394 Matching Annotations
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    Colorectal cancer cell-derived exosomes induce metabolic reprogramming of cancer-associated fibroblasts to promote colorectal cancer growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12644288/
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    The diagnostic value of miR-340-5p in pediatric ulcerative colitis and its molecular mechanism by targeting MAP3K2 to modulate intestinal epithelial cell dysfunction
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    link.springer.com/article/10.1186/s41065-025-00597-z
  4. Nov 2025
  5. www.sciencedirect.com www.sciencedirect.com
    Coastal halophyte plant Atriplex maximowicziana with previously undescribed terpenoids and anti-colorectal cancer chlorophyll stereoisomers utilizing a molecular networking approach
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    sciencedirect.com/org/science/article/pii/S2046206925034059
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    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    sciencedirect.com/science/article/pii/S2211383525007452
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    Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells
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    sciencedirect.com/science/article/pii/S2666379125005191
  8. 54.241.53.176 54.241.53.176
    2025.11.06.687028v2.full-html.html
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    CDC7 stabilized by KRAS signaling reactivation impairs chemosensitivity in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S1043661825004529
  10. elifesciences.org elifesciences.org
    The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation
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    elifesciences.org/reviewed-preprints/102714
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    Cytoplasmic HMGB1 promotes and interacts with BECN1 through ZNF460 to induce autophagy and accelerate radioresistance in colorectal cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12558843/
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    SUNRISE-CRC: a randomized phase II study of high-dose intermittent sunitinib versus trifluridine/tipiracil in metastatic colorectal carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12573252/
  13. Oct 2025
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    Purinergic Ecto-Enzyme CD73 is a Context-Dependent Tumor Suppressor in Colorectal Cancer
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    sciencedirect.com/science/article/pii/S0021925825027164
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    Hotspot mutant p53-R273H enhances mitochondrial biogenesis and cell migration in primary colorectal cancer in response to oxaliplatin
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    sciencedirect.com/science/article/pii/S0167488925001788
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    Development of the FGFR4-ADC bearing the ferroptosis inducer sulfasalazine for hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004225019790
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    Phase separation of circCHD6-encoded 216aa protein promotes colorectal cancer metastasis
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    CPT1A facilitated ferroptosis by forming feedback loop with Nrf2 via PI3K/AKT pathway in colorectal cancer
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  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MM-129 Counteracts 5-Fluorouracil-Induced Cellular Senescence in Colon Cancer via SIRT1/STAT3 Signaling Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12524155/
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    A synthetic benzoxazine dimer derivative targets c-Myc to inhibit colorectal cancer progression
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    Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy
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    Synergistic anticancer effects of ABT-199 and Vorinostat encapsulated in PLGA nanoparticles: Formulation, characterization, and antiproliferative effects against colorectal cancer cells
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    Limited activation interdependence and differing patterns of the in vivo effects of IKK1 and IKK2 downstream of NIK
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  25. Sep 2025
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    Self-Propelled Magnetic Micromotor-Functionalized DNA Tile System for Autonomous Capture of Circulating Tumor Cells in Clinical Diagnostics
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    c-Met inhibitor NVP-BVU972 induces antiviral protection and suppresses NF-κB-mediated inflammation
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    Chemotherapy modulation by a cancer-associated microbiota metabolite
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    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer
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    HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
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  33. Aug 2025
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    TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation
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    The exopolysaccharides from Streptococcus mutans ATCC 35668 for inhibiting the growth of HT-29 colorectal cancer cell line
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    Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression
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    Pharmacodynamic analyses of LAT1 inhibitors in vitro and in vivo by targeted metabolomics reveal target-independent effects
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  45. Jul 2025
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    Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early-Onset Colorectal Cancer
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    The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis
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    Substitution of a proline residue in the frog skin host-defense peptide, figainin-2PL by D-lysine generates an analog with potent activity against antibiotic-resistant ESKAPE pathogens
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    Separation-of-function mutants reveal the NF-κB-independent involvement of IκBα in the regulation of intestinal stemness
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    Neuro-mesenchymal interaction mediated by a β2 adrenergic-nerve growth factor feedforward loop promotes colorectal cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11729495/
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    2D and 3D in vitro photodynamic activities of tetra-substituted symmetric water-soluble cationic zinc(II) phthalocyanines on cancer
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    Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression
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    Identification of UBE3C as an E3 ubiquitin ligase for mutant BRAF
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    Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates
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    Filamin A C-terminal fragment modulates Orai1 expression by inhibition of protein degradation | American Journal of Physiology-Cell Physiology | American Physiological Society
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  60. Jun 2025
  61. www.cell.com www.cell.com
    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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    RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation
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    Itaconate and obesity-related hormones promote tumor progression – new insights on metabolic dysfunction in early-onset colon cancer
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    Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
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    Epithelial Regnase-1 inhibits colorectal tumor growth by regulating IL-17 signaling via degradation of <i>NFKBIZ</i> mRNA
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    Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome
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    Flagellar switch inverted repeats impact heterogeneity in flagellar gene expression and thus C. difficile RT027/MLST1 virulence
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    TR-107, An Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells
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    Anti-Inflammatory Effect and Gut Health of Levilactobacillus brevis Strains in Macrophage and Intestinal Cells
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    Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin
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  72. May 2025
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    Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway
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    Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity
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    Metformin reverses 5-FU resistance induced by radiotherapy through mediating folate metabolism in colorectal cancer
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    Novel Approaches to 3D Cancer Heterospheroid Culture and Assay Development for Immunotherapy Screening
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    Integrative proteomic profiling of tumor and plasma extracellular vesicles identifies a diagnostic biomarker panel for colorectal cancer
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    Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors
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  79. Apr 2025
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    ZBP1 senses splicing aberration through Z-RNA to promote cell death
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    Initial gut microbiota composition is a determining factor in the promotion of colorectal cancer by oral iron supplementation: evidence from a murine model
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    ARID3A inhibits colorectal cancer cell stemness and drug-resistance by targeting a multitude of stemness-associated genes
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    A new EGFR and c-Met bispecific NIR-II fluorescent probe for visualising colorectal cancer and metastatic lymph nodes
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    Streptomycin targets tumor-initiating cells by disrupting oxidative phosphorylation
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    N6-methyladenosine in DNA promotes genome stability
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    The imidazoline I2 receptor agonist 2-BFI enhances cytotoxic activity of hydroxychloroquine by modulating oxidative stress , energy-related metabolism and autophagic influx in human colorectal adenocarcinoma cell lines
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    VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity
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    Augmenting CAR T Cell Functions with LIGHT
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  89. Mar 2025
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