145 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor associated neutrophils promote prostate cancer progression by mediating neutrophil trap secretion through PSMA1- NF-κB-HIF-1α signaling axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399615/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398604/
  4. Aug 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12358827/
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    EGFR-STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1-positive prostate cancer
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70069
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer activity of triterpene glycosides from the sea star Solaster pacificus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322260/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
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    Pharmacodynamic analyses of LAT1 inhibitors in vitro and in vivo by targeted metabolomics reveal target-independent effects
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    sciencedirect.com/science/article/pii/S0753332225005967
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AR+TREM2+ macrophage induced pathogenic immunosuppression promotes prostate cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12307935/
  12. Jul 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAF-mediated regulation of prostate cancer stem cell stemness via the Wnt/β-catenin and SDF-1/CXCR4 pathways in castration-resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12303950/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Applying Unbiased, Functional Criteria Allows Selection of Novel Cyclic Peptides for Effective Targeted Drug Delivery to Malignant Prostate Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12298539/
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    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
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    Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors
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    science.org/doi/10.1126/sciadv.adw5228
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260511/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12234718/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and Biosynthesis of Nyuzenamides D and E by Genome Mining in
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  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical Context Shapes the Relationship between Genomic Alterations and Response to AR Inhibitors and Chemotherapy in Metastatic Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12209829/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695179/
  22. Jun 2025
  23. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70049
  24. 52.53.155.43 52.53.155.43
    CTHRC1 promotes bone metastasis in prostate cancer
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    52.53.155.43/f04071ff6077a40bb108a3f03adfcb4d864028a7/Intl Journal of Cancer - 2025 - Sawada - CTHRC1 promotes bone metastasis in prostate cancer-html.html
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    Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22
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  27. pubs.acs.org pubs.acs.org
    Pepticinnamins N, O, and P, Nonribosomal Peptides from the Soil-Derived Streptomyces mirabilis P8-A2
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    pubs.acs.org/doi/full/10.1021/acs.jnatprod.4c00029
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    Downregulation of NONO Suppresses Proliferation, Migration, and Invasion in Metastatic Prostate Cancer
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    onlinelibrary.wiley.com/doi/10.1002/pros.24925
  29. link.springer.com link.springer.com
    Targeted destruction of follicle stimulating hormone receptor-positive cancer cells in vitro and in vivo by a lytic peptide Phor21-FSHβ conjugate
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    link.springer.com/article/10.1186/s10020-025-01292-5
  30. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70073
  31. www.mdpi.com www.mdpi.com
    A Novel Primary Cell Line Model of Localized Prostate Cancer and Radioresistance—A Role for Nicotinamide N-Methyltransferase
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    mdpi.com/2073-4409/14/11/819
  32. May 2025
  33. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  34. elifesciences.org elifesciences.org
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    elifesciences.org/reviewed-preprints/106511
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secreted spermidine synthase reveals a paracrine role for PGC1α-induced growth suppression in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12019391/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11091964/
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    Cytotoxic and anti-migratory effects of Ocimum gratissimum L. essential oil on prostate and cervical cancer cells in vitro
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    sciencedirect.com/science/article/pii/S2667031325000909
  39. Apr 2025
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11870442/
  41. aacrjournals.org aacrjournals.org
    Exploring B7-H4’s Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities
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    aacrjournals.org/mcr/article/23/4/327/754237/Exploring-B7-H4-s-Role-in-Prostate-Cancer-Dormancy
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    Adenosine A3 receptor antagonists as anti-tumor treatment in human prostate cancer: an in vitro study
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.70024
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    Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer
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    sciencedirect.com/science/article/pii/S0925443925000675
  46. Mar 2025
  47. www.sciencedirect.com www.sciencedirect.com
    Increased N-glycosylation of PSMA by GnT-V enhances tumor malignancy through interacting with JAK2 and the subsequent STAT3-mediated transcriptional activation in prostate cancer
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    sciencedirect.com/science/article/pii/S0141813025027904
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secretome Analysis of Prostate Cancer Cell Lines Reveals Cell Cycle-Dependent PSA Secretion and Potential Biomarkers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11899065/
  49. Feb 2025
  50. aacrjournals.org aacrjournals.org
    Preclinical efficacy of a PSMA-targeted actinium-225 conjugate (225Ac-macropa-pelgifatamab) - a targeted alpha therapy for prostate cancer
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    aacrjournals.org/clincancerres/article/30/11/2531/745373/Preclinical-Efficacy-of-a-PSMA-Targeted-Actinium
  51. Jan 2025
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774231/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11771886/
  54. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Clinical significance of stratifying prostate cancer patients through specific circulating genes
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13805
  55. 52.53.155.43 52.53.155.43
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  56. Dec 2024
  57. 52.53.155.43 52.53.155.43
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  58. pubs.acs.org pubs.acs.org
    Encapsulation and Delivery of the Kinase Inhibitor PIK-75 by Organic Core High-Density Lipoprotein-Like Nanoparticles Targeting Scavenger Receptor Class B Type 1
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    pubs.acs.org/doi/10.1021/acsami.4c15472
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining Splicing Factor Requirements for Androgen Receptor Variant Synthesis in Advanced Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612623/
