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Apr 2025
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Hypoxia-induced phase separation of ZHX2 alters chromatin looping to drive cancer metastasis

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1. scibot 05 Apr 2025
  
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  ATCCCat# HTB-133
  
  DOI: 10.1016/j.molcel.2025.03.009
  
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sciencedirect.com/science/article/pii/S1097276525002023
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Sulfatase 2 inhibition sensitizes triple-negative breast cancer cells to paclitaxel through augmentation of extracellular ATP

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1. scibot 02 Apr 2025
  
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  RRID:CVCL_0553
  
  DOI: 10.1080/15384047.2025.2483989
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11951697/
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 24 Mar 2025
  
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  RRID:CVCL_0553
  
  DOI: 10.1158/1535-7163.mct-24-0928
  
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52.53.155.43/098761c36b4439bcc578d63b667c303f01bb0050/PDF-html.html
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The transcription factor RIP140 regulates interferon γ signaling in breast cancer

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1. scibot 13 Mar 2025
  
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  DOI: 10.1002/ijc.35405
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.35405
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The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115403
  
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sciencedirect.com/science/article/pii/S2211124725001743
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FEBS Press

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1. scibot 07 Mar 2025
  
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  RRID: CVCL_0553
  
  DOI: 10.1002/1873-3468.70030
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70030
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Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids

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1. scibot 06 Mar 2025
  
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  DOI: 10.1016/j.slasd.2025.100222
  
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sciencedirect.com/science/article/pii/S2472555225000152
Feb 2025
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OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival

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1. scibot 27 Feb 2025
  
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  DOI: 10.1038/s44319-024-00361-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
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Imlunestrant Is an Oral, Brain-Penetrant Selective Estrogen Receptor Degrader with Potent Antitumor Activity in ESR1 Wild-Type and Mutant Breast Cancer

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1. scibot 19 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2608
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11831106/
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Metabolic Profiling of Breast Cancer Cell Lines: Unique and Shared Metabolites

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1. scibot 15 Feb 2025
  
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  DOI: 10.3390/ijms26030969
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11816582/
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RET inhibition overcomes resistance to combined CDK4/6 inhibitor and endocrine therapy in ER+ breast cancer

1
1. scibot 12 Feb 2025
  
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  DOI: 10.3389/fonc.2024.1497093
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11808005/
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Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor cells of metastatic breast cancer patients

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1. scibot 01 Feb 2025
  
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  DOI: 10.1038/s41598-025-87122-4
  
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nature.com/articles/s41598-025-87122-4
Jan 2025
elifesciences.org elifesciences.org

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

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1. scibot 14 Jan 2025
  
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  RRID:CVCL_0553
  
  DOI: 10.7554/eLife.93183
  
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elifesciences.org/articles/93183
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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

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1. scibot 09 Jan 2025
  
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  ATCCCat# HTB-133
  
  DOI: 10.1016/j.ccell.2024.11.008
  
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sciencedirect.com/science/article/pii/S1535610824004434
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The EstroGene2.0 database for endocrine therapy response and resistance in breast cancer

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1. scibot 04 Jan 2025
  
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  DOI: 10.1038/s41523-024-00709-4
  
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nature.com/articles/s41523-024-00709-4
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FGFR2-RUNX2 activation: An unexplored therapeutic pathway in luminal breast cancer related to tumor progression

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1. scibot 04 Jan 2025
  
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  RRID:CVCL_0553
  
  DOI: 10.1002/ijc.35302
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.35302
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FEBS Press

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1. scibot 04 Jan 2025
  
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  RRID:CVCL_0553
  
  DOI: 10.1002/1878-0261.13762
  
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febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13762
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Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma

1
1. scibot 03 Jan 2025
  
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  ATCCHTB-133
  
  DOI: 10.1016/j.isci.2024.111589
  
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sciencedirect.com/science/article/pii/S2589004224028165
Dec 2024
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Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state

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1. scibot 24 Dec 2024
  
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  RRID:CVCL_0553
  
  DOI: 10.1038/s41418-024-01439-7
  
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nature.com/articles/s41418-024-01439-7
52.53.155.43 52.53.155.43

can-24-2608-html.html

1
1. scibot 13 Dec 2024
  
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  RRID:CVCL_0553
  
  DOI: 10.1158/0008-5472.can-24-2608
  
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52.53.155.43/cf584dc99a64cef80bea76148546097bcf5b8be7/can-24-2608-html.html
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MicroRNA-145-5p inhibits the tumorigenesis of breast cancer through SENP2-regulated ubiquitination of ERK2

