Activating Mitophagy post-TBI
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    sciencedirect.com/science/article/pii/S0891584925008494
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Blood–brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12220692/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fat mass and obesity–mediated N6-methyladenosine modification modulates neuroinflammatory responses after traumatic brain injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC12220718/
  11. Jun 2025
  12. journals.lww.com journals.lww.com
    M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury
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    journals.lww.com/nrronline/fulltext/2022/05000/m1_type_microglia_can_induce_astrocytes_to_deposit.34.aspx
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    sciencedirect.com/science/article/pii/S2211124725006928
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    Inhibition of phosphodiesterase-4 by rolipram alleviates anxiety-like behavior in mice with PTSD by modulating neuroinflammation and synaptic plasticity via cAMP signaling
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    sciencedirect.com/science/article/pii/S1567576925011063
  15. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70108
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Murine norovirus allosteric escape mutants mimic gut activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12172446/
  17. May 2025
  18. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500334R
  19. www.sciencedirect.com www.sciencedirect.com
    Poliumoside alleviates microglia-mediated inflammation and blood-brain barrier disruption via modulating the polarization of microglia after ischemic stroke in mice
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    sciencedirect.com/science/article/pii/S0944711325005197
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prostaglandin endoperoxide synthase 2 regulates neuroinflammation to mediate postoperative cognitive dysfunction in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089394/
  21. www.sciencedirect.com www.sciencedirect.com
    Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1074761325001815
  22. Apr 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targeting the RdRp of norovirus
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969896/
  24. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    S-ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide-Induced Depression Via Targeting SIRT2
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202416481
  25. Mar 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A microglia clonal inflammatory disorder in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908784/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dopamine D1 receptor agonist alleviates post-weaning isolation-induced neuroinflammation and depression-like behaviors in female mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11895232/
  28. www.biorxiv.org www.biorxiv.org
    Glioma-induced DNMT3A-dependent reduction of DNA methylation in microglia promotes a transient anti-tumoral phenotype
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    biorxiv.org/content/10.1101/2025.02.22.639606v1
  29. journals.lww.com journals.lww.com
    Pharmacological targeting cGAS/STING/NF-κB axis by... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2025/11000/pharmacological_targeting_cgas_sting_nf__b_axis_by.31.aspx
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Machine learning-assisted design of immunomodulatory lipid nanoparticles for delivery of mRNA to repolarize hyperactivated microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11878168/
  31. Feb 2025
  32. www.sciencedirect.com www.sciencedirect.com
    Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation
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    sciencedirect.com/science/article/pii/S0925443925000821
  33. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17344
  34. Jan 2025
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11759022/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions
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    pmc.ncbi.nlm.nih.gov/articles/PMC11743796/
  37. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Actions of dexmedetomidine in regulating NLRP3 in postoperative cognitive dysfunction in aged mice via the autophagy–lysosome pathway
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17378
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nogo-A exacerbates sepsis-associated encephalopathy by modulating microglial SHP-2/NLRP3 balance and inducing ROS and M1 polarization
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    pmc.ncbi.nlm.nih.gov/articles/PMC11647263/
  39. Dec 2024
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exosome-based therapies for inflammatory disorders: a review of recent advances
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    pmc.ncbi.nlm.nih.gov/articles/PMC11657721/
  41. www.sciencedirect.com www.sciencedirect.com
    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    sciencedirect.com/science/article/pii/S1074761324005132
  42. www.sciencedirect.com www.sciencedirect.com
    Selenoprotein P is a target for regulating extracellular vesicle biogenesis and secretion from activated microglia in vivo
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    sciencedirect.com/science/article/pii/S2211124724013767
  43. Nov 2024
  44. www.sciencedirect.com www.sciencedirect.com
    Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis
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    sciencedirect.com/science/article/pii/S1550413124004029
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539848/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TREM-1 mediates interaction between substantia nigra microglia and peripheral neutrophils
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    ncbi.nlm.nih.gov/pmc/articles/PMC11467918/
  47. Oct 2024
  48. www.sciencedirect.com www.sciencedirect.com
    Phytochemical constituents from root barks of Eleutherococcus henryi Oliv. and their anti-neuroinflammatory effect
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    sciencedirect.com/science/article/pii/S0378874124011760
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433893/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433905/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC11438333/
  52. Sep 2024
  53. www.sciencedirect.com www.sciencedirect.com
    Transcriptome analysis unveils PLSCR1 associated with microglial polarization in neuropathic pain
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    sciencedirect.com/science/article/pii/S0378111924008424
  54. Aug 2024
  55. www.sciencedirect.com www.sciencedirect.com
    Prolonged extracellular low sodium concentrations and subsequent their rapid correction modulate nitric oxide production dependent on NFAT5 in microglia
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    sciencedirect.com/science/article/pii/S0891584924006063
  56. journals.lww.com journals.lww.com
    Exosomes derived from microglia overexpressing miR-124-3p alleviate neuronal endoplasmic reticulum stress damage after repetitive mild traumatic brain injury
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    journals.lww.com/nrronline/fulltext/2024/09000/exosomes_derived_from_microglia_overexpressing.33.aspx
  57. Jul 2024
  58. www.mdpi.com www.mdpi.com
    Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord
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    mdpi.com/1422-0067/25/13/7168
