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HNRNPC stabilizes m6A-modified AC145207.5 to accelerate tumorigenesis in colorectal cancer by impeding the Nrf2/GPX4 axis-mediated ferroptosis

1
1. scibot 08 Apr 2025
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.ncrna.2025.04.002
  
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sciencedirect.com/science/article/pii/S2468054025000411
Mar 2025
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SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response

1
1. scibot 29 Mar 2025
  
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  ATCCCat#CCL-228
  
  DOI: 10.1016/j.celrep.2025.115434
  
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sciencedirect.com/science/article/pii/S2211124725002050
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

1
1. scibot 27 Mar 2025
  
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  RRID:CVCL_0546
  
  DOI: 10.7554/eLife.101973
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11932694/
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 26 Mar 2025
  
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  RRID:CVCL_0546
  
  DOI: 10.1101/2025.03.14.642985
  
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52.53.155.43/59f01b99c7b267c6741834ba4d27823473c7d4e7/PDF-html.html
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WBP1 regulates mitochondrial function and ferroptosis to modulate chemoresistance in colorectal cancer

1
1. scibot 13 Mar 2025
  
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  RRID: CVCL_0546
  
  DOI: 10.1186/s10020-025-01151-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11900258/
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Blocking WNT7A Enhances MHC-I Antigen Presentation and Enhances the Effectiveness of Immune Checkpoint Blockade Therapy

1
1. scibot 06 Mar 2025
  
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  RRID: CVCL_0546
  
  DOI: 10.1158/2326-6066.CIR-24-0484
  
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aacrjournals.org/cancerimmunolres/article/13/3/400/752015/Blocking-WNT7A-Enhances-MHC-I-Antigen-Presentation
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Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells

1
1. scibot 04 Mar 2025
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.immuni.2025.02.007
  
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sciencedirect.com/science/article/pii/S107476132500072X
Feb 2025
www.preprints.org www.preprints.org

Parecoxib and 5-Fluorouracil Synergistic Inhibition of Metastasis of Colorectal Cancer Cells by Targeting Akt/NF-κB and EMT Pathways

1
1. scibot 27 Feb 2025
  
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  RRID: CVCL_0546
  
  DOI: 10.20944/preprints202405.1890.v1
  
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preprints.org/manuscript/202405.1890/v1
52.53.155.43 52.53.155.43

618530-html.html

1
1. scibot 27 Feb 2025
  
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  RRID: CVCL_0546
  
  DOI: 10.1038/s41598-021-92623-z
  
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52.53.155.43/d987b315610b1f43a42ec7b2f935f8d3991ad50c/Maunscript_BJP_20230110-html.html
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Potentiating anti-tumor immunity by re-engaging immune synapse molecules

1
1. scibot 25 Feb 2025
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.xcrm.2025.101975
  
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sciencedirect.com/science/article/pii/S2666379125000485
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The integrative genomic and functional immunological analyses of colorectal cancer initiating cells to modulate stemness properties and the susceptibility to immune responses

1
1. scibot 20 Feb 2025
  
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  CVCL_0546
  
  DOI: 10.1186/s12967-025-06176-0
  
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link.springer.com/article/10.1186/s12967-025-06176-0
52.53.155.43 52.53.155.43

cir-24-0484-html.html

1
1. scibot 20 Feb 2025
  
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  CVCL_0546
  
  DOI: 10.1158/2326-6066.CIR-24-0484
  
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52.53.155.43/907147dca7b0350ae4d97a7f04ddc5ad1538a91e/cir-24-0484-html.html
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Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer

1
1. scibot 13 Feb 2025
  
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  CVCL_0546
  
  DOI: 10.1158/0008-5472.CAN-23-3987
  
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aacrjournals.org/cancerres/article/84/20/3371/749080/Cancer-Associated-Fibroblasts-Expressing-Sulfatase
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway

1
1. scibot 16 Jan 2025
  
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  RRID: CVCL_0546
  
  DOI: 10.1158/2767-9764.CRC-24-0471
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695814/
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Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation

1
1. scibot 07 Jan 2025
  
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  CVCL_0546
  
  DOI: 10.1016/j.immuni.2024.12.004
  
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sciencedirect.com/science/article/pii/S1074761324005685
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Unraveling the mechanism of microRNA-134 in colon cancer progression: targeting KRAS and PIK3CA for cell cycle control and histone deacetylase regulation.

