456 Matching Annotations
  1. Last 7 days
  2. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Synergistic Anticancer Effects of Akkermansia muciniphila Combined With 5-Fluorouracil Through BAX/BCL2 Dependent Apoptosis in Colorectal Cancer Cells
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/cbf.70234
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    iRGD-functionalized PLGA nanocomplex co-loaded with paclitaxel and Trametes robiniophila Murr for targeted inhibition of chemoresistant and metastatic signaling gene PDCD4 in colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13173983/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Betrixaban activates cGAS and ERVs to promote dual nucleic-sensing antiviral immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13179341/
  5. May 2026
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    ISG15 negatively regulates RIPK3-mediated cell death and viral pathogenesis
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    sciencedirect.com/science/article/pii/S2211124726004389
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    Metabolic stress conditions dictate MAPKAPK2-dependent efficiency of MEK1/2 inhibition in colorectal carcinoma
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    pnas.org/doi/10.1073/pnas.2505331123
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFITM1-targeted NIR-II fluorescence imaging enables visualisation of colorectal cancer and metastatic lymph nodes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13134288/
  9. Apr 2026
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    The cytotoxic effect of prexasertib is a consequence of dual inhibition on both CHK1 and AMPK
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    sciencedirect.com/science/article/pii/S2451945626001121
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxic CAF studies unveil PTHrP-vitamin D-RAS axis as pivotal in the CAF
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    pmc.ncbi.nlm.nih.gov/articles/PMC13107517/
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    Protocol to identify covalent inhibitors targeting RhoA Cys16
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    pmc.ncbi.nlm.nih.gov/articles/PMC13092739/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ASCL2 drives colorectal cancer metastasis through transcriptional activation of TDGF1
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  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phenolic Profiles and Cytotoxic Activities of Methanolic Extracts From Eight Geranium L. Species
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503814
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    Synthesis and characterization of NIR-sensitive curcumin-gelatin nanoparticles for targeted drug delivery in 3D colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13076676/
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    Mosperafenib, a novel paradox breaker BRAF inhibitor with potent preclinical activity in BRAF mutated colorectal cancer
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    aacrjournals.org/mct/article/25/4/599/776467/Mosperafenib-a-Novel-Paradox-Breaker-BRAF
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    Integrative Multiomics and Single‐Cell Analyses Identify FKBP10 as a Predictor of Radiotherapy Outcome in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13062661/
  18. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Structure-Guided Synthetic Peptide Targeting Nucleolus and Neural Progenitor Protein Nuclear Import Impairs Ribosome Biogenesis and Cancer Cell Proliferation
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202500799
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    Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer
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    IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
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    sciencedirect.com/science/article/pii/S2451945626000759
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    EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS-STING Pathway
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202522826
  22. Mar 2026
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    Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature
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    HMGB1 reduce DNA damage by binding KU70 to activate NHEJ pathway in colorectal cancer cells after radiation
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    CGF induces ROS-mediated metabolic reprogramming and mitochondrial dysfunction to suppress colorectal cancer progression
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    Autoinhibitory control of MLKL governs pseudokinase domain phosphorylation and oligomerization during necroptosis
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    A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancer
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    Pooled single-cell screen in colorectal cancer defines transcriptional modules linked to oncogenes
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    Nigakinone enhances FXR expression to synergize with irinotecan in suppressing colorectal cancer cells and xenografts
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    Lysine-11 ubiquitination drives type-I/III interferon induction by cGAS–STING and Toll-like receptors 3 and 4
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    Pentatropis capensis-Derived Phyto-Compounds: In Silico Analysis Targeting of DCAF1/VprBP in Colorectal Cancer and Biochemical Studies
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  33. Feb 2026
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    Global mapping of circRNA-target RNA interactions reveal P-body-mediated translational repression
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    A comprehensive review of anti-colorectal cancer alkaloids from traditional Chinese medicine: Sources, chemical structures, mechanisms and therapeutic applications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70343
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    Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling
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    Compartmentalized branched-chain amino acid metabolism orchestrates colorectal cancer dissemination via an UMP-vimentin axis
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    Colorectal cancer-derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver
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    Fibroblast-derived POSTN promotes colorectal cancer progression under high-fat diet by reprogramming fatty acid metabolism in tumor cell
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    Multi-Target Anticancer Activity of Justicia betonica L.: Phytochemical Profiling, In Silico Screening, and Preclinical Evaluation
