158 Matching Annotations
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    The AMPK-ALDH7A1 axis drives metabolic reprogramming and anti-tumor immunity in hepatocellular carcinoma via KDM5C inhibition
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    sciencedirect.com/science/article/pii/S1534580726003928
  3. Oct 2026
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    Systemic antitumor responses to hypofractionated radiotherapy plus Poly(I:C) in advanced hepatocellular carcinoma: A phase 2 trial
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    Liver-specific amino acid metabolism impacts on efficacy of cancer immunotherapy
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    XIAP inhibition augments personalized neoantigen vaccine-driven antitumor immunity in orthotopic hepatocellular carcinoma
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    Cancer competition for vitamin B2 creates metabolic checkpoint for T cell ferroptosis
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    Fungus Rhizopus arrhizus promotes MASLD-associated hepatocellular carcinoma through generating kynurenic acid
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    Targeting a site of vulnerability on circumsporozoite protein inhibits Plasmodium vivax malaria infection
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  10. Sep 2026
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    Lipopolymer Nanoparticle-Mediated In Vivo CRISPR-Cas9 Editing of Mrg15 Restores Mitochondrial Mitophagy to Alleviate Metabolic-Associated Steatohepatitis
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    Metabolic Reprogramming of NSUN2-Mediated m5C Modification Promotes the Progression of Hepatocellular Carcinoma by Restricting Natural Killer Cell-Mediated Cytotoxicity
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  13. Aug 2026
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    Targeting Circulating Fatty Acid Binding Protein 4 Ameliorates Obesity-Associated Hepatic Steatosis
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    Integrative 3D genome and epigenomic analysis identifies TP53RK and SYBU as critical regulators of stemness and anti-tumor immunity in HCC
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    The coordinated actions of metformin in the intestine and liver improves hyperglycemia
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  17. Jul 2026
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    UFMylation Suppresses Hepatocellular Carcinoma Metastasis by Inhibiting β-catenin-Driven Hybrid EMT and NK Cell Evasion
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    Targeting p21-High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
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  21. Jun 2026
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    Bile acids mediate liver-bone marrow crosstalk
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    Bile acid retention in efferocytic macrophages shapes their inflammatory status during cholangitis
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    Hepatitis B virus promotes hepatocellular carcinogenesis by activating IL-6-dependent tumor-macrophage crosstalk and M2-like macrophage polarization
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    Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory
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    Targeted extracellular vesicle-photoimmunotherapy remodels stromal-immune microenvironment to boost chemo-immunotherapy in preclinical models
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  27. May 2026
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    Hepatic stellate cell-specific METTL3 deficiency promotes hepatocellular carcinoma progression via BMP10-SMAD1/5/8 signaling
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    Intra-tumoral tertiary lymphoid structures characterized by a B cell-related signature elicit antitumor effect through HAPLN3 in hepatocellular carcinoma
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  30. Apr 2026
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    Tumor-Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T-Cell Infiltration and Limiting Myeloid Cell-Mediated Immunosuppression
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    Plasmin promotes hepatocellular carcinoma invasion and metastasis via CXCR4-mediated activation of PI3K/AKT/mTOR signaling
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    Bio-inspired fractal-structured gel-drugs enable enhancing deep tumor penetration for efficient chemotherapy of hepatocellular carcinoma
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    Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma
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  45. Mar 2026
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    Radiation-Enhanced CD24 Membrane Trafficking via GPI Anchoring Mediates Anti-Tumor Immune Evasion
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  51. Feb 2026
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis
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    A mitochondrion–targeted natural polyphenolic copper carrier overcomes tumor resistance to cisplatin by potentiating cuproptosis
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    Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis
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  57. Jan 2026
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    Engineered CAR-NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity
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    Mitochondrial dsRNA: A Hidden Source of Immunogenic RNA in ADAR1 Deficiency
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    Uridine depletion impairs CD8⁺ T cell antitumor activity through N-glycosylation
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    AARS1-mediated AKR1B10 lactylation stabilizes an aerobic glycolysis-positive feedback loop to drive lenvatinib resistance in hepatocellular carcinoma
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  63. Dec 2025
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    Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD-L1 Expression and Acts as a Target to Enhance Anti-PD-1 Efficacy
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    G9a epigenetically suppresses CXCL10 expression and inhibits anti-tumor immunity in hepatocellular carcinoma
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  68. Nov 2025
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    Laminin β1 stimulates the Hippo-YAP1 pathway to advance the progression and lenvatinib resistance in hepatocellular carcinoma
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  72. Oct 2025
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    Quercetin-derived microbial metabolite DOPAC potentiates CD8+ T cell anti-tumor immunity via NRF2-mediated mitophagy
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    Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma
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    Boosting mRNA Therapeutics: pHLIP Enhances Endosomal Escape and Gene Expression in Lipid Nanoparticle
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    Mild Photothermal Bimetallic Mesoporous Nanozyme Triggers Immunogenic Cell Death and Immune Contexture Remodeling for Precision Hepatocellular Carcinoma Treatment
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    Tumor-derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma
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    Catenibacterium mitsuokai promotes hepatocellular carcinogenesis by binding to hepatocytes and generating quinolinic acid
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  80. Sep 2025
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD24 recruits tumor-associated neutrophils to promote the progression of hepatocellular carcinoma
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  82. Aug 2025
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    Enhanced formation of tertiary lymphoid structures shapes the anti-tumor microenvironment in hepatocellular carcinoma after FOLFOX-HAIC therapy
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    Isosilybin B: a potential novel therapeutic agent with hepatoprotective, anticancer and antifibrotic properties
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    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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    Computational framework for prioritizing candidate compounds overcoming the resistance of pancancer immunotherapy
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  88. Jul 2025
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    Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL
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    An alternate receptor for adeno-associated viruses
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    IFNγ augments TKI efficacy by alleviating protein unfolding stress to promote GSDME-mediated pyroptosis in hepatocellular carcinoma
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  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Artesunate-mycophenolate Mofetil Dimer Micelles Alleviate Allogeneic Skin Graft Rejection by Inhibiting the TLR-4 Pathway in Macrophages
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  93. Jun 2025
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    Synergistic and toxicity-reducing effects of acteoside as an adjuvant therapy of oxaliplatin against hepatocellular carcinoma
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    LMNB2-mediated high PD-L1 transcription triggers the immune escape of hepatocellular carcinoma
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    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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  98. May 2025
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    Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV
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  100. Apr 2025
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