1
1. scibot 03 Jan 2025
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.yexcr.2024.114385
  
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sciencedirect.com/science/article/pii/S0014482724004762
Dec 2024
www.researchsquare.com www.researchsquare.com

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1
1. scibot 27 Dec 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.21203/rs.3.rs-1885484/v1
  
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researchsquare.com/article/rs-5544620/v1
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AMIGO2 characterizes cancer‐associated fibroblasts in metastatic colon cancer and induces the release of paracrine active tumorigenic secretomes

1
1. scibot 21 Dec 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1002/path.6363
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11638658/
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Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

1
1. scibot 13 Dec 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1177/17588359241303302
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11632859/
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Epigenetic Suppression of miR-137 Induces RNF4 Expression, Facilitating Wnt Signaling in Colorectal Cancer

1
1. scibot 13 Dec 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1002/mc.23859
  
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onlinelibrary.wiley.com/doi/full/10.1002/mc.23859
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LncRNA DANCR-V1 is a novel regulator of Wnt/β-catenin and TGF-β1/SMAD signaling pathways in colorectal cancer: an in vitro and in silico study

1
1. scibot 12 Dec 2024
  
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  RRID:CCL-228
  
  DOI: 10.1007/s11033-024-10128-0
  
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link.springer.com/article/10.1007/s11033-024-10128-0
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ADAM17 promotes colorectal cancer migration and invasion by regulating the TGF-β/Smad signaling pathway

1
1. scibot 05 Dec 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.tice.2024.102648
  
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sciencedirect.com/science/article/pii/S0040816624003495
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The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression

1
1. scibot 03 Dec 2024
  
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  CVCL_0546
  
  DOI: 10.1038/s41467-024-54920-9
  
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nature.com/articles/s41467-024-54920-9
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lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing

1
1. scibot 02 Dec 2024
  
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  RRID: CVCL_0546
  
  DOI: 10.1016/j.molcel.2024.10.036
  
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sciencedirect.com/science/article/pii/S1097276524008761
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B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies

1
1. scibot 02 Dec 2024
  
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  CVCL_0546
  
  DOI: 10.1016/j.ebiom.2024.105459
  
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sciencedirect.com/science/article/pii/S235239642400495X
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Histone-acetyl epigenome regulates TGF-β pathway-associated chemoresistance in colorectal cancer

1
1. scibot 26 Nov 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.tranon.2024.102166
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11585898/
52.53.155.43 52.53.155.43

mcr-24-0433-html.html

1
1. scibot 14 Nov 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1158/1541-7786.mcr-24-0433
  
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52.53.155.43/62727082158815ce6c72e771121628c409f356be/mcr-24-0433-html.html
Oct 2024
aacrjournals.org aacrjournals.org

2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis

1
1. scibot 02 Oct 2024
  
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  RRID: CVCL_0546
  
  DOI: 10.1158/0008-5472.CAN-20-1517
  
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aacrjournals.org/cancerres/article/81/2/289/649623/2-Hydroxylation-of-Fatty-Acids-Represses
Sep 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

CT45A1-mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell-in-cell structure, potentiating the progression of microsatellite instability-high colorectal cancer

1
1. scibot 27 Sep 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1002/1878-0261.13736
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13736
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Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer

1
1. scibot 25 Sep 2024
  
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  Cat#CCL-228
  
  DOI: 10.1016/j.molcel.2024.08.035
  
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sciencedirect.com/science/article/pii/S1097276524007317
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Novel immunotherapeutics against LGR5 to target multiple cancer types

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1038/s44321-024-00121-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
www.biorxiv.org www.biorxiv.org

Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

1
1. scibot 15 Sep 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1101/2024.09.05.611458
  
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biorxiv.org/content/10.1101/2024.09.05.611458v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis

1
1. scibot 12 Sep 2024
  
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  RRID: CVCL_0546
  
  DOI: 10.1158/0008-5472.CAN-23-2081
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression

1
1. scibot 12 Sep 2024
  
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  RRID:CVCL_0546
  
  DOI: 10.1158/0008-5472.CAN-23-1878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372369/
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RNA interacts with topoisomerase I to adjust DNA topology

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Jianpi Jiedu Recipe Inhibits Proliferation through Reactive Oxygen Species-Induced Incomplete Autophagy and Reduces PD-L1 Expression in Colon Cancer

1
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The SW480 cell line as a model of resident and migrating colon cancer stem cells

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BPS Publications

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BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism

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Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation

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Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer

