Hypothesis

96 Matching Annotations

Feb 2026
54.241.53.176 54.241.53.176

1-s2.0-S2590018826000031-main-html.html

1
1. scibot 10 Feb 2026
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.iotech.2026.101584
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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54.241.53.176/801ef474ffa9d4106a07843e039803a96ccc096b/1-s2.0-S2590018826000031-main-html.html
Jan 2026
www.sciencedirect.com www.sciencedirect.com

ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia

1
1. scibot 09 Jan 2026
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.xcrm.2025.102540
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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sciencedirect.com/science/article/pii/S2666379125006135
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A novel strategy to target metabolic dependencies in acute myeloid leukemia

1
1. scibot 07 Nov 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1038/s41419-025-08129-3
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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pmc.ncbi.nlm.nih.gov/articles/PMC12586699/
Oct 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

1
1. scibot 28 Oct 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1002/advs.202511573
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511573
www.biorxiv.org www.biorxiv.org

Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML

1
1. scibot 23 Oct 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1101/2025.10.13.682235
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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biorxiv.org/content/10.1101/2025.10.13.682235v1
www.science.org www.science.org

Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia

1
1. scibot 21 Oct 2025
  
  in Public
  
  CRL-2724
  
  DOI: 10.1126/sciadv.adx8662
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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science.org/doi/10.1126/sciadv.adx8662
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Jab1 promotes immune evasion and progression in acute myeloid leukemia models under oxidative stress

1
1. scibot 16 Oct 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1172/JCI183761
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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pmc.ncbi.nlm.nih.gov/articles/PMC12520683/
www.sciencedirect.com www.sciencedirect.com

Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation

1
1. scibot 02 Oct 2025
  
  in Public
  
  ATCCCRL-2724
  
  DOI: 10.1016/j.celrep.2025.116379
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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sciencedirect.com/science/article/pii/S2211124725011507
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens

1
1. scibot 27 Sep 2025
  
  in Public
  
  ATCCCRL-2724
  
  DOI: 10.1016/j.cell.2025.09.001
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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sciencedirect.com/science/article/pii/S0092867425010323
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Enhancing Anti-Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression

1
1. scibot 27 Sep 2025
  
  in Public
  
  RRID: CVCL_0589
  
  DOI: 10.1002/advs.202515472
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515472
Aug 2025
www.nature.com www.nature.com

The bispecific innate cell engager AFM28 eliminates CD123+ leukemic stem and progenitor cells in AML and MDS

1
1. scibot 27 Aug 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1038/s41467-025-63069-y
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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nature.com/articles/s41467-025-63069-y
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 21 Aug 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1111/bph.70158
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70158
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer

1
1. scibot 04 Jul 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1158/1535-7163.MCT-24-0699
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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URL

pmc.ncbi.nlm.nih.gov/articles/PMC12214875/
May 2025
www.cell.com www.cell.com

CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models

1
1. scibot 29 May 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.xcrm.2025.102148
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway–Deficient Acute Myeloid Leukemia

1
1. scibot 24 Apr 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1158/2767-9764.CRC-24-0260
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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pmc.ncbi.nlm.nih.gov/articles/PMC12011380/
52.53.155.43 52.53.155.43

Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma

1
1. scibot 11 Apr 2025
  
  in Public
  
  ATCC CRL-2724
  
  DOI: 10.1101/2024.10.22.617161
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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52.53.155.43/5480965c1766ce5dc1f2ceec9f18c523a1b9a8ab/2024.10.22.617161.full-html.html
Mar 2025
www.sciencedirect.com www.sciencedirect.com

A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies

1
1. scibot 28 Mar 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2025.03.007
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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URL

sciencedirect.com/science/article/pii/S1535610825001084
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 23 Mar 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1158/2767-9764.crc-24-0260
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

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52.53.155.43/bd8b1eb80c0a90d93d052e69613b249b6f3108d9/PDF-html.html
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PROTAC-Mediated GSPT1 Degradation Impairs the Expression of Fusion Genes in Acute Myeloid Leukemia

1
1. scibot 29 Jan 2025
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.3390/cancers17020211
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11763475/
www.sciencedirect.com www.sciencedirect.com

A thermoplastic chip for 2D and 3D correlative assays combining screening and high-resolution imaging of immune cell responses

1
1. scibot 23 Jan 2025
  
  in Public
  
  ATCCCRL-2724
  
  DOI: 10.1016/j.crmeth.2025.100965
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

sciencedirect.com/science/article/pii/S2667237525000013
Dec 2024
www.sciencedirect.com www.sciencedirect.com

YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies

1
1. scibot 18 Dec 2024
  
  in Public
  
  CVCL_0589
  
  DOI: 10.1016/j.cell.2024.11.007
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424013242
www.sciencedirect.com www.sciencedirect.com