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1. scibot 26 Nov 2024
  
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  DOI: 10.1007/s00018-024-05505-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11584840/
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C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers

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1. scibot 21 Nov 2024
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.isci.2024.111132
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11575172/
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Aberrant expression of CD14 in breast tumor cells is associated with poor outcome

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1. scibot 14 Nov 2024
  
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  DOI: 10.1101/2024.11.07.622456
  
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biorxiv.org/content/10.1101/2024.11.07.622456v1
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A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells

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1. scibot 14 Nov 2024
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.chembiol.2024.10.008
  
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sciencedirect.com/science/article/pii/S2451945624004434
Oct 2024
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PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer

1
1. scibot 04 Oct 2024
  
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  DOI: 10.1158/1535-7163.MCT-23-0564
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443213/
Sep 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

Dynamic methylation and expression of alternative promoters for oestrogen receptor alpha in cell line models of fulvestrant resistance

1
1. scibot 27 Sep 2024
  
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  DOI: 10.1002/1878-0261.13713
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13713
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Protrusion force and cell-cell adhesion play a critical role in collective tumor cluster migration

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1. scibot 27 Sep 2024
  
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  RRID:CVCL_0553
  
  DOI: 10.1101/2024.09.18.613706
  
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biorxiv.org/content/10.1101/2024.09.18.613706v1
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Synergistic effects of PARP inhibition and cholesterol biosynthesis pathway modulation

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1. scibot 18 Sep 2024
  
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  RRID:CVCL_0553
  
  DOI: 10.1158/2767-9764.CRC-23-0549
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11403291/
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Global and single-cell proteomics view of the co-evolution between neural progenitors and breast cancer cells in a co-culture model

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1. scibot 18 Sep 2024
  
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  DOI: 10.1016/j.ebiom.2024.105325
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11404160/
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Computational pipeline predicting cell death suppressors as targets for cancer therapy

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1. scibot 17 Sep 2024
  
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  RRID: CVCL_0553
  
  DOI: 10.1016/j.isci.2024.110859
  
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sciencedirect.com/science/article/pii/S2589004224020844
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ESR1 Fusions Invoke Breast Cancer Subtype-Dependent Enrichment of Ligand-Independent Oncogenic Signatures and Phenotypes

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1. scibot 15 Sep 2024
  
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  RRID: CVCL_0553
  
  DOI: 10.1210/endocr/bqae111
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11384147/
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Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling

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1. scibot 12 Sep 2024
  
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  CVCL_0553
  
  DOI: 10.1002/cti2.1524
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11378723/
Aug 2024
www.cell.com www.cell.com

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.cell.2020.02.019
  
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cell.com/cell/fulltext/S0092-8674(20)30163-X
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The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer

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1. scibot 21 Aug 2024
  
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  RRID:CVCL_0553
  
  DOI: 10.3390/cancers16152663
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11311709/
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TAS3681, an androgen receptor antagonist, prevents drug resistance driven by aberrant androgen receptor signaling in prostate cancer

1
1. scibot 21 Aug 2024
  
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  DOI: 10.1002/1878-0261.13641
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11306513/
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HTS384 NCI60: The Next Phase of the NCI60 Screen

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1. scibot 18 Aug 2024
  
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  RRID:CVCL_0553
  
  DOI: 10.1158/0008-5472.CAN-23-3031
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
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Human 3D ovarian cancer models reveal malignant cell intrinsic and extrinsic factors that influence CAR T cell activity

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1. scibot 18 Aug 2024
  
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ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines

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Small molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in estrogen receptor-positive breast cancer overcomes tamoxifen resistance

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The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer

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TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells

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Alternative promoters and splicing create multiple functionally distinct isoforms of oestrogen receptor alpha in breast cancer and healthy tissues

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The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization

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Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis

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Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance

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Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton

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EstroGene2.0: A multi-omic database of response to estrogens, ER-modulators, and resistance to endocrine therapies in breast cancer

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BPS Publications

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HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice

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Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite

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Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease

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eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer

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Intracellular Retention of Estradiol is Augmented by GRAM Domain Containing Protein ASTER-B in Breast Cancer Cells

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KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer

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Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers

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MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer

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Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer

