Hypothesis

20 Matching Annotations

Jul 2026
www.biorxiv.org www.biorxiv.org

Prospective pan-cancer phosphoproteomics at clinical scale extends therapeutic options in precision oncology

1
1. scibot 14 Jul 2026
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.64898/2026.07.08.737171
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0270
  
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  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

biorxiv.org/content/10.64898/2026.07.08.737171v1
Apr 2026
aacrjournals.org aacrjournals.org

Anti-tumor activity of trastuzumab deruxtecan in pediatric solid tumors with variable HER2 expression

1
1. scibot 07 Apr 2026
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.1158/1535-7163.MCT-25-0437
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

aacrjournals.org/mct/article/25/1/156/771291/Antitumor-Activity-of-Trastuzumab-Deruxtecan-in
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Selective Alanine Transporter Utilization is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer

1
1. scibot 05 Aug 2025
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.1158/0008-5472.CAN-25-0654
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12314749/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs

1
1. scibot 29 Aug 2023
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.1158/2767-9764.CRC-23-0193
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0270
  
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  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10452929/
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Small-molecule allosteric inhibitors of GPX4

1
1. scibot 24 Nov 2022
  
  in Public
  
  CRL-1441
  
  DOI: 10.1016/j.chembiol.2022.11.003
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:CVCL_0270
  
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  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

sciencedirect.com/science/article/pii/S2451945622003877
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors

2
1. scibot 04 Oct 2022
  
  in Public
  
  CVCL_0270
  
  DOI: 10.1016/j.medj.2022.09.002
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270
2. scibot 04 Oct 2022
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.1016/j.medj.2022.09.002
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0270
  
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  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

sciencedirect.com/science/article/pii/S2666634022004032
May 2022
www.sciencedirect.com www.sciencedirect.com

NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition

1
1. scibot 12 May 2022
  
  in Public
  
  CVCL_0270
  
  DOI: 10.1016/j.molcel.2022.04.015
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

sciencedirect.com/science/article/pii/S1097276522003264
Mar 2022
www.nature.com www.nature.com

Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors

1
1. scibot 26 Mar 2022
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.1038/s41467-022-29152-4
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

nature.com/articles/s41467-022-29152-4
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.1016/j.celrep.2019.07.021
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_0270
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RRID:CVCL_0270

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719309118
Jul 2021
www.sciencedirect.com www.sciencedirect.com

EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex

1
1. scibot 31 Jul 2021
  
  in Public
  
  G401
  
  DOI: 10.1016/j.chembiol.2019.11.004
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270 RRIDCUR:Missing
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RRID:CVCL_0270

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2451945619303629
www.sciencedirect.com www.sciencedirect.com

Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

1
1. scibot 31 Jul 2021
  
  in Public
  
  G-401
  
  DOI: 10.1016/j.celrep.2019.10.083
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270 RRIDCUR:Missing
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RRID:CVCL_0270

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719314056
www.sciencedirect.com www.sciencedirect.com

ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures

1
1. scibot 31 Jul 2021
  
  in Public
  
  Human: G401
  
  DOI: 10.1016/j.ccell.2019.09.002
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270 RRIDCUR:Missing
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RRID:CVCL_0270

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S153561081930385X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID: CVCL_0270
  
  DOI: 10.1016/j.cell.2019.10.044
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC7175411/
Apr 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

1
1. scibot 24 Apr 2021
  
  in Public
  
  CRL-1441
  
  DOI: 10.1016/j.cell.2020.12.025
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270 RRIDCUR:Missing
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RRID:CVCL_0270

RRIDCUR:Missing

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC7886018/
Sep 2020
elifesciences.org elifesciences.org

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.7554/eLife.44161
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_0270
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RRID:CVCL_0270

RRIDCUR:Validated

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scibot

URL

elifesciences.org/articles/44161
www.sciencedirect.com www.sciencedirect.com

Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID: CVCL_0270
  
  DOI: 10.1016/j.ccell.2020.04.002
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270
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RRID:CVCL_0270

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820301641
Jan 2020
www.sciencedirect.com www.sciencedirect.com

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270 RRIDCUR:Validated
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RRID:CVCL_0270

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819300406
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0270
  
  DOI: 10.7554/eLife.44161
  
  Resource: (JCRB Cat# JCRB9065, RRID:CVCL_0270)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0270
  
  What is this?
  
  RRID:CVCL_0270 RRIDCUR:Validated
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RRID:CVCL_0270

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6436895/
Nov 2017
www.sciencedirect.com www.sciencedirect.com

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

1
1. scibot 08 Nov 2017
  
  in Public
  
  G401ATCCCat#CRL-1441
  
  Curator: @Jmenke
  
  Resource used:
  
  (ECACC Cat# 87042204, RRID:CVCL_0270)
  
  SciCrunch record: RRID:CVCL_0270
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0270 RRIDCUR:Missing
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RRID:CVCL_0270

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276517304069