111 Matching Annotations
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    Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature
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    sciencedirect.com/science/article/pii/S2666379126001114
  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Bioinformatics and Wet-Lab-Based Pipeline Identifies CLDN10 and GJB2 as Epigenetically Silenced Tumor Suppressor Genes in Cutaneous Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12986398/
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    Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202520917
  6. Feb 2026
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    The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model
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    journals.plos.org/plosbiology/article
  8. Jan 2026
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    NF1 Loss Remodels Tumor Niches for Immune Evasion
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    biorxiv.org/content/10.64898/2026.01.11.698818v1
  10. Dec 2025
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    Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin
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    A BRN2:MYC transcriptional axis regulates interconversion between therapy-resistant and tumorigenic phenotypes in melanoma
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    sciencedirect.com:5037/science/article/pii/S2211124725014470
  13. Nov 2025
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    UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression
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  16. Oct 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel Frizzled 7 antibody disrupts the Wnt pathway and inhibits Wilms tumor growth
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    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis
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  20. Sep 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors
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    Emerging role of ARHGAP29 in melanoma cell phenotype switching
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  23. www.science.org www.science.org
    MAPK and mTORC1 signaling converge to drive cyclin D1 protein production to enable cell cycle reentry in melanoma persister cells
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    science.org/doi/10.1126/scisignal.adw3231
  24. Aug 2025
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    Assessing Determinants of Response to PARP Inhibition in Germline ATM Mutant Melanoma
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  26. Jun 2025
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  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Natural Killer Cell Activation Signature Identifies Cyclin B1/CDK1 as a Druggable Target to Overcome Natural Killer Cell Dysfunction and Tumor Invasiveness in Melanoma
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    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
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    Dose-dependent induction of epithelial-mesenchymal transition in 3D melanoma models by non-thermal plasma treatment
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    Metabolic mapping of the human solute carrier superfamily
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    The solute carrier superfamily interactome
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  33. May 2025
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    Stromal lipid species dictate melanoma metastasis and tropism
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  35. Apr 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11960706/
  37. Mar 2025
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    Antagonistic roles for MITF and TFE3 in melanoma plasticity
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    Protocol for high-precision CRISPR-Cas12a-based SNV detection on synthetic DNA, cell line cfDNA models, and liquid biopsies
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    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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  41. Feb 2025
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  43. Jan 2025
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    SILAC-based quantification reveals modulation of the immunopeptidome in BRAF and MEK inhibitor sensitive and resistant melanoma cells
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  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity
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    The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
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  47. Dec 2024
  48. www.cell.com www.cell.com
    MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity
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    Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
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    Synthetic mismatches enable specific CRISPR-Cas12a-based detection of genome-wide SNVs tracked by ARTEMIS
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  51. Nov 2024
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive characterization of circulating tumor cells and cell‐free DNA in patients with metastatic melanoma
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  53. Oct 2024
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism
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  55. Sep 2024
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    Splicing control by PHF5A is crucial for melanoma cell survival
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neddylation signaling inactivation by tetracaine hydrochloride suppresses cell proliferation and alleviates vemurafenib-resistance of melanoma
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  58. Aug 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p300 KAT Regulates SOX10 Stability and Function in Human Melanoma
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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  61. Jul 2024
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    Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets
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  63. Jun 2024
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  66. May 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma
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    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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  69. Apr 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  71. aacrjournals.org aacrjournals.org
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma
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    aacrjournals.org/cancerres/article/84/3/419/733846/PRMT1-Inhibition-Activates-the-Interferon-Pathway
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    PARP1 expression predicts PARP inhibitor sensitivity and correlates with metastatic potential and overall survival in melanoma
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  73. Mar 2024
  74. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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  76. Feb 2024
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    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  79. Sep 2023
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    Bioinformatics-based analysis reveals elevated CYTL1 as a potential therapeutic target for BRAF-mutated melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10516578/
  81. Jul 2023
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    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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  83. Jun 2023
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    Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34+ progenitor cell-derived NK cells
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    sciencedirect.com/science/article/pii/S2589004223011550
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    Reversing vemurafenib-resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34602
  86. Apr 2023
  87. aacrjournals.org aacrjournals.org
    Discovery of a novel ATP-competitive MEK inhibitor DS03090629 that overcomes resistance conferred by BRAF overexpression in BRAF-mutated melanoma
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    aacrjournals.org/mct/article/22/3/317/718402/Discovery-of-a-Novel-ATP-Competitive-MEK-Inhibitor
  88. Feb 2023
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    An adverse tumor-protective effect of IDO1 inhibition
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
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    ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
  91. Jan 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437570/
  93. Nov 2022
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    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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  95. Aug 2022
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    VEGF-A promotes the motility of human melanoma cells through the VEGFR1–PI3K/Akt signaling pathway
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    link.springer.com/article/10.1007/s11626-022-00717-3
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    AP-1 transcription factor network explains diverse patterns of cellular plasticity in melanoma cells
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  99. Jul 2022
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9321645/
  101. Jun 2022
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    Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
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  103. May 2022
  104. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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  105. Apr 2022
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    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
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  107. Feb 2022
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    Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4
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  109. Jan 2022
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC8285950/
  111. Oct 2021
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    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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  113. Sep 2021
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    Oncogene-dependent sloppiness in mRNA translation
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    Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation
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    sciencedirect.com/science/article/pii/S1534580721006778
  116. Aug 2021
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic Modeling of a Novel Oncolytic Virus, V937, to Describe Viral Kinetic and Dynamic Processes Following Intratumoral and Intravenous Administration
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    ncbi.nlm.nih.gov/pmc/articles/PMC8343024/
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    Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies
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    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
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  120. Jul 2021
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    Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo
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    Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses
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    Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32756
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    Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
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  125. May 2021
  126. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Targeting pan-ETS factors inhibits melanoma progression
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    cancerres.aacrjournals.org/content/81/8/2071
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    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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  132. Feb 2021
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  136. Dec 2020
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  138. Oct 2020
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  140. Sep 2020
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  144. Aug 2020
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  146. Jan 2020
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  151. Nov 2018
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  155. Nov 2017
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