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Potent Estrogen Receptor β Agonists with Inhibitory Activity In Vitro, Fail to Suppress Xenografts of Endocrine-Resistant Cyclin-dependent Kinase 4/6 inhibitor-Resistant Breast Cancer Cells

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Genetic dependencies associated with transcription factor activities in human cancer cell lines

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Cis-regulatory control of transcriptional timing and noise in response to estrogen

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Cryo-EM structures reveal two allosteric inhibition modes of PI3KαH1047R involving a re-shaping of the activation loop

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Abemaciclib is effective in palbociclib-resistant hormone receptor-positive metastatic breast cancers

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MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer

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TRPS1 modulates chromatin accessibility to regulate estrogen receptor alpha (ER) binding and ER target gene expression in luminal breast cancer cells

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Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer

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The transcription factor RIP140 regulates interferon γ signaling in breast cancer

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cd-23-0954-html.html

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Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting

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SAA1-dependent reprogramming of adipocytes by tumor cells is associated with triple negative breast cancer aggressiveness

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Profiling of ERBB receptors and downstream pathways reveals selectivity and hidden properties of ERBB4 antagonists

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An estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2

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SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion

1
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Liver X receptors induce antiproliferative effects in basal‐like breast cancer

1
1. scibot 25 Jan 2024
  
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Clonal heterogeneity in ER+ breast cancer reveals the proteasome and PKC as potential therapeutic targets

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Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk

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Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer

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G-quadruplex is critical to epigenetic activation of the lncRNA HOTAIR in cancer cells

1
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Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer

1
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Nov 2023
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Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest

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Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism

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Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy

1
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Oct 2023
52.53.155.43 52.53.155.43

FEBS Press

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52.53.155.43/dbe8c3e3fbcbeef5c4f8f35843262b8cfb5dca0c/Molecular Oncology - 2023 - Liu - USP7 reduces the level of nuclear DICER impairing DNA damage response and promoting-html.html
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NR1D1 Stimulates Antitumor Immune Responses in Breast Cancer by Activating cGAS-STING Signaling

2
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Targeting Solid Cancers with a Cancer-Specific Monoclonal Antibody to Surface Expressed Aberrantly O-glycosylated Proteins

1
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Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer

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Kinome reprogramming is a targetable vulnerability in ESR1 fusion-driven breast cancer

1
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Sep 2023
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Natural killer cell therapy targeting cancer stem cells: Old wine in a new bottle

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Aug 2023
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PIIS2589004223016838-html.html

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Jul 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c-MYC and NFkB activation in breast cancer

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TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells

1
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  DOI: 10.1101/2023.07.03.547524
  
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Jun 2023
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Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

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FOXA1 reprogramming dictates retinoid X receptor response in ESR1 mutant breast cancer

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NAD + Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females

1
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  DOI: 10.1210/endocr/bqad073
  
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52.53.155.43 52.53.155.43

can-22-3484-html.html

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link.springer.com link.springer.com

KDM4B down-regulation facilitated breast cancer cell stemness via PHGDH upregulation in H3K36me3-dependent manner

1
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May 2023
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G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis

1
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  DOI: 10.18632/oncotarget.28433
  
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Primary breast cancer biomarkers based on glycosylation and extracellular vesicles detected from human serum

1
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  DOI: 10.1002/cnr2.1540
  
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onlinelibrary.wiley.com/doi/full/10.1002/cnr2.1540
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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  DOI: 10.1002/1878-0261.13436
  
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IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization

1
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  DOI: 10.1016/j.chembiol.2023.04.005
  
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Apr 2023
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LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism

1
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  DOI: 10.1038/s41467-023-37871-5
  
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Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

1
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  DOI: 10.1158/2767-9764.CRC-22-0310
  
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N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer

1
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  DOI: 10.1016/j.xcrm.2023.101002
  
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Mar 2023
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Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

1
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  DOI: 10.1158/1541-7786.MCR-22-0090
  
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Sustained oncogenic signaling in the cytostatic state enables targeting of non-proliferating persistent cancer cells

1
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  DOI: 10.1158/0008-5472.CAN-21-2908
  
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Feb 2023
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Targeting mTOR to overcome resistance to hormone and CDK4/6 inhibitors in ER-positive breast cancer models

1
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  DOI: 10.1038/s41598-023-29425-y
  
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nature.com/articles/s41598-023-29425-y
Jan 2023
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Human Endogenous Retroviruses in Cancer: Oncogenesis mechanisms and Clinical Implications

