104 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRPV4 is involved in NLRP3 and NLRP1 inflammasomes activation after pilocarpine-induced status epilepticus in mice: Concise title: TRPV4-mediated inflammasome activation in epilepsy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13187113/
  3. Apr 2026
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    Fluoxetine Alleviates Vascular Cognitive Impairment by Activating the Nrf2/ARE Pathway via Sp1-Mediated OTUD1 Transcription
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    tandfonline.com/doi/abs/10.1080/10715762.2026.2658796
  5. pubs.acs.org pubs.acs.org
    An Interpretable, Thermodynamics-Based Deep Learning Framework for Predicting and Optimizing Drug Membrane Permeability
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    pubs.acs.org/doi/full/10.1021/acs.jmedchem.6c00204
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    SARS-CoV-2 directly infects the inner ear and causes hearing dysfunction
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    sciencedirect.com/science/article/pii/S2211124726003293
  7. Mar 2026
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    Destabilized Soluble SOD1 Species as Potential Determinants of Disease Severity in Familial Amyotrophic Lateral Sclerosis
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    pubs.acs.org/doi/full/10.1021/acschemneuro.5c00668
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    Nrf2 maintains reactive oxygen species at an optimal level during endoplasmic reticulum stress in HT22 cells
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    sciencedirect.com/science/article/pii/S0171933526000075
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    Multi-component functionalized Bifidobacterium longum hydrogel for multi-target integrated therapy of colitis-associated anxiety and depression
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    biorxiv.org/content/10.64898/2026.03.10.710940v1
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    Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70402
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    FAT4 loss promotes tumor growth and ferroptosis resistance in hepatocellular carcinoma via PI3K/AKT pathway activation
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    link.springer.com/article/10.1007/s12094-026-04302-y
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    The landscape of gene mutations in a cohort of 3353 Han Chinese children with nonsyndromic hearing loss
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    sciencedirect.com/science/article/pii/S2352396426000939
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    Nature-Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518969
  15. Feb 2026
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anesthetic gas sevoflurane postconditioning alleviates cognitive impairment induced by hemorrhagic shock and resuscitation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12935133/
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    Targeting AARS1-dependent lactylation improves neuronal process plasticity and mitigates cognitive deficits in sepsis-associated encephalopathy
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    sciencedirect.com/science/article/pii/S0889159126002412
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inflammatory Factors Derived From Metabolic Dysfunction‐Alcoholic Fatty Liver Disease: Inducers of Anxiety and Spatial Memory Impairment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12887228/
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    Lumbrokinase modulates tissue plasminogen activator and alleviates behavioral and cognitive deficits in mice with chronic social defeat stress
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    sciencedirect.com/science/article/pii/S0753332226000569
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    Neuron-glioma synaptic transmission amplified by free 19S proteasome-mediated AMPAR deubiquitination promotes tumor progression
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    sciencedirect.com/science/article/pii/S1878747926000176
  21. Jan 2026
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    Co-treatment Strategy Supports Neuroprotection by Intersecting p62-Keap1-NRF2 and Autophagy Signaling Pathways in the Cellular Model of Parkinson's Disease
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    link.springer.com/article/10.1007/s10571-025-01610-9
  23. Dec 2025
  24. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress-Induced Depression in Male Mice
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513438
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    Modest improvement of metabolic and behavioral deficits with long-term ambroxol treatment in a Pink1−/−SNCAA53T double mutant mouse model of Parkinson’s disease
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    nature.com/articles/s41401-025-01690-9
  26. Nov 2025
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    BDNF exerts an NRF2-dependent cytoprotective function via a receptor-independent pathway
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    sciencedirect.com/science/article/pii/S2211124725013592
  28. Oct 2025
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    Optimized Single-Shank Silicon Neural Probe for Neural Recording in Non-Human Primates
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    advanced.onlinelibrary.wiley.com/doi/10.1002/admt.202501356
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    Unveiling the Therapeutic Potential of D2AAK1 and Its Derivatives: Mechanistic Insights and Applications in Neurodegenerative Disease Treatment
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70232
  31. Sep 2025
  32. www.sciencedirect.com www.sciencedirect.com
    ANXA2 knockdown inhibits oxidative stress and pyroptosis to alleviate epilepsy by suppressing the toll-like receptor (TLR) pathway
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    Elevated hexosylceramides in Parkinson’s disease cause gene upregulations in neurons mimicking responses to pathogens
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    nature.com/articles/s41531-025-01114-9
  34. Aug 2025