B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies

1
1. scibot 02 Dec 2024
  
  in Public
  
  CVCL_0589
  
  DOI: 10.1016/j.ebiom.2024.105459
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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sciencedirect.com/science/article/pii/S235239642400495X
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Tunable, division-independent control of gene activation timing by a polycomb switch

1
1. scibot 25 Aug 2024
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2021.108888
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589 RRIDCUR:Validated
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RRID:CVCL_0589

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721002023
www.cell.com www.cell.com

SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation

1
1. scibot 18 Aug 2024
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2024.114536
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling

1
1. scibot 17 Jul 2024
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.xcrm.2024.101645
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

1
1. scibot 04 Jun 2024
  
  in Public
  
  CRL-2724
  
  DOI: 10.1016/j.devcel.2024.05.010
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589 DOI:10.1016/j.devcel.2024.05.010
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DOI:10.1016/j.devcel.2024.05.010

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scibot

URL

sciencedirect.com/science/article/pii/S1534580724003277
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers

1
1. scibot 26 Apr 2024
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2024.04.004
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

sciencedirect.com/science/article/pii/S1535610824001284
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FEBS Press

2
1. scibot 15 Mar 2024
  
  in Public
  
  CVCL_0589
  
  DOI: 10.1002/1878-0261.13630
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
  What is this?
  
  RRID:CVCL_0589
2. scibot 15 Mar 2024
  
  in Public
  
  CVCL_0589
  
  DOI: 10.1002/1878-0261.13630
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC11467801/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells

1
1. scibot 15 Feb 2024
  
  in Public
  
  ATCC# CRL-2724
  
  DOI: 10.1016/j.cmet.2024.01.013
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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URL

sciencedirect.com/science/article/pii/S1550413124000135
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth

1
1. scibot 15 Feb 2024
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1038/s41467-024-45691-4
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10867020/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells

1
1. scibot 03 Feb 2024
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1158/0008-5472.CAN-23-1632
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The predictive value of BTG1 for the response of newly diagnosed acute myeloid leukemia to decitabine

1
1. scibot 24 Jan 2024
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1186/s13148-024-01627-9
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10802042/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

A helicase-independent role of DHX15 promotes MYC stability and acute leukemia cell survival

1
1. scibot 21 Dec 2023
  
  in Public
  
  ATCCCat# CRL-2724
  
  DOI: 10.1016/j.isci.2023.108571
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

sciencedirect.com/science/article/pii/S2589004223026482
www.biorxiv.org www.biorxiv.org

MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells

1
1. scibot 01 Dec 2023
  
  in Public
  
  CVCL_0589
  
  DOI: 10.1101/2023.11.15.567209
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0589
  
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  RRID:CVCL_0589
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RRID:CVCL_0589

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scibot

URL

biorxiv.org/content/10.1101/2023.11.15.567209v1
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

1
1. scibot 22 Nov 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.xcrm.2023.101290
  
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Oct 2023
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Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease

1
1. scibot 13 Oct 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.xcrm.2023.101236
  
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sciencedirect.com/science/article/pii/S2666379123004135
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15

2
1. scibot 29 Sep 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.isci.2023.107844
  
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  DOI: 10.1016/j.isci.2023.107844
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
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Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment

1
1. scibot 16 Sep 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2023.113098
  
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Jun 2023
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Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

1
1. scibot 24 Jun 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1038/s41467-023-39241-7
  
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nature.com/articles/s41467-023-39241-7
May 2023
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Leukemic stem cells hijack lineage inappropriate signalling pathways to promote their growth

1
1. scibot 04 May 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1101/2023.03.10.532081
  
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biorxiv.org/content/10.1101/2023.03.10.532081v2
Mar 2023
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Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells

1
1. scibot 11 Mar 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.xcrm.2023.100962
  
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Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells

1
1. scibot 10 Mar 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2023.02.010
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
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BPS Publications

1
1. scibot 03 Mar 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1111/bph.16028
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16028
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Preclinical evaluation of CD70-specific CAR T cells targeting acute myeloid leukemia

2
1. scibot 02 Mar 2023
  
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  RRID: CVCL_0589
  
  DOI: 10.3389/fimmu.2023.1093750
  
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  DOI: 10.3389/fimmu.2023.1093750
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9950117/
Feb 2023
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Transcriptionally imprinted glycomic signatures of acute myeloid leukemia

1
1. scibot 17 Feb 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1186/s13578-023-00981-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9926860/
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ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD

1
1. scibot 17 Feb 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1002/1878-0261.13368
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13368
Jan 2023
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Human SMARCA5 is continuously required to maintain nucleosome spacing