1
1. scibot 10 Jan 2023
  
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  DOI: 10.1002/jmv.28350
  
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onlinelibrary.wiley.com/doi/10.1002/jmv.28350
Dec 2022
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DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy

1
1. scibot 31 Dec 2022
  
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  DOI: 10.3389/fonc.2022.1052163
  
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Conformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy

1
1. scibot 30 Dec 2022
  
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  DOI: 10.1038/s41598-022-26404-7
  
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can-22-0787-html.html

2
1. scibot 09 Dec 2022
  
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  RRID:CVCL_0553
  
  DOI: 10.1158/0008-5472.CAN-22-0787
  
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  DOI: 10.1158/0008-5472.can-22-0787
  
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Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

2
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  DOI: 10.1158/1541-7786.MCR-21-0781
  
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  DOI: 10.1158/1541-7786.MCR-21-0781
  
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Table 1 Tumor cell lines used to set up common subcutaneous mouse tumor models

1
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nature.com/articles/s41596-022-00709-3/tables/1
Nov 2022
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PARP10 Mediates Mono-ADP-Ribosylation of Aurora-A Regulating G2/M Transition of the Cell Cycle

1
1. scibot 18 Nov 2022
  
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  DOI: 10.3390/cancers14215210
  
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Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha

1
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  DOI: 10.1016/j.molcel.2022.10.030
  
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Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis

1
1. scibot 16 Nov 2022
  
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Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

1
1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111652
  
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Oct 2022
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COMPREHENSIVE DRUG RESPONSE PROFILING AND PAN-OMIC ANALYSIS IDENTIFIED THERAPEUTIC CANDIDATES AND PROGNOSTIC BIOMARKERS FOR ASIAN CHOLANGIOCARCINOMA

1
1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105182
  
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Aug 2022
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can-21-2908-html.html

1
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  DOI: 10.1158/0008-5472.CAN-21-2908
  
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52.53.155.43/e58395037b6fc963ccf3afdad25ef582040a5a24/can-21-2908-html.html
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Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone

1
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  DOI: 10.3389/fendo.2022.888802
  
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Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression

1
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  DOI: 10.1016/j.molcel.2022.07.014
  
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CD146 interaction with integrin β1 activates LATS1-YAP signaling and induces radiation-resistance in breast cancer cells

1
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.canlet.2022.215856
  
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sciencedirect.com/science/article/pii/S0304383522003408
Jul 2022
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Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness

1
1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.isci.2022.104721
  
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Anastrozole regulates fatty acid synthase in breast cancer

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  DOI: 10.1158/1535-7163.MCT-21-0509
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8742770/
Jun 2022
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Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer

1
1. scibot 30 Jun 2022
  
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  DOI: 10.1158/0008-5472.CAN-21-1256
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9234971/
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Antagonists of the Mu-Opioid Receptor in the Cancer Patient: Fact or Fiction?

1
1. scibot 04 Jun 2022
  
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  DOI: 10.1007/s11912-022-01295-z
  
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link.springer.com/article/10.1007/s11912-022-01295-z
May 2022
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Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer

1
1. scibot 18 May 2022
  
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  CVCL_0553
  
  DOI: 10.3389/fonc.2022.857590
  
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Annexin A2: The Diversity of Pathological Effects in Tumorigenesis and Immune Response

1
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  DOI: 10.1002/ijc.34048
  
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Production and optimization of a vasostatin-30 and vasoinhibin fusion protein that inhibits tumor angiogenesis and dissemination of breast cancer cells in a zebrafish model

1
1. scibot 10 May 2022
  
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  DOI: 10.1016/j.procbio.2022.05.002
  
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sciencedirect.com/science/article/pii/S1359511322001635
Apr 2022
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Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer

1
1. scibot 21 Apr 2022
  
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  ATCCCat# HTB-133
  
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Intraoperative MET-receptor targeted fluorescent imaging and spectroscopy for lymph node detection in papillary thyroid cancer: novel diagnostic tools for more selective central lymph node compartment dissection

1
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Mar 2022
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A defect of amphiregulin release predicted longer survival independently of YAP expression in patients with pleural mesothelioma in the IFCT-0701 MAPS phase 3 trial

1
1. scibot 26 Mar 2022
  
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  RRID:CVCL_0553
  
  DOI: 10.1002/ijc.33997
  
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.33997
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A novel HIF-2α targeted inhibitor suppresses hypoxia-induced breast cancer stemness via SOD2-mtROS-PDI/GPR78-UPRER axis

