231 Matching Annotations
  1. Sep 2026
  2. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1002/prp2.70317
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    A designer saxitoxin-engineered sodium channel pair as a general tool for subtype-selective inhibition
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    sciencedirect.com/science/article/pii/S2451945626001959
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70329
  5. dx.doi.org dx.doi.org
    Off-Target Activation of CatSper Limits the Utility of a Novel Small Molecule Slo3 Inhibitor and its Derivatives in Human Sperm
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    dx.doi.org/10.1021/acsptsci.6c00091
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AHA1 Regulates Aβ Production via Modulation of APP Abundance and γ‐Secretase Assembly
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    pmc.ncbi.nlm.nih.gov/articles/PMC13522734/
  7. Aug 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AI-enabled discovery and biochemical optimization of minibinders targeting cancer cell-surface proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC13494018/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Humanized antibody-drug conjugates for Somatostatin receptor 2 (SSTR2)-positive tumor treatment
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    pmc.ncbi.nlm.nih.gov/articles/PMC13477831/
  10. Jul 2026
  11. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70570
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective treatment of human breast tumors by chimeric CCL2 and CCL8 diphtheria toxin cytotoxic peptides
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    pmc.ncbi.nlm.nih.gov/articles/PMC13336256/
  13. www.biorxiv.org www.biorxiv.org
    APP-CTFβ/C99 oligomers drive synaptic vesicle tethering through C-terminal interactions
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    biorxiv.org/content/10.64898/2026.06.25.734451v1
  14. www.tandfonline.com www.tandfonline.com
    Effective treatment of human breast tumors by chimeric CCL2 and CCL8 diphtheria toxin cytotoxic peptides
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    tandfonline.com/doi/full/10.1080/15384047.2026.2688479
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    Glycoform engineering of a mammalian platform to sculpt a humanized recombinant bioscavenger
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    sciencedirect.com/science/article/pii/S2405471226001377
  16. Jun 2026
  17. elifesciences.org elifesciences.org
    Nanoscopy Reveals Heparan Sulfate Clusters as Docking Sites for SARS-CoV-2 Attachment and Entry
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    elifesciences.org/reviewed-preprints/108925v1
  18. aacrjournals.org aacrjournals.org
    LM-101, an anti-SIRPα antibody, in patients with relapsed/refractory lymphoma and advanced head and neck cancer: an open-label, multicenter, phase 1 trial
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    aacrjournals.org/clincancerres/article/32/12/2391/785685/LM-101-an-Anti-SIRP-Antibody-in-Patients-with
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    Erythroferrone antagonism of BMPs is governed by a composite heparin-binding motif
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    sciencedirect.com/science/article/pii/S0021925826021228
  20. May 2026
  21. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70498
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    Comparative analysis reveals molecular adaptation of mammalian HCA2 to microbial metabolites
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    sciencedirect.com/science/article/pii/S2589004226014057
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    Cannabinoid CB2 receptor drives trastuzumab resistance and predicts durable anti-HER2 response
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    nature.com/articles/s41388-026-03814-9
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Natural xanthones as α-Mangostin induce vasorelaxation involving key gating residues in the S6 domain of BK channels
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    pmc.ncbi.nlm.nih.gov/articles/PMC13148824/
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70479
  26. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel selective stabilizer of the ryanodine receptor 2 prevents stress-induced ventricular arrhythmias without impairing cardiac function
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70459
  27. Apr 2026
  28. aacrjournals.org aacrjournals.org
    Conditionally Active CD28xVISTA Bispecific Antibodies Promote Myeloid-Driven T-Cell Activation
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    aacrjournals.org/cancerimmunolres/article/13/12/1956/768327/Conditionally-Active-CD28xVISTA-Bispecific
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70432
  30. www.sciencedirect.com www.sciencedirect.com
    Rationally designed light-inducible RNA-releasing protein for translational regulation and optogenetic control of gene therapies
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    sciencedirect.com/science/article/pii/S0167779926000892
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PAR-2 with a negative allosteric modulator increases tumor antigen presentation and potentiates anti-PD-1 immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13052617/
  32. aacrjournals.org aacrjournals.org
    SDP-LIV1, a Novel and Optimized LIV-1 Antibody-drug Conjugate Demonstrating Superior Anti-Tumor Efficacy and Favorable Safety Profile for Treatment of Solid Tumors
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    aacrjournals.org/mct/article/25/2/322/771935/SDP-LIV1-a-Novel-and-Optimized-LIV-1-Antibody-Drug
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70367
