248 Matching Annotations
  1. Last 7 days
  2. 54.241.53.176 54.241.53.176
    v17p0074-html.html
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    54.241.53.176/8b9956b61e4c394898a91badcad7d30fb55ef47f/v17p0074-html.html
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Citrate Synthase Splice Variant Rewires the TCA Cycle to Promote Colorectal Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616247/
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    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    sciencedirect.com/science/article/pii/S2211383525007452
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    CDC7 stabilized by KRAS signaling reactivation impairs chemosensitivity in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S1043661825004529
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cytoplasmic HMGB1 promotes and interacts with BECN1 through ZNF460 to induce autophagy and accelerate radioresistance in colorectal cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12558843/
  8. Oct 2025
  9. www.sciencedirect.com www.sciencedirect.com
    The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells
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    sciencedirect.com/science/article/pii/S1097276525008226
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    Purinergic Ecto-Enzyme CD73 is a Context-Dependent Tumor Suppressor in Colorectal Cancer
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    sciencedirect.com/science/article/pii/S0021925825027164
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    Hotspot mutant p53-R273H enhances mitochondrial biogenesis and cell migration in primary colorectal cancer in response to oxaliplatin
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    sciencedirect.com/science/article/pii/S0167488925001788
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    CANDiT: A machine learning framework for differentiation therapy in colorectal cancer
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    sciencedirect.com/science/article/pii/S266637912500494X
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    Phase separation of circCHD6-encoded 216aa protein promotes colorectal cancer metastasis
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    sciencedirect.com/science/article/pii/S0141813025089792
  14. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A synthetic benzoxazine dimer derivative targets c-Myc to inhibit colorectal cancer progression
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70127
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    Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties
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    sciencedirect.com/science/article/pii/S2666379125004847
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Role of NOL3 in Colon Adenocarcinoma Metastasis and Its Association With DNA Methylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12488313/
  17. Sep 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring the Anticancer Properties of 4-Phenylthiazole-Based Ru(II) and Os(II) Metallacycles Featuring 1-Methylimidazole as N-Donor Functionality
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    pmc.ncbi.nlm.nih.gov/articles/PMC12463534/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12434394/
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    Knockdown of translocon-associated protein subunit beta (TRAPβ) stimulates cell cycle arrest and apoptosis in human colorectal cancer cells
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    sciencedirect.com/science/article/pii/S0167488925001624
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    A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer
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    sciencedirect.com/science/article/pii/S2451945625002557
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt10b signaling regulates replication stress–induced chromosomal instability in human cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12373720/
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    SLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124725009106
  24. Aug 2025
  25. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Lifespan-Regulated CAR-Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202417677
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    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcript PHF19-207 May Be a Long Non-Coding RNA with Tumor-Promoting Role in Colon Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12292646/
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    Combined MEK and PARP inhibition enhances radiation response in rectal cancer
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    sciencedirect.com/science/article/pii/S266637912500357X
  29. www.cell.com www.cell.com
    Systematic screening for functional exon-skipping isoforms using the CRISPR-RfxCas13d system
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    cell.com/cell-systems/fulltext/S2405-4712(25)00184-X
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314522/
  31. Jul 2025
  32. www.biorxiv.org www.biorxiv.org
    Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early-Onset Colorectal Cancer
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    biorxiv.org/content/10.1101/2025.07.15.664829v1
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260813/
  34. www.biorxiv.org www.biorxiv.org
    Salmonella hijacks a host glucose transporter for intravacuolar proliferation
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    biorxiv.org/content/10.1101/2025.06.10.658782v1
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12239510/
  36. Jun 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Itaconate and obesity-related hormones promote tumor progression – new insights on metabolic dysfunction in early-onset colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12183228/
  38. www.sciencedirect.com www.sciencedirect.com
    Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22
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    sciencedirect.com/science/article/pii/S2451945625001734
  39. elifesciences.org elifesciences.org
    BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus
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    elifesciences.org/articles/100497
  40. May 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Palmitic Acid Accumulation Activates Fibroblasts and Promotes Matrix Stiffness in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079102/
  42. www.mdpi.com www.mdpi.com
    Expression of Prooncogenic Nuclear Receptor 4A (NR4A)-Regulated Genes β1-Integrin and G9a Inhibited by Dual NR4A1/2 Ligands
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    Novel Approaches to 3D Cancer Heterospheroid Culture and Assay Development for Immunotherapy Screening
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    sciencedirect.com/science/article/pii/S0014482725002009
  44. link.springer.com link.springer.com
    Differential unfolded protein response regulation in KRAS silencing sensitive and innately resistant colorectal cancer cells
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    link.springer.com/article/10.1038/s41598-025-94549-2
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    Integrative proteomic profiling of tumor and plasma extracellular vesicles identifies a diagnostic biomarker panel for colorectal cancer
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  46. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    The E3 Ligase NEDD4L Prevents Colorectal Cancer Liver Metastasis via Degradation of PRMT5 to Inhibit the AKT/mTOR Signaling Pathway
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202504704
  47. Apr 2025
  48. www.sciencedirect.com www.sciencedirect.com
    ARID3A inhibits colorectal cancer cell stemness and drug-resistance by targeting a multitude of stemness-associated genes
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    sciencedirect.com/science/article/pii/S0024320525002772
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    A new EGFR and c-Met bispecific NIR-II fluorescent probe for visualising colorectal cancer and metastatic lymph nodes
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    sciencedirect.com/science/article/pii/S2352396425001318
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    Yi Gong San inhibits tumor immune escape by sensitizing colorectal cancer stem cells via the NF-κB pathway