1
1. scibot 12 Jan 2023
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.molcel.2022.12.018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9974918/
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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

1
1. scibot 06 Jan 2023
  
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  RRID: CVCL_0589
  
  DOI: 10.1016/j.stem.2022.12.006
  
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sciencedirect.com/science/article/pii/S1934590922004908
Dec 2022
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Implications of differential transcription start site selection on chronic myeloid leukemia and prostate cancer cell protein expression

1
1. scibot 02 Dec 2022
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.isci.2022.105519
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9678739/
Oct 2022
www.cell.com www.cell.com

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

1
1. scibot 28 Oct 2022
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2022.10.004
  
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cell.com/cancer-cell/fulltext/S1535-6108(22)00495-0
Sep 2022
elifesciences.org elifesciences.org

Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

1
1. scibot 22 Sep 2022
  
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  RRID:CVCL_0589
  
  DOI: 10.7554/eLife.75908
  
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Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance

1
1. scibot 10 Sep 2022
  
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  CVCL_0589
  
  DOI: 10.1155/2022/2813938
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9448541/
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Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance

1
1. scibot 07 Sep 2022
  
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  CVCL_0589
  
  DOI: 10.1155/2022/2813938
  
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hindawi.com/journals/jo/2022/2813938/
Aug 2022
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hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia

2
1. scibot 17 Aug 2022
  
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  RRID: CVCL_0589
  
  DOI: 10.1016/j.xcrm.2022.100717
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.xcrm.2022.100717
  
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sciencedirect.com/science/article/pii/S2666379122002609
Jun 2022
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Optimization and validation of CAR transduction into human primary NK cells using CRISPR and AAV

1
1. scibot 15 Jun 2022
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.crmeth.2022.100236
  
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sciencedirect.com/science/article/pii/S2667237522001059
May 2022
www.tandfonline.com www.tandfonline.com

JMJD1C-regulated lipid synthesis contributes to the maintenance of MLL-rearranged acute myeloid leukemia

1
1. scibot 11 May 2022
  
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  RRID:CVCL_0589
  
  DOI: 10.1080/10428194.2022.2068004
  
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tandfonline.com/doi/abs/10.1080/10428194.2022.2068004
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Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

1
1. scibot 06 May 2022
  
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  DSMZACC 220
  
  DOI: 10.1016/j.stem.2022.04.007
  
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sciencedirect.com/science/article/pii/S1934590922001606
Apr 2022
aacrjournals.org aacrjournals.org

Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia

1
1. scibot 05 Apr 2022
  
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  RRID:CVCL_0589
  
  DOI: 10.1158/2159-8290.CD-21-0692
  
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aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
Mar 2022
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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML

1
1. scibot 09 Mar 2022
  
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  ATCCCRL-2724
  
  DOI: 10.1016/j.celrep.2022.110481
  
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sciencedirect.com/science/article/pii/S2211124722002145
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The proteogenomic subtypes of acute myeloid leukemia

1
1. scibot 04 Mar 2022
  
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  CVCL_0589
  
  DOI: 10.1016/j.ccell.2022.02.006
  
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sciencedirect.com/science/article/pii/S1535610822000587
Jan 2022
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Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2

1
1. scibot 26 Jan 2022
  
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  ATCCCRL-2724
  
  DOI: 10.1016/j.celrep.2021.110253
  
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sciencedirect.com/science/article/pii/S2211124721017654
Dec 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells

1
1. scibot 17 Dec 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1002/ijc.33865
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33865
Sep 2021
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Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia

1
1. scibot 22 Sep 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2021.109725
  
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sciencedirect.com/science/article/pii/S2211124721011748
Aug 2021
www.nature.com www.nature.com

Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

1
1. scibot 11 Aug 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1038/s41467-021-24821-2
  
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nature.com/articles/s41467-021-24821-2
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The BET bromodomain inhibitor ZEN-3365 targets the Hedgehog signaling pathway in acute myeloid leukemia

1
1. scibot 04 Aug 2021
  
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  RRID:_CVCL_0589
  
  DOI: 10.1007/s00277-021-04602-z
  
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  Curator: @Naa003
  
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link.springer.com/article/10.1007/s00277-021-04602-z
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The immune landscape of chondrosarcoma reveals an immunosuppressive environment and exposes macrophages as a promising therapeutic target

1
1. scibot 01 Aug 2021
  
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  CVCL_0589
  
  DOI: 10.1016/j.jbo.2019.100271
  
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Small Molecular Modulators of JMJD1C Preferentially Inhibit Growth of Leukemia Cells

1
1. scibot 01 Aug 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1002/ijc.32552
  
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onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32552
Jul 2021
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A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