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    Deep Learning-Powered Scalable Cancer Organ Chip for Cancer Precision Medicine
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    Gut microbiota-derived isovaleric acid alleviates atrial fibrillation by suppressing GSDME-dependent pyroptosis
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    Epithelial Gab1 Restricts Sepsis‐Induced Intestinal Injury by Orchestrating TNF/NF‐κB Axis
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  45. Jan 2026
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    Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy
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    Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
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    Revealing the Action Mechanism of Exogenous Hydrogen Sulfide Intervention in Colorectal Cancer Pathogenesis Based on Multiomics Analysis and Experimental Validation
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    Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target
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    New applications of sustainable, scalable, standardized, and cost-effective human biomaterials for cell-based assays, tissue engineering, and regenerative medicine
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    Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis
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    The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression
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    Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment
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    CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance
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    Lactobacillus delbrueckii surface protein P4430 attenuates intestinal inflammation by modulating macrophage polarization via Mincle
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    USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer
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    KRASG12/13 mutation modulates CRC outcomes via disrupting positive feedback between macrophage and CD4+ T cell
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    Long non-coding RNA UCA1 modulates SMARCA2-containing SWI/SNF chromatin remodeling complexes in human colorectal cancer
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  62. Dec 2025
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    A TRIM21–UCHL3–ITCH–SIPA1 axis promotes colorectal cancer growth and metastasis
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    In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation, and exacerbation of inflammation
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    A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression
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    Exploiting the Biogenic Potential of Spirulina platensis for the Sustainable Synthesis of Multifunctional and Bioactive Magnesium Oxide Nanoparticles
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    Design, synthesis, and structural elucidation of ethyl 2-amino-5-oxo-4-aryl-4 H -pyrano[3,2- c ]quinoline-3-carboxylates as dual EGFR/HER-2 inhibitors endowed with antiproliferative activity
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    Sustained reductions in valine and isoleucine mediate anti-cancer pharmacological effects of inhibiting amino acid transporter LAT1 in cancer cells
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  69. Nov 2025
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    Colorectal cancer cell-derived exosomes induce metabolic reprogramming of cancer-associated fibroblasts to promote colorectal cancer growth
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    The diagnostic value of miR-340-5p in pediatric ulcerative colitis and its molecular mechanism by targeting MAP3K2 to modulate intestinal epithelial cell dysfunction
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    Coastal halophyte plant Atriplex maximowicziana with previously undescribed terpenoids and anti-colorectal cancer chlorophyll stereoisomers utilizing a molecular networking approach
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    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells
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    CDC7 stabilized by KRAS signaling reactivation impairs chemosensitivity in KRAS-mutant colorectal cancer
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  77. elifesciences.org elifesciences.org
    The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation
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    Cytoplasmic HMGB1 promotes and interacts with BECN1 through ZNF460 to induce autophagy and accelerate radioresistance in colorectal cancer cells
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  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SUNRISE-CRC: a randomized phase II study of high-dose intermittent sunitinib versus trifluridine/tipiracil in metastatic colorectal carcinoma
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  80. Oct 2025
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    Purinergic Ecto-Enzyme CD73 is a Context-Dependent Tumor Suppressor in Colorectal Cancer
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    Hotspot mutant p53-R273H enhances mitochondrial biogenesis and cell migration in primary colorectal cancer in response to oxaliplatin
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    Development of the FGFR4-ADC bearing the ferroptosis inducer sulfasalazine for hepatocellular carcinoma
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    Phase separation of circCHD6-encoded 216aa protein promotes colorectal cancer metastasis
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    CPT1A facilitated ferroptosis by forming feedback loop with Nrf2 via PI3K/AKT pathway in colorectal cancer
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    link.springer.com/article/10.1007/s10495-025-02171-4
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MM-129 Counteracts 5-Fluorouracil-Induced Cellular Senescence in Colon Cancer via SIRT1/STAT3 Signaling Pathway
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    A synthetic benzoxazine dimer derivative targets c-Myc to inhibit colorectal cancer progression
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    Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy
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    Synergistic anticancer effects of ABT-199 and Vorinostat encapsulated in PLGA nanoparticles: Formulation, characterization, and antiproliferative effects against colorectal cancer cells
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  188. Nov 2024
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  194. Oct 2024
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