12 Matching Annotations
  1. May 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor-targeted IL-2 fusion protein
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067867/
  3. Mar 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-localized interleukin-2 and interleukin-12 combine with radiation therapy to safely potentiate regression of advanced malignant melanoma in pet dogs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11398984/
  5. Jan 2025
  6. 52.53.155.43 52.53.155.43
    Acidity-induced dysfunction of CD8+ T cells is characterized by impaired IL-2 responsiveness and perturbations to mTORC1 signaling and c-Myc levels
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    52.53.155.43/714b3a4b4f102fbda2f7d4eb1d71fcddef5e6e60/2023.12.15.571931v2.full-html.html
  7. Sep 2024
  8. www.sciencedirect.com www.sciencedirect.com
    A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
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    sciencedirect.com/science/article/pii/S2666379124004774
  9. May 2024
  10. www.sciencedirect.com www.sciencedirect.com
    CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity
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    sciencedirect.com/science/article/pii/S107476132400222X
  11. Oct 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Proteasome inhibition potentiates Kv1.3 potassium channel expression as therapeutic target in drug-sensitive and -resistant human melanoma cells
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    sciencedirect.com/science/article/pii/S0753332223014336
  13. Aug 2023
  14. www.nature.com www.nature.com
    Engineered E. coli Nissle 1917 for delivery of bioactive IL-2 for cancer immunotherapy
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    nature.com/articles/s41598-023-39365-2
  15. Jun 2023
  16. dx.doi.org dx.doi.org
    Collagen-anchored interleukin-2 and interleukin-12 safely reprogram the tumor microenvironment in canine soft tissue sarcomas
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    dx.doi.org/10.1158/1078-0432.CCR-23-0006
  17. Jul 2022
  18. www.sciencedirect.com www.sciencedirect.com
    Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING mediated T cell activation
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    sciencedirect.com/science/article/pii/S2589004222009622
  19. Jun 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity
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    sciencedirect.com/science/article/pii/S2666379122001926
  21. Sep 2020
  22. www.sciencedirect.com www.sciencedirect.com
    Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity
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    sciencedirect.com/science/article/pii/S2211124720310640
  23. Nov 2017
  24. www.cell.com www.cell.com
    Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob
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    cell.com/immunity/fulltext/S1074-7613(17)30320-5