187 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13238812/
  3. Jun 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory
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    sciencedirect.com/science/article/pii/S2666379126002569
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CENPA as a Genome Stability–Associated Biomarker in Hepatocellular Carcinoma: Multiomics Analysis and Experimental Validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13201903/
  6. May 2026
  7. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Master Regulator SMC1A, Stabilized by N6-Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.75616
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MAPRE2 is associated with macrophage-enriched innate immune dysregulation and malignant phenotypes in hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13215804/
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    USP22 Inhibition Potentiates GPC3 Chimeric Antigen Receptor Macrophages Efficacy in Hepatocellular Carcinoma by Downregulating Tumor CD24 Expression
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    sciencedirect.com/science/article/pii/S0304383526003563
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hepatic stellate cell-specific METTL3 deficiency promotes hepatocellular carcinoma progression via BMP10-SMAD1/5/8 signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13168861/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP25 aggravates liver cancer development and impairs chemosensitivity by limiting LATS1 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13172046/
  12. aacrjournals.org aacrjournals.org
    Lipid Nanoparticle-Encapsulated mRNAs Encoding Tumor-Specific Toxin Proteins Selectively Target Cancer Cells and Stimulate T Cell Infiltration
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    aacrjournals.org/cancerres/article/85/19/3706/765871/Lipid-Nanoparticle-Encapsulated-mRNAs-Encoding
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    A functional SNP rs12718466 in APOA1 promoter modulates gene expression via interaction with SOX7
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    sciencedirect.com/science/article/pii/S0021925826019733
  14. Apr 2026
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ILF3 Regulates Cell Proliferation and Metastasis by Competitively Antagonizing the Interaction Between HMGCL and USP38 in Hepatocellular Carcinoma
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    onlinelibrary.wiley.com/doi/10.1155/humu/2654435
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    Dual Specificity Phosphatase 4 Enhances Immunotherapy Response by Inhibiting TGF-β1 Secretion in Hepatocellular Carcinoma
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    mdpi.com/2072-6694/18/8/1289
  17. www.biorxiv.org www.biorxiv.org
    SImBA-SiQuAl: a new tool enabling high-content high-throughput phenotypic profiling of 3D microtumours
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    biorxiv.org/content/10.64898/2026.04.14.718366v1
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCT2 Orchestrates Glycolysis and Exosome-Mediated M2 Macrophage Polarization in HCC tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13085899/
  19. aacrjournals.org aacrjournals.org
    Glypican-3-Targeted PET Imaging for Precise Diagnosis of Hepatocellular Carcinoma: From Bench to Bedside
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    aacrjournals.org/clincancerres/article/32/3/550/772039/Glypican-3-Targeted-PET-Imaging-for-Precise
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    Peroxisome-derived and liver-specific hydroxyacid oxidase 1-mediated hydrogen peroxide promotes ferroptosis by augmenting peroxisomal ROS
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    sciencedirect.com/science/article/pii/S2090123226003425
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    Bio-inspired fractal-structured gel-drugs enable enhancing deep tumor penetration for efficient chemotherapy of hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S0168365926003019
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RASGEF1B suppresses hepatocellular carcinoma through the ALDH7A1/Betaine/SNAI1 metabolic‒epigenetic axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13041341/
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    Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2666379126001345
  24. Mar 2026
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NARS1 Enhances HCC Proliferation by Stimulating NF-κB Signaling Pathway
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    onlinelibrary.wiley.com/doi/10.1155/humu/8809532
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    Deep-learning-based de novo discovery and design of therapeutics that reverse disease-associated transcriptional phenotypes
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    sciencedirect.com/science/article/pii/S0092867426002230
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    A Niclosamide Prodrug SSL-0024 with Enhanced Bioavailability Suppresses Hepatocellular Carcinoma via Multi-Pathway Signaling Inhibition
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    biorxiv.org/content/10.64898/2026.03.06.710248v1
  28. 54.241.53.176 54.241.53.176
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    USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis
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    sciencedirect.com/science/article/pii/S2589004226003020
  30. Feb 2026
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Label‐free imaging of intracellular structures in living mammalian cells via external apodization phase‐contrast microscopy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12914761/
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    Diverse Meroterpenoids from the Endophytic Fungus Penicillium oxalicum and Their Cytotoxic Activities
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503124
  33. Jan 2026
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epithelial–Mesenchymal Transition and Stress Adaptations Underlie Yttrium-90 Resistance in Liver Cancer Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC12824473/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic Insights into the Economic Toll of Cell Line Misidentification: A Comprehensive Review
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  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct Regulation of the ARF and TAp73 Tumor Suppressor Genes by the Transcription Factor E2F1 Enables Discrimination of Cancer Cells from Normal Growing Cells
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    Guaianolide dimer KGA-1002 targets GRP94 and triggers unfolded protein response-associated degradation of SKP2/AKT axis as a novel antihepatoma agent
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    A Novel Quinolone JH62 (E-2-(Tridec-4-en-1-yl)-quinolin-4(1H)-one) from Pseudomonas aeruginosa Exhibits Potent Anticancer Activity
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    AARS1-mediated AKR1B10 lactylation stabilizes an aerobic glycolysis-positive feedback loop to drive lenvatinib resistance in hepatocellular carcinoma
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    onlinelibrary.wiley.com/doi/full/10.1002/ctm2.70561
  40. Dec 2025
  41. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Targeting PRDX6-dependent localization and function of GPX4 enhances ferroptosis-mediated tumor suppression
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    PFKL Inhibition by DT-13: A Novel Approach to Combat Hepatocellular Carcinoma
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    onlinelibrary.wiley.com/doi/10.1155/ijh/5211859
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    G9a epigenetically suppresses CXCL10 expression and inhibits anti-tumor immunity in hepatocellular carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.70284
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    E7386 enhances lenvatinib’s antitumor activity in preclinical models and human hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666316/
  45. Nov 2025
  46. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    A metabolic atlas of mouse aging
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    Menin-MLL1 complex cooperates with NF-Y to promote hepatocellular carcinoma survival
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  48. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    SENP3 Promotes Hepatocyte Steatosis via De-SUMOylation of SREBP2