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  35. Mar 2026
  36. 54.241.53.176 54.241.53.176
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  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differential state-dependent Nav1.8 inhibition by suzetrigine, LTGO-33, and A-887826
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    pmc.ncbi.nlm.nih.gov/articles/PMC11938940/
  38. www.science.org www.science.org
    IL-7/IL-15/IL-21 cytokine-fusion scaffold generates highly functional CAR T cells enriched in long-lived T memory stem cells
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    science.org/doi/10.1126/sciadv.aec2632
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histamine H1 Receptor-Mediated CREB Phosphorylation via Gq Protein Signaling and Arrestin Modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12943045/
  40. Feb 2026
  41. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Structure-Based Discovery of Obeticholic Acid Derivatives as Novel Farnesoid X Receptor Partial Agonists with Improved Selectivity and Reduced Off-Target Effects
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202500960
  42. Jan 2026
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Native CFTR codon bias controls translation rate to balance off-pathway aggregation and channel function by conformational imprinting
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    pmc.ncbi.nlm.nih.gov/articles/PMC12800165/
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    Engineering and Translational Evaluation of A Novel Albumin-binding Variable Domain of Heavy chain-only Antibody for Half-life Extension
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    sciencedirect.com/science/article/pii/S1773224726000699
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    An Exploratory Study of the Impact of a CCL21-Derived C-Terminal Peptide on Dendritic Cell Lymph Node Homing
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    onlinelibrary.wiley.com/doi/10.1155/jimr/8833079
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL
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    pmc.ncbi.nlm.nih.gov/articles/PMC12795454/
  47. Dec 2025
  48. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation
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    sciencedirect.com:5037/science/article/pii/S221112472501530X
  49. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    miRNA modules for precise, tunable control of gene expression
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    sciencedirect.com:5037/science/article/pii/S1097276525009694
  50. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors
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    sciencedirect.com:5037/science/article/pii/S1097276525009372
  51. 54.241.53.176 54.241.53.176
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  52. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70245
  53. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Sec61 translocon inhibitor flavitransin blocks selectively dengue virus polyprotein insertion in the ER with pan-orthoflavivirus antiviral potency
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    sciencedirect.com:5037/science/article/pii/S2211124725014147
  54. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Combination of two Na+ channel-inhibiting anticonvulsants lacosamide and phenytoin: An additive, synergistic, or antagonistic effect?
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    sciencedirect.com:5037/science/article/pii/S0006295225008688
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Interactions between Siglec-10 and α3β1 Integrin Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12671567/
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    Selective decoupling of IgG1 binding to viral Fc receptors restores antibody-mediated NK cell activation against HCMV
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    sciencedirect.com:5037/science/article/pii/S2211124725013658
  57. Nov 2025
  58. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Identification of small molecule ligands for GPR83 which modulate morphine antinociception and reward
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    sciencedirect.com:5037/science/article/pii/S0026895X25157520
  59. www.sciencedirect.com www.sciencedirect.com
    Endothelin-converting enzyme 2 regulates κ opioid receptor trafficking and function
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    sciencedirect.com/science/article/pii/S0022356525402638
  60. www.biorxiv.org www.biorxiv.org
    A chemogenetic ligand-receptor pair for voltage-gated sodium channel subtype-selective inhibition
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    biorxiv.org/content/10.1101/2025.11.03.686046v1
  61. Oct 2025
  62. www.biorxiv.org www.biorxiv.org
    A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function
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    biorxiv.org/content/10.1101/2025.10.14.682336v1
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antineoplastic Activity of a Novel Trispecific Single-Chain Antibody Targeting the hERG1/β1 Integrin Complex and TRAIL Receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485380/
  64. Sep 2025
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The GLP-1 analogue, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618104/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12373499/
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    Development of a cyst-targeted therapy for polycystic kidney disease using an antagonistic dimeric IgA monoclonal antibody against cMET
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    sciencedirect.com/science/article/pii/S2666379125004082
