355 Matching Annotations
  1. Oct 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CerS2 is a druggable target in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13678703/
  3. www.sciencedirect.com www.sciencedirect.com
    Mitochondria-targeted tetraoxanes initiate lipid peroxidation to drive ferroptosis and tumor suppression
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    sciencedirect.com/science/article/pii/S0092867426011414
  4. www.sciencedirect.com www.sciencedirect.com
    Untranslated region rewiring defines a novel class of oncogene fusions
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    sciencedirect.com/science/article/pii/S2211124726012246
  5. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70746
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Verrucacrylic Acids A and B From a Marine Sponge-derived Verrucosispora sp. FIM06025
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    onlinelibrary.wiley.com/doi/full/10.1002/cbdv.71788
  7. www.sciencedirect.com www.sciencedirect.com
    Human lung explants as a predictive platform for evaluating the on-target, off-tumor toxicity of T cell bispecifics
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    sciencedirect.com/science/article/pii/S2589004226030105
  8. www.sciencedirect.com www.sciencedirect.com
    FluxAtlas is a pan-cancer metabolic flux atlas that identifies tumor-selective dependencies and prognostic biomarkers
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    sciencedirect.com/science/article/pii/S2211124726011071
  9. Sep 2026
  10. link.springer.com link.springer.com
    Integrin α2 (CD49b) blockade remodels the tumor immune microenvironment and enhances anti-PD-L1 therapy in 4T1 breast cancer model
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    link.springer.com/article/10.1007/s10549-026-08077-2
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    Cyclin E-CDK2 regulates cancer cell transcriptional program and response to immunotherapy through BRD4
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    sciencedirect.com/science/article/pii/S109727652600554X
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    E-cadherin inactivation shapes tumor microenvironment specificities in invasive lobular breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13527148/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined inhibition of PLK4 and PPM1D promotes cell death in cancer cells with 17q amplification
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    pmc.ncbi.nlm.nih.gov/articles/PMC13523465/
  14. Aug 2026
  15. 54.241.53.176 54.241.53.176
    macas-daz-et-al-2026-isoform-specific-modulation-of-pi3k-akt1-signaling-by-orai-channels-in-estrogen-receptor-html.html
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    54.241.53.176/b99daff50ca217a32dfec534fa01e5617aaa1b55/macas-daz-et-al-2026-isoform-specific-modulation-of-pi3k-akt1-signaling-by-orai-channels-in-estrogen-receptor-html.html
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    CDK8/19 inhibition prevents adaptive resistance to CDK4/6 inhibitors in vitro and in vivo
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    sciencedirect.com/science/article/pii/S2666379126004210
  17. www.sciencedirect.com www.sciencedirect.com
    Excess intracellular lactate represses mRNA translation and tumor progression through lactate-tRNA charging
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    sciencedirect.com/science/article/pii/S1097276526005125
  18. www.nature.com www.nature.com
    PGK1-driven histone lactylation fuels MDSC-driven immune evasion and tumor progression in triple-negative breast cancer
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    nature.com/articles/s41401-026-01875-w
  19. Jul 2026
  20. www.sciencedirect.com www.sciencedirect.com
    An antibody-PROTAC conjugate targets BRD4/c-Myc/PD-L1 to enhance immunotherapy efficacy in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379126003654
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphoproteomic Profiling Identifies PAK4 S474 Phosphorylation Affects Docetaxel Chemosensitivity via Modulation of Microtubule Stabilization in Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13406789/
  22. aacrjournals.org aacrjournals.org
    ESR1 Activating Mutations Confer Metabolic Vulnerabilities in ER+ Breast Cancer
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    aacrjournals.org/cancerres/article/86/3/679/771924/ESR1-Activating-Mutations-Confer-Metabolic
  23. aacrjournals.org aacrjournals.org
    SWI/SNF Functions as a Gatekeeper of Enhancer Chromatin Access to Control Progression of Mesenchymal Triple-Negative Breast Cancer
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    aacrjournals.org/cancerres/article/85/23/4648/767290/SWI-SNF-Functions-as-a-Gatekeeper-of-Enhancer
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mapping the Subtype-Specific PARP1 ADP-ribosylated Proteome in Breast Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13327525/
  25. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70290
  26. 54.241.53.176 54.241.53.176
    RET signaling as a mediator of estrogen receptor positive breast cancer brain metastasis
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    54.241.53.176/4f718a30d4dc0b6c3bcef3ab937eabf33edde44f/s42003-026-10252-6_reference-html.html
  27. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple-Negative Breast Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202520252
  28. Jun 2026
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synthesis, Biological Evaluation, and In Silico Analysis of Benzothiazolyl–Furano Thiazolidinones as Tubulin Polymerization Inhibitors
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71423
  30. www.sciencedirect.com www.sciencedirect.com
