108 Matching Annotations
  1. Feb 2026
  2. journals.plos.org journals.plos.org
    The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model
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    journals.plos.org/plosbiology/article
  3. Jan 2026
  4. www.biorxiv.org www.biorxiv.org
    NF1 Loss Remodels Tumor Niches for Immune Evasion
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    biorxiv.org/content/10.64898/2026.01.11.698818v1
  5. Dec 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12712269/
  7. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    A BRN2:MYC transcriptional axis regulates interconversion between therapy-resistant and tumorigenic phenotypes in melanoma
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    sciencedirect.com:5037/science/article/pii/S2211124725014470
  8. Nov 2025
  9. www.sciencedirect.com www.sciencedirect.com
    UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression
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    sciencedirect.com/science/article/pii/S1097276525008913
  10. 54.241.53.176 54.241.53.176
    2025.11.06.686987v1.full-html.html
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    54.241.53.176/5f95eab3fd5667f2f2f747297eac3c06fff8097d/2025.11.06.686987v1.full-html.html
  11. Oct 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel Frizzled 7 antibody disrupts the Wnt pathway and inhibits Wilms tumor growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12504202/
  13. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511349
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12629800/
  15. Sep 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12434394/
  17. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Emerging role of ARHGAP29 in melanoma cell phenotype switching
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70114
  18. www.science.org www.science.org
    MAPK and mTORC1 signaling converge to drive cyclin D1 protein production to enable cell cycle reentry in melanoma persister cells
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    science.org/doi/10.1126/scisignal.adw3231
  19. Aug 2025
  20. www.mdpi.com www.mdpi.com
    Assessing Determinants of Response to PARP Inhibition in Germline ATM Mutant Melanoma
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    mdpi.com/1422-0067/26/15/7420
  21. Jun 2025
  22. 52.53.155.43 52.53.155.43
    PDF-html.html
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  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Natural Killer Cell Activation Signature Identifies Cyclin B1/CDK1 as a Druggable Target to Overcome Natural Killer Cell Dysfunction and Tumor Invasiveness in Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12114673/
  24. www.cell.com www.cell.com
    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
  25. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Dose-dependent induction of epithelial-mesenchymal transition in 3D melanoma models by non-thermal plasma treatment
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70055
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic mapping of the human solute carrier superfamily
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130231/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The solute carrier superfamily interactome
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130317/
  28. May 2025
  29. www.sciencedirect.com www.sciencedirect.com
    Stromal lipid species dictate melanoma metastasis and tropism
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    sciencedirect.com/science/article/pii/S1535610825001382
  30. Apr 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11960706/
  32. Mar 2025
  33. www.sciencedirect.com www.sciencedirect.com
    Antagonistic roles for MITF and TFE3 in melanoma plasticity
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    sciencedirect.com/science/article/pii/S2211124725002451
  34. www.sciencedirect.com www.sciencedirect.com
    Protocol for high-precision CRISPR-Cas12a-based SNV detection on synthetic DNA, cell line cfDNA models, and liquid biopsies
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    sciencedirect.com/science/article/pii/S2666166725001029
  35. www.cell.com www.cell.com
    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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    cell.com/cell-metabolism/fulltext/S1550-4131(25)00021-X
  36. Feb 2025
  37. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17423
  38. Jan 2025
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SILAC-based quantification reveals modulation of the immunopeptidome in BRAF and MEK inhibitor sensitive and resistant melanoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11744270/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11711318/
  41. www.sciencedirect.com www.sciencedirect.com
    The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004896
  42. Dec 2024
  43. www.cell.com www.cell.com
    MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity
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    cell.com/cell-reports/abstract/S2211-1247(24)01471-2
  44. www.nature.com www.nature.com
    Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
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    nature.com/articles/s41418-024-01439-7
  45. www.sciencedirect.com www.sciencedirect.com
    Synthetic mismatches enable specific CRISPR-Cas12a-based detection of genome-wide SNVs tracked by ARTEMIS
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    sciencedirect.com/science/article/pii/S2667237524003023
  46. Nov 2024
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive characterization of circulating tumor cells and cell‐free DNA in patients with metastatic melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11547238/
  48. Oct 2024
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35202
  50. Sep 2024
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Splicing control by PHF5A is crucial for melanoma cell survival
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    onlinelibrary.wiley.com/doi/10.1111/cpr.13741
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neddylation signaling inactivation by tetracaine hydrochloride suppresses cell proliferation and alleviates vemurafenib-resistance of melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413085/
  53. Aug 2024
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p300 KAT Regulates SOX10 Stability and Function in Human Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11293458/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  56. Jul 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets
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    ncbi.nlm.nih.gov/pmc/articles/PMC11218003/
  58. Jun 2024
  59. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13672
  60. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13660
  61. May 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11071257/
  63. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  64. Apr 2024
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  66. aacrjournals.org aacrjournals.org
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma
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    aacrjournals.org/cancerres/article/84/3/419/733846/PRMT1-Inhibition-Activates-the-Interferon-Pathway
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PARP1 expression predicts PARP inhibitor sensitivity and correlates with metastatic potential and overall survival in melanoma
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34947
  68. Mar 2024
  69. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  70. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  71. Feb 2024
  72. 52.53.155.43 52.53.155.43
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    52.53.155.43/9ee9b923ebb85a391d8ef40b8ed2af8f0d12ae03/419-html.html
  73. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  74. Sep 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bioinformatics-based analysis reveals elevated CYTL1 as a potential therapeutic target for BRAF-mutated melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10516578/
