172 Matching Annotations
  1. Last 7 days
  2. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202522996
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70206
  4. Mar 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK4 inhibition as a strategy to enhance non-small cell lung cancer radiosensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12353405/
  6. Feb 2026
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    Dual PD-1/IL-2Rα targeting restores CD8+ T cell fitness via STAT5/CD47 axis in SMARCA4-deficient NSCLC
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    sciencedirect.com/science/article/pii/S2666379126000509
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    SQSTM1/p62-mediated PD-L1 biomolecular condensate formation promotes lung tumorigenesis
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    sciencedirect.com/science/article/pii/S2090123226001785
  9. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Synthesis, Activity Evaluation, and Molecular Docking of 3-Quinolin(one)ly-[1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine Derivatives as c-Met Inhibitors
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202501008
  10. Jan 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11
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    pmc.ncbi.nlm.nih.gov/articles/PMC12822425/
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    Basroparib inhibits YAP-driven cancers by stabilizing angiomotin
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70209
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    DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12806248/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12806425/
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    Phenylethanoid Glycosides From Clerodendrum bungei and Their Cytotoxic Activities
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503074
  16. Dec 2025
  17. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Mitochondrial glutamine import sustains electron transport chain integrity independently of glutaminolysis in cancer
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    sciencedirect.com:5037/science/article/pii/S109727652500975X
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    A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698734/
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    A public data-based molecular classification of small cell lung cancer by neuroactive signaling networks unveils distinct microenvironment landscapes and immunotherapy-related prognostic biomarkers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12683401/
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    AMT inhibits the progression of non-small cell lung cancer by suppressing the PI3K/AKT/GSK-3β/β-catenin pathway via H3K27me3 regulation
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    sciencedirect.com:5037/science/article/pii/S0014299925012142
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    SMURF2 facilitates GAP17 Isoform 1 membrane displacement to promote mutant p53-KRAS oncogenic synergy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133423/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12669767/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Monounsaturated Fatty Acid Metabolism for Radiosensitization of KRAS Mutant 3D Lung Cancer Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137014/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666321/
  25. Nov 2025
  26. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy
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    sciencedirect.com:5037/science/article/pii/S0006295225008275
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  28. Oct 2025
  29. www.sciencedirect.com www.sciencedirect.com
    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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    sciencedirect.com/science/article/pii/S2211124725011799
  30. Sep 2025
  31. link.springer.com link.springer.com
    Dammarolic acid improves tyrosine kinase inhibitor activity in lung cancer cells
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    link.springer.com/article/10.1007/s00210-025-04554-5
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Notch3 mediated TGF-β1 activation enhances epithelial-mesenchymal transition and cancer stemness in non-small lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12370359/
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    HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
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    sciencedirect.com/science/article/pii/S0092867425009298
  34. Aug 2025
  35. www.sciencedirect.com www.sciencedirect.com
    High-dose ascorbic acid selectively induces pyroptosis in LKB1-deficient lung cancer and sensitizes immunotherapy
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    sciencedirect.com/science/article/pii/S2666379125003647
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314509/
  38. Jul 2025
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289886/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12257754/
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    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    Combination of growth hormone receptor antagonist and radiation reduces tumour growth in a lung cancer xenograft model
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  43. Jun 2025
  44. 52.53.155.43 52.53.155.43
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    Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
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    SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity
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    link.springer.com/article/10.1007/s12032-025-02771-9
  47. May 2025
  48. www.sciencedirect.com www.sciencedirect.com
    MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725004930
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11091964/
  50. Apr 2025
  51. www.sciencedirect.com www.sciencedirect.com
    Combined inhibition of hexokinase 2 and pyruvate dehydrogenase surmounts SHP2 inhibitor resistance in non-small cell lung cancer with hybrid metabolic state harboring KRAS Q61H mutation
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  53. www.nature.com www.nature.com
    Tumor cells that resist neutrophil anticancer cytotoxicity acquire a prometastatic and innate immune escape phenotype
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    nature.com/articles/s41423-025-01283-w
  54. Mar 2025
  55. www.sciencedirect.com www.sciencedirect.com
    A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0092867425002910
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11906863/
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    A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer
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    link.springer.com/article/10.1038/s41698-025-00838-4
  58. Feb 2025
  59. translational-medicine.biomedcentral.com translational-medicine.biomedcentral.com
    JMJD6 K375 acetylation restrains lung cancer progression by enhancing METTL14/m6A/SLC3A2 axis mediated cell ferroptosis
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    translational-medicine.biomedcentral.com/articles/10.1186/s12967-025-06241-8
  60. aacrjournals.org aacrjournals.org
    ASCL1 restrains ERK1/2 to promote survival of a subset of neuroendocrine lung cancers
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    aacrjournals.org/mct/article/23/12/1789/750248/ASCL1-Restrains-ERK1-2-to-Promote-Survival-of-a
  61. Dec 2024
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography
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  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Preclinical studies on the antitumor and non-toxic effect of combining pirfenidone with vinorelbine and carboplatin in non-small cell lung cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35276
  64. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates
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    sciencedirect.com/science/article/pii/S2451945624004586
  66. Nov 2024
  67. www.sciencedirect.com www.sciencedirect.com
    PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
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  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532780/
  69. Oct 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984770/
  71. Sep 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand
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    ncbi.nlm.nih.gov/pmc/articles/PMC11416401/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone sialoprotein stimulates cancer cell adhesion through the RGD motif and the αvβ3 and αvβ5 integrin receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413474/
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    Enhanced pharmacological activities of AKR1C3-activated prodrug AST-3424 in cancer cells with defective DNA repair
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.35170
  75. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  76. Aug 2024
  77. www.sciencedirect.com www.sciencedirect.com
    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
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    sciencedirect.com/science/article/pii/S1074761324003765
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    A New Renieramycin T Right-Half Analog as a Small Molecule Degrader of STAT3
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  80. Jul 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
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    Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0304389424016844
  83. May 2024
  84. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CD74–ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells
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    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    sciencedirect.com/science/article/pii/S2666379124002702
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    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
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    sciencedirect.com/science/article/pii/S1550413124001384
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078142/
  90. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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  91. Apr 2024
  92. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    sciencedirect.com/science/article/pii/S2211124724004911
  93. www.mdpi.com www.mdpi.com
    PBMCs as Tool for Identification of Novel Immunotherapy Biomarkers in Lung Cancer
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    mdpi.com/2227-9059/12/4/809
  94. www.sciencedirect.com www.sciencedirect.com
    A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8
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    sciencedirect.com/science/article/pii/S0378111924003305
  95. Mar 2024
  96. www.sciencedirect.com www.sciencedirect.com
    Silibinin is a suppressor of the metastasis-promoting transcription factor ID3
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    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced representative methylome profiling of cell-free DNA for breast cancer detection
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    ncbi.nlm.nih.gov/pmc/articles/PMC10898043/
  100. Feb 2024
  101. www.sciencedirect.com www.sciencedirect.com
    Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer
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  102. Jan 2024
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Griseofulvin Radiosensitizes Non-Small Cell Lung Cancer Cells and Activates cGAS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10073282/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX2 Promotes Radioresistance in Non-small Cell Lung Cancer by Regulating Tumor Cells Dedifferentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10198148/
  105. Dec 2023
  106. www.sciencedirect.com www.sciencedirect.com
    Phosphoprotein dynamics of interacting T cells and tumor cells by HySic
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  107. Nov 2023
  108. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  109. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
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    onlinelibrary.wiley.com/doi/10.1002/jcp.26201/full
  223. www.sciencedirect.com www.sciencedirect.com
    LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer
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    sciencedirect.com/science/article/pii/S0092867417315064
  224. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer
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    sciencedirect.com/science/article/pii/S0092867417312448
  225. Nov 2017
  226. www.sciencedirect.com www.sciencedirect.com
    Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer
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    sciencedirect.com/science/article/pii/S0092867417310474
  227. www.sciencedirect.com www.sciencedirect.com
    BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
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    sciencedirect.com/science/article/pii/S1097276517304069
  228. www.sciencedirect.com www.sciencedirect.com
    Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy
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    sciencedirect.com/science/article/pii/S1097276517301983
  229. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5342109/
  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC4959878/