  35. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Neurophilic Biomimetic Lipoprotein-Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202509405
  36. Jul 2025
  37. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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  38. Jun 2025
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    Inhibition of phosphodiesterase-4 by rolipram alleviates anxiety-like behavior in mice with PTSD by modulating neuroinflammation and synaptic plasticity via cAMP signaling
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  41. May 2025
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    Bromodomain-containing protein 4 knockdown promotes... : Neural Regeneration Research
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    Prostaglandin endoperoxide synthase 2 regulates neuroinflammation to mediate postoperative cognitive dysfunction in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089394/
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    Therapeutic time window of Sodium of Danshensu on cerebral ischemia and its mechanism of inhibiting oxidative stress and ferroptosis through Nrf2 pathway
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    sciencedirect.com/science/article/pii/S0361923025002084
  45. Apr 2025
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Molecular Mechanisms of Propofol-Induced Cognitive Impairment: Suppression of Critical Hippocampal Pathways
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70070
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    Hydroxysafflor yellow A inhibits neuronal ferroptosis and ferritinophagy in ischemic stroke
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    sciencedirect.com/science/article/pii/S0925443925002157
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    Retinal degeneration protein 3 mutants are associated with cell-cycle arrest and apoptosis
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  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human neural stem cell-derived exosomes activate PINK1/Parkin pathway to protect against oxidative stress-induced neuronal injury in ischemic stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC11971779/
  50. Mar 2025
  51. www.sciencedirect.com www.sciencedirect.com
    C30 reversed-phase HPLC analysis and in vitro bioactivity evaluation of decursin and decursinol angelate in Angelicae Gigantis Radix
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    sciencedirect.com/science/article/pii/S2405844025014744
  52. Dec 2024
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    Antiferroptotic properties of allicin and related organosulfur compounds—diallyl disulfide and diallyl trisulfide—from Garlic
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    sciencedirect.com/science/article/pii/S0278691524006902
  54. Nov 2024
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    Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis
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    sciencedirect.com/science/article/pii/S1550413124004029
  56. Oct 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433893/
  58. Sep 2024
  59. www.sciencedirect.com www.sciencedirect.com
    Bis-chalcones obtained via one-pot synthesis as the anti-neurodegenerative agents and their effect on the HT-22 cell line
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  60. Aug 2024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    2,3-Diphosphoglyceric Acid Alleviating Hypoxic-Ischemic Brain Damage through p38 MAPK Modulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11354455/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11317949/
  63. link.springer.com link.springer.com
    Mdivi-1 alleviates ferroptosis induced by hypoxia combined with propofol in HT22 cells by inhibiting excessive mitophagy
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    link.springer.com/article/10.1007/s11033-024-09812-y
  64. journals.lww.com journals.lww.com
    Exosomes derived from microglia overexpressing miR-124-3p alleviate neuronal endoplasmic reticulum stress damage after repetitive mild traumatic brain injury
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    journals.lww.com/nrronline/fulltext/2024/09000/exosomes_derived_from_microglia_overexpressing.33.aspx
  65. Jul 2024
  66. www.tandfonline.com www.tandfonline.com
    Study of the multitarget mechanism of Astragalus (HUANGQI) in the treatment of Alzheimer’s disease based on network pharmacology and molecular docking technology
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    tandfonline.com/doi/abs/10.1080/13880209.2024.2382962
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    Ferroptosis induces nucleolar stress as revealed by live-cell imaging using thioflavin T
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    sciencedirect.com/science/article/pii/S2590257124000233
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    Targeting the postsynaptic scaffolding protein PSD-95 enhances BDNF signaling to mitigate depression-like behaviors in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11223518/
  69. May 2024
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Accumulation of extracellular elastin-derived peptides disturbed neuronal morphology and neuron–microglia crosstalk in aged brain
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16039
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    The actin-binding protein CAP1 represses MRTF-SRF–dependent gene expression in mouse cerebral cortex
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    science.org/doi/10.1126/scisignal.adj0032
  72. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16400
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    Targeting the postsynaptic scaffolding protein PSD-95 enhances BDNF signaling to mitigate depression-like behaviors in mice
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    science.org/doi/10.1126/scisignal.adn4556
  74. Apr 2024
  75. www.sciencedirect.com www.sciencedirect.com
    Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity
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  76. Feb 2024
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neural stem cell-derived exosomes promote mitochondrial biogenesis and restore abnormal protein distribution in a mouse model of Alzheimer's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10883488/
