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A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer

1
1. scibot 06 Sep 2025
  
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  ATCC#CCL-229
  
  DOI: 10.1016/j.chembiol.2025.08.004
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2451945625002557
Aug 2025
www.science.org www.science.org

Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer

1
1. scibot 27 Aug 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1126/sciadv.adt1798
  
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science.org/doi/10.1126/sciadv.adt1798
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Systematic screening for functional exon-skipping isoforms using the CRISPR-RfxCas13d system

1
1. scibot 08 Aug 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1016/j.cels.2025.101351
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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cell.com/cell-systems/fulltext/S2405-4712(25)00184-X
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A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers

1
1. scibot 08 Aug 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1016/j.ccell.2025.07.006
  
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sciencedirect.com/science/article/pii/S1535610825003101
Jul 2025
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BDH2 promotes GLIPR1 promoter methylation and thus increases 5-FU sensitivity in colorectal cancer

1
1. scibot 15 Jul 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1016/j.bcp.2025.117153
  
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sciencedirect.com/science/article/pii/S0006295225004186
www.biorxiv.org www.biorxiv.org

Exercise serum promotes DNA damage repair and upregulates DNA repair gene PNKP in colon cancer cells

1
1. scibot 11 Jul 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1101/2025.06.26.659251
  
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biorxiv.org/content/10.1101/2025.06.26.659251v1
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Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models

1
1. scibot 01 Jul 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1101/2025.06.18.660406
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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biorxiv.org/content/10.1101/2025.06.18.660406v1
Jun 2025
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Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22

1
1. scibot 18 Jun 2025
  
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  RRID: CVCL_0399
  
  DOI: 10.1016/j.chembiol.2025.05.012
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2451945625001734
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 12 Jun 2025
  
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  CVCL_0399
  
  DOI: 10.1158/2326-6066.cir-24-0137
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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52.53.155.43/e9fe0912dd31f8e7ff03b2811eb8d2b4310b34d6/PDF-html.html
onlinelibrary.wiley.com onlinelibrary.wiley.com

Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin

1
1. scibot 11 Jun 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1002/ijc.35504
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.35504
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer

1
1. scibot 04 Jun 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1038/s41598-025-03924-6
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12127464/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Palmitic Acid Accumulation Activates Fibroblasts and Promotes Matrix Stiffness in Colorectal Cancer

1
1. scibot 20 May 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1158/0008-5472.CAN-24-2892
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12079102/
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Integrative proteomic profiling of tumor and plasma extracellular vesicles identifies a diagnostic biomarker panel for colorectal cancer

1
1. scibot 16 May 2025
  
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  ATCCCat# CCL-229
  
  DOI: 10.1016/j.xcrm.2025.102090
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S2666379125001636
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OTUD4 inhibits ferroptosis by stabilizing GPX4 and suppressing autophagic degradation to promote tumor progression

1
1. scibot 16 May 2025
  
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  ATCCCAT#CCL-229
  
  DOI: 10.1016/j.celrep.2025.115681
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S2211124725004528
Apr 2025
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The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy

1
1. scibot 19 Apr 2025
  
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  ATCCCCL-229
  
  DOI: 10.1016/j.celrep.2025.115605
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2211124725003766
Mar 2025
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FSTL3 promotes colorectal cancer by activating the HIF1 pathway

1
1. scibot 28 Mar 2025
  
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  RRID: CVCL_0399
  
  DOI: 10.1016/j.gene.2025.149435
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S0378111925002239
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 04 Mar 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1002/1878-0261.70006
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70006
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair

1
1. scibot 19 Feb 2025
  
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  RRID: CVCL_0399
  
  DOI: 10.1158/0008-5472.CAN-24-0397
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11831107/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway

1
1. scibot 16 Jan 2025
  
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  RRID:CVCL_0399
  
  DOI: 10.1158/2767-9764.CRC-24-0471
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695814/
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 05 Jan 2025
  
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  CCL-229
  
  DOI: 10.1016/j.bpj.2024.12.020
  
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  Curator: @sjvitug
  
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52.53.155.43/03201f746b272b94c29dca3b61bdf0551e1c3b6a/PDF-html.html
Dec 2024
www.nature.com www.nature.com

Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state

1
1. scibot 24 Dec 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1038/s41418-024-01439-7
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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nature.com/articles/s41418-024-01439-7
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer

1
1. scibot 21 Dec 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1101/2024.02.20.581056
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11601497/
link.springer.com link.springer.com

Chlorogenic acid suppresses the expression of matrix metalloproteinase-7 and cell invasiveness to almost the same extent as isofraxidin in human colorectal cancer cells

1
1. scibot 21 Dec 2024
  
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  CVCL_0399
  
  DOI: 10.1007/s11626-024-00993-1
  
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link.springer.com/article/10.1007/s11626-024-00993-1
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Longitudinal phosphoproteomics reveals the PI3K-PAK1 axis as a potential target for recurrent colorectal liver metastases

1
1. scibot 17 Dec 2024
  
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  JCRBJCRB9083
  
  DOI: 10.1016/j.celrep.2024.115061
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2211124724014128
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

1
1. scibot 13 Dec 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1177/17588359241303302
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11632859/
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 12 Dec 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1111/febs.17350
  
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  Curator: @scibot
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.17350
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The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression

1
1. scibot 03 Dec 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1038/s41467-024-54920-9
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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nature.com/articles/s41467-024-54920-9
Nov 2024
pubs.acs.org pubs.acs.org

Evaluation of the Combinatory Anticancer Effect of Chemotherapeutic Compounds and Prodigiosin against HCT-116, LoVo, and A549 Cell lines

1
1. scibot 29 Nov 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1021/acsomega.4c04760
  
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pubs.acs.org/doi/10.1021/acsomega.4c04760
Oct 2024
aacrjournals.org aacrjournals.org

2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis

1
1. scibot 02 Oct 2024
  
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  CVCL_0399
  
  DOI: 10.1158/0008-5472.CAN-20-1517
  
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  Curator: @bandrow
  
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aacrjournals.org/cancerres/article/81/2/289/649623/2-Hydroxylation-of-Fatty-Acids-Represses
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Novel immunotherapeutics against LGR5 to target multiple cancer types

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1038/s44321-024-00121-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
www.biorxiv.org www.biorxiv.org

Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

1
1. scibot 15 Sep 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1101/2024.09.05.611458
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @mzhang007
  
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biorxiv.org/content/10.1101/2024.09.05.611458v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis

1
1. scibot 12 Sep 2024
  
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  RRID: CVCL_0399
  
  DOI: 10.1158/0008-5472.CAN-23-2081
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer

1
1. scibot 04 Sep 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1038/s41419-024-06965-3
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11365971/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MMP‐9‐dependent proteolysis of the histone H3 N‐terminal tail: a critical epigenetic step in driving oncogenic transcription and colon tumorigenesis

1
1. scibot 14 Aug 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1002/1878-0261.13652
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11306514/
www.cell.com www.cell.com

Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK

1
1. scibot 13 Aug 2024
  
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  CCL-229
  
  DOI: 10.1016/j.chom.2024.07.001
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(24)00254-3
Jul 2024
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IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma

1
1. scibot 24 Jul 2024
  
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  CVCL_0399
  
  DOI: 10.1016/j.ccell.2024.05.026
  
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Pan-cancer proteogenomics expands the landscape of therapeutic targets

1
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  RRID:CVCL_0399
  
  DOI: 10.1016/j.cell.2024.05.039
  
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Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response

1
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  Cat#CCL-229
  
  DOI: 10.1016/j.celrep.2024.114402
  
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Jun 2024
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Fully automated viability and toxicity screening—A reliable all‐in‐one attempt

1
1. scibot 25 Jun 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1002/cam4.7392
  
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May 2024
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EEF1D stabilized by SRSF9 promotes colorectal cancer via enhancing the proliferation and metastasis

1
1. scibot 30 May 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1002/ijc.35039
  
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PD-1 blockade plus COX inhibitors in dMMR metastatic colorectal cancer: Clinical, genomic, and immunologic analyses from the PCOX trial

1
1. scibot 29 May 2024
  
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  1101HUM-PUMC000164
  
  DOI: 10.1016/j.medj.2024.05.002
  
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Apr 2024
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Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors

1
1. scibot 19 Apr 2024
  
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  RRID: CVCL_0399
  
  DOI: 10.1158/0008-5472.CAN-23-1038
  
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Mar 2024
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Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

1
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  Cat#CCL-229
  
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Reduced chemokine C‐C motif ligand 1 expression may negatively regulate colorectal cancer progression at liver metastatic sites