  68. Aug 2025
  69. www.sciencedirect.com www.sciencedirect.com
    Electrochemical coupling at the plasma membrane by mouse voltage-sensitive phosphatase requires association with basigin
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    sciencedirect.com/science/article/pii/S2211124725009714
  70. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70165
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70119
  72. Jul 2025
  73. www.sciencedirect.com www.sciencedirect.com
    Biology-aware machine learning for culture medium optimization
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    sciencedirect.com/science/article/pii/S1871678425000731
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression
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    Synaptic and intrinsic plasticity mediated by CCK-type signaling coordinates behavioral changes during motivational state shifts
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    sciencedirect.com/science/article/pii/S2211124725008204
  76. Jun 2025
  77. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70111
  78. 52.53.155.43 52.53.155.43
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    Structures of butyrophilin multimers reveal a plier-like mechanism for Vγ9Vδ2 T cell receptor activation
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    sciencedirect.com/science/article/pii/S1074761325002328
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural Insights into the High Basal Activity and Inverse Agonism of the Orphan GPR6 Receptor Implicated in Parkinson’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11850111/
  81. www.cell.com www.cell.com
    Biased agonism of GLP-1R and GIPR enhances glucose lowering and weight loss, with dual GLP-1R/GIPR biased agonism yielding greater efficacy
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    cell.com/cell-reports-medicine/abstract/S2666-3791(25)00229-0
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploiting Activated Alkyne Chemistry for the Synthesis of Tailored Amphiphilic Janus Dendrimers with Aggregation-Induced Emission and Their Assemblies for Cell Imaging
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133641/
  83. May 2025
  84. www.nature.com www.nature.com
    Cancer-associated loss-of-function mutations in KCNQ1 enhance Wnt/β-catenin signalling disrupting epithelial homeostasis
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    nature.com/articles/s41388-025-03447-4
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of a neutralization assay and bioluminescent imaging mouse model for Dehong virus (DEHV) using a pseudovirus system
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    pmc.ncbi.nlm.nih.gov/articles/PMC12054171/
  86. www.nature.com www.nature.com
    Electromagnetic wireless remote control of mammalian transgene expression
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    nature.com/articles/s41565-025-01929-w
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    Transfer of SARS-CoV-2 nucleocapsid protein to uninfected epithelial cells induces antibody-mediated complement deposition
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    sciencedirect.com/science/article/pii/S2211124725002839
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploiting Activated Alkyne Chemistry for the Synthesis of Tailored Amphiphilic Janus Dendrimers with Aggregation-Induced Emission and Their Assemblies for Cell Imaging
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  89. Apr 2025
  90. www.sciencedirect.com www.sciencedirect.com
    A blocking antibody against anti-Müllerian hormone restores ovulation and normal androgen levels in a spontaneous rat model of polycystic ovary syndrome
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    sciencedirect.com/science/article/pii/S2352396425001604
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    Synthetic deconvolution of an auxin-dependent transcriptional code
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    cell.com/cell/fulltext/S0092-8674(25)00346-0
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    Protocol to measure the impact of Clostridioides difficile toxins on antibody responses using ELISA, ELISPOT, and toxin-neutralization assays
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    sciencedirect.com/science/article/pii/S2666166725001601
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    Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets
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    sciencedirect.com/science/article/pii/S2451945625000959
  94. Mar 2025
  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Global characterization of mouse testis O-glycoproteome landscape during spermatogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11920050/
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    TMEM63B functions as a mammalian hyperosmolar sensor for thirst
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    sciencedirect.com/science/article/pii/S0896627325001308
  97. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  98. Feb 2025
  99. www.sciencedirect.com www.sciencedirect.com
    JNJ-78306358, a first-in-class bispecific T cell engaging antibody targeting CD3 and HLA-G
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    sciencedirect.com/science/article/pii/S2589004225001361
  100. aacrjournals.org aacrjournals.org
    ILT2 and ILT4 drive myeloid suppression via both overlapping and distinct mechanisms
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    aacrjournals.org/cancerimmunolres/article/12/5/592/745126/ILT2-and-ILT4-Drive-Myeloid-Suppression-via-Both
  101. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities
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