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17099
  79. www.mdpi.com www.mdpi.com
    Neuroprotection via Carbon Monoxide Depends on the Circadian Regulation of CD36-Mediated Microglial Erythrophagocytosis in Hemorrhagic Stroke
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  80. Jan 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Characterization of Rat Hepatic Stellate Cell Line PAV-1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10297474/
  82. Nov 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural features localizing the ferroptosis inhibitor GIF-2197-r to lysosomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10620646/
  84. Oct 2023
  85. www.mdpi.com www.mdpi.com
    Neuroprotective Effects of Water Extract from Brown Algae Petalonia binghamiae in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
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    mdpi.com/1467-3045/45/10/531
  86. Sep 2023
  87. link.springer.com link.springer.com
    Deubiquitylating Enzyme OTUB1 Facilitates Neuronal Survival After Intracerebral Hemorrhage Via Inhibiting NF-κB-triggered Apoptotic Cascades
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    link.springer.com/article/10.1007/s12035-023-03676-2
  88. journals.physiology.org journals.physiology.org
    Mechanism of SOX10 in ferroptosis of hippocampal neurons after intracerebral hemorrhage via the miR-29a-3p/ACSL4 axis
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    journals.physiology.org/doi/10.1152/jn.00374.2022
  89. Aug 2023
  90. www.sciencedirect.com www.sciencedirect.com
    Ring finger protein 146-mediated long-chain fatty-acid-coenzyme A ligase 4 ubiquitination regulates ferroptosis-induced neuronal damage in ischemic stroke
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    sciencedirect.com/science/article/pii/S0306452223003494
  91. Jul 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The circular RNA Rap1b promotes Hoxa5 transcription by recruiting Kat7 and leading to increased Fam3a expression, which inhibits neuronal apoptosis in acute ischemic stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328278/
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  94. Jun 2023
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    Antiferroptotic Activities of Oxindole GIF-0726-r Derivatives: Involvement of Ferrous Iron Coordination and Free-Radical Scavenging Capacities
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  96. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astragaloside IV alleviates neuronal ferroptosis in ischemic stroke by regulating fat mass and obesity-associated—N6-methyladenosine—acyl-CoA synthetase long-chain family member 4 axis
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15871
  97. Apr 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulation of CDGSH iron sulfur domain 2 attenuates cerebral ischemia/reperfusion injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10075131/
  99. Jan 2023
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthesize heterogeneous biological knowledge via representation learning for Alzheimer’s disease drug repurposing
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    ncbi.nlm.nih.gov/pmc/articles/PMC9804117/
  101. Dec 2022
  102. www.jcancer.org www.jcancer.org
    Long noncoding RNA DSCR8 promotes the proliferation of liver cancer cells and inhibits apoptosis via the miR-22-3p/ARPC5 Axis
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    jcancer.org/v14p0035.htm
  103. www.sciencedirect.com www.sciencedirect.com
    Conditioned media of mouse macrophages modulates neuronal dynamics in mouse hippocampal cells
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    sciencedirect.com/science/article/pii/S1567576922010335
  104. Nov 2022
  105. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Continued P2X7 Activation Leads to Mitochondrial Fission and Compromising Microglial Phagocytosis after Subarachnoid Haemorrhage
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15712
  106. Oct 2022
  107. pubs.acs.org pubs.acs.org
    Haloperidol Prevents Oxytosis/Ferroptosis by Targeting Lysosomal Ferrous Ions in a Manner Independent of Dopamine D2 and Sigma-1 Receptors
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    pubs.acs.org/doi/full/10.1021/acschemneuro.2c00398
  108. www.sciencedirect.com www.sciencedirect.com
    Thiamine insufficiency induces Hypoxia Inducible Factor-1α as an upstream mediator for neurotoxicity and AD-like pathology
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    sciencedirect.com/science/article/pii/S1044743122000914
  109. Jun 2022
  110. 52.53.155.43 52.53.155.43
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    Effect of ferroptosis inhibitors oxindole-curcumin hybrid compound and N,N-dimethylaniline derivatives on rotenone-induced oxidative stress
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    sciencedirect.com/science/article/pii/S0014299922003806
  112. Apr 2022
  113. pubs.acs.org pubs.acs.org
    Identification of Novel Oxindole Compounds That Suppress ER Stress-Induced Cell Death as Chemical Chaperones
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    pubs.acs.org/doi/full/10.1021/acschemneuro.2c00064
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Screening and Structure–Activity Relationship of D2AAK1 Derivatives for Potential Application in the Treatment of Neurodegenerative Diseases
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    ncbi.nlm.nih.gov/pmc/articles/PMC9000546/
  115. journals.lww.com journals.lww.com
    Obstructive sleep apnea aggravates neuroinflammation and... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2022/11000/Obstructive_sleep_apnea_aggravates.43.aspx
  116. link.springer.com link.springer.com
    In vitro and in vivo evaluation of antioxidant and neuroprotective properties of antipsychotic D2AAK1
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    link.springer.com/article/10.1007/s11064-022-03570-8
  117. Mar 2022
  118. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system
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  142. Sep 2020
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  152. Nov 2017
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