1
1. scibot 23 Mar 2022
  
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nature.com/articles/s41418-022-00963-8
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MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding

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  DOI: 10.1158/2767-9764.CRC-21-0103
  
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aacrjournals.org/cancerrescommun/article/2/2/110/681605/MYC-Inhibition-Halts-Metastatic-Breast-Cancer
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Recruitment of DNA to tumor-derived microvesicles

1
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.celrep.2022.110443
  
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Feb 2022
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An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer

1
1. scibot 16 Feb 2022
  
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  DOI: 10.1016/j.xcrm.2022.100525
  
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What enzyme-modified proteins are able to do

1
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  DOI: 10.1016/B978-0-323-89929-1.00001-9
  
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Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast

1
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  DOI: 10.1158/1541-7786.MCR-21-0025
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8349796/
Jan 2022
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Progesterone receptor isoform ratio dictates antiprogestin/progestin effects on breast cancer growth and metastases: A role for NDRG1

1
1. scibot 27 Jan 2022
  
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  DOI: 10.1002/ijc.33913
  
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Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells

1
1. scibot 07 Jan 2022
  
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  DOI: 10.7554/eLife.69843
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
Dec 2021
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IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer

1
1. scibot 22 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110138
  
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Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors

1
1. scibot 22 Dec 2021
  
  in Public
  
  RRID:CVCL_0553
  
  DOI: 10.1016/j.xcrm.2021.100457
  
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NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis

1
1. scibot 08 Dec 2021
  
  in Public
  
  HTB-133
  
  DOI: 10.1016/j.cmet.2021.11.011
  
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Polypeptide-GalNAc-Transferase-13 Shows Prognostic Impact in Breast Cancer

1
1. scibot 01 Dec 2021
  
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  RRID: CVCL_0553
  
  DOI: 10.3390/cancers13225616
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8616257/
Nov 2021
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GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12

1
1. scibot 09 Nov 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.isci.2021.103311
  
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Genomic alterations in PIK3CA-mutated breast cancer result in mTORC1 activation and limit the sensitivity to PI3Kα inhibitors

1
1. scibot 05 Nov 2021
  
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  CVCL_0553
  
  DOI: 10.1158/0008-5472.CAN-20-3232
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8137641/
Oct 2021
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Prognostic Value of GILT Expression in Female Patients Diagnosed with Breast Cancer

1
1. scibot 29 Oct 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1002/ijc.33843
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33843
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Beta 2 Adrenergic Receptor Antagonist Propranolol and Opioidergic Receptor Antagonist Naltrexone Produce Synergistic Effects on Breast Cancer Growth Prevention by Acting on Cancer Cells and Immune Environment in a Preclinical Model of Breast Cancer

1
1. scibot 15 Oct 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.3390/cancers13194858
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8508249/
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NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer

1
1. scibot 08 Oct 2021
  
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  HTB-133
  
  DOI: 10.1016/j.molcel.2021.09.016
  
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In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target

1
1. scibot 28 Sep 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.cell.2021.09.006
  
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Oncogene-dependent sloppiness in mRNA translation

1
1. scibot 25 Sep 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.molcel.2021.09.002
  
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ERα determines the chemoresistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions

1
1. scibot 24 Sep 2021
  
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  RRID: CVCL_0553
  
  DOI: 10.1016/j.omtn.2021.07.022
  
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sciencedirect.com/science/article/pii/S2162253121001906
Aug 2021
link.springer.com link.springer.com

YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models

1
1. scibot 31 Aug 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1007/s13402-021-00630-z
  
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Generation of hypoxia-sensing chimeric antigen receptor T cells

1
1. scibot 10 Aug 2021
  
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  HTB-133
  
  DOI: 10.1016/j.xpro.2021.100723
  
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As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid

1
1. scibot 08 Aug 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.cmet.2017.12.006
  
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sciencedirect.com/science/article/pii/S1550413117307167
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BBIT20 inhibits homologous DNA repair with disruption of the BRCA1‐BARD1 interaction in breast and ovarian cancer

1
1. scibot 06 Aug 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1111/bph.15506
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15506
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Untitled document

1
1. scibot 05 Aug 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.ccell.2018.11.006
  
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sciencedirect.com/science/article/pii/S1535610818305270
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Untitled document