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    link.springer.com/article/10.1186/s41065-025-00412-9
  51. www.sciencedirect.com www.sciencedirect.com
    HNRNPC stabilizes m6A-modified AC145207.5 to accelerate tumorigenesis in colorectal cancer by impeding the Nrf2/GPX4 axis-mediated ferroptosis
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    sciencedirect.com/science/article/pii/S2468054025000411
  52. Mar 2025
  53. www.sciencedirect.com www.sciencedirect.com
    SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response
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    sciencedirect.com/science/article/pii/S2211124725002050
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11932694/
  55. 52.53.155.43 52.53.155.43
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  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    WBP1 regulates mitochondrial function and ferroptosis to modulate chemoresistance in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11900258/
  57. aacrjournals.org aacrjournals.org
    Blocking WNT7A Enhances MHC-I Antigen Presentation and Enhances the Effectiveness of Immune Checkpoint Blockade Therapy
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    aacrjournals.org/cancerimmunolres/article/13/3/400/752015/Blocking-WNT7A-Enhances-MHC-I-Antigen-Presentation
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    Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells
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    sciencedirect.com/science/article/pii/S107476132500072X
  59. Feb 2025
  60. www.preprints.org www.preprints.org
    Parecoxib and 5-Fluorouracil Synergistic Inhibition of Metastasis of Colorectal Cancer Cells by Targeting Akt/NF-κB and EMT Pathways
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    preprints.org/manuscript/202405.1890/v1
  61. 52.53.155.43 52.53.155.43
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    Potentiating anti-tumor immunity by re-engaging immune synapse molecules
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    sciencedirect.com/science/article/pii/S2666379125000485
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    The integrative genomic and functional immunological analyses of colorectal cancer initiating cells to modulate stemness properties and the susceptibility to immune responses
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    link.springer.com/article/10.1186/s12967-025-06176-0
  64. 52.53.155.43 52.53.155.43
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  65. aacrjournals.org aacrjournals.org
    Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer
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    aacrjournals.org/cancerres/article/84/20/3371/749080/Cancer-Associated-Fibroblasts-Expressing-Sulfatase
  66. Jan 2025
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695814/
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    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    Unraveling the mechanism of microRNA-134 in colon cancer progression: targeting KRAS and PIK3CA for cell cycle control and histone deacetylase regulation.
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    sciencedirect.com/science/article/pii/S0014482724004762
  70. Dec 2024
  71. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/article/rs-7072571/'https://www.researchsquare.com/article/rs-7072571/v1
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AMIGO2 characterizes cancer‐associated fibroblasts in metastatic colon cancer and induces the release of paracrine active tumorigenic secretomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11638658/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11632859/
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epigenetic Suppression of miR-137 Induces RNF4 Expression, Facilitating Wnt Signaling in Colorectal Cancer
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23859
  75. link.springer.com link.springer.com
    LncRNA DANCR-V1 is a novel regulator of Wnt/β-catenin and TGF-β1/SMAD signaling pathways in colorectal cancer: an in vitro and in silico study
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    link.springer.com/article/10.1007/s11033-024-10128-0
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    ADAM17 promotes colorectal cancer migration and invasion by regulating the TGF-β/Smad signaling pathway
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    sciencedirect.com/science/article/pii/S0040816624003495
  77. www.nature.com www.nature.com
    The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression
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    nature.com/articles/s41467-024-54920-9
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    lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing
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    sciencedirect.com/science/article/pii/S1097276524008761
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    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  80. Nov 2024
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone-acetyl epigenome regulates TGF-β pathway-associated chemoresistance in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11585898/
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  83. Oct 2024
  84. aacrjournals.org aacrjournals.org
    2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis
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    aacrjournals.org/cancerres/article/81/2/289/649623/2-Hydroxylation-of-Fatty-Acids-Represses
  85. Sep 2024
  86. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CT45A1-mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell-in-cell structure, potentiating the progression of microsatellite instability-high colorectal cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13736
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    Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1097276524007317
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel immunotherapeutics against LGR5 to target multiple cancer types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
  89. www.biorxiv.org www.biorxiv.org
    Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer
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    biorxiv.org/content/10.1101/2024.09.05.611458v1
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372369/
  92. Aug 2024
  93. www.sciencedirect.com www.sciencedirect.com
    RNA interacts with topoisomerase I to adjust DNA topology
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    sciencedirect.com/science/article/pii/S1097276524006300
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Jianpi Jiedu Recipe Inhibits Proliferation through Reactive Oxygen Species-Induced Incomplete Autophagy and Reduces PD-L1 Expression in Colon Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11331576/
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    The SW480 cell line as a model of resident and migrating colon cancer stem cells
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    sciencedirect.com/science/article/pii/S2589004224018832
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    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16497
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    BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
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    sciencedirect.com/science/article/pii/S1931312824002713
  98. www.nature.com www.nature.com
    Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation
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    nature.com/articles/s41420-023-01770-x
  99. aacrjournals.org aacrjournals.org
    Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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  104. Jul 2024
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  121. Feb 2024
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  153. Jun 2023
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  155. May 2023
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  164. Mar 2023
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  168. Feb 2023
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  175. Nov 2022
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  179. Oct 2022
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  181. Sep 2022
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  191. May 2022
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  195. Apr 2022
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  206. Feb 2022
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