149 Matching Annotations
  1. Sep 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Notch3 mediated TGF-β1 activation enhances epithelial-mesenchymal transition and cancer stemness in non-small lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12370359/
  3. www.sciencedirect.com www.sciencedirect.com
    HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
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    sciencedirect.com/science/article/pii/S0092867425009298
  4. Aug 2025
  5. www.sciencedirect.com www.sciencedirect.com
    High-dose ascorbic acid selectively induces pyroptosis in LKB1-deficient lung cancer and sensitizes immunotherapy
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    sciencedirect.com/science/article/pii/S2666379125003647
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314509/
  8. Jul 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289886/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12257754/
  11. www.sciencedirect.com www.sciencedirect.com
    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610825002612
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    Combination of growth hormone receptor antagonist and radiation reduces tumour growth in a lung cancer xenograft model
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    sciencedirect.com/org/science/article/pii/S1479681325000147
  13. Jun 2025
  14. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/9a2f79631a0beb40aa09f744c00e5a575573d112/PDF-html.html
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC12129099/
  16. link.springer.com link.springer.com
    SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity
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    link.springer.com/article/10.1007/s12032-025-02771-9
  17. May 2025
  18. www.sciencedirect.com www.sciencedirect.com
    MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725004930
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11091964/
  20. Apr 2025
  21. www.sciencedirect.com www.sciencedirect.com
    Combined inhibition of hexokinase 2 and pyruvate dehydrogenase surmounts SHP2 inhibitor resistance in non-small cell lung cancer with hybrid metabolic state harboring KRAS Q61H mutation
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    sciencedirect.com/science/article/pii/S0925443925002042
  22. 52.53.155.43 52.53.155.43
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    52.53.155.43/4e618aba3cd65bbf93907d966435a11f880c620c/PDF-html.html
  23. www.nature.com www.nature.com
    Tumor cells that resist neutrophil anticancer cytotoxicity acquire a prometastatic and innate immune escape phenotype
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    nature.com/articles/s41423-025-01283-w
  24. Mar 2025
  25. www.sciencedirect.com www.sciencedirect.com
    A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0092867425002910
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11906863/
  27. link.springer.com link.springer.com
    A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer
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    link.springer.com/article/10.1038/s41698-025-00838-4
  28. Feb 2025
  29. translational-medicine.biomedcentral.com translational-medicine.biomedcentral.com
    JMJD6 K375 acetylation restrains lung cancer progression by enhancing METTL14/m6A/SLC3A2 axis mediated cell ferroptosis
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    translational-medicine.biomedcentral.com/articles/10.1186/s12967-025-06241-8
  30. aacrjournals.org aacrjournals.org
    ASCL1 restrains ERK1/2 to promote survival of a subset of neuroendocrine lung cancers
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    aacrjournals.org/mct/article/23/12/1789/750248/ASCL1-Restrains-ERK1-2-to-Promote-Survival-of-a
  31. Dec 2024
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography
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    pmc.ncbi.nlm.nih.gov/articles/PMC11652680/
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Preclinical studies on the antitumor and non-toxic effect of combining pirfenidone with vinorelbine and carboplatin in non-small cell lung cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35276
  34. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  35. www.sciencedirect.com www.sciencedirect.com
    Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates
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    sciencedirect.com/science/article/pii/S2451945624004586
  36. Nov 2024
  37. www.sciencedirect.com www.sciencedirect.com
    PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
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    sciencedirect.com/science/article/pii/S1097276524008682
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532780/
  39. Oct 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984770/
  41. Sep 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand
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    ncbi.nlm.nih.gov/pmc/articles/PMC11416401/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone sialoprotein stimulates cancer cell adhesion through the RGD motif and the αvβ3 and αvβ5 integrin receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413474/
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced pharmacological activities of AKR1C3-activated prodrug AST-3424 in cancer cells with defective DNA repair
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.35170
  45. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  46. Aug 2024
  47. www.sciencedirect.com www.sciencedirect.com
    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
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    sciencedirect.com/science/article/pii/S1074761324003765
  48. www.mdpi.com www.mdpi.com
    A New Renieramycin T Right-Half Analog as a Small Molecule Degrader of STAT3
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    mdpi.com/1660-3397/22/8/370
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  50. Jul 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
  52. www.sciencedirect.com www.sciencedirect.com
    Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0304389424016844
  53. May 2024
  54. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CD74–ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17032
  55. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    sciencedirect.com/science/article/pii/S2666379124002702
  56. www.sciencedirect.com www.sciencedirect.com
    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
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    sciencedirect.com/science/article/pii/S1550413124001384
  57. www.sciencedirect.com www.sciencedirect.com
    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    sciencedirect.com/science/article/pii/S1097276524003241
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078142/
