152 Matching Annotations
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    Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development
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  3. Feb 2026
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    T cell polarization and NFAT activation are stiffness dependent and differentially regulated by the channels PIEZO1 and ORAI1
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  5. Jan 2026
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    The Potential of the Gut Microbiota and Butyrate to Enhance CAR-T Cell Therapy in Non-Hodgkin Lymphoma
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    DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling
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    IgG2c subclass dominance drives fatal lupus-like nephritis via FcγR and complement activation
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  9. Dec 2025
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    Engineered antibodies that stabilize drug-modified KRASG12C neoantigens enable selective and potent cross-HLA immunotherapy
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    CD8+ T cell antitumor immunity via human iNKT-DC conjugates
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    Mass Cytometry‐Based Approach for the Investigation of Stimulator of Interferon Genes Pathway
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  13. Nov 2025
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    Use of a Foamy‐Virus Vector System to Produce an ‘Off‐the‐Shelf’ Fcγ‐CR‐T Cell Product for the Treatment of Haematological and Solid Tumour Malignancies
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    Eph receptor tyrosine kinases are functional entry receptors for murine gammaherpesvirus 68
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  16. Oct 2025
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    Integrated Network Pharmacology and Molecular Dynamics Reveal Multi-Target Anticancer Mechanisms of Myrtus communis Essential Oils
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    A nanobody-based tri-specific NK cell engager targeting CD5 triggers antitumor immunity
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  20. Sep 2025
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    Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens
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    Enhancing Anti-Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression
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    A universal monoallelic human leukocyte antigen class II immunopeptidomic platform for defining the immunogenicity potential of therapeutic proteins
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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  27. Jul 2025
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    Spike-specific IgG4 generated post BNT162b2 mRNA vaccination is inhibitory when directly competing with functional IgG subclasses
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    LAG3-MHCII interaction induces a tight cell-cell interface at the immunological synapse
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    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    Eph Receptor Tyrosine Kinases Are Functional Entry Receptors for Murine Gammaherpesvirus 68
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  33. Jun 2025
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    Development of a Novel Bifunctional Anti-CD47 Fusion Protein with Improved Efficacy and a Favorable Safety Profile
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  35. May 2025
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    Low-Dose Salinomycin Alters Mitochondrial Function and Reprograms Global Metabolism in Burkitt Lymphoma
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    Protocol for assessing antibody-dependent cellular phagocytosis by primary murine and human macrophages
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    Nanoparticle-formulated mRNA encoding engineered multivalent SIRPα-Fc fusion proteins shows robust anti-cancer activity in preclinical models
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  41. Apr 2025
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    Protocol to profile tumor and microenvironment from ovarian cancer patient samples and evaluate cell-based therapy using in vitro killing assays
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  45. Mar 2025
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  50. Feb 2025
  51. www.biorxiv.org www.biorxiv.org
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  56. Jan 2025
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    CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive T cells
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  58. Dec 2024
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    YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
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    B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors
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  66. Aug 2024
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  72. Jun 2024
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  75. May 2024
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    Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection
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  79. Apr 2024
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    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
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  81. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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  86. Feb 2024
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    An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL
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    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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  89. Jan 2024
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    Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma
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  91. Dec 2023
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis
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    Propylene glycol inactivates respiratory viruses and prevents airborne transmission
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  95. Nov 2023
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    The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions
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    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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  98. www.biorxiv.org www.biorxiv.org
    Kaposi’s sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expressing KSHV gB
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    Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
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    Kaposi’s sarcoma-associated herpesvirus glycoprotein K8.1 is critical for infection in a cell-specific manner and functions at the attachment step on keratinocytes
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  101. Oct 2023
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    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
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    Enhanced antitumor efficacy, proliferative capacity, and alleviation of T cell exhaustion by fifth-generation chimeric antigen receptor T cells targeting B cell maturation antigen in multiple myeloma
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  104. Aug 2023
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    TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
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  106. Jul 2023
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    Preclinical Evidence of an Allogeneic Dual CD20xCD22 CAR to Target a Broad Spectrum of Patients with B-cell Malignancies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10320475/
  108. May 2023
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    ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells
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    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
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  111. Apr 2023
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    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation
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