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The Natural Alkaloid (-)- N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex

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Identification of specific susceptibility loci for the early-onset colorectal cancer

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Activation of miR-500a-3p/CDK6 axis suppresses aerobic glycolysis and colorectal cancer progression

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Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer

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Parecoxib and 5-Fluorouracil Synergistically Inhibit EMT and Subsequent Metastasis in Colorectal Cancer by Targeting PI3K/Akt/NF-κB Signaling

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Identification and structural characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3

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AXIN2 promotes degradation of AXIN1 through tankyrase in colorectal cancer cells

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Interactions between genistein and Wnt pathway in colon adenocarcinoma and early embryos

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RAS/RAF co-mutation and ERBB2 copy number modulates HER2 heterogeneity and responsiveness to HER2-directed therapy in colorectal cancer

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The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells

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Bacterial indole-3-lactic acid affects epithelium–macrophage crosstalk to regulate intestinal homeostasis

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Disrupting the interaction between a p53 gain-of-function mutant and the transcriptional co-activator PC4 reverses drug resistance in cancer cells

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Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

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Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

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Eosinophils exhibit a unique transcriptional signature and increased sensitivity to IL-3-induced activation in response to colorectal cancer cells

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KRAS silencing impacts chromatin organization and transcriptional activity in colorectal cancer cells

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An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth

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Role of oncogenic long noncoding RNA KCNQ1OT1 in colon cancer

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The Oncosuppressive Properties of KCTD1: Its Role in Cell Growth and Mobility

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Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3

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FEBS Press

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The non-vesicle cell-free DNA (cfDNA) induces cell transformation associated with horizontal DNA transfer

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Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling

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Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells

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The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer

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Phosphoprotein dynamics of interacting T cells and tumor cells by HySic

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Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies

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Transcript CD81-215 may be a long noncoding RNA of stromal origin with tumor-promoting role in colon cancer

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TCOF1 promotes the colorectal cancer progression by stabilizing β-catenin

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p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation

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Deficiency of BCAT2-mediated branched-chain amino acid catabolism promotes colorectal cancer development

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The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis

1
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Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis

1
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Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer

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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype

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Flat clathrin lattices are linked to metastatic potential in colorectal cancer

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The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis

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GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer

1
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E3 ligase MG53 suppresses tumor growth by degrading cyclin D1

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618530-html.html

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Jun 2023
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DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer

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May 2023
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Anti-proliferation and induction of mitochondria-mediated apoptosis by Garcinia hanburyi resin in colorectal cancer cells

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MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis

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Nanofitins targeting heat shock protein 110: an innovative immunotherapeutic modality in cancer.

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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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APC-driven actin nucleation powers collective cell dynamics in colorectal cancer cells

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Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis

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An integrated multi-omics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-Fluorouracil

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Mar 2023
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GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer

1
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Overexpression of synaptic vesicle protein Rab GTPase 3C promotes vesicular exocytosis and drug resistance in colorectal cancer cells

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BPS Publications

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Feb 2023
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NIR-II fluorescence imaging-guided colorectal cancer surgery targeting CEACAM5 by a nanobody

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Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer

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ALKBH1-mediated m1A demethylation of METTL3 mRNA promotes the metastasis of colorectal cancer by downregulating SMAD7 expression

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Dec 2022
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Increased replication origin firing links replication stress to whole chromosomal instability in human cancer

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Inhibition of insulin‐like growth factor 2 mRNA‐binding protein 1 sensitizes colorectal cancer cells to chemotherapeutics

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Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells

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Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer

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Expression of NMU, PPBP and GNG4 in colon cancer and their influences on prognosis

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5-Methylcytosine (m5C) modification in peripheral blood immune cells is a novel non-invasive biomarker for colorectal cancer diagnosis

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RhoB affects colitis through modulating cell signaling and intestinal microbiome

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  DOI: 10.1186/s40168-022-01347-3
  
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Special issue “The advance of solid tumor research in China”: Discoidin domain receptor 2 promotes colorectal cancer metastasis by regulating epithelial mesenchymal transition via activating AKT signaling

1
1. scibot 14 Sep 2022
  
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  RRID: CVCL_0546
  
  DOI: 10.1002/ijc.34227
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34227
Jul 2022
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Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis

1
1. scibot 27 Jul 2022
  
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  ATCC CCL-228
  
  DOI: 10.1016/j.celrep.2022.111127
  
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Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness

1
1. scibot 27 Jul 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.isci.2022.104721
  