1
1. scibot 31 Jul 2021
  
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  Human: Kasumi-1
  
  DOI: 10.1016/j.ccell.2019.10.002
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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sciencedirect.com/science/article/pii/S1535610819304763
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1. scibot 31 Jul 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2018.08.015
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6179967/
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RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

1
1. scibot 30 Jul 2021
  
  in Public
  
  Kasumi-1 human cell line
  
  DOI: 10.1016/j.celrep.2019.08.040
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719310800
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1. scibot 30 Jul 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2018.08.015
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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sciencedirect.com/science/article/pii/S1535610818303751
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Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2019.08.051
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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1. scibot 27 Jul 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2018.08.015
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6179967/
Jun 2021
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MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway

1
1. scibot 24 Jun 2021
  
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  CVCL_0589
  
  DOI: 10.1016/j.ebiom.2021.103441
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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sciencedirect.com/science/article/pii/S2352396421002346
jitc.bmj.com jitc.bmj.com

T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia

1
1. scibot 12 Jun 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1136/jitc-2021-002509
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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jitc.bmj.com/content/9/5/e002509
May 2021
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A protocol for rapid degradation of endogenous transcription factors in mammalian cells and identification of direct regulatory targets

1
1. scibot 20 May 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.xpro.2021.100530
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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sciencedirect.com/science/article/pii/S2666166721002379
Apr 2021
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
1. scibot 24 Apr 2021
  
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  CRL-2724
  
  DOI: 10.1016/j.cell.2020.07.009
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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sciencedirect.com/science/article/pii/S0092867420308746
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Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1

1
1. scibot 21 Apr 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2021.109010
  
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sciencedirect.com/science/article/pii/S2211124721003247
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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

1
1. scibot 17 Apr 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2020.04.017
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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  RRID:CVCL_0589 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820302166
Mar 2021
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Tunable, division-independent control of gene activation timing by a polycomb switch

1
1. scibot 24 Mar 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2021.108888
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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sciencedirect.com/science/article/pii/S2211124721002023
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Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

1
1. scibot 02 Mar 2021
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.7554/eLife.65905
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:CVCL_0589
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ncbi.nlm.nih.gov/pmc/articles/PMC7886351/
Feb 2021
www.cell.com www.cell.com

Definition of a small core transcriptional circuit regulated by AML1-ETO

1
1. scibot 25 Feb 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.molcel.2020.12.005
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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  RRIDCUR:Validated RRID:CVCL_0589
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cell.com/molecular-cell/fulltext/S1097-2765(20)30897-2
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation

1
1. scibot 20 Jan 2021
  
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  RRID:CVCL_0589
  
  DOI: 10.1158/2643-3230.BCD-20-0155
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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  RRIDCUR:Validated RRID:CVCL_0589
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ncbi.nlm.nih.gov/pmc/articles/PMC7116590/
Oct 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

1
1. scibot 08 Oct 2020
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2020.108221
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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pubmed.ncbi.nlm.nih.gov/33027668/
Sep 2020
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RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

1
1. scibot 26 Sep 2020
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.stem.2020.04.009
  
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  RRIDCUR:Validated RRID:CVCL_0589
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sciencedirect.com/science/article/pii/S193459092030148X
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Prediction of Signed Protein Kinase Regulatory Circuits

1
1. scibot 25 Sep 2020
  
  in Public
  
  RRID:CVCL_0589
  
  DOI: 10.1016/j.cels.2020.04.005
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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  RRID:CVCL_0589 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2405471220301484
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-mediated Apoptosis.

1
1. scibot 16 Sep 2020
  
  in Public
  
  CVCL_0589
  
  DOI: 10.1158/1078-0432.CCR-19-1900
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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  RRIDCUR:Validated RRID:CVCL_0589
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clincancerres.aacrjournals.org/content/26/13/3371
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Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2

1
1. scibot 15 Sep 2020
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.cell.2020.03.051
  
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  RRID:CVCL_0589 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867420303445
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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

1
1. scibot 15 Sep 2020
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.celrep.2020.107840
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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  RRID:CVCL_0589 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720308214
www.cell.com www.cell.com

The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation

1
1. scibot 04 Sep 2020
  
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  RRID: CVCL_0589
  
  DOI: 10.1016/j.ccell.2018.08.015
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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cell.com/cancer-cell/fulltext/S1535-6108(18)30375-1
Jan 2020
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0589
  
  DOI: 10.1016/j.ccell.2019.04.006
  
  Resource: (BCRJ Cat# 0305, RRID:CVCL_0589)
  
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sciencedirect.com/science/article/pii/S1535610819302016
Nov 2018
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CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

1
1. scibot 05 Nov 2018
  
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  RRID:CVCL_0589
  
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  (ATCC Cat# CRL-2724, RRID:CVCL_0589)
  
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sciencedirect.com/science/article/pii/S1535610818302216

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