139 Matching Annotations
  1. Last 7 days
  2. elifesciences.org elifesciences.org
    CROP2, a Retriever–PROPPIN complex mediating protein export from endosomes to the plasma membrane in human cells
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    elifesciences.org/articles/109403
  3. 54.241.53.176 54.241.53.176
    pompeu-et-al-2026-copper-dependent-redox-remodeling-of-the-actin-cytoskeleton-regulates-renal-epithelial-cell-mechanics-html.html
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  4. Jul 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptomics reveal dysregulated genes during folic acid-induced acute injury and fibrosis in kidney and their attenuation by antioxidant N-acetyl cysteine
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    pmc.ncbi.nlm.nih.gov/articles/PMC13383868/
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Diagnostic potential of B-cell translocation gene 2 in IgA nephropathy: Insights from molecular mechanisms
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    onlinelibrary.wiley.com/doi/10.1002/ccs3.70082
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    A kidney-protective mechanism via cellular oxidative stress reduction induced by CD5L protein
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    54.241.53.176/66241ed78d9b18421f2ce8f45068c67eeaf4d267/s41420-026-03171-2_reference-html.html
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    VHL-recruiting PROTAC attenuates AKI-CKD transition via simultaneous degradation of Smad3 and stabilization of HIF-2α
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    nature.com/articles/s41419-026-08726-w
  9. Jun 2026
  10. www.sciencedirect.com www.sciencedirect.com
    Tubular basement membrane damage promotes renal fibrosis via an ETV5/TGFB1/SOX9 axis in proximal tubular epithelial cells after acute kidney injury
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    sciencedirect.com/science/article/pii/S0898656826003396
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    ENPP1 blockade with a humanized monoclonal antibody enhances renal repair after acute kidney injury
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    sciencedirect.com/science/article/pii/S1934590926002031
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    iMSC-secreted factors preserve renal capillary networks and ameliorate fibrosis by interrupting the macrophage STING/CD8+ T cell axis in ischemic kidney disease
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    link.springer.com/article/10.1186/s13287-026-05099-x
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Qingxin Lianzi Yin Improves Chronic Kidney Disease by Targeting Ferroptosis via the TLR4/HIF‐1α Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13238268/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing platinum-based chemotherapy efficacy and safety through combination therapy-mediated remodeling of autophagic homeostasis in gastric cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13234414/
  15. May 2026
  16. link.springer.com link.springer.com
    The LINC00920/miR-6834-3p/CPN1 Axis Modulates Immune Dysregulation in Sepsis-Associated Acute Kidney Injury and Serves as a Diagnostic Biomarker
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    link.springer.com/article/10.1007/s10528-026-11393-3
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    OSCAR functions as a collagen I receptor to suppress hippo signaling and reprogram lipid metabolism in clear-cell renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13187165/
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cross-Cohort Transcriptomic Integration Identifies IFIT2 as a Translational Diagnostic Biomarker and Functional Driver of Inflammation-Linked Tubular Injury in Chronic Kidney Disease
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    onlinelibrary.wiley.com/doi/10.1155/humu/8282277
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    Integrating Bulk and Single-Cell RNA-Seq Reveals Glycolysis-Associated Macrophages and Its Related Tumor Subgroup Signatures to Predict Prognosis and Therapy in Clear Cell Renal Cell Carcinoma
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    onlinelibrary.wiley.com/doi/10.1155/humu/3125551
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    NDUFA5 deficiency promotes renal inflammation in diabetic nephropathy via mitochondrial ROS signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13138032/
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    Curcumin regulates ferroptosis by activating α7 nicotinic acetylcholine receptor to improve sepsis-induced acute kidney injury
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    tandfonline.com/doi/abs/10.1080/0886022X.2026.2657652
  22. Apr 2026
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    USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2211124726004067
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    Curcumin regulates ferroptosis by activating α7 nicotinic acetylcholine receptor to improve sepsis-induced acute kidney injury
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    tandfonline.com/doi/abs/10.1080/0886022X.2026.2657652
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    Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70500
  28. Mar 2026
  29. www.sciencedirect.com www.sciencedirect.com
    A novel MST1-targeting kinsenoside derivative K30 attenuates acute kidney injury by restoring mitochondrial homeostasis
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    sciencedirect.com/science/article/pii/S2211383526001590
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra-Targeted Tumor α-Therapy
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    onlinelibrary.wiley.com/doi/full/10.1002/exp2.70144
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    Imidazole Propionate Induces Kidney Damage by Activating the ROS‐NLRP3 Signaling Pathway Through mTOR Inhibition of Autophagy in Renal Tubular Epithelial Cells
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  34. Feb 2026
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vericiguat attenuates cyclosporine A-induced nephropathy by targeting the NF-κB/TGF-β1 axis: an integrated network pharmacology, Mendelian randomization, and experimental study
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    Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer
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  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZNF395 is a Hypoxia-Responsive Regulator of Mitochondrial Glutaminolysis in Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12875648/
  38. Jan 2026
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Empty spiracles homeobox 2 (EMX2) transcription factor functions as a tumor suppressor in renal cell carcinoma by targeting CADM1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12807814/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Senloytics, dasatinib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease
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  41. Dec 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TFE3 fusion proteins promoted the progression of Xp11.2 translocation renal cell carcinoma through post-translational modification of PDL1 by upregulating CCND1/Cyclin D1
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    tRF-21LeuTAA Promotes Oxidative Stress by Altering Glutathione Metabolic Enzymes to Support Prostate Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666318/
  45. Nov 2025
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    Epigallocatechin Gallate Attenuates CaOx Crystal-Induced Renal Tubular Injury to Inhibit CaOx Nephrolithiasis via GRP94/PI3K/AKT Signaling
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    Tryptophan-Conjugated Carbon Dots with Enhanced Cellular Uptake as a Potential Drug Delivery System for Melanoma
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    pubs.acs.org/doi/10.1021/acsabm.5c01730
