38 Matching Annotations
  1. Dec 2023
  2. 52.53.155.43 52.53.155.43
    Lysophosphotidylinositols (LysoPIs) are upregulated following human ß-cell loss and act to potentiate insulin release.
    1
    1. scibot 01 Dec 2023
      RRID:CVCL_0351

      DOI: 10.2337/db23-0205

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    52.53.155.43/cd72489e1556c808acbc0cfde44ddd59335197ad/db230205-html.html
  3. Nov 2023
  4. www.mdpi.com www.mdpi.com
    Human Pancreatic Islets React to Glucolipotoxicity by Secreting Pyruvate and Citrate
    1
    1. scibot 18 Nov 2023
      RRID:CVCL_0351

      DOI: 10.3390/nu15224791

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    mdpi.com/2072-6643/15/22/4791
  5. Oct 2023
  6. www.nature.com www.nature.com
    Warburg-associated acidification represses lactic fermentation independently of lactate, contribution from real-time NMR on cell-free systems
    1
    1. scibot 20 Oct 2023
      RRID:CVCL_0351

      DOI: 10.1038/s41598-023-44783-3

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    nature.com/articles/s41598-023-44783-3
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
    1
    1. scibot 14 Oct 2023
      RRID:CVCL_0351

      DOI: 10.1016/j.isci.2023.107956

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    ncbi.nlm.nih.gov/pmc/articles/PMC10562789/
  8. Apr 2023
  9. www.sciencedirect.com www.sciencedirect.com
    FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
    1
    1. scibot 19 Apr 2023
      RRID:CVCL_0351

      DOI: 10.1016/j.cmet.2023.03.018

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    sciencedirect.com/science/article/pii/S1550413123001237
  10. Mar 2023
  11. www.mdpi.com www.mdpi.com
    BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis
    1
    1. scibot 24 Mar 2023
      RRID:CVCL_0351

      DOI: 10.3390/ijms24065657

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    mdpi.com/1422-0067/24/6/5657
  12. Dec 2022
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Apollo-NADP+ to Image NADPH Generation in Pancreatic Beta-Cell Organelles
    1
    1. scibot 02 Dec 2022
      RRID:CVCL_0351

      DOI: 10.1021/acssensors.2c01174

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    ncbi.nlm.nih.gov/pmc/articles/PMC9706804/
  14. Aug 2022
  15. www.nature.com www.nature.com
    Loss of Nexmif results in the expression of phenotypic variability and loss of genomic integrity
    1
    1. scibot 16 Aug 2022
      RRID:CVCL_0351

      DOI: 10.1038/s41598-022-17845-1

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    nature.com/articles/s41598-022-17845-1
  16. www.sciencedirect.com www.sciencedirect.com
    Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine
    1
    1. scibot 12 Aug 2022
      RRID:CVCL_0351

      DOI: 10.1016/j.isci.2022.104771

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    sciencedirect.com/science/article/pii/S2589004222010434
  17. Jul 2022
  18. www.sciencedirect.com www.sciencedirect.com
    The alternative analog plasticizer BPS displays similar phenotypic and metabolomic responses to BPA in HepG2 and INS-1E cells
    1
    1. scibot 02 Jul 2022
      RRID:CVCL_0351

      DOI: 10.1016/j.fct.2022.113266

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    sciencedirect.com/science/article/pii/S0278691522004641
  19. May 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vitro Assays to Identify Metabolism-Disrupting Chemicals with Diabetogenic Activity in a Human Pancreatic β-Cell Model
    1
    1. scibot 18 May 2022
      RRID:CVCL_0351

      DOI: 10.3390/ijms23095040

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    ncbi.nlm.nih.gov/pmc/articles/PMC9102687/
  21. Apr 2022
  22. www.sciencedirect.com www.sciencedirect.com
    G protein-coupled estrogen receptor activation by bisphenol-A disrupts the protection from apoptosis conferred by the estrogen receptors ERα and ERβ in pancreatic beta cells
    1
    1. scibot 20 Apr 2022
      RRID:CVCL_0351

      DOI: 10.1016/j.envint.2022.107250

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    sciencedirect.com/science/article/pii/S0160412022001763
  23. Feb 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Soft X-ray tomography to map and quantify organelle interactions at the mesoscale
    2
    1. scibot 11 Feb 2022
      RRID:CVCL_0351

      DOI: 10.1016/j.str.2022.01.006

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    2. scibot 11 Feb 2022
      RRID:CVCL_0351

      DOI: 10.1016/j.str.2022.01.006

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    sciencedirect.com/science/article/pii/S0969212622000065
  25. Jan 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Divergent effects of HIV reverse transcriptase inhibitors on pancreatic beta-cell function and survival: Potential role of oxidative stress and mitochondrial dysfunction
    1
    1. scibot 29 Jan 2022
      RRID:CVCL_0351

      DOI: 10.1016/j.lfs.2022.120329

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    sciencedirect.com/science/article/pii/S0024320522000297
  27. link.springer.com link.springer.com
    Glucolipotoxicity promotes the capacity of the glycerolipid/NEFA cycle supporting the secretory response of pancreatic beta cells
    1
    1. scibot 13 Jan 2022
      RRID:CVCL_0351

      DOI: 10.1007/s00125-021-05633-x

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    link.springer.com/article/10.1007/s00125-021-05633-x
  28. Sep 2021
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genetically Encoded Protein Thermometer Enables Precise Electrothermal Control of Transgene Expression
    1
    1. scibot 10 Sep 2021
      RRID:CVCL_0351

      DOI: 10.1002/advs.202101813

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    onlinelibrary.wiley.com/doi/10.1002/advs.202101813
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of Alpha Cells in the Self-Assembly of Bioengineered Islets
    1
    1. scibot 04 Sep 2021
      RRID:CVCL_0351

