184 Matching Annotations
  1. Last 7 days
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synthesis of 1,2,3-Triazole and Isoxazole Derivatives of [1,2,4]Triazolo[3,4-b][1,3,4]thiadiazine as Potent EGFR Targeting Antilung Cancer Agents
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202502795
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PEGylated liposomal fluopsin C triggers cuproptosis and ferroptosis pathways and suppresses 3D tumor spheroid growth in NCI-H460 cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13086880/
  5. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A covalent molecular glue hijacks the E3 ligase MKRN2 to degrade the ribosomal protein RPS7 and induce synthetic lethality in p53-deficient NSCLC cells
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70434
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Base Editing of TIGIT Reprograms CD155 Signaling in Natural Killer Cells to Enhance Cancer Immunotherapy Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13080321/
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    mTORC1 activity suppresses ferroptosis through a SCARB1-dependent HDL-tocopherol uptake pathway
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    sciencedirect.com/science/article/pii/S1097276526001954
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13072665/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Macropinocytosis and Vascularization Determine Response to mTOR Inhibitors in Lung Squamous Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12774322/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture
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    pmc.ncbi.nlm.nih.gov/articles/PMC13040219/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive Profiling of N 6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042514/
  12. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Cell-cycle-specific lesion evolution rather than inhibition of double-strand-break repair underpins cisplatin radiosensitization
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70240
  13. Mar 2026
  14. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    E2A selectively regulates TGF-β–induced apoptosis in KRAS-mutant non-small cell lung cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70236
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radiation-Enhanced CD24 Membrane Trafficking via GPI Anchoring Mediates Anti-Tumor Immune Evasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012240/
  16. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202522996
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70206
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK4 inhibition as a strategy to enhance non-small cell lung cancer radiosensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12353405/
  19. Feb 2026
  20. www.sciencedirect.com www.sciencedirect.com
    Dual PD-1/IL-2Rα targeting restores CD8+ T cell fitness via STAT5/CD47 axis in SMARCA4-deficient NSCLC
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    sciencedirect.com/science/article/pii/S2666379126000509
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    SQSTM1/p62-mediated PD-L1 biomolecular condensate formation promotes lung tumorigenesis
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    sciencedirect.com/science/article/pii/S2090123226001785
  22. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Synthesis, Activity Evaluation, and Molecular Docking of 3-Quinolin(one)ly-[1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine Derivatives as c-Met Inhibitors
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202501008
  23. Jan 2026
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11
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    pmc.ncbi.nlm.nih.gov/articles/PMC12822425/
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    Basroparib inhibits YAP-driven cancers by stabilizing angiomotin
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70209
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12806248/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression
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    Phenylethanoid Glycosides From Clerodendrum bungei and Their Cytotoxic Activities
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503074
  29. Dec 2025
  30. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Mitochondrial glutamine import sustains electron transport chain integrity independently of glutaminolysis in cancer
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    sciencedirect.com:5037/science/article/pii/S109727652500975X
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698734/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A public data-based molecular classification of small cell lung cancer by neuroactive signaling networks unveils distinct microenvironment landscapes and immunotherapy-related prognostic biomarkers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12683401/
  33. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    AMT inhibits the progression of non-small cell lung cancer by suppressing the PI3K/AKT/GSK-3β/β-catenin pathway via H3K27me3 regulation
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    sciencedirect.com:5037/science/article/pii/S0014299925012142
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMURF2 facilitates GAP17 Isoform 1 membrane displacement to promote mutant p53-KRAS oncogenic synergy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133423/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12669767/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Monounsaturated Fatty Acid Metabolism for Radiosensitization of KRAS Mutant 3D Lung Cancer Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137014/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666321/
  38. Nov 2025
  39. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy
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    sciencedirect.com:5037/science/article/pii/S0006295225008275
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70220
  41. Oct 2025
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    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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    sciencedirect.com/science/article/pii/S2211124725011799
  43. Sep 2025
  44. link.springer.com link.springer.com
    Dammarolic acid improves tyrosine kinase inhibitor activity in lung cancer cells
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    link.springer.com/article/10.1007/s00210-025-04554-5
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Notch3 mediated TGF-β1 activation enhances epithelial-mesenchymal transition and cancer stemness in non-small lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12370359/