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    Affinity-Based Protein Profiling Revealed that HIGD1A is a Direct Target Protein of Aristolochic Acids
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513117
  49. Oct 2025
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    TCIRG1 as a Novel Prognostic Biomarker Triggering Immune Infiltration in Renal Clear Cell Carcinoma: An Integrative Study of Single-Cell and Bulk Data
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    Activation of TLR4-NF-κB signaling in renal tubular epithelial cells facilitates renal allograft fibrosis by inhibiting peroxisome biogenesis
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    sciencedirect.com/science/article/pii/S0925443925004144
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    Role of SAA1 in mediating renal fibrosis through TLR4-dependent NF-κB activation
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    link.springer.com/article/10.1186/s12882-025-04438-z
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated single-cell and bulk transcriptome analysis revealed high plasticity subpopulation and promising diagnosis model for clear cell renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12487111/
  55. Sep 2025
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overexpression of PON1 reduces high glucose induced renal tubular epithelial cell injury by activating PPARγ signaling pathway to alleviate diabetes nephropathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12377028/
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    Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma
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  58. Aug 2025
  59. www.tandfonline.com www.tandfonline.com
    Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma
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    tandfonline.com/doi/full/10.1080/07853890.2025.2548042
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    Design of multi-target peptide modulators for protein chaperone networks
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    The natural compound stachyose targets SGLT2-mediated metabolic reprogramming to ameliorate diabetic kidney disease
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    sciencedirect.com/science/article/pii/S0944711325008219
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    Novel Coumarin Derivative SZC-6 as an Allosteric Activator of SIRT3 Alleviates Diabetic Kidney Disease via the SIRT3-Foxo3a Signaling Axis
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    TRIM65 as a key regulator of ferroptosis and glycolysis in lactate-driven renal tubular injury and diabetic kidney disease
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    sciencedirect.com/science/article/pii/S2211124725008629
  64. Jun 2025
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    Syndecan-1-mediated loading of VEGF-A into small extracellular vesicles facilitates peritubular capillary repair during AKI-to-CKD transition
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  66. www.nature.com www.nature.com
    PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma
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    nature.com/articles/s41419-025-07782-y
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
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    Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
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    tandfonline.com/doi/abs/10.2147/DDDT.S515409
  69. May 2025
  70. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Augmenter of liver regeneration (ALR) can regulate iron homeostasis through the INOS/NO/SLC39A14 pathway to reduce ferroptosis in acute kidney injury
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  71. Apr 2025
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11951319/
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    Glabridin ameliorates hemorrhagic shock induced acute kidney injury by activating Nrf2/HO-1 pathway
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  74. Mar 2025
  75. 52.53.155.43 52.53.155.43
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    Receptor-associated protein impairs ligand binding to megalin and megalin-dependent endocytic flux in proximal tubule cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11905868/
  77. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Static magnetic fields alleviate diabetic nephropathy by reducing renal cell inflammation and promoting M2 macrophage polarization
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202500061R
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    Both carvedilol and cimetidine alleviate cisplatin-induced nephrotoxicity via downregulating OCT2
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  79. Jan 2025
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11772299/
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  82. Dec 2024
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    Tumor necrosis factor-stimulated gene-6 inhibits endoplasmic reticulum stress in the ischemic mouse kidney
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    Structure-guided development of selective caseinolytic protease P agonists as antistaphylococcal agents
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  85. Oct 2024
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    S100A9 promotes renal calcium oxalate stone formation via activating the TLR4-p38/MAPK-LCN2 signaling pathway
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    sciencedirect.com/science/article/pii/S0141813024069873
  87. Sep 2024
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    Epigenetic alterations in bioaccumulators of cadmium: Lessons from mammalian kidneys and plants
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  89. Aug 2024
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX11 as a prognostic biomarker linked to m6A modification and immune infiltration in renal clear cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11319951/
  91. elifesciences.org elifesciences.org
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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    elifesciences.org/content/5/e17047
  92. Jul 2024
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage migration inhibitory factor (MIF) suppresses mitophagy through disturbing the protein interaction of PINK1-Parkin in sepsis-associated acute kidney injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC11220046/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Renal inflammation combined with renal function reserve reduction accelerate kidney aging via pentose phosphate pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11214290/
  95. May 2024
  96. www.sciencedirect.com www.sciencedirect.com
    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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    sciencedirect.com/science/article/pii/S235239642400197X
  97. aacrjournals.org aacrjournals.org
    Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
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    aacrjournals.org/cancerres/article/84/10/1570/745316/Bile-Acid-Metabolism-Mediates-Cholesterol
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    Megalin-targeted acetylcysteine polymeric prodrug ameliorates ischemia-reperfusion-induced acute kidney injury
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    sciencedirect.com/science/article/pii/S2405844024069780
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  100. Apr 2024
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    Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling
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  102. Feb 2024
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating HMGB1 as a Potential Serum Biomarker for Early Diabetic Nephropathy Monitoring by Quantitative Proteomics
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830865/
  104. Dec 2023
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion
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