1
1. scibot 02 Aug 2021
  
  in Public
  
  CVCL_0553
  
  DOI: 10.1002/jcb.27887
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcb.27887
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

1
1. scibot 01 Aug 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1002/jcp.27013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6202151/
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Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

1
1. scibot 01 Aug 2021
  
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  CVCL_0553
  
  DOI: 10.1016/j.cels.2019.11.001
  
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sciencedirect.com/science/article/pii/S2405471219303874
Jul 2021
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Hedgehog Acyltransferase Promotes Uptake of Palmitoyl-CoA across the Endoplasmic Reticulum Membrane

1
1. scibot 31 Jul 2021
  
  in Public
  
  T47D
  
  DOI: 10.1016/j.celrep.2019.11.110
  
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sciencedirect.com/science/article/pii/S221112471931633X
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The Cancer SENESCopedia: A delineation of cancer cell senescence

1
1. scibot 30 Jul 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.celrep.2021.109441
  
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sciencedirect.com/science/article/pii/S2211124721008585
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Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

1
1. scibot 30 Jul 2021
  
  in Public
  
  Human: T-47D
  
  DOI: 10.1016/j.celrep.2019.08.076
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
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sciencedirect.com/science/article/pii/S2211124719311313
academic.oup.com academic.oup.com

Mechanism of Telapristone Acetate (CDB4124) on Progesterone Receptor Action in Breast Cancer Cells

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:CVCL_0553
  
  DOI: 10.1210/en.2018-00559
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
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academic.oup.com/endo/article/159/10/3581/5091403
rupress.org rupress.org

Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival

1
1. scibot 29 Jul 2021
  
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  RRID: CVCL_0553
  
  DOI: 10.1083/jcb.201904051
  
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rupress.org/jcb/article/218/11/3827/120917/Chemotherapy-induced-senescent-cancer-cells-engulf
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Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.molcel.2019.06.020
  
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sciencedirect.com/science/article/pii/S1097276519304769
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The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death

1
1. scibot 29 Jul 2021
  
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  RRID: CVCL_0553
  
  DOI: 10.1016/j.cell.2019.05.035
  
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sciencedirect.com/science/article/pii/S009286741930563X
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Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

1
1. scibot 29 Jul 2021
  
  in Public
  
  Human: T47D
  
  DOI: 10.1016/j.cmet.2019.06.014
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
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  RRID:CVCL_0553 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1550413119303171
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

LIPG signaling promotes tumor initiation and metastasis of human basal-like triple-negative breast cancer

2
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:CVCL_0553
  
  DOI: 10.7554/eLife.31334
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
  Curator: @evieth
  
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  RRID:CVCL_0553 RRIDCUR:Duplicate RRIDCUR:Validated
2. scibot 29 Jul 2021
  
  in Public
  
  RRID:CVCL_0553
  
  DOI: 10.7554/eLife.31334
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5809145/
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Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

1
1. scibot 28 Jul 2021
  
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  RRID: CVCL_0553
  
  DOI: 10.1016/j.chembiol.2019.05.005
  
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sciencedirect.com/science/article/pii/S2451945619301746
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PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression

1
1. scibot 28 Jul 2021
  
  in Public
  
  Human T47D breast cancer cells
  
  DOI: 10.1016/j.celrep.2019.02.111
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
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  RRID:CVCL_0553 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124719302979
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Mutual regulations and breast cancer cell control by steroidogenic enzymes: dual sex-hormone receptor modulation upon 17β-HSD7 inhibition

1
1. scibot 27 Jul 2021
  
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  RRID: CVCL-0553
  
  DOI: 10.1016/j.jsbmb.2019.105411
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
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  RRID:CVCL_0553 RRIDCUR:SyntaxError
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sciencedirect.com/science/article/pii/S0960076019301384
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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

1
1. scibot 27 Jul 2021
  
  in Public
  
  HTB-133
  
  DOI: 10.1016/j.ccell.2018.10.014
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
  Curator: @Jmenke
  
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  RRID:CVCL_0553 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S153561081830480X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion

1
1. scibot 27 Jul 2021
  
  in Public
  
  T47D
  
  DOI: 10.1186/s13058-017-0890-x
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
  Curator: @mpairish
  
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  RRID:CVCL_0553 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC5562991/
onlinelibrary.wiley.com onlinelibrary.wiley.com

The GEF‐H1/PKD3 signaling pathway promotes the maintenance of triple negative breast cancer stem cells

