171 Matching Annotations
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    Brain-Derived Neurotrophic Factor and Heat Shock Protein-32: Potential Targets for Microglial Response to Glucose and Oxygen Manipulation
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    link.springer.com/article/10.1007/s12035-025-05378-3
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    Low-Intensity Pulsed Ultrasound Attenuates Neuroinflammation and Preserves Synaptic Integrity by Modulating Microglial Polarization Through the MAPK–NF-κB Pathway After Traumatic Brain Injury
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  5. Dec 2025
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    Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control
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  7. Nov 2025
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    High Extracellular Glucose Concentration Drives Palmitate-Induced Toxicity and Metabolic Dysfunction in BV2 Microglia Cells
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    Cathepsin B overexpression and lysosomal leakage in inflammatory microglia promote neuroinflammation in olfactory dysfunction by triggering mitochondrial dysfunction and pyroptosis
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    Design, synthesis, and evaluation of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties
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    The involvement of microglia and the CXCL16-CXCR6 axis in the recruitment of CD8+ T cells to an amyloidogenic mouse brain
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  13. Oct 2025
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    GPR40 agonist ameliorates neurodegeneration by regulating mitochondria dysfunction and NLRP3 inflammasome in Alzheimer’s disease animal models
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    From Molecular Docking to Rat Models: Butyrate From a High-Fiber Diet Inhibits HDAC1 and NLRP3 Inflammasome to Alleviate Oxidative Stress and Inflammation After Spinal Cord Injury
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    14-3-3 Proteins Negatively Regulate Microglial Activation via Inhibition of the NF-κB Pathway
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    Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia
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    Dual Pro-Angiogenic and Pro-Fibrotic MARCO+ Microglial Phenotype in Diabetic Retinopathy
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  20. Aug 2025
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    Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer
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    Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity
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  24. Jul 2025
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    Treadmill Exercise Alleviates STING-mediated Microglia Pyroptosis and Polarization via Activating Mitophagy post-TBI
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    Blood–brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis
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    Fat mass and obesity–mediated N6-methyladenosine modification modulates neuroinflammatory responses after traumatic brain injury
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  28. Jun 2025
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    M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    Inhibition of phosphodiesterase-4 by rolipram alleviates anxiety-like behavior in mice with PTSD by modulating neuroinflammation and synaptic plasticity via cAMP signaling
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    Murine norovirus allosteric escape mutants mimic gut activation
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  34. May 2025
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    Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia
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    Prostaglandin endoperoxide synthase 2 regulates neuroinflammation to mediate postoperative cognitive dysfunction in mice
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    Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer’s disease
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  39. Apr 2025
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    Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targeting the RdRp of norovirus
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    Dopamine D1 receptor agonist alleviates post-weaning isolation-induced neuroinflammation and depression-like behaviors in female mice
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    Glioma-induced DNMT3A-dependent reduction of DNA methylation in microglia promotes a transient anti-tumoral phenotype
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    Pharmacological targeting cGAS/STING/NF-κB axis by... : Neural Regeneration Research
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  48. Feb 2025
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    Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation
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  51. Jan 2025
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    The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson’s disease
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    Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions
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    Actions of dexmedetomidine in regulating NLRP3 in postoperative cognitive dysfunction in aged mice via the autophagy–lysosome pathway
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  56. Dec 2024
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    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    Selenoprotein P is a target for regulating extracellular vesicle biogenesis and secretion from activated microglia in vivo
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  60. Nov 2024
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    Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis
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    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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  64. Oct 2024
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    Phytochemical constituents from root barks of Eleutherococcus henryi Oliv. and their anti-neuroinflammatory effect
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    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
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    Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model
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    Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming
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  69. Sep 2024
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    Transcriptome analysis unveils PLSCR1 associated with microglial polarization in neuropathic pain
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  71. Aug 2024
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    Prolonged extracellular low sodium concentrations and subsequent their rapid correction modulate nitric oxide production dependent on NFAT5 in microglia
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    Exosomes derived from microglia overexpressing miR-124-3p alleviate neuronal endoplasmic reticulum stress damage after repetitive mild traumatic brain injury
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  74. Jul 2024
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    Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord
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    ID2-ETS2 axis regulates the transcriptional acquisition of pro-tumoral microglia phenotype in glioma
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    Extracellular vesicles released from microglia after palmitate exposure impact brain function
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    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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  79. May 2024
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    Accumulation of extracellular elastin-derived peptides disturbed neuronal morphology and neuron–microglia crosstalk in aged brain
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    Cannabidiol prevents LPS-induced inflammation by inhibiting the NLRP3 inflammasome and iNOS activity in BV2 microglia cells via CB2 receptors and PPARγ
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  82. Apr 2024
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    Lactate Protects Microglia and Neurons from Oxygen–Glucose Deprivation/Reoxygenation
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  84. Mar 2024
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    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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  86. Feb 2024
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    The reversible activation of norovirus by metal ions
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    Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke reperfusion injury with the progression of acute ischaemic stroke
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    Neuroprotection via Carbon Monoxide Depends on the Circadian Regulation of CD36-Mediated Microglial Erythrophagocytosis in Hemorrhagic Stroke
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    Activated microglia release β−galactosidase that promotes inflammatory neurodegeneration
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  91. Jan 2024
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three methods for examining the de novo proteome of microglia using BONCAT bioorthogonal labeling and FUNCAT click chemistry
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    The COP9 signalosome reduces neuroinflammation and attenuates ischemic neuronal stress in organotypic brain slice culture model
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  94. Dec 2023
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis
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    Diosmin ameliorates LPS-induced depression-like behaviors in mice: inhibition of inflammation and oxidative stress in the prefrontal cortex
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    Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer’s disease
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    LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation
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  99. Oct 2023
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    Oncolytic Viral Therapy for Glioma by Recombinant Sindbis Virus
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  101. Jul 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclo (MQCNS) has the potential to treat ischemic stroke
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    Vav1 promotes inflammation and neuronal apoptosis in cerebral ischemia/reperfusion injury by upregulating microglial and NLRP3 inflammasome activation
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    Low and high doses of oral maslinic acid protect against Parkinson’s disease via distinct gut microbiota-related mechanisms
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  105. May 2023
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The neuroprotective N-terminal amyloid-β core hexapeptide reverses reactive gliosis and gliotoxicity in Alzheimer’s disease pathology models
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    PERK-Mediated Cholesterol Excretion from IDH Mutant Glioma Determines Anti-Tumoral Polarization of Microglia
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    onlinelibrary.wiley.com/doi/10.1002/advs.202205949
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    sciencedirect.com/science/article/pii/S0896627318300564
  218. europepmc.org europepmc.org
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    europepmc.org/articles/PMC5659819/
  219. Nov 2017
  220. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14144/full
  221. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ischemia‐responsive protein 94 is a key mediator of ischemic neuronal injury‐induced microglial activation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14111/full
  222. www.sciencedirect.com www.sciencedirect.com
    TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss
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    sciencedirect.com/science/article/pii/S0896627317304750
  223. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The role of autophagy in pro‐inflammatory responses of microglia activation via mitochondrial reactive oxygen species in vitro
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14042/full