  76. Jul 2023
  77. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867423006967
  78. Jun 2023
  79. www.sciencedirect.com www.sciencedirect.com
    Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34+ progenitor cell-derived NK cells
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    sciencedirect.com/science/article/pii/S2589004223011550
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reversing vemurafenib-resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34602
  81. Apr 2023
  82. aacrjournals.org aacrjournals.org
    Discovery of a novel ATP-competitive MEK inhibitor DS03090629 that overcomes resistance conferred by BRAF overexpression in BRAF-mutated melanoma
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    aacrjournals.org/mct/article/22/3/317/718402/Discovery-of-a-Novel-ATP-Competitive-MEK-Inhibitor
  83. Feb 2023
  84. www.sciencedirect.com www.sciencedirect.com
    An adverse tumor-protective effect of IDO1 inhibition
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    sciencedirect.com/science/article/pii/S2666379123000332
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
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    ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
  86. Jan 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437570/
  88. Nov 2022
  89. www.sciencedirect.com www.sciencedirect.com
    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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    sciencedirect.com/science/article/pii/S2211124722014668
  90. Aug 2022
  91. 52.53.155.43 52.53.155.43
    cd-21-1671-html.html
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    52.53.155.43/5e67ddaf80a7b90ec85c4b24452e48b76eabacbf/cd-21-1671-html.html
  92. link.springer.com link.springer.com
    VEGF-A promotes the motility of human melanoma cells through the VEGFR1–PI3K/Akt signaling pathway
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    link.springer.com/article/10.1007/s11626-022-00717-3
  93. www.sciencedirect.com www.sciencedirect.com
    AP-1 transcription factor network explains diverse patterns of cellular plasticity in melanoma cells
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    sciencedirect.com/science/article/pii/S2211124722009561
  94. Jul 2022
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9321645/
  96. Jun 2022
  97. www.sciencedirect.com www.sciencedirect.com
    Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
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    sciencedirect.com/science/article/pii/S2211124722007811
  98. May 2022
  99. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  100. Apr 2022
  101. www.sciencedirect.com www.sciencedirect.com
    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
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    sciencedirect.com/science/article/pii/S221112472200393X
  102. Feb 2022
  103. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4
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    sciencedirect.com/science/article/pii/S2451945622000496
  104. Jan 2022
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC8285950/
  106. Oct 2021
  107. www.sciencedirect.com www.sciencedirect.com
    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124721013371
  108. Sep 2021
  109. www.sciencedirect.com www.sciencedirect.com
    Oncogene-dependent sloppiness in mRNA translation
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    sciencedirect.com/science/article/pii/S109727652100736X
  110. www.sciencedirect.com www.sciencedirect.com
    Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation
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    sciencedirect.com/science/article/pii/S1534580721006778
  111. Aug 2021
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic Modeling of a Novel Oncolytic Virus, V937, to Describe Viral Kinetic and Dynamic Processes Following Intratumoral and Intravenous Administration
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    ncbi.nlm.nih.gov/pmc/articles/PMC8343024/
  113. www.sciencedirect.com www.sciencedirect.com
    Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies
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    sciencedirect.com/science/article/pii/S153458072100592X
  114. www.sciencedirect.com www.sciencedirect.com
    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
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    sciencedirect.com/science/article/pii/S0092867419306774
  115. Jul 2021
  116. www.sciencedirect.com www.sciencedirect.com
    Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo
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    sciencedirect.com/science/article/pii/S1534580719300140
  117. www.sciencedirect.com www.sciencedirect.com
    Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses
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    sciencedirect.com/science/article/pii/S2211124719311866
  118. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32756
  119. www.sciencedirect.com www.sciencedirect.com
    Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
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    sciencedirect.com/science/article/pii/S2211124719310009
  120. May 2021
  121. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Targeting pan-ETS factors inhibits melanoma progression
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    cancerres.aacrjournals.org/content/81/8/2071
  122. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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    sciencedirect.com/science/article/pii/S0092867421004955
  123. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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    sciencedirect.com/science/article/pii/S1550413121001108
  124. Apr 2021
  125. www.sciencedirect.com www.sciencedirect.com
    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
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    sciencedirect.com/science/article/pii/S1097276521000988
  126. www.sciencedirect.com www.sciencedirect.com
    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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    sciencedirect.com/science/article/pii/S1097276521001775
  127. Feb 2021
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma
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  131. Dec 2020
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  133. Oct 2020
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    Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells
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  135. Sep 2020
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    The effects of 20-kDa human placental GH in male and female GH deficient mice: an improved human GH?
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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  139. Aug 2020
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    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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  141. Jan 2020
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    Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
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    Intermittent Versus Continuous Dosing of MAPK Inhibitors in the Treatment of BRAF-Mutated Melanoma
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  144. www.cell.com www.cell.com
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    Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo
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  146. Nov 2018
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    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
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    Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
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  150. Nov 2017
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    A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product
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