141 Matching Annotations
  1. Last 7 days
  2. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Synthesis and Biological Evaluation of 5-Arylpyrazoles as Potential MCT 1 Inhibitors Targeting Lactate Transport
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.70555
  3. Oct 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uncovering MYOF as a novel therapeutic target in glioblastoma: mechanistic insights and drug discovery
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    pmc.ncbi.nlm.nih.gov/articles/PMC13645784/
  5. Aug 2026
  6. www.sciencedirect.com www.sciencedirect.com
    Repurposing Nelfinavir: AIM2 inflammasome-associated anti-tumor effects in Glioblastoma
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    sciencedirect.com/science/article/pii/S0925443926002942
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    COPS7B Drives Malignant Progression of Glioblastoma Through Translational Upregulation of the Downstream Functional Effector CLU
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    pmc.ncbi.nlm.nih.gov/articles/PMC13467472/
  8. www.biorxiv.org www.biorxiv.org
    NLRP12-mediated Glioblastoma-Astrocyte Cross-talk Promotes Tumor Growth
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    biorxiv.org/content/10.1101/2025.11.13.688374v1
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel oncolytic herpes simplex virus type 2 induces polarization of tumor-associated macrophages and remodels the immune microenvironment in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13442803/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring Disulfide Bridge as a Tool to Improve Pioglitazone’s Neuroprotective Potential: Toward the Development of Prolonged‐Acting MAO‐B/PPARγ Modulators
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    pmc.ncbi.nlm.nih.gov/articles/PMC13420967/
  11. Jul 2026
  12. aacrjournals.org aacrjournals.org
    Oncolytic HSV-1-Mediated JAG1 Blockade Induces Glioma Senescence-Associated Secretory Phenotype to Increase Macrophage Activation and Cetuximab-Mediated Senolysis
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    aacrjournals.org/cancerres/article/86/5/1232/774877/Oncolytic-HSV-1-Mediated-JAG1-Blockade-Induces
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    Lactate binds and inhibits the innate immune sensor STING to promote tumor immune evasion
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    sciencedirect.com/science/article/pii/S1074761326002554
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Feasibility and optimal imaging time window for intraperitoneal versus intravenous injection of a macrocyclic gadolinium-based contrast agent in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13319980/
  15. www.mdpi.com www.mdpi.com
    Potent Anti-Glioblastoma Effects of Next-Generation MNK Inhibitors
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    mdpi.com/2072-6694/18/13/2086
  16. Jun 2026
  17. www.sciencedirect.com www.sciencedirect.com
    Small-molecule inhibitors of the protein kinase DYRK as potential therapeutic candidates in cancer
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    sciencedirect.com/science/article/pii/S2451945626001571
  18. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose-driven glioblastoma
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70274
  19. May 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CREsted: modeling genomic and synthetic cell-type-specific enhancers across tissues and species
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    pmc.ncbi.nlm.nih.gov/articles/PMC13167471/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AI-driven network pharmacology and multi-omics validation identify KCNH2 as a prognostic biomarker and candidate therapeutic vulnerability of Acorus tatarinowii in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13149083/
  22. Apr 2026
  23. aacrjournals.org aacrjournals.org
    ACYP2 induces temozolomide resistance in glioblastoma by promoting PARP1-mediated DNA damage repair
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    aacrjournals.org/mcr/article/24/1/7/771152/ACYP2-Induces-Temozolomide-Resistance-in
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    mTORC1 activity suppresses ferroptosis through a SCARB1-dependent HDL-tocopherol uptake pathway
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    sciencedirect.com/science/article/pii/S1097276526001954
  25. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    JOSD1 Deubiquitinates Twist1 and Facilitates Epithelial–Mesenchymal Transition in Glioblastoma
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/cbf.70208
  26. 54.241.53.176 54.241.53.176
    2026.03.31.715305.full-html.html
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  27. aacrjournals.org aacrjournals.org
    Combined inactivation of MEK and mTOR can lead to synergistic cell death in glioblastoma models and associates with NF1-deficiency and a mesenchymal subtype
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    aacrjournals.org/mct/article/24/12/1878/768319/Combined-Inactivation-of-MEK-and-mTOR-Can-Lead-to
  28. Mar 2026
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma Pathophysiology
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    onlinelibrary.wiley.com/doi/10.1002/jcp.70163
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    Rap1b promotes glioma growth and stemness via regulation of Notch1 and VEGFR2 signaling pathways
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    sciencedirect.com/science/article/pii/S0898656826001075
  31. Feb 2026
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Repurposing the DNA Labeling Agent EdU for Therapy Against Heterogeneous Patient Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316568/
  33. Jan 2026
  34. www.sciencedirect.com www.sciencedirect.com
    Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
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    sciencedirect.com/science/article/pii/S155041312600001X
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    CRISPR activation screens map the genomic landscape of cancer glycome remodeling
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    sciencedirect.com/science/article/pii/S2666979X26000017