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ID2-ETS2 axis regulates the transcriptional acquisition of pro-tumoral microglia phenotype in glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11255298/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular vesicles released from microglia after palmitate exposure impact brain function
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    ncbi.nlm.nih.gov/pmc/articles/PMC11253458/
  61. www.sciencedirect.com www.sciencedirect.com
    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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    sciencedirect.com/science/article/pii/S2211124724007460
  62. May 2024
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Accumulation of extracellular elastin-derived peptides disturbed neuronal morphology and neuron–microglia crosstalk in aged brain
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16039
  64. www.sciencedirect.com www.sciencedirect.com
    Cannabidiol prevents LPS-induced inflammation by inhibiting the NLRP3 inflammasome and iNOS activity in BV2 microglia cells via CB2 receptors and PPARγ
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    sciencedirect.com/science/article/pii/S0197018624000962
  65. Apr 2024
  66. link.springer.com link.springer.com
    Lactate Protects Microglia and Neurons from Oxygen–Glucose Deprivation/Reoxygenation
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    link.springer.com/article/10.1007/s11064-024-04135-7
  67. Mar 2024
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960275/
  69. Feb 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The reversible activation of norovirus by metal ions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878237/
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke reperfusion injury with the progression of acute ischaemic stroke
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16058
  72. www.mdpi.com www.mdpi.com
    Neuroprotection via Carbon Monoxide Depends on the Circadian Regulation of CD36-Mediated Microglial Erythrophagocytosis in Hemorrhagic Stroke
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    mdpi.com/1422-0067/25/3/1680
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activated microglia release β−galactosidase that promotes inflammatory neurodegeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811154/
  74. Jan 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three methods for examining the de novo proteome of microglia using BONCAT bioorthogonal labeling and FUNCAT click chemistry
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    ncbi.nlm.nih.gov/pmc/articles/PMC10511912/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The COP9 signalosome reduces neuroinflammation and attenuates ischemic neuronal stress in organotypic brain slice culture model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10439869/
  77. Dec 2023
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10749599/
  79. www.sciencedirect.com www.sciencedirect.com
    Diosmin ameliorates LPS-induced depression-like behaviors in mice: inhibition of inflammation and oxidative stress in the prefrontal cortex
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    sciencedirect.com/science/article/pii/S036192302300268X
  80. elifesciences.org elifesciences.org
    Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer’s disease
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    elifesciences.org/articles/85279
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10687467/
  82. Oct 2023
  83. www.mdpi.com www.mdpi.com
    Oncolytic Viral Therapy for Glioma by Recombinant Sindbis Virus
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    mdpi.com/2072-6694/15/19/4738
  84. Jul 2023
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclo (MQCNS) has the potential to treat ischemic stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC10360098/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vav1 promotes inflammation and neuronal apoptosis in cerebral ischemia/reperfusion injury by upregulating microglial and NLRP3 inflammasome activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10360116/
  87. www.sciencedirect.com www.sciencedirect.com
    Low and high doses of oral maslinic acid protect against Parkinson’s disease via distinct gut microbiota-related mechanisms
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    sciencedirect.com/science/article/pii/S0753332223008910
  88. May 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The neuroprotective N-terminal amyloid-β core hexapeptide reverses reactive gliosis and gliotoxicity in Alzheimer’s disease pathology models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10225108/
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PERK-Mediated Cholesterol Excretion from IDH Mutant Glioma Determines Anti-Tumoral Polarization of Microglia
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    onlinelibrary.wiley.com/doi/10.1002/advs.202205949
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Poly(ADP-ribose) polymerase family member 14 promotes... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154507/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exendin-4 and linagliptin attenuate neuroinflammation in a... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154509/
  93. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16058
  94. Apr 2023
  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Degradation of NLRP3 by p62-dependent-autophagy improves cognitive function in Alzheimer's disease by maintaining the phagocytic function of microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC10493665/
  96. Mar 2023
  97. www.sciencedirect.com www.sciencedirect.com
    Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner
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    sciencedirect.com/science/article/pii/S2211124723001900
  98. link.springer.com link.springer.com
    Necrostatin-1S mitigates type-2 diabetes-associated cognitive decrement and lipotoxicity-induced neuro-microglia changes through p-RIPK-RIPK3-p-MLKL axis
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    link.springer.com/article/10.1007/s11011-023-01185-8
  99. link.springer.com link.springer.com
    KDM4A, involved in the inflammatory and oxidative stress caused by traumatic brain injury-hemorrhagic shock, partly through the regulation of the microglia M1 polarization
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    link.springer.com/article/10.1186/s12868-023-00784-6
  100. Feb 2023
  101. www.sciencedirect.com www.sciencedirect.com
    The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microglia
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    sciencedirect.com/science/article/pii/S2589004223000706
  102. link.springer.com link.springer.com
    Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6
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    link.springer.com/article/10.1007/s12035-023-03232-y
  103. Jan 2023
  104. journals.lww.com journals.lww.com
    Emodin attenuates inflammation and demyelination in... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/07000/Emodin_attenuates_inflammation_and_demyelination.27.aspx
  105. onlinelibrary.wiley.com onlinelibrary.wiley.com
    P2Y6 receptor-dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging
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    onlinelibrary.wiley.com/doi/10.1111/acel.13761
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15751
  107. www.sciencedirect.com www.sciencedirect.com
    Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes
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    sciencedirect.com/science/article/pii/S0896627322010820
  108. Dec 2022
  109. journals.lww.com journals.lww.com
    Microglial depletion impairs glial scar formation and... : Neural Regeneration Research
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