158 Matching Annotations
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  2. aacrjournals.org aacrjournals.org
    A Novel Anti-CD47 Antibody TJH2201: Efficacious Tumor Suppression with Reduced RBC Toxicity via a SIRPα-Independent Mechanism
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    aacrjournals.org/mct/article/25/1/21/771288/A-Novel-Anti-CD47-Antibody-TJH2201-Efficacious
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    SHR-2005, an FcγR-Dependent CD40 Agonistic Antibody with Potent Antitumor Activities and Favorable Safety Profile
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    aacrjournals.org/mct/article/24/11/1671/766867/SHR-2005-an-Fc-R-Dependent-CD40-Agonistic-Antibody
  4. Apr 2026
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Expression of Glycoprotein B (gB) Correlates With Poor Prognosis in Nasopharyngeal Carcinoma
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    onlinelibrary.wiley.com/doi/full/10.1111/cas.70341
  6. Mar 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nanobody-Engineered CLL-1 CAR-T Cells: Optimizing Tumor-Specific Cytotoxicity and Minimizing Off-Tumor Toxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012018/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T cells Antitumor Immunity Through Metabolic Reprogramming
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    pmc.ncbi.nlm.nih.gov/articles/PMC12990994/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-9 promotes migratory dissemination of malignant T-cells by activating the HIF-1α-Cofilin-1 axis in cutaneous T-cell lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12978574/
  10. Feb 2026
  11. www.sciencedirect.com www.sciencedirect.com
    Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development
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    sciencedirect.com/science/article/pii/S2666379126000352
  12. www.science.org www.science.org
    T cell polarization and NFAT activation are stiffness dependent and differentially regulated by the channels PIEZO1 and ORAI1
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    science.org/doi/10.1126/scisignal.adt9566
  13. Jan 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Potential of the Gut Microbiota and Butyrate to Enhance CAR-T Cell Therapy in Non-Hodgkin Lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12809112/
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    DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling
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    sciencedirect.com/science/article/pii/S2211124725015682
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    IgG2c subclass dominance drives fatal lupus-like nephritis via FcγR and complement activation
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    sciencedirect.com/science/article/pii/S2211124725015475
  17. Dec 2025
  18. www.nature.com www.nature.com
    Engineered antibodies that stabilize drug-modified KRASG12C neoantigens enable selective and potent cross-HLA immunotherapy
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    nature.com/articles/s41467-025-66132-w
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD8+ T cell antitumor immunity via human iNKT-DC conjugates
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    pmc.ncbi.nlm.nih.gov/articles/PMC12716482/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mass Cytometry‐Based Approach for the Investigation of Stimulator of Interferon Genes Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12712875/
  21. Nov 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Use of a Foamy‐Virus Vector System to Produce an ‘Off‐the‐Shelf’ Fcγ‐CR‐T Cell Product for the Treatment of Haematological and Solid Tumour Malignancies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12583232/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eph receptor tyrosine kinases are functional entry receptors for murine gammaherpesvirus 68
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    pmc.ncbi.nlm.nih.gov/articles/PMC12561925/
  24. Oct 2025
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    Integrated Network Pharmacology and Molecular Dynamics Reveal Multi-Target Anticancer Mechanisms of Myrtus communis Essential Oils
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70146
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    A nanobody-based tri-specific NK cell engager targeting CD5 triggers antitumor immunity
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  28. Sep 2025
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    Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens
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    Enhancing Anti-Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression
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  31. Aug 2025
  32. www.nature.com www.nature.com
    A universal monoallelic human leukocyte antigen class II immunopeptidomic platform for defining the immunogenicity potential of therapeutic proteins
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    nature.com/articles/s42003-025-08692-7
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    Bispecific Nanosystems Enable Multieffector Immune Cell Retargeting for Hematologic Malignancy Therapy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202509103
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617988/
  35. Jul 2025
  36. www.sciencedirect.com www.sciencedirect.com
    Spike-specific IgG4 generated post BNT162b2 mRNA vaccination is inhibitory when directly competing with functional IgG subclasses
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  37. academic.oup.com academic.oup.com
    LAG3-MHCII interaction induces a tight cell-cell interface at the immunological synapse
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    academic.oup.com/jimmunol/advance-article/doi/10.1093/jimmun/vkaf120/8175755
  38. www.science.org www.science.org
    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    science.org/doi/10.1126/sciimmunol.adr1105
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eph Receptor Tyrosine Kinases Are Functional Entry Receptors for Murine Gammaherpesvirus 68
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    pmc.ncbi.nlm.nih.gov/articles/PMC12157678/
  41. Jun 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of a Novel Bifunctional Anti-CD47 Fusion Protein with Improved Efficacy and a Favorable Safety Profile
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    pmc.ncbi.nlm.nih.gov/articles/PMC12134747/
  43. May 2025
  44. www.mdpi.com www.mdpi.com
    Low-Dose Salinomycin Alters Mitochondrial Function and Reprograms Global Metabolism in Burkitt Lymphoma
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    mdpi.com/1422-0067/26/11/5125
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    Protocol for assessing antibody-dependent cellular phagocytosis by primary murine and human macrophages
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    sciencedirect.com/science/article/pii/S2666166725001935
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    Nanoparticle-formulated mRNA encoding engineered multivalent SIRPα-Fc fusion proteins shows robust anti-cancer activity in preclinical models
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  49. Apr 2025