1
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  DOI: 10.1111/jcmm.18193
  
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Feb 2024
52.53.155.43 52.53.155.43

can-23-1038-html.html

2
1. scibot 23 Feb 2024
  
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  RRID:CVCL_0399
  
  DOI: 10.1158/0008-5472.can-23-1038
  
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Role of oncogenic long noncoding RNA KCNQ1OT1 in colon cancer

1
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  CVCL_0399
  
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A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer

1
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  DOI: 10.1101/2023.12.20.572548
  
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FEBS Press

1
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  DOI: 10.1111/febs.17080
  
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febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.17080
Jan 2024
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The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer

1
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  DOI: 10.1186/s13046-023-02873-0
  
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Dec 2023
52.53.155.43 52.53.155.43

can-23-1038-html.html

1
1. scibot 01 Dec 2023
  
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  RRID: CVCL_0399
  
  DOI: 10.1158/0008-5472.can-23-1038
  
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Sep 2023
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Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer

1
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  RRID:CVCL_0399
  
  DOI: 10.1016/j.isci.2023.107630
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10475482/
Aug 2023
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SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer

1
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  RRID:CVCL_0399
  
  DOI: 10.1016/j.ceca.2021.102384
  
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Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer

1
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  RRID:CVCL_0399
  
  DOI: 10.1158/1535-7163.MCT-23-0110
  
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aacrjournals.org/mct/article/22/8/962/727921/Vincristine-Enhances-the-Efficacy-of-MEK
Jul 2023
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LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3

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  CVCL_0399
  
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Jun 2023
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DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer

1
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  DOI: 10.1158/0008-5472.CAN-22-0370
  
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May 2023
52.53.155.43 52.53.155.43

CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation

1
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  RRID:CVCL_0399
  
  DOI: 10.1002/1878-0261.13438
  
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52.53.155.43/66fe689ddea2ba9b3d8dd8042f1d3395e9a7b944/Molecular Oncology - 2023 - Quandt - CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and-html.html
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MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis

1
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  DOI: 10.1016/j.isci.2023.106770
  
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ALKBH1-mediated m1A demethylation of METTL3 mRNA promotes the metastasis of colorectal cancer by downregulating SMAD7 expression

1
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  RRID:CVCL_0399
  
  DOI: 10.1002/1878-0261.13366
  
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febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13366
Jan 2023
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Optimized Antimicrobial Peptide Jelleine-I Derivative Br-J-I Inhibits Fusobacterium Nucleatum to Suppress Colorectal Cancer Progression

1
1. scibot 19 Jan 2023
  
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  RRID:CVCL_0399
  
  DOI: 10.3390/ijms24021469
  
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52.53.155.43 52.53.155.43

SSRN-id4216993-html.html

1
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  CVCL_0399
  
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52.53.155.43/c64b1ba7641b22fadedc290b96e15ab561ec56db/SSRN-id4216993-html.html
Sep 2022
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Anti-metastatic effects of 1,2,3,4,6-Penta-O-galloyl-β-D-glucose in colorectal cancer: Regulation of cathepsin B-mediated extracellular matrix dynamics and epithelial-to-mesenchymal transition

1
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  DOI: 10.1016/j.phrs.2022.106457
  
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Special issue “The advance of solid tumor research in China”: Discoidin domain receptor 2 promotes colorectal cancer metastasis by regulating epithelial mesenchymal transition via activating AKT signaling

1
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  RRID: CVCL_0399
  
  DOI: 10.1002/ijc.34227
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34227
Aug 2022
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SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis

1
1. scibot 17 Aug 2022
  
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  ATCCCat# CCL-229
  
  DOI: 10.1016/j.celrep.2022.111233
  
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Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of DNA damage

1
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  DOI: 10.1002/ijc.33982
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9314683/
Jul 2022
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Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis

1
1. scibot 27 Jul 2022
  
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  ATCC CCL-229
  
  DOI: 10.1016/j.celrep.2022.111127
  
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Acetylation of p62 regulates base excision repair through interaction with APE1

1
1. scibot 27 Jul 2022
  
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  ATCCCCL-229
  
  DOI: 10.1016/j.celrep.2022.111116
  
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Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth

1
1. scibot 06 Jul 2022
  
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  RRID:CVCL_0399
  
  DOI: 10.1158/0008-5472.CAN-20-4218
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9056178/
Jun 2022
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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis

1
1. scibot 02 Jun 2022
  
  in Public
  
  ATCCCat#CCL-229
  
  DOI: 10.1016/j.celrep.2022.110851
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2211124722006246
May 2022
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The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress

1
1. scibot 11 May 2022
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.7554/eLife.69255
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9064299/
link.springer.com link.springer.com

Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer

1
1. scibot 10 May 2022
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1007/s00018-022-04311-4
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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link.springer.com/article/10.1007/s00018-022-04311-4
Feb 2022
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PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability

1
1. scibot 21 Feb 2022
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1038/s41419-022-04564-8
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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nature.com/articles/s41419-022-04564-8
Jan 2022
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AP-2α Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer

1
1. scibot 05 Jan 2022
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1158/1541-7786.MCR-20-0867
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8254761/
Dec 2021
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Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

1
1. scibot 01 Dec 2021
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1016/j.celrep.2021.110069
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2211124721015552
Oct 2021
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Reprogramming CBX8-PRC1 function with a positive allosteric modulator

1
1. scibot 29 Oct 2021
  
  in Public
  
  CCL-229
  
  DOI: 10.1016/j.chembiol.2021.10.003
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2451945621004372
Sep 2021
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High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment

1
1. scibot 02 Sep 2021
  
  in Public
  
  CCL-229
  
  DOI: 10.1016/j.celrep.2021.109632
  
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sciencedirect.com/science/article/pii/S2211124721010755
Aug 2021
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Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer

1
1. scibot 14 Aug 2021
  
  in Public
  
  CVCL_0399
  
  DOI: 10.3389/fcell.2021.660159
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8355564/
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The Cancer SENESCopedia: A delineation of cancer cell senescence

1
1. scibot 03 Aug 2021
  
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  CVCL_0399
  
  DOI: 10.1016/j.celrep.2021.109441
  
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sciencedirect.com/science/article/pii/S2211124721008585
Jul 2021
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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

1
1. scibot 30 Jul 2021
  
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  LOVO
  
  DOI: 10.1016/j.celrep.2019.08.090
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2211124719311520
elifesciences.org elifesciences.org

Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.7554/eLife.27301
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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elifesciences.org/articles/27301
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Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody

1
1. scibot 27 Jul 2021
  
  in Public
  
  CCL-229
  
  DOI: 10.1016/j.str.2018.10.009
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Therapeutic potential of the phosphino Cu(I) complex (HydroCuP) in the treatment of solid tumors

1
1. scibot 27 Jul 2021
  
  in Public
  
  LoVo
  
  DOI: 10.1038/s41598-017-13698-1
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5655689/
elifesciences.org elifesciences.org

Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:CVCL_039
  
  DOI: 10.7554/eLife.48003
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0399
  
  Curator comments: LoVo Cell Line ATCC Cat# CCL-229
  
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elifesciences.org/articles/48003
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ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

1
1. scibot 22 Jul 2021
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1016/j.xcrm.2021.100350
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S2666379121001993
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Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells

1
1. scibot 14 Jul 2021
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1080/15592294.2020.1789270
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7889220/
May 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer

1
1. scibot 20 May 2021
  
  in Public
  
  RRID: CVCL_0399
  
  DOI: 10.1002/ijc.33561
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33561
Apr 2021
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Integrated Omics of Metastatic Colorectal Cancer

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1016/j.ccell.2020.08.002
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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  RRID:CVCL_0399 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S153561082030413X
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SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer

1
1. scibot 12 Apr 2021
  
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  RRID:CVCL_0399
  
  DOI: 10.1016/j.ceca.2021.102384
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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sciencedirect.com/science/article/pii/S0143416021000385
Mar 2021
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MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis

1
1. scibot 17 Mar 2021
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.3389/fcell.2021.629893
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7959841/
Feb 2021
bmccancer.biomedcentral.com bmccancer.biomedcentral.com

Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1186/s12885-021-07900-x
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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bmccancer.biomedcentral.com/article/10.1186/s12885-021-07900-x
Jan 2021
jeccr.biomedcentral.com jeccr.biomedcentral.com

Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer

1
1. scibot 12 Jan 2021
  
  in Public
  
  CVCL_0399
  
  DOI: 10.1186/s13046-020-01811-8
  
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jeccr.biomedcentral.com/articles/10.1186/s13046-020-01811-8
Oct 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Fluorescent secreted bacterial effectors reveal active intravacuolar proliferation of Listeria monocytogenes in epithelial cells

1
1. scibot 29 Oct 2020
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1371/journal.ppat.1009001
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7580998/
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells

1
1. scibot 26 Sep 2020
  
  in Public
  
  CVCL_0399
  
  DOI: 10.1038/s12276-020-0389-x
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7062870/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1111/bph.14916
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @Naa003
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14916
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Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling

1
1. scibot 04 Sep 2020
  
  in Public
  
  LoVo
  
  DOI: 10.3390/ijms21051773
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @Naa003
  
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  RRID:CVCL_0399 RRIDCUR:Missing
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mdpi.com/1422-0067/21/5/1773
onlinelibrary.wiley.com onlinelibrary.wiley.com

A mutant KRAS‐induced factor REG4 Promotes Cancer Stem Cell Properties via Wnt/β‐catenin Signaling

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1002/ijc.32728
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0399
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32728
link.springer.com link.springer.com

Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1186/s40170-019-0202-2
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @ethanbadger
  
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link.springer.com/article/10.1186/s40170-019-0202-2
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Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P

1
1. scibot 03 Sep 2020
  
  in Public
  
  LoVo
  
  DOI: 10.1016/j.celrep.2020.108049
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0399
  
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  RRID:CVCL_0399 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720310342
Aug 2020
www.nature.com www.nature.com

Zinc-finger antiviral protein acts as a tumor suppressor in colorectal cancer

1
1. scibot 27 Aug 2020
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1038/s41388-020-01416-7
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @evieth
  
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nature.com/articles/s41388-020-01416-7
Jan 2020
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Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.1016/j.chembiol.2019.11.010
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @ethanbadger
  
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  RRID:CVCL_0399 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945619303927
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VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0399
  
  DOI: 10.1016/j.cels.2019.05.009
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @ethanbadger
  
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  RRID:CVCL_0399 RRIDCUR:Validated
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RRID:CVCL_0399

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2405471219301905
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0399
  
  DOI: 10.7554/eLife.40760
  
  Resource: (CLS Cat# 300266/p487_LOVO, RRID:CVCL_0399)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0399
  
  What is this?
  
  RRID:CVCL_0399 RRIDCUR:Validated
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RRID:CVCL_0399

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6374075/
Apr 2019
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TP53 drives invasion through expression of its Δ133p53β variant

1
1. scibot 05 Apr 2019
  
  in Public
  
  CVCL-0399
  
  Curator: @gabimpine
  
  Resource used:
  
  (ATCC Cat# CCL-229, RRID:CVCL_0399)
  
  SciCrunch record: RRID:CVCL-0399
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0399 RRIDCUR:Validated
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RRID:CVCL_0399

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5067115/
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0399
  
  Curator: @evieth
  
  Resource used:
  
  (ATCC Cat# CCL-229, RRID:CVCL_0399)
  
  SciCrunch record: RRID:CVCL_0399
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0399 RRIDCUR:Validated
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RRID:CVCL_0399

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6173768/
www.sciencedirect.com www.sciencedirect.com

Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0399
  
  Resource used:
  
  (ATCC Cat# CCL-229, RRID:CVCL_0399)
  
  SciCrunch record: RRID:CVCL_0399
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0399
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RRID:CVCL_0399

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scibot

URL

sciencedirect.com/science/article/pii/S1931312817303906
www.sciencedirect.com www.sciencedirect.com

A Designed Peptide Targets Two Types of Modifications of p53 with Anti-cancer Activity

1
1. scibot 05 Nov 2018
  
  in Public
  
  CCL-229
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CCL-229, RRID:CVCL_0399)
  
  SciCrunch record: RRID:CVCL_0399
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0399 RRIDCUR:Missing
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RRID:CVCL_0399

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2451945618301120
Nov 2017
www.sciencedirect.com www.sciencedirect.com

CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes

1
1. scibot 08 Nov 2017
  
  in Public
  
  LoVo
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (ATCC Cat# CCL-229, RRID:CVCL_0399)
  
  SciCrunch record: RRID:CVCL_0399
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0399 RRIDCUR:Missing
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RRID:CVCL_0399

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610817301605

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