  60. Nov 2024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anoikis in prostate cancer bone metastasis gene signatures and therapeutic implications
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    ncbi.nlm.nih.gov/pmc/articles/PMC11464922/
  62. Oct 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analysis revealing the metabolic landscape of prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11449408/
  64. Sep 2024
  65. www.sciencedirect.com www.sciencedirect.com
    PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
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    sciencedirect.com/science/article/pii/S1476558624000897
  66. Aug 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAS3681, an androgen receptor antagonist, prevents drug resistance driven by aberrant androgen receptor signaling in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306513/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  69. www.sciencedirect.com www.sciencedirect.com
    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    sciencedirect.com/science/article/pii/S2211124724009720
  70. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Assessments of prostate cancer cell functions highlight differences between a pan-PI3K/mTOR inhibitor, gedatolisib, and single-node inhibitors of the PI3K/AKT/mTOR pathway
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13703
  71. Jul 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating miR-6880-5p in extracellular vesicle from plasma as a prognostic biomarker in endocrine therapy-treated castration-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285227/
  73. www.biorxiv.org www.biorxiv.org
    Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
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    biorxiv.org/content/10.1101/2024.07.09.602803v1
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11237870/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identify Regulatory eQTLs by Multiome Sequencing in Prostate Single Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213234/
  76. Jun 2024
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen-responsive FOXP4 is a target for endometrial carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11189448/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The androgen receptor does not directly regulate the transcription of DNA damage response genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022999/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sialic acid blockade inhibits the metastatic spread of prostate cancer to bone
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    ncbi.nlm.nih.gov/pmc/articles/PMC11134892/
  80. Apr 2024
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13653
  82. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERBB3 overexpression is enriched in diverse patient populations with castration-sensitive prostate cancer and is associated with a unique AR activity signature
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016893/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CB307: A Dual Targeting Costimulatory Humabody VH Therapeutic for Treating PSMA-Positive Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016891/
  85. Mar 2024
  86. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  87. www.nature.com www.nature.com
    Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
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    nature.com/articles/s41598-024-57854-w
  88. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Acetylated KHSRP impairs DNA-damage-response-related mRNA decay and facilitates prostate cancer tumorigenesis
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13634
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  90. Feb 2024
  91. 52.53.155.43 52.53.155.43
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13614
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Progressive spreading of DNA methylation in the GSTP1 promoter CpG island across transitions from precursors to invasive prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10529302/
  94. Jan 2024
  95. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13577
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of Extracellular Vesicle-Derived RNA as Potential Prostate Cancer Biomarkers: Role of Cancer-type SLCO1B3 and ABCC3
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    ncbi.nlm.nih.gov/pmc/articles/PMC10777027/
  97. Dec 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10714140/
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  100. Nov 2023
  101. www.sciencedirect.com www.sciencedirect.com
    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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  102. www.sciencedirect.com www.sciencedirect.com
    Prostate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell
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    sciencedirect.com/science/article/pii/S2211124723014365
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent targeting of HDAC and PI3K to overcome phenotypic heterogeneity of castration-resistant and neuroendocrine prostate cancers
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  104. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  105. Oct 2023
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  108. Sep 2023
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  110. Aug 2023
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  114. May 2023
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  120. Mar 2023
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  123. Feb 2023
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  125. Dec 2022
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  129. Aug 2022
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  133. Jul 2022
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  135. May 2022
  136. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  138. Apr 2022
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  141. Mar 2022
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  143. Feb 2022
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  145. Nov 2021
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  147. Sep 2021
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  149. Aug 2021
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  153. Jul 2021
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  155. Jun 2021
  156. cancerres.aacrjournals.org cancerres.aacrjournals.org
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  157. May 2021
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  163. Apr 2021
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  165. Feb 2021
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  168. Jan 2021
  169. www.nature.com www.nature.com
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  170. www.nature.com www.nature.com
    KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer
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  171. www.oncotarget.com www.oncotarget.com
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  172. Nov 2020
  173. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  174. Oct 2020
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  176. Sep 2020
  177. elifesciences.org elifesciences.org
    AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR–CHK2 interaction and prostate cancer survival
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-137-3p Modulates the Progression of Prostate Cancer by Regulating the JNK3/EZH2 Axis
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  184. Jan 2020
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer
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  187. Nov 2017
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    Cellular Migration Ability Is Modulated by Extracellular Purines in Ovarian Carcinoma SKOV‐3 Cells
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