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Tumor cell conditioned media drives collagen remodeling via fibroblast and pericyte activation in an in vitro premetastatic niche model

1
1. scibot 08 Jul 2022
  
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  ATCCCCL-228
  
  DOI: 10.1016/j.isci.2022.104645
  
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Jun 2022
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RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells

1
1. scibot 10 Jun 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.xcrm.2022.100655
  
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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis

1
1. scibot 02 Jun 2022
  
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  ATCCCat#CCL-228
  
  DOI: 10.1016/j.celrep.2022.110851
  
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May 2022
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The Taspase1/Myosin1f-axis regulates filopodia dynamics

1
1. scibot 19 May 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.isci.2022.104355
  
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JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation

1
1. scibot 13 May 2022
  
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  ATCCCCL-228
  
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FILIP1L loss is a driver of aggressive mucinous colorectal adenocarcinoma and mediates cytokinesis defects through PFDN1

1
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  RRID:CVCL_0546
  
  DOI: 10.1158/0008-5472.CAN-21-0897
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8563430/
Apr 2022
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Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization

1
1. scibot 29 Apr 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.devcel.2022.04.010
  
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Canonical Wnt Signaling Induces Focal Adhesion and Integrin Beta-1 Endocytosis

1
1. scibot 09 Apr 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.isci.2022.104123
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8987407/
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Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

1
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  ATCCCCL-228
  
  DOI: 10.1016/j.celrep.2022.110641
  
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Small-molecule NSC59984 induces mutant p53 degradation through a ROS-ERK2-MDM2 axis in cancer cells

1
1. scibot 05 Apr 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1158/1541-7786.MCR-21-0149
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8983457/
Mar 2022
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Neddylation is essential for β-catenin degradation in Wnt signaling pathway

1
1. scibot 23 Mar 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.celrep.2022.110538
  
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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

1
1. scibot 16 Mar 2022
  
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  ATCCCCL-228
  
  DOI: 10.1016/j.celrep.2022.110511
  
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CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

1
1. scibot 09 Mar 2022
  
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  Walter Bodmer's laboratory, University of OxfordCCL-228
  
  DOI: 10.1016/j.celrep.2022.110493
  
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Cancer-associated fibroblasts at the unfavorable desmoplastic stroma promote colorectal cancer aggressiveness: potential role of ADAM9

1
1. scibot 02 Mar 2022
  
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  CVCL_0546
  
  DOI: 10.1002/ijc.33947
  
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Recruitment of DNA to tumor-derived microvesicles

1
1. scibot 02 Mar 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.celrep.2022.110443
  
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Feb 2022
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PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability

1
1. scibot 21 Feb 2022
  
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  RRID: CVCL_0546
  
  DOI: 10.1038/s41419-022-04564-8
  
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nature.com/articles/s41419-022-04564-8
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Hypermethylation of miR-145 promoter-mediated SOX9-CLDN8 pathway regulates intestinal mucosal barrier in Crohn's disease

2
1. scibot 11 Feb 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.ebiom.2022.103846
  
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  DOI: 10.1016/j.ebiom.2022.103846
  
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Tanshinone IIA induces autophagy in colon cancer cells through MEK/ERK/mTOR pathway

1
1. scibot 04 Feb 2022
  
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  RRID:CVCL_0546
  
  DOI: 10.21037/tcr-20-1963
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8797932/
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Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2

1
1. scibot 02 Feb 2022
  
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  ATCCCat#CCL-228
  
  DOI: 10.1016/j.celrep.2022.110319
  
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Jan 2022
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NEBL and AKT1 maybe new targets to eliminate the colorectal cancer cells resistance to oncolytic effect of vesicular stomatitis virus M-protein

1
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  DOI: 10.1016/j.omto.2021.11.013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8666707/
Dec 2021
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USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1

1
1. scibot 29 Dec 2021
  
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  CCL-228
  
  DOI: 10.1016/j.celrep.2021.110174
  
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MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma

1
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  DOI: 10.1016/j.neo.2021.12.003
  
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Glutamine deprivation triggers NAGK-dependent hexosamine salvage

1
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  RRID:CVCL_0546
  
  DOI: 10.7554/eLife.62644
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
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Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells

1
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  RRID:CVCL_0546
  
  DOI: 10.1158/0008-5472.CAN-20-3371
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8178204/
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Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

1
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.celrep.2021.110069
  
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Nov 2021
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A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer

1
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.bioorg.2021.105505
  
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febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
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  CCL-228
  
  DOI: 10.1111/febs.16261
  
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Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

1
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  DOI: 10.1016/j.ebiom.2021.103646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
Oct 2021
cancerci.biomedcentral.com cancerci.biomedcentral.com

Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC

1
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  RRID:CVCL_0546
  
  DOI: 10.1186/s12935-021-02221-2
  
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cancerci.biomedcentral.com/articles/10.1186/s12935-021-02221-2
academic.oup.com academic.oup.com

Pituitary somatotroph adenoma-derived exosomes: characterization of nonhormonal actions

1
1. scibot 01 Oct 2021
  
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  RRID:CVCL_0546
  
  DOI: 10.1210/clinem/dgab651
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab651/6360746
Aug 2021
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YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models

1
1. scibot 31 Aug 2021
  
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  RRID:CVCL_0546
  
  DOI: 10.1007/s13402-021-00630-z
  
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A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

1
1. scibot 15 Aug 2021
  
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  CVCL_0546
  
  DOI: 10.7554/eLife.70429
  
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Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer

1
1. scibot 14 Aug 2021
  
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TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer

1
1. scibot 14 Aug 2021
  
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Untitled document

1
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Untitled document

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  DOI: 10.1002/jcp.27359
  
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Untitled document

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Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization

1
1. scibot 06 Aug 2021
  
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Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

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  DOI: 10.1038/s41467-021-24687-4
  
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Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

1
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Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis

1
1. scibot 31 Jul 2021
  
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  Human colorectal adenocarcinoma SW480 cells (male)
  
  DOI: 10.1016/j.molcel.2019.10.015
  
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Oncotarget | Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone

1
1. scibot 30 Jul 2021
  
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  SW480
  
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BPS Publications

1
1. scibot 29 Jul 2021
  
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  DOI: 10.1111/bph.14863
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14863
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Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization

1
1. scibot 29 Jul 2021
  
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ANKLE1 N6‐Methyladenosine‐related variant is associated with colorectal cancer risk by maintaining the genomic stability

1
1. scibot 29 Jul 2021
  
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  DOI: 10.1002/ijc.32677
  
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Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

1
1. scibot 29 Jul 2021
  
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  DOI: 10.1016/j.ccell.2019.05.013
  
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Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

1
1. scibot 29 Jul 2021
  
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  Colon: SW480
  
  DOI: 10.1016/j.celrep.2019.07.084
  
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Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis

1
1. scibot 28 Jul 2021
  
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  SW480
  
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TP53 drives invasion through expression of its Δ133p53β variant

1
1. scibot 27 Jul 2021
  
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  CVCL-0546
  
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Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2

1
1. scibot 27 Jul 2021
  
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  CCL-228
  
  DOI: 10.1016/j.chembiol.2018.10.009
  
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Untitled document

1
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  DOI: 10.1016/j.ebiom.2018.09.052
  
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Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells

1
1. scibot 09 Jul 2021
  
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  CCL-228
  
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sciencedirect.com/science/article/pii/S2211124721006872
Jun 2021
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Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

1
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  DOI: 10.7554/eLife.61461
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8192123/
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KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

1
1. scibot 17 Jun 2021
  
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Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis

1
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  DOI: 10.1016/j.canlet.2021.05.033
  
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May 2021
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BPS Publications

1
1. scibot 10 May 2021
  
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  CVCL_0546
  
  DOI: 10.1111/bph.15422
  
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BPS Publications

1
1. scibot 10 May 2021
  
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  RRID:CVCL_0546
  
  DOI: 10.1111/bph.15372
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15372
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Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability

1
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  CCL-228
  
  DOI: 10.1016/j.devcel.2020.11.012
  
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Genome‐Wide Estrogen Receptor β Chromatin Binding in Human Colon Cancer Cells Reveals its Tumor Suppressor Activity

1
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  DOI: 10.1002/ijc.33573
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33573
Apr 2021
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Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling

2
1. scibot 28 Apr 2021
  
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  CVCL_0546
  
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Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer

1
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  CCL-228
  
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Estrogen Receptor Beta Influences the Inflammatory p65 Cistrome in Colon Cancer Cells

1
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  DOI: 10.3389/fendo.2021.650625
  
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SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer

1
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  DOI: 10.1016/j.ceca.2021.102384
  
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Jan 2021
jeccr.biomedcentral.com jeccr.biomedcentral.com

Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer

1
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  DOI: 10.1186/s13046-020-01811-8
  
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jeccr.biomedcentral.com/articles/10.1186/s13046-020-01811-8
Dec 2020
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Long Non-Coding RNA LINC00239 Functions as a Competitive Endogenous RNA by Sponging microRNA-484 and Enhancing KLF12 Expression to Promote the Oncogenicity of Colorectal Cancer

1
1. scibot 07 Dec 2020
  
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Gracillin shows potent efficacy against colorectal cancer through inhibiting the STAT3 pathway

1
1. scibot 07 Dec 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.1111/jcmm.16134
  
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onlinelibrary.wiley.com/doi/full/10.1111/jcmm.16134
Nov 2020
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FEBS Press

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  RRID:CVCL_0546
  
  DOI: 10.1002/1878-0261.12821
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12821
Oct 2020
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Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

1
1. scibot 21 Oct 2020
  
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  DOI: 10.7554/eLife.61960
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7556867/
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Protocol for Probing Regulated Lysosomal Activity and Function in Living Cells

1
1. scibot 21 Oct 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.xpro.2020.100132
  
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sciencedirect.com/science/article/pii/S2666166720301192
Sep 2020
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The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in A Zebrafish Xenograft Colon Cancer Model

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1. scibot 26 Sep 2020
  
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  DOI: 10.3390/cancers12040853
  
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mdpi.com/2072-6694/12/4/853
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GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery

1
1. scibot 25 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107973
  
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sciencedirect.com/science/article/pii/S2211124720309542
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Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq)

1
1. scibot 15 Sep 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.ebiom.2020.102868
  
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PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis

1
1. scibot 11 Sep 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.7554/eLife.52135
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7299340/
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A mutant KRAS‐induced factor REG4 Promotes Cancer Stem Cell Properties via Wnt/β‐catenin Signaling

1
1. scibot 09 Sep 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.1002/ijc.32728
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32728
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Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer

1
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.devcel.2020.01.034
  
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New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells

1
1. scibot 04 Sep 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.1038/s12276-020-0389-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7062870/
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Melatonin sensitises shikonin-induced cancer cell death mediated by oxidative stress via inhibition of the SIRT3/SOD2-AKT pathway

1
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.redox.2020.101632
  
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sciencedirect.com/science/article/pii/S2213231720308375
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Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness

1
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  RRID: CVCL_0546
  
  DOI: 10.1002/ijc.32955
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32955
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Single-Cell Transcriptome Analysis of Colon Cancer Cell Response to 5-Fluorouracil-Induced DNA Damage

1
1. scibot 03 Sep 2020
  
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  SW480
  
  DOI: 10.1016/j.celrep.2020.108077
  
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sciencedirect.com/science/article/pii/S2211124720310627
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Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P

1
1. scibot 03 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108049
  
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sciencedirect.com/science/article/pii/S2211124720310342
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 03 Sep 2020
  
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  CVCL_0546
  
  DOI: 10.1002/1878-0261.12600
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12600
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Cotargeting BET proteins overcomes resistance arising from PI3K/mTOR blockade‐induced protumorigenic senescence in colorectal cancer

1
1. scibot 03 Sep 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.1002/ijc.33047
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33047
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BPS Publications

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1. scibot 03 Sep 2020
  
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  CVCL_0546
  
  DOI: 10.1111/bph.14981
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14981
Aug 2020
cancerres.aacrjournals.org cancerres.aacrjournals.org

CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer

1
1. scibot 14 Aug 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.1158/0008-5472.CAN-19-1161
  
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cancerres.aacrjournals.org/content/80/2/334
Jan 2020
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PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia

1
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.molcel.2019.09.018
  
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sciencedirect.com/science/article/pii/S1097276519307233
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Long non‐coding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cells

1
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  RRID:CVCL_0546
  
  DOI: 10.1002/ijc.32608
  
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onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32608
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Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth

1
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.chembiol.2019.06.005
  
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sciencedirect.com/science/article/pii/S2451945619302065
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Distinct Binding Preferences between Ras and Raf Family Members and the Impact on Oncogenic Ras Signaling

1
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.molcel.2019.09.004
  
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TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer

1
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.ebiom.2019.06.046
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6642315/
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:CVCL_0546
  
  DOI: 10.1016/j.chembiol.2018.11.013
  
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sciencedirect.com/science/article/pii/S2451945618304355
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Untitled document

1
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  DOI: 10.7554/eLife.43333
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6435321/

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