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    HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
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    sciencedirect.com/science/article/pii/S0092867425009298
  47. Aug 2025
  48. www.sciencedirect.com www.sciencedirect.com
    High-dose ascorbic acid selectively induces pyroptosis in LKB1-deficient lung cancer and sensitizes immunotherapy
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    sciencedirect.com/science/article/pii/S2666379125003647
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314509/
  51. Jul 2025
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289886/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12257754/
  54. www.sciencedirect.com www.sciencedirect.com
    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610825002612
  55. www.sciencedirect.com www.sciencedirect.com
    Combination of growth hormone receptor antagonist and radiation reduces tumour growth in a lung cancer xenograft model
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    sciencedirect.com/org/science/article/pii/S1479681325000147
  56. Jun 2025
  57. 52.53.155.43 52.53.155.43
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  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC12129099/
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    SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity
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    link.springer.com/article/10.1007/s12032-025-02771-9
  60. May 2025
  61. www.sciencedirect.com www.sciencedirect.com
    MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725004930
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11091964/
  63. Apr 2025
  64. www.sciencedirect.com www.sciencedirect.com
    Combined inhibition of hexokinase 2 and pyruvate dehydrogenase surmounts SHP2 inhibitor resistance in non-small cell lung cancer with hybrid metabolic state harboring KRAS Q61H mutation
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    sciencedirect.com/science/article/pii/S0925443925002042
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  66. www.nature.com www.nature.com
    Tumor cells that resist neutrophil anticancer cytotoxicity acquire a prometastatic and innate immune escape phenotype
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    nature.com/articles/s41423-025-01283-w
  67. Mar 2025
  68. www.sciencedirect.com www.sciencedirect.com
    A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0092867425002910
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11906863/
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    A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer
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    link.springer.com/article/10.1038/s41698-025-00838-4
  71. Feb 2025
  72. translational-medicine.biomedcentral.com translational-medicine.biomedcentral.com
    JMJD6 K375 acetylation restrains lung cancer progression by enhancing METTL14/m6A/SLC3A2 axis mediated cell ferroptosis
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    translational-medicine.biomedcentral.com/articles/10.1186/s12967-025-06241-8
  73. aacrjournals.org aacrjournals.org
    ASCL1 restrains ERK1/2 to promote survival of a subset of neuroendocrine lung cancers
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    aacrjournals.org/mct/article/23/12/1789/750248/ASCL1-Restrains-ERK1-2-to-Promote-Survival-of-a
  74. Dec 2024
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography
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    pmc.ncbi.nlm.nih.gov/articles/PMC11652680/
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Preclinical studies on the antitumor and non-toxic effect of combining pirfenidone with vinorelbine and carboplatin in non-small cell lung cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35276
  77. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
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    Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates
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    sciencedirect.com/science/article/pii/S2451945624004586
  79. Nov 2024
  80. www.sciencedirect.com www.sciencedirect.com
    PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
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    sciencedirect.com/science/article/pii/S1097276524008682
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532780/
  82. Oct 2024
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984770/
  84. Sep 2024
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand
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    ncbi.nlm.nih.gov/pmc/articles/PMC11416401/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone sialoprotein stimulates cancer cell adhesion through the RGD motif and the αvβ3 and αvβ5 integrin receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413474/
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced pharmacological activities of AKR1C3-activated prodrug AST-3424 in cancer cells with defective DNA repair
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.35170
  88. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  89. Aug 2024
  90. www.sciencedirect.com www.sciencedirect.com
    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
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    sciencedirect.com/science/article/pii/S1074761324003765
  91. www.mdpi.com www.mdpi.com
    A New Renieramycin T Right-Half Analog as a Small Molecule Degrader of STAT3
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    mdpi.com/1660-3397/22/8/370
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  93. Jul 2024
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
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    Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0304389424016844
  96. May 2024
  97. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CD74–ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17032
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    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    sciencedirect.com/science/article/pii/S2666379124002702
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    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
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    sciencedirect.com/science/article/pii/S1550413124001384
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    sciencedirect.com/science/article/pii/S1097276524003241
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078142/
  103. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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  225. cancerres.aacrjournals.org cancerres.aacrjournals.org
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  228. Nov 2018
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  238. Nov 2017
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