    Immunosuppressive myeloid cells induce mesenchymal-like breast cancer stem cells by a membrane-bound TGF-β1-dependent mechanism
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    sciencedirect.com/science/article/pii/S2211124726006467
  31. www.sciencedirect.com www.sciencedirect.com
    Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124726006376
  32. 54.241.53.176 54.241.53.176
    ssrn-6866900-html.html
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    54.241.53.176/af573b5d59c33d13af0955455da99e88c0385798/ssrn-6866900-html.html
  33. aacrjournals.org aacrjournals.org
    Discovery of BMS-986365, a first-in-class dual androgen receptor ligand-directed degrader (AR LDD) and antagonist, for the treatment of advanced prostate cancer
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    aacrjournals.org/clincancerres/article/32/1/224/771274/Discovery-of-BMS-986365-a-First-in-Class-Dual
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cyclin E modulates vulnerability to CDC7 kinase inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC13243581/
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Ethyl Acetate Fraction of Begonia medicinalis Herb and Ethanol Fraction of Moringa oleifera L. Leaves
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    onlinelibrary.wiley.com/doi/10.1155/jnt/3731383
  36. May 2026
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct 2-phenylimidazo[1,2-a]pyridine derivatives that inhibit breast cancer cell proliferation identified as AHR ligands
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    pmc.ncbi.nlm.nih.gov/articles/PMC13197777/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and Evaluation of Biomarkers for Triple-Negative Breast Cancer Subtypes Uncovers Patient Stratification and Targeted Therapeutic Strategies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13176827/
  39. link.springer.com link.springer.com
    Autophagy-lysosomal dependency defines a vulnerable physiological state in drug-tolerant persister cells of triple-negative breast cancer
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    link.springer.com/article/10.1007/s10495-026-02310-5
  40. link.springer.com link.springer.com
    Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer
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    link.springer.com/article/10.1007/s10495-026-02340-z
  41. aacrjournals.org aacrjournals.org
    ZSTK3744, a novel aryl hydrocarbon receptor agonist, exhibits efficacy against chemotherapy-resistant triple-negative breast cancer
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    aacrjournals.org/cancerrescommun/article/6/2/421/774901/ZSTK3744-a-Novel-Aryl-Hydrocarbon-Receptor-Agonist
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13126711/
  43. Apr 2026
  44. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226013118-main-html.html
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    54.241.53.176/bdada86f92f8761177d8d93d4fb9193d5ab10f22/1-s2.0-S2589004226013118-main-html.html
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CircNSD2 promotes metastasis and immune escape by increasing the USP10/SRSF6-mediated alternative splicing of TPM1 in TNBC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13088798/
  46. link.springer.com link.springer.com
    The GATA3-RFPL3-ASK1 axis suppresses breast cancer growth and lung metastasis
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    link.springer.com/article/10.1007/s10495-026-02335-w
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINC01929 mediates breast cancer immunosuppression and is an immunotherapy target
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    pmc.ncbi.nlm.nih.gov/articles/PMC13081058/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metastasis-associated wound repair promotes reciprocal lung epithelium activation and breast cancer metastatic outgrowth
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    pmc.ncbi.nlm.nih.gov/articles/PMC13051055/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINC01235 Is an Upstream Regulator of the NFIB Gene and the Notch Pathway in Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221212/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture
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    pmc.ncbi.nlm.nih.gov/articles/PMC13040219/
  51. Mar 2026
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Design, Synthesis, and Characterization of Novel 1,3,4-Thiadiazole-Benzo[b]Oxepine Derivatives: Study of Their Antiproliferative Activity, Docking, DFT, and ADME–T Properties
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503136
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-Cancer and Immunomodulatory Activities of Prangos ferulacea (L.) Lindl. (APIACEAE) Extracts: An In Vitro and In Vivo Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC12979902/
  54. www.nature.com www.nature.com
    N6-adenosine methylation enhances nuclear mRNA export through METTL3 and NUP93
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    nature.com/articles/s41556-026-01882-3
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CircKIAA1617 promotes stemness via USP14/PGRMC1-mediated autophagy and lipid metabolism reprogramming in ER-positive breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12952063/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sym024 interacts with a unique epitope on the CD73 homodimer, favoring effective bivalent binding to improve anti-PD1 therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12950896/
  57. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70467
  58. Feb 2026
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spermine Oxidase Serves as a Key Functional Node in Microbial Dysbiosis-Induced Breast Carcinogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12915686/
  60. www.sciencedirect.com www.sciencedirect.com