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    Targeted degradation of CD24 by a transferrin receptor-engaging bispecific degrader enhances antitumor immunity
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    sciencedirect.com/science/article/pii/S0006295226000523
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High‐Throughput 3D Glioblastoma Model in Glycosaminoglycan Hydrogels for Personalized Therapeutic Screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12805317/
  38. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Lipid Droplet-Localized Spindle Apparatus Coiled-Coil Protein 1 Regulates Lipid Droplet Distribution
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511960
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    PRSS23 orchestrates nonclassical ferroptosis resistance in glioblastoma by modulating chromatin accessibility via the NCAPD3/YY1/MBOAT2 axis
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    sciencedirect.com/science/article/pii/S2352304225004842
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    Nanotherapy Targeting miR-10b Improves Survival in Orthotopic Glioblastoma Models
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    mdpi.com/2079-4983/17/1/15
  41. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F-Actin Formation and Facilitate Double-strand DNA Breaks Repair in TMZ-Resistant Glioblastoma
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202513632
  42. Dec 2025
  43. 54.241.53.176 54.241.53.176
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  44. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    CUDC-907 inhibits glioblastoma and enhances glioblastoma sensitivity to temozolomide by inhibiting DNA damage repair
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    sciencedirect.com:5037/science/article/pii/S2352304225004374
  45. Nov 2025
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic potential of valsartan in overcoming chemoresistance in human glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12644396/
  47. www.biorxiv.org www.biorxiv.org
    Repurposing Nelfinavir: AIM2 Inflammasome-Driven Anti-tumor Effects in Glioblastoma
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    biorxiv.org/content/10.1101/2025.11.11.687819v1
  48. Oct 2025
  49. www.biorxiv.org www.biorxiv.org
    Combinatorial Treatment of Glioblastoma with Temozolomide (TMZ) Plus 5-Ethynyl-2’-deoxyuridine (EdU)
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    biorxiv.org/content/10.1101/2025.10.21.683081v2
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    Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3
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    sciencedirect.com/science/article/pii/S2589004225019364
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Coronin 1 Loss in Tumor Cells of Glioblastoma Patients Leads to Enhanced Tumor Aggressiveness
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70261
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    An optimized click chemistry method allows visualization of proliferating neuronal progenitors in the mouse brain
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    sciencedirect.com/science/article/pii/S2667237525002449
  53. www.sciencedirect.com www.sciencedirect.com
    “Cytochrome P450 2B6 Downregulation by Cell-Penetrating Dominant-Negative ATF5 Peptide in Glioblastoma Cells.”
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    sciencedirect.com/science/article/pii/S0090955625094887
  54. Sep 2025
  55. www.sciencedirect.com www.sciencedirect.com
    mTOR inhibition reprograms cellular lipid homeostasis by inducing alternative lipid uptake and promoting cholesterol transport
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    sciencedirect.com/science/article/pii/S1097276525007063
  56. Jul 2025
  57. link.springer.com link.springer.com
    Tunneling nanotubes between glioblastoma cells and T cells and hijack of mitochondria
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    link.springer.com/article/10.1007/s11060-025-05150-6
  58. link.springer.com link.springer.com
    CLOCK promotes proliferation of glioblastoma cells through acetylating PRPS1/2
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    link.springer.com/article/10.1007/s11060-025-05163-1
  59. 52.53.155.43 52.53.155.43
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  60. www.biorxiv.org www.biorxiv.org
    Cell Settling, Migration, and Stochastic Cancer Expression Suggest Potassium Flux Per H+- Sensitive KCN Members Associated with Oncogenes and Histone/DNA Modulators Potentially Initiates pH-Reversal
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    biorxiv.org/content/10.1101/2025.06.29.662144v2
  61. aacrjournals.org aacrjournals.org
    The DRD2 antagonist haloperidol mediates autophagy-induced ferroptosis to increase temozolomide sensitivity by promoting endoplasmic reticulum stress in glioblastoma
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    aacrjournals.org/clincancerres/article/29/16/3172/728242/The-DRD2-Antagonist-Haloperidol-Mediates-Autophagy
  62. cancerci.biomedcentral.com cancerci.biomedcentral.com
    The GD3 ganglioside promotes cell growth, plasticity and chemotherapy resistance of human glioblastoma cancer stem cells
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    cancerci.biomedcentral.com/articles/10.1186/s12935-025-03790-2
  63. May 2025
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapy-induced senescence of glioblastoma cells is determined by the p21CIP1-CDK1/2 axis and does not require activation of DREAM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12049523/
  65. Apr 2025
  66. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70027
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11955954/
  68. Mar 2025
  69. www.sciencedirect.com www.sciencedirect.com
    PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth
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    sciencedirect.com/science/article/pii/S1097276525001868
  70. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17464
  71. Feb 2025
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel B7-H3 CAR T cells show potent antitumor effects in glioblastoma: a preclinical study
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    pmc.ncbi.nlm.nih.gov/articles/PMC11784176/
  73. 52.53.155.43 52.53.155.43
    Novel Pannexin 1 isoform is increased in cancer