  60. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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    52.53.155.43/761c70660e3a03a822484173742c13c4c44cc6bf/PIIS2589004224010915-html.html
  61. Apr 2024
  62. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    sciencedirect.com/science/article/pii/S2211124724004911
  63. www.mdpi.com www.mdpi.com
    PBMCs as Tool for Identification of Novel Immunotherapy Biomarkers in Lung Cancer
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    mdpi.com/2227-9059/12/4/809
  64. www.sciencedirect.com www.sciencedirect.com
    A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8
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    sciencedirect.com/science/article/pii/S0378111924003305
  65. Mar 2024
  66. www.sciencedirect.com www.sciencedirect.com
    Silibinin is a suppressor of the metastasis-promoting transcription factor ID3
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    sciencedirect.com/science/article/pii/S0944711324001570
  67. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced representative methylome profiling of cell-free DNA for breast cancer detection
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    ncbi.nlm.nih.gov/pmc/articles/PMC10898043/
  70. Feb 2024
  71. www.sciencedirect.com www.sciencedirect.com
    Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer
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    sciencedirect.com/science/article/pii/S2352396424000380
  72. Jan 2024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Griseofulvin Radiosensitizes Non-Small Cell Lung Cancer Cells and Activates cGAS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10073282/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX2 Promotes Radioresistance in Non-small Cell Lung Cancer by Regulating Tumor Cells Dedifferentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10198148/
  75. Dec 2023
  76. www.sciencedirect.com www.sciencedirect.com
    Phosphoprotein dynamics of interacting T cells and tumor cells by HySic
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    sciencedirect.com/science/article/pii/S2211124723016108
  77. Nov 2023
  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  79. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
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    52.53.155.43/fa9809949a94f3d698a02ed4d13d532c010d3e91/British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
  80. Oct 2023
  81. www.sciencedirect.com www.sciencedirect.com
    Lactate activates the mitochondrial electron transport chain independently of its metabolism
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    sciencedirect.com/science/article/pii/S1097276523008006
  82. 52.53.155.43 52.53.155.43
    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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    52.53.155.43/3932de370933c2759897a986a0751f177eee572e/2023.06.15.545148v1.full-html.html
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Ascorbate Elicits Anti-Cancer Activities against Non-Small Cell Lung Cancer through Hydrogen-Peroxide-Induced-DNA-Damage
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    ncbi.nlm.nih.gov/pmc/articles/PMC10525775/
  84. Sep 2023
  85. www.mdpi.com www.mdpi.com
    Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
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    mdpi.com/2076-3921/10/4/534/htm
  86. Aug 2023
  87. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1α
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13508
  88. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Pan-html.html
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    52.53.155.43/0c03bb3198bd7f61266aaeb6cf8a257d677212b0/Molecular Oncology - 2023 - Pan-html.html
  89. 52.53.155.43 52.53.155.43
    The FEBS Journal - 2023 - Chow-html.html
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    52.53.155.43/9b62ca4b0d5353053a17b890e129e282a15ea83a/The FEBS Journal - 2023 - Chow-html.html
  90. www.sciencedirect.com www.sciencedirect.com
    FASN deficiency induces a cytosol-to-mitochondria citrate flux to mitigate detachment-induced oxidative stress
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    sciencedirect.com/science/article/pii/S2211124723009828
  91. Jul 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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    ncbi.nlm.nih.gov/pmc/articles/PMC10354099/
  93. www.nature.com www.nature.com
    E3 ligase MG53 suppresses tumor growth by degrading cyclin D1
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    nature.com/articles/s41392-023-01458-9
  94. Jun 2023
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10267679/
  96. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters
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    pmc.ncbi.nlm.nih.gov/articles/PMC10244369/
  97. May 2023
  98. aacrjournals.org aacrjournals.org
    Decoding the lncRNAome across diverse cellular stresses reveals core p53-effector pan-cancer suppressive lncRNAs
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    aacrjournals.org/cancerrescommun/article/3/5/842/726358/Decoding-the-lncRNAome-Across-Diverse-Cellular
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  100. Mar 2023
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tri-specific killer engager against mesothelin targets NK cells towards lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9992642/
  102. Dec 2022
  103. www.sciencedirect.com www.sciencedirect.com
    EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer
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    sciencedirect.com/science/article/pii/S2211124722017193
  104. Nov 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha
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    sciencedirect.com/science/article/pii/S1097276522010589
  106. Sep 2022
  107. www.jci.org www.jci.org
    Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells
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    jci.org/articles/view/149551
  108. Aug 2022
  109. www.sciencedirect.com www.sciencedirect.com
    Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor
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    sciencedirect.com/science/article/pii/S2589004222011841
  110. 52.53.155.43 52.53.155.43
    149551.1-20220712091612-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased serum levels of KiSS1-derived peptides in non-small cell lung cancer patient liquid biopsies and biological relevance
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    ncbi.nlm.nih.gov/pmc/articles/PMC9359955/
  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cancer-associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications
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  113. Jun 2022
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