    Targeting the SIN1 mediated TTK/LDHA-H3K18la-GLUT3 Axis Disrupts Metabolic-Epigenetic Crosstalk and Suppresses Progression in Hyperglycolytic Breast Cancer
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    sciencedirect.com/science/article/pii/S0304383526000911
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12900515/
  62. www.biorxiv.org www.biorxiv.org
    IL-6R blockade with tocilizumab disrupts pericyte– and tumor cell–driven IL-6/STAT3 signaling, enhancing docetaxel efficacy in ER+ breast cancer
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    biorxiv.org/content/10.64898/2026.01.29.702661v1
  63. Jan 2026
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Notch1 regulates Orai1 and Orai3 expression in breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12830608/
  65. www.nature.com www.nature.com
    CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction
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    nature.com/articles/s41467-025-67865-4
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12747521/
  67. Dec 2025
  68. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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    sciencedirect.com:5037/science/article/pii/S2666379125005518
  69. Nov 2025
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trastuzumab Deruxtecan (T-DXd) Resistance via Loss of HER2 Expression and Binding
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    pmc.ncbi.nlm.nih.gov/articles/PMC12631751/
  71. www.sciencedirect.com www.sciencedirect.com
    System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolimus-resistant ER+ breast cancer cells
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    sciencedirect.com/science/article/pii/S2666379125004987
  72. www.sciencedirect.com www.sciencedirect.com
    Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer
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    sciencedirect.com/science/article/pii/S2666379125005026
  73. Oct 2025
  74. www.biorxiv.org www.biorxiv.org
    GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer
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    biorxiv.org/content/10.1101/2025.10.17.682994v1
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overexpression of RUNX2 promotes breast cancer multi-organ metastasis through stabilizing c-Myc
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    pmc.ncbi.nlm.nih.gov/articles/PMC12501288/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Germline-somatic liaison dictates cancer subtype via de novo steroid biosynthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12498101/
  77. www.biorxiv.org www.biorxiv.org
    Mapping the Subtype-Specific PARP1 ADP-ribosylated Proteome in Breast Cancer Cells
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    biorxiv.org/content/10.1101/2025.09.30.679484v1
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus Face of SPAG6: Inducing EMT in Luminal Breast Cancer Cells Amidst Widespread Expression Loss in Breast Tumours
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    pmc.ncbi.nlm.nih.gov/articles/PMC12510430/
  79. www.sciencedirect.com www.sciencedirect.com
    YEATS4 reads histone crotonylation to promote fatty acid metabolism and cancer cell stemness
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    sciencedirect.com/science/article/pii/S2211124725011714
  80. www.sciencedirect.com www.sciencedirect.com
    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  81. Sep 2025
  82. www.sciencedirect.com www.sciencedirect.com
    PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis
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    sciencedirect.com/science/article/pii/S266637912500429X
  83. Aug 2025
  84. www.science.org www.science.org
    Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer
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    science.org/doi/10.1126/sciadv.adt1798
  85. www.nature.com www.nature.com
    Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
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    nature.com/articles/s41467-025-62486-3
  86. www.sciencedirect.com www.sciencedirect.com
    Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance
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    sciencedirect.com/science/article/pii/S107476132500322X
  87. www.sciencedirect.com www.sciencedirect.com
    53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway
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    sciencedirect.com/science/article/pii/S2211124725009234
  88. www.sciencedirect.com www.sciencedirect.com
    Building simplified cancer subtyping and prediction models with glycan gene signatures
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    sciencedirect.com/science/article/pii/S2667237525001766
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  90. www.biorxiv.org www.biorxiv.org
    Distinct 2-phenyl-imidazo[1, 2α] pyridine derivatives drive ER degradation and selectively impair proliferation of ER+ breast cancer cells via the aryl hydrocarbon receptor
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    biorxiv.org/content/10.1101/2025.07.28.666967v1
  91. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70089
  92. Jul 2025
  93. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Curcumin Induces Homologous Recombination Deficiency by BRCA2 Degradation in Breast Cancer and Normal Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12248657/
  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232590/
  95. www.sciencedirect.com www.sciencedirect.com
    Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125002915
  96. Jun 2025
  97. www.tandfonline.com www.tandfonline.com
    Valency-affinity mapping of multivalent liposomes for tunable target cell discrimination
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