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  74. Jan 2025
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4
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    pmc.ncbi.nlm.nih.gov/articles/PMC11747271/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Involvement of p38 MAPK and MAPKAPK2 in promoting cell death and the inflammatory response to ischemic stress associated with necrotic glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11729867/
  77. Dec 2024
  78. www.nature.com www.nature.com
    Inhibition of thioredoxin reductase 1 sensitizes glucose-starved glioblastoma cells to disulfidptosis
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    nature.com/articles/s41418-024-01440-0
  79. www.sciencedirect.com www.sciencedirect.com
    Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host
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    sciencedirect.com/science/article/pii/S1535610824004471
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mLumiOpto Is a Mitochondrial-Targeted Gene Therapy for Treating Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609628/
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    Neuron-Like Lineage Differentiation Induced by Exogenous Neurexin-1 as a Potential Therapeutic Strategy for Glioma
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    sciencedirect.com/science/article/pii/S0304383524007821
  82. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
  83. Nov 2024
  84. www.sciencedirect.com www.sciencedirect.com
    The cell cycle inhibitor p21CIP1 is essential for irinotecan-induced senescence and plays a decisive role in re-sensitization of temozolomide-resistant glioblastoma cells to irinotecan
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    sciencedirect.com/science/article/pii/S0753332224015208
  85. Oct 2024
  86. www.sciencedirect.com www.sciencedirect.com
    HOXDeRNA activates a cancerous transcription program and super enhancers via genome-wide binding
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    sciencedirect.com/science/article/pii/S1097276524007755
  87. Sep 2024
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Function of a complex of p-Y42 RhoA GTPase and pyruvate kinase M2 in EGF signaling pathway in glioma cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16210
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    Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma
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    sciencedirect.com/science/article/pii/S2666379124004270
  90. Aug 2024
  91. hereditasjournal.biomedcentral.com hereditasjournal.biomedcentral.com
    A potential immunotherapeutic and prognostic biomarker for multiple tumors including glioma: SHOX2
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    hereditasjournal.biomedcentral.com/articles/10.1186/s41065-023-00279-8
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    Comprehensive Analysis of the Clinical and Biological Significances of Endoplasmic Reticulum Stress in Diffuse Gliomas
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    frontiersin.org/articles/10.3389/fcell.2021.619396/full
  93. Jul 2024
  94. www.sciencedirect.com www.sciencedirect.com
    Near-infrared II fluorescence-guided glioblastoma surgery targeting monocarboxylate transporter 4 combined with photothermal therapy
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    sciencedirect.com/science/article/pii/S2352396424002792
  95. Feb 2024
  96. inflammregen.biomedcentral.com inflammregen.biomedcentral.com
    Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation
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    inflammregen.biomedcentral.com/articles/10.1186/s41232-023-00300-7
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    H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
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    sciencedirect.com/science/article/pii/S2211124724000354
  99. link.springer.com link.springer.com
    Migrasomal autophagosomes relieve endoplasmic reticulum stress in glioblastoma cells
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    link.springer.com/article/10.1186/s12915-024-01829-w
  100. Jan 2024
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intranasal Delivery of Oncolytic Adenovirus XVir-N-31 via Optimized Shuttle Cells Significantly Extends Survival of Glioblastoma-Bearing Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10605419/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
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    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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    sciencedirect.com/science/article/pii/S0092867423013478
  104. Dec 2023
  105. www.nature.com www.nature.com
    Jagged1 intracellular domain/SMAD3 complex transcriptionally regulates TWIST1 to drive glioma invasion
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    nature.com/articles/s41419-023-06356-0
  106. 52.53.155.43 52.53.155.43
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  107. Nov 2023
  108. www.sciencedirect.com www.sciencedirect.com
    Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis
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    sciencedirect.com/science/article/pii/S2211124723013517
  109. Oct 2023
  110. inflammregen.biomedcentral.com inflammregen.biomedcentral.com
    Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation
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  111. Sep 2023
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  121. Oct 2022
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  123. Sep 2022
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  131. Jul 2022
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  151. Aug 2021
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  154. Jul 2021
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  157. Jun 2021
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  165. Feb 2021
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  169. Oct 2020
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  171. Sep 2020
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  177. Jan 2020
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  187. Nov 2018
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