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:CVCL_055
  
  DOI: 10.1002/ijc.32798
  
  Resource: (BCRC Cat# 60250, RRID:CVCL_0553)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0553
  
  Curator comments: T-47D cell line NCI-DTP Cat# T-47D
  
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  RRID:CVCL_0553 RRIDCUR:Unresolved RRIDCUR:Incorrect
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onlinelibrary.wiley.com/doi/10.1002/ijc.32798
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ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

1
1. scibot 22 Jul 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.xcrm.2021.100350
  
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sciencedirect.com/science/article/pii/S2666379121001993
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Single-cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells

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1. scibot 16 Jul 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1158/0008-5472.CAN-20-0696
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7856056/
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Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target

1
1. scibot 01 Jul 2021
  
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  T47D
  
  DOI: 10.1016/j.biocel.2021.106028
  
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sciencedirect.com/science/article/pii/S1357272521001060
Jun 2021
mcr.aacrjournals.org mcr.aacrjournals.org

Development and Characterization of Novel Endoxifen-Resistant Breast Cancer Cell Lines Highlight Numerous Differences from Tamoxifen-Resistant Models

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1. scibot 29 Jun 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1158/1541-7786.MCR-20-0872
  
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mcr.aacrjournals.org/content/19/6/1026
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Metabolic imaging with hyperpolarized [1-13C] pyruvate in patient-derived preclinical mouse models of breast cancer

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1. scibot 18 Jun 2021
  
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  RRID: CVCL_0553
  
  DOI: 10.1016/j.xpro.2021.100608
  
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Long noncoding RNA ENST00000508435 promotes migration of breast cancer via FXR 1

1
1. scibot 11 Jun 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1080/19336918.2021.1921402
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8168597/
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Oxytocin receptor induces mammary tumorigenesis through prolactin/p-STAT5 pathway

1
1. scibot 11 Jun 2021
  
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  CVCL_0553
  
  DOI: 10.1038/s41419-021-03849-8
  
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nature.com/articles/s41419-021-03849-8
May 2021
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PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells

1
1. scibot 07 May 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.molcel.2020.08.018
  
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Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment

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1. scibot 05 May 2021
  
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  HTB-133
  
  DOI: 10.1016/j.devcel.2020.07.014
  
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sciencedirect.com/science/article/pii/S1534580720305888
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Deciphering the signaling network of breast cancer improves drug sensitivity prediction

1
1. scibot 01 May 2021
  
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  HTB-133
  
  DOI: 10.1016/j.cels.2021.04.002
  
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sciencedirect.com/science/article/pii/S2405471221001113
Apr 2021
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The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development

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1. scibot 29 Apr 2021
  
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  HTB-133
  
  DOI: 10.1016/j.cmet.2020.05.008
  
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Efficient inhibition of O-glycan biosynthesis using the hexosamine analog Ac5GalNTGc

1
1. scibot 28 Apr 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.chembiol.2021.01.017
  
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FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer

1
1. scibot 22 Apr 2021
  
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  HTB-133
  
  DOI: 10.1016/j.ccell.2020.08.003
  
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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

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1. scibot 20 Apr 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.ccell.2020.06.007
  
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cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
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The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells

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1. scibot 20 Apr 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.devcel.2021.03.008
  
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Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis

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1. scibot 11 Apr 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.1016/j.molcel.2021.01.033
  
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Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation

1
1. scibot 07 Apr 2021
  
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  HTB-133
  
  DOI: 10.1016/j.cmet.2021.03.006
  
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Mar 2021
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IP6K2 predicts favorable clinical outcome of primary breast cancer

1
1. scibot 28 Mar 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.3892/mco.2021.2256
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7976380/
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TRPS1 drives heterochromatic origin refiring and cancer genome evolution

1
1. scibot 11 Mar 2021
  
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  ATCC HTB-133
  
  DOI: 10.1016/j.celrep.2021.108814
  
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sciencedirect.com/science/article/pii/S2211124721001285
Feb 2021
elifesciences.org elifesciences.org

Synergistic interactions with PI3K inhibition that induce apoptosis

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1. scibot 26 Feb 2021
  
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  RRID:CVCL_0553
  
  DOI: 10.7554/eLife.24523
  
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TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions

1
1. scibot 24 Feb 2021
  
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  HTB-133
  
  DOI: 10.1016/j.celrep.2021.108776
  
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sciencedirect.com/science/article/pii/S2211124721000899

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