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to profile tumor and microenvironment from ovarian cancer patient samples and evaluate cell-based therapy using in vitro killing assays
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  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11955954/
  53. Mar 2025
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037409/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11970383/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11897230/
  57. www.cell.com www.cell.com
    Metabolic engineering to facilitate anti-tumor immunity
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    cell.com/cancer-cell/abstract/S1535-6108(25)00056-X
  58. Feb 2025
  59. www.biorxiv.org www.biorxiv.org
    Spike-specific IgG4 generated post BNT162b2 mRNA vaccination is inhibitory when directly competing with functional IgG subclasses
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    biorxiv.org/content/10.1101/2025.02.12.637095v1
  60. ashpublications.org ashpublications.org
    CD70-specific CAR-NK cells expressing IL-15 for the treatment of CD19-negative B cell malignancy
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    ashpublications.org/bloodadvances/article/8/11/2635/515576/CD70-specific-CAR-NK-cells-expressing-IL-15-for
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    ILT2 and ILT4 drive myeloid suppression via both overlapping and distinct mechanisms
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    aacrjournals.org/cancerimmunolres/article/12/5/592/745126/ILT2-and-ILT4-Drive-Myeloid-Suppression-via-Both
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kaposi’s sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expressing KSHV gB
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  63. www.sciencedirect.com www.sciencedirect.com
    Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes
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  64. Jan 2025
  65. www.sciencedirect.com www.sciencedirect.com
    CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive T cells
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    sciencedirect.com/science/article/pii/S2666379124006608
  66. Dec 2024
  67. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
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  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609632/
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    Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling
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    Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity
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    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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  72. Sep 2024
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    Inhibition of HIV-1 replication by nanobodies targeting tetraspanin CD9
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  74. Aug 2024
  75. www.mdpi.com www.mdpi.com
    NK Cell Degranulation Triggered by Rituximab Identifies Potential Markers of Subpopulations with Enhanced Cytotoxicity toward Malignant B Cells
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  76. Jul 2024
  77. www.sciencedirect.com www.sciencedirect.com
    Protocol for assessing GD2 on formalin-fixed paraffin-embedded tissue sections using immunofluorescence staining
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chidamide represses MYC expression and might improve survival for patients with double expressor lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11236771/
  80. Jun 2024
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    Comparable efficacy of oral bendamustine versus intravenous administration in treating hematologic malignancies
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    link.springer.com/article/10.1007/s00280-024-04688-y
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    A spatiotemporal map of co-receptor signaling networks underlying B cell activation
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  83. May 2024
  84. www.sciencedirect.com www.sciencedirect.com
    Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection
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    Vaccination with nanoparticles displaying gH/gL from Epstein-Barr virus elicits limited cross-protection against rhesus lymphocryptovirus
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    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
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  87. Apr 2024
  88. www.sciencedirect.com www.sciencedirect.com
    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
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  89. Mar 2024
  90. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  91. iubmb.onlinelibrary.wiley.com iubmb.onlinelibrary.wiley.com
    Lactate dehydrogenase A is implicated in the pathogenesis of B-cell lymphoma through regulation of the FER signaling pathway
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    iubmb.onlinelibrary.wiley.com/doi/10.1002/biof.2053
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    Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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  94. Feb 2024
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    An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL
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    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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  97. Jan 2024
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10774422/
  99. Dec 2023
  100. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    sciencedirect.com/science/article/pii/S2211124723015280
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    Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Propylene glycol inactivates respiratory viruses and prevents airborne transmission
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    ncbi.nlm.nih.gov/pmc/articles/PMC10701621/
  103. Nov 2023
  104. www.sciencedirect.com www.sciencedirect.com
    The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions
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    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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  106. www.biorxiv.org www.biorxiv.org
    Kaposi’s sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expressing KSHV gB
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    biorxiv.org/content/10.1101/2023.11.07.566061v1
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    Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
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    link.springer.com/article/10.1186/s12967-023-04669-4
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kaposi’s sarcoma-associated herpesvirus glycoprotein K8.1 is critical for infection in a cell-specific manner and functions at the attachment step on keratinocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10617506/
  109. Oct 2023
  110. www.sciencedirect.com www.sciencedirect.com
    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
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    Enhanced antitumor efficacy, proliferative capacity, and alleviation of T cell exhaustion by fifth-generation chimeric antigen receptor T cells targeting B cell maturation antigen in multiple myeloma
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