      DOI: 10.1089/ten.tea.2020.0080

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    ncbi.nlm.nih.gov/pmc/articles/PMC8392094/
  31. Aug 2021
  32. www.sciencedirect.com www.sciencedirect.com
    The role of mitochondrial apoptotic pathway in islet amyloid-induced β-cell death
    1
    1. scibot 17 Aug 2021
      RRID:CVCL_0351

      DOI: 10.1016/j.mce.2021.111424

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    sciencedirect.com/science/article/pii/S0303720721002689
  33. link.springer.com link.springer.com
    Untitled document
    1
    1. scibot 10 Aug 2021
      CVCL_0351

      DOI: 10.1007/s00125-018-4782-0

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    link.springer.com/article/10.1007/s00125-018-4782-0
  34. www.sciencedirect.com www.sciencedirect.com
    Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes
    1
    1. scibot 04 Aug 2021
      RRID:CVCL_0351

      DOI: 10.1016/j.celrep.2021.109490

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    sciencedirect.com/science/article/pii/S2211124721009177
  35. www.sciencedirect.com www.sciencedirect.com
    Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion coupling
    1
    1. scibot 01 Aug 2021
      RRID:CVCL_0351

      DOI: 10.1016/j.bbamcr.2019.118619

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0167488919302277
  36. Jul 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Phosphoproteomics Reveals the GSK3-PDX1 Axis as a Key Pathogenic Signaling Node in Diabetic Islets
    1
    1. scibot 31 Jul 2021
      RRID:CVCL_0351

      DOI: 10.1016/j.cmet.2019.02.012

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    sciencedirect.com/science/article/pii/S1550413119300762
  38. www.sciencedirect.com www.sciencedirect.com
    Conditioned media from contracting skeletal muscle potentiates insulin secretion and enhances mitochondrial energy metabolism of pancreatic beta-cells
    1
    1. scibot 30 Jul 2021
      RRID:CVCL_0351

      DOI: 10.1016/j.metabol.2018.11.004

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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S002604951830235X
  39. Jun 2021
  40. www.sciencedirect.com www.sciencedirect.com
    MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity
    1
    1. scibot 23 Jun 2021
      RRID:CVCL_0351

      DOI: 10.1016/j.bbadis.2021.166199

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    sciencedirect.com/science/article/pii/S0925443921001320
  41. May 2021
  42. academic.oup.com academic.oup.com
    Endothelial cell-derived triosephosphate isomerase attenuates insulin secretion from pancreatic beta cells of male rats
    1
    1. scibot 11 May 2021
      RRID:CVCL_0351

      DOI: 10.1210/endocr/bqaa234

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    academic.oup.com/endo/article/162/3/bqaa234/6042346
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amino acid restriction alters survival mechanisms in pancreatic beta cells: possible role of the PI3K/Akt pathway
    1
    1. scibot 01 May 2021
      RRID:CVCL_0351

      DOI: 10.1007/s00394-021-02568-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC8081284/
  44. Apr 2021
  45. www.sciencedirect.com www.sciencedirect.com
    AQP8 is a crucial H2O2 transporter in insulin-producing RINm5F cells
    1
    1. scibot 02 Apr 2021
      RRID:CVCL_0351

      DOI: 10.1016/j.redox.2021.101962

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      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S2213231721001105
  46. Dec 2020
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography
    1
    1. scibot 19 Dec 2020
      CVCL_0351

      DOI: 10.1126/sciadv.abc8262

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7725475/
  48. www.sciencedirect.com www.sciencedirect.com
    Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes
    1
    1. scibot 07 Dec 2020
      RRID:CVCL_0351

      DOI: 10.1016/j.celrep.2020.108466

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    sciencedirect.com/science/article/pii/S2211124720314558
  49. Jan 2020
  50. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Differential effect of glucose on ER-mitochondria Ca2+ exchange participates to insulin secretion and to glucotoxicity-mediated dysfunction of β cells.
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_0351

      DOI: 10.2337/db18-1112

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    diabetes.diabetesjournals.org/content/68/9/1778
  51. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 13 Jan 2020
      CVCL_0351

      DOI: 10.1111/bph.14757

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14757
  52. www.sciencedirect.com www.sciencedirect.com
    Conditioned media from contracting skeletal muscle potentiates insulin secretion and enhances mitochondrial energy metabolism of pancreatic beta-cells
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_0351

      DOI: 10.1016/j.metabol.2018.11.004

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    sciencedirect.com/science/article/pii/S002604951830235X
  53. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amino acid restriction increases β‐cell death under challenging conditions
    1
    1. scibot 12 Jan 2020
      RRID:CVCL_0351

      DOI: 10.1002/jcp.28389

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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.28389
  54. Nov 2018
  55. link.springer.com link.springer.com
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_0351

      Curator: @evieth

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    link.springer.com/article/10.1007/s00424-018-2215-z
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_0351

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    ncbi.nlm.nih.gov/pmc/articles/PMC6023166/
  57. Nov 2017
  58. academic.oup.com academic.oup.com
    Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis
    1
    1. scibot 08 Nov 2017
      CVCL_0351

      Curator: @kaitlinsung

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    academic.oup.com/endo/article/158/8/2503/3861370/Protective-Role-of-Complement-C3-Against-Cytokine
  59. academic.oup.com academic.oup.com
    Guanabenz Sensitizes Pancreatic β Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis
    1
    1. scibot 08 Nov 2017
      CVCL_0351

      Curator: @bandrow

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    academic.oup.com/endo/article/158/6/1659/3058741/Guanabenz-Sensitizes-Pancreatic-Cells-to-Lipotoxic