118 Matching Annotations
  1. Last 7 days
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Driver Mutation Subtypes Differentially Shape Immune Evasion Landscapes in Melanoma: An AI-Driven Inflammatory Pathway Model Implicating CCNE1
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    onlinelibrary.wiley.com/doi/10.1155/humu/6776070
  3. Jun 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing Proteasome Activity in T Cells Alleviates Exhaustion and Improves Antitumor Immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13266348/
  5. Apr 2026
  6. www.biorxiv.org www.biorxiv.org
    SImBA-SiQuAl: a new tool enabling high-content high-throughput phenotypic profiling of 3D microtumours
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    biorxiv.org/content/10.64898/2026.04.14.718366v1
  7. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70224
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    αvβ3 CAR-T Cells Simultaneously Targeting Tumor and Metastases Produce Highly Effective Control in Preclinical Models of Melanoma and Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13041741/
  9. Mar 2026
  10. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226008680-main-html.html
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    54.241.53.176/aa623c97d534dc083ac52ef5d52a1404fcf84e38/1-s2.0-S2589004226008680-main-html.html
  11. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer-Associated Fibroblasts Crosstalk
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202514590
  12. www.sciencedirect.com www.sciencedirect.com
    Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature
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    sciencedirect.com/science/article/pii/S2666379126001114
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Bioinformatics and Wet-Lab-Based Pipeline Identifies CLDN10 and GJB2 as Epigenetically Silenced Tumor Suppressor Genes in Cutaneous Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12986398/
  14. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202520917
  15. Feb 2026
  16. journals.plos.org journals.plos.org
    The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model
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    journals.plos.org/plosbiology/article
  17. Jan 2026
  18. www.biorxiv.org www.biorxiv.org
    NF1 Loss Remodels Tumor Niches for Immune Evasion
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    biorxiv.org/content/10.64898/2026.01.11.698818v1
  19. Dec 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12712269/
  21. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    A BRN2:MYC transcriptional axis regulates interconversion between therapy-resistant and tumorigenic phenotypes in melanoma
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    sciencedirect.com:5037/science/article/pii/S2211124725014470
  22. Nov 2025
  23. www.sciencedirect.com www.sciencedirect.com
    UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression
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    sciencedirect.com/science/article/pii/S1097276525008913
  24. 54.241.53.176 54.241.53.176
    2025.11.06.686987v1.full-html.html
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    54.241.53.176/5f95eab3fd5667f2f2f747297eac3c06fff8097d/2025.11.06.686987v1.full-html.html
  25. Oct 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel Frizzled 7 antibody disrupts the Wnt pathway and inhibits Wilms tumor growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12504202/
  27. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511349
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12629800/
  29. Sep 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12434394/
  31. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Emerging role of ARHGAP29 in melanoma cell phenotype switching
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70114
  32. www.science.org www.science.org
    MAPK and mTORC1 signaling converge to drive cyclin D1 protein production to enable cell cycle reentry in melanoma persister cells
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    science.org/doi/10.1126/scisignal.adw3231
  33. Aug 2025
  34. www.mdpi.com www.mdpi.com
    Assessing Determinants of Response to PARP Inhibition in Germline ATM Mutant Melanoma
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    mdpi.com/1422-0067/26/15/7420
  35. Jun 2025
  36. 52.53.155.43 52.53.155.43
    PDF-html.html
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  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Natural Killer Cell Activation Signature Identifies Cyclin B1/CDK1 as a Druggable Target to Overcome Natural Killer Cell Dysfunction and Tumor Invasiveness in Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12114673/
  38. www.cell.com www.cell.com
    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
  39. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Dose-dependent induction of epithelial-mesenchymal transition in 3D melanoma models by non-thermal plasma treatment
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70055
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic mapping of the human solute carrier superfamily
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130231/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The solute carrier superfamily interactome
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130317/
  42. May 2025
  43. www.sciencedirect.com www.sciencedirect.com
    Stromal lipid species dictate melanoma metastasis and tropism
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    sciencedirect.com/science/article/pii/S1535610825001382
  44. Apr 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11960706/
  46. Mar 2025
  47. www.sciencedirect.com www.sciencedirect.com
    Antagonistic roles for MITF and TFE3 in melanoma plasticity
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    sciencedirect.com/science/article/pii/S2211124725002451
  48. www.sciencedirect.com www.sciencedirect.com
    Protocol for high-precision CRISPR-Cas12a-based SNV detection on synthetic DNA, cell line cfDNA models, and liquid biopsies
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    sciencedirect.com/science/article/pii/S2666166725001029
  49. www.cell.com www.cell.com
    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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    cell.com/cell-metabolism/fulltext/S1550-4131(25)00021-X
  50. Feb 2025
  51. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17423
  52. Jan 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SILAC-based quantification reveals modulation of the immunopeptidome in BRAF and MEK inhibitor sensitive and resistant melanoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11744270/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11711318/
  55. www.sciencedirect.com www.sciencedirect.com
    The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004896
  56. Dec 2024
  57. www.cell.com www.cell.com
    MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity
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    cell.com/cell-reports/abstract/S2211-1247(24)01471-2
  58. www.nature.com www.nature.com
    Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
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    nature.com/articles/s41418-024-01439-7
  59. www.sciencedirect.com www.sciencedirect.com
    Synthetic mismatches enable specific CRISPR-Cas12a-based detection of genome-wide SNVs tracked by ARTEMIS
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    sciencedirect.com/science/article/pii/S2667237524003023
  60. Nov 2024
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive characterization of circulating tumor cells and cell‐free DNA in patients with metastatic melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11547238/
  62. Oct 2024
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35202
  64. Sep 2024
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Splicing control by PHF5A is crucial for melanoma cell survival
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    onlinelibrary.wiley.com/doi/10.1111/cpr.13741
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neddylation signaling inactivation by tetracaine hydrochloride suppresses cell proliferation and alleviates vemurafenib-resistance of melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413085/
  67. Aug 2024
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p300 KAT Regulates SOX10 Stability and Function in Human Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11293458/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  70. Jul 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets
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    ncbi.nlm.nih.gov/pmc/articles/PMC11218003/
  72. Jun 2024
  73. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13672
  74. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13660
  75. May 2024
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11071257/
  77. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  78. Apr 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  80. aacrjournals.org aacrjournals.org
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma
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    aacrjournals.org/cancerres/article/84/3/419/733846/PRMT1-Inhibition-Activates-the-Interferon-Pathway
  81. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PARP1 expression predicts PARP inhibitor sensitivity and correlates with metastatic potential and overall survival in melanoma
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34947
  82. Mar 2024
  83. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  84. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  85. Feb 2024
  86. 52.53.155.43 52.53.155.43
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  87. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  88. Sep 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bioinformatics-based analysis reveals elevated CYTL1 as a potential therapeutic target for BRAF-mutated melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10516578/
  90. Jul 2023
  91. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867423006967
  92. Jun 2023
  93. www.sciencedirect.com www.sciencedirect.com
    Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34+ progenitor cell-derived NK cells
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    sciencedirect.com/science/article/pii/S2589004223011550
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reversing vemurafenib-resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34602
  95. Apr 2023
  96. aacrjournals.org aacrjournals.org
    Discovery of a novel ATP-competitive MEK inhibitor DS03090629 that overcomes resistance conferred by BRAF overexpression in BRAF-mutated melanoma
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    aacrjournals.org/mct/article/22/3/317/718402/Discovery-of-a-Novel-ATP-Competitive-MEK-Inhibitor
  97. Feb 2023
  98. www.sciencedirect.com www.sciencedirect.com
    An adverse tumor-protective effect of IDO1 inhibition
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    sciencedirect.com/science/article/pii/S2666379123000332
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
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    ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
  100. Jan 2023
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437570/
  102. Nov 2022
  103. www.sciencedirect.com www.sciencedirect.com
    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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    sciencedirect.com/science/article/pii/S2211124722014668
  104. Aug 2022
  105. 52.53.155.43 52.53.155.43
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  106. link.springer.com link.springer.com
    VEGF-A promotes the motility of human melanoma cells through the VEGFR1–PI3K/Akt signaling pathway
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    link.springer.com/article/10.1007/s11626-022-00717-3
  107. www.sciencedirect.com www.sciencedirect.com
    AP-1 transcription factor network explains diverse patterns of cellular plasticity in melanoma cells
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    sciencedirect.com/science/article/pii/S2211124722009561
  108. Jul 2022
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9321645/
  110. Jun 2022
  111. www.sciencedirect.com www.sciencedirect.com
    Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
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    sciencedirect.com/science/article/pii/S2211124722007811
  112. May 2022
  113. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  114. Apr 2022
  115. www.sciencedirect.com www.sciencedirect.com
    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
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    sciencedirect.com/science/article/pii/S221112472200393X
  116. Feb 2022
  117. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4
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    sciencedirect.com/science/article/pii/S2451945622000496
  118. Jan 2022
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC8285950/
  120. Oct 2021
  121. www.sciencedirect.com www.sciencedirect.com
    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124721013371
  122. Sep 2021
  123. www.sciencedirect.com www.sciencedirect.com
    Oncogene-dependent sloppiness in mRNA translation
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    sciencedirect.com/science/article/pii/S109727652100736X
  124. www.sciencedirect.com www.sciencedirect.com
    Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation
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    sciencedirect.com/science/article/pii/S1534580721006778
  125. Aug 2021
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic Modeling of a Novel Oncolytic Virus, V937, to Describe Viral Kinetic and Dynamic Processes Following Intratumoral and Intravenous Administration
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