150 Matching Annotations
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    SARS-CoV-2 ORF7a induces cytotoxicity associated with AP-1 signaling and ferroptosis-related responses
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    FTO mediated glycolytic metabolism for papillary renal cell carcinoma immune evasion
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    Sirt3 attenuates LPS-induced mitochondrial fission in renal tubular epithelial cells through the AMPK-Drp1 pathway
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    Zyxin protects against hypertensive nephropathy by restraining FAK/Skp2–CDK8/YAP signaling in tubular epithelial cells
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    FOXM1-mediated transcriptional activation of CILP2 promotes malignant phenotypes and EMT-associated remodeling in clear cell renal cell carcinoma
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    Gut Microbiota-Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1-Mediated Parthanatos
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    Targeted Degradation of ATP7B via a Novel Autophagy-Targeting Chimera Promotes Cuproptosis to Potentiate Anti-Tumor Immunity in Clear Cell Renal Cell Carcinoma
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    Chelerythrine and Chelidonine Synergistically Target the Adenosine Pathway to Improve Anti-PD-L1 Immunotherapy Efficacy in Lung Cancer
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  15. Jul 2026
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    CROP2, a Retriever–PROPPIN complex mediating protein export from endosomes to the plasma membrane in human cells
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    Transcriptomics reveal dysregulated genes during folic acid-induced acute injury and fibrosis in kidney and their attenuation by antioxidant N-acetyl cysteine
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    VHL-recruiting PROTAC attenuates AKI-CKD transition via simultaneous degradation of Smad3 and stabilization of HIF-2α
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  22. Jun 2026
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    Tubular basement membrane damage promotes renal fibrosis via an ETV5/TGFB1/SOX9 axis in proximal tubular epithelial cells after acute kidney injury
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    iMSC-secreted factors preserve renal capillary networks and ameliorate fibrosis by interrupting the macrophage STING/CD8+ T cell axis in ischemic kidney disease
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    Qingxin Lianzi Yin Improves Chronic Kidney Disease by Targeting Ferroptosis via the TLR4/HIF‐1α Pathway
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  28. May 2026
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    The LINC00920/miR-6834-3p/CPN1 Axis Modulates Immune Dysregulation in Sepsis-Associated Acute Kidney Injury and Serves as a Diagnostic Biomarker
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    OSCAR functions as a collagen I receptor to suppress hippo signaling and reprogram lipid metabolism in clear-cell renal cell carcinoma
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  35. Apr 2026
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    USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma
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    A novel MST1-targeting kinsenoside derivative K30 attenuates acute kidney injury by restoring mitochondrial homeostasis
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  51. Jan 2026
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  54. Dec 2025
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  58. Nov 2025
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  68. Sep 2025
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    The natural compound stachyose targets SGLT2-mediated metabolic reprogramming to ameliorate diabetic kidney disease
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    Novel Coumarin Derivative SZC-6 as an Allosteric Activator of SIRT3 Alleviates Diabetic Kidney Disease via the SIRT3-Foxo3a Signaling Axis
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    TRIM65 as a key regulator of ferroptosis and glycolysis in lactate-driven renal tubular injury and diabetic kidney disease
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  77. Jun 2025
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    Syndecan-1-mediated loading of VEGF-A into small extracellular vesicles facilitates peritubular capillary repair during AKI-to-CKD transition
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    PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma
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    Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
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    Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
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  82. May 2025
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    Augmenter of liver regeneration (ALR) can regulate iron homeostasis through the INOS/NO/SLC39A14 pathway to reduce ferroptosis in acute kidney injury
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  84. Apr 2025
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    Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress
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    Glabridin ameliorates hemorrhagic shock induced acute kidney injury by activating Nrf2/HO-1 pathway
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  87. Mar 2025
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    Receptor-associated protein impairs ligand binding to megalin and megalin-dependent endocytic flux in proximal tubule cells
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    Static magnetic fields alleviate diabetic nephropathy by reducing renal cell inflammation and promoting M2 macrophage polarization
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    Both carvedilol and cimetidine alleviate cisplatin-induced nephrotoxicity via downregulating OCT2
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  92. Jan 2025
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    Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease
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  95. Dec 2024
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    Tumor necrosis factor-stimulated gene-6 inhibits endoplasmic reticulum stress in the ischemic mouse kidney
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  98. Oct 2024
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    S100A9 promotes renal calcium oxalate stone formation via activating the TLR4-p38/MAPK-LCN2 signaling pathway
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  100. Sep 2024
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    Epigenetic alterations in bioaccumulators of cadmium: Lessons from mammalian kidneys and plants
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