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/cbf.70141
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Diagnosis and Treatment Response Monitoring of Liver Cancer using Glypican-3-Targeted Single Domain Antibody Positron Emission Tomography
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    pmc.ncbi.nlm.nih.gov/articles/PMC12604626/
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    UDP-GlcUA triggers PKR kinase activity to promote liquid-liquid phase separation of TOP2A and enhances radioimmunotherapy resistance
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    sciencedirect.com/science/article/pii/S1097276525008287
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Magnetic Resonance Imaging Using a Chimeric Anti-Glypican-3 Antibody Conjugated with Gadolinium Selectively Detects Glypican-3-Positive Hepatocellular Carcinoma In Vitro and In Vivo
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  52. Oct 2025
  53. www.sciencedirect.com www.sciencedirect.com
    Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2211124725012318
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    Development of the FGFR4-ADC bearing the ferroptosis inducer sulfasalazine for hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004225019790
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    The upregulation of GDF15 is controlled epigenetically by oncogenic TCF19 signaling in human hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S258900422501764X
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    CBX4 acetoacetylation as an inhibitory mechanism of HIF-1α activity
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    sciencedirect.com/science/article/pii/S2451945625003009
  57. www.sciencedirect.com www.sciencedirect.com
    Catenibacterium mitsuokai promotes hepatocellular carcinogenesis by binding to hepatocytes and generating quinolinic acid
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    sciencedirect.com/science/article/pii/S1550413125003869
  58. Sep 2025
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    miR-199a-5p/GPR89A axis modulates sorafenib resistance in hepatocellular carcinoma through glutamate metabolic reprogramming
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    pmc.ncbi.nlm.nih.gov/articles/PMC12457768/
  60. journals.asm.org journals.asm.org
    HBV-encoded circRNA-5 promotes hepatocellular carcinoma progression by regulating the miR-9-3p/Hippo signaling axis
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    journals.asm.org/doi/10.1128/spectrum.01439-25
  61. Aug 2025
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11949624/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319405/
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    Computational framework for prioritizing candidate compounds overcoming the resistance of pancancer immunotherapy
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    sciencedirect.com/science/article/pii/S2666379125003490
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    Targeting MCM10 disrupts cancer stemness and counteracts sorafenib resistance in hepatocellular carcinoma
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    nature.com/articles/s41417-025-00946-0
  66. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    ASH2L-K312-Lac Stimulates Angiogenesis in Tumors to Expedite the Malignant Progression of Hepatocellular Carcinoma
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509477
  67. Jul 2025
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thyroid hormone suppresses cell growth by regulating CDK2 and cyclin E1 expression via Hepsin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12256398/
  69. www.nature.com www.nature.com
    IFNγ augments TKI efficacy by alleviating protein unfolding stress to promote GSDME-mediated pyroptosis in hepatocellular carcinoma
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    nature.com/articles/s41419-025-07839-y
  70. www.frontiersin.org www.frontiersin.org
    Frontiers | TREM1 is essential for maintaining stemness of liver cancer stem-like cells in hepatocellular carcinoma
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    frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1618342/full
  71. Jun 2025
  72. www.cell.com www.cell.com
    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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  74. May 2025
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    ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression
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  76. Apr 2025
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    Downregulation of PD-L1 expression by Wnt pathway inhibition to enhance PD-1 blockade efficacy in hepatocellular carcinoma
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    link.springer.com/article/10.1186/s13062-025-00645-8
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    RAF1 kinase contributes to autophagic lysosome reformation
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  79. Mar 2025
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    Anti-tumor efficacy and safety of AEV01 in preclinical glioblastoma and hepatocellular carcinoma models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11865564/
  82. Feb 2025
  83. www.sciencedirect.com www.sciencedirect.com
    AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity
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  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11832924/
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    Lactate drives senescence-resistant lineages in hepatocellular carcinoma via histone H2B lactylation of NDRG1
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    sciencedirect.com/science/article/pii/S0304383525001314
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    CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors
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    sciencedirect.com/science/article/pii/S2666379125000382
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    ENTPD8 overexpression enhances anti-PD-L1 therapy in hepatocellular carcinoma via miR-214-5p inhibition
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    sciencedirect.com/science/article/pii/S2589004225000793
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    Machine learning-based integration reveals immunological heterogeneity and the clinical potential of T cell receptor (TCR) gene pattern in hepatocellular carcinoma
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    link.springer.com/article/10.1007/s10495-025-02080-6
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    Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3
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  90. Jan 2025
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    OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth
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  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MAF1 inhibits hepatocarcinogenesis by fostering an immunostimulatory tumor microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11749189/
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    Re-evaluation of the relationship between PrPc expression and patient prognosis in primary esophageal squamous cell carcinoma and primary hepatocellular carcinoma
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    nature.com/articles/s41598-024-82398-4
  94. Dec 2024
  95. www.nature.com www.nature.com
    Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
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    nature.com/articles/s41418-024-01439-7
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    Carbonic anhydrase 2 facilitates sorafenib resistance by counteracting MCT4-mediated intracellular pH dysregulation in HCC
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    sciencedirect.com/science/article/pii/S2211124724013470
  98. Nov 2024
  99. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers
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    ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma
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    Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
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  102. Oct 2024
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984770/
  104. Aug 2024
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  243. Nov 2018
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