103 Matching Annotations
  1. Oct 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Olive Oil-Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12502211/
  3. www.sciencedirect.com www.sciencedirect.com
    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  4. Sep 2025
  5. 52.53.155.43 52.53.155.43
    2025.09.04.674332v2.full-html.html
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    52.53.155.43/304402c0b5b5e8844bb324b2732dfcb1e481f20c/2025.09.04.674332v2.full-html.html
  6. Jul 2025
  7. www.sciencedirect.com www.sciencedirect.com
    Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis
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    sciencedirect.com/science/article/pii/S2666379125003258
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Curcumin Induces Homologous Recombination Deficiency by BRCA2 Degradation in Breast Cancer and Normal Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12248657/
  9. Jun 2025
  10. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225011216-main-html.html
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    52.53.155.43/2abcfe5fe766e4300373f461f78d375160fe8922/1-s2.0-S2589004225011216-main-html.html
  11. May 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR Screening of Transcribed Super-Enhancers Identifies Drivers of Triple-Negative Breast Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534545/
  13. Apr 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11999952/
  15. Mar 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induction of Triple-Negative Breast Cancer Cell Death and Chemosensitivity Using mTORC2-Directed RNAi Nanomedicine
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    pmc.ncbi.nlm.nih.gov/articles/PMC11921867/
  17. Feb 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic Profiling of Breast Cancer Cell Lines: Unique and Shared Metabolites
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    pmc.ncbi.nlm.nih.gov/articles/PMC11816582/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to identify small-molecule inhibitors against cancer drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11821401/
  21. Jan 2025
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35271
  23. 52.53.155.43 52.53.155.43
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  24. Dec 2024
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC11621922/
  26. Nov 2024
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11575172/
  28. www.biorxiv.org www.biorxiv.org
    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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    biorxiv.org/content/10.1101/2024.11.07.622456v1
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  30. Sep 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
  32. www.sciencedirect.com www.sciencedirect.com
    Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124724011021
  33. www.sciencedirect.com www.sciencedirect.com
    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2451945624003234
  34. Aug 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetalax (Oxyphenisatin acetate, NSC 59687) and bisacodyl Cause Oncosis in Triple Negative Breast Cancer Cell lines by Poisoning Ion Exchange Membrane Protein TRPM4
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    ncbi.nlm.nih.gov/pmc/articles/PMC11322923/
  36. www.cell.com www.cell.com
    ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines
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    cell.com/cell-reports/fulltext/S2211-1247(24)00762-9
  37. aacrjournals.org aacrjournals.org
    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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    aacrjournals.org/cancerdiscovery/article/13/5/1210/726189/Targeted-MDM2-Degradation-Reveals-a-New
  38. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
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    embopress.org/doi/full/10.15252/emmm.202012716
  39. Jul 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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    sciencedirect.com/science/article/pii/S2589004224015013
  41. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  42. May 2024
  43. aacrjournals.org aacrjournals.org
    Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1
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    aacrjournals.org/clincancerres/article/30/7/1338/741831/Preclinical-Characterization-of-AZD9574-a-Blood
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078187/
  45. www.science.org www.science.org
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    science.org/doi/10.1126/sciadv.adj1468
  46. Apr 2024
  47. www.sciencedirect.com www.sciencedirect.com
    A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response
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    sciencedirect.com/science/article/pii/S2666379124001800
  48. www.sciencedirect.com www.sciencedirect.com
    Transcriptomics studies reveal functions of Transglutaminase 2 in breast cancer cells using membrane permeable and impermeable inhibitors
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    sciencedirect.com/science/article/pii/S0022283624001645
  49. Mar 2024
  50. www.sciencedirect.com www.sciencedirect.com
    Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides
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    sciencedirect.com/science/article/pii/S2211124724003127
  51. 52.53.155.43 52.53.155.43
    Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.
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  52. Feb 2024
  53. 52.53.155.43 52.53.155.43
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  55. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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    sciencedirect.com/science/article/pii/S0092867424000102
  56. Dec 2023
  57. www.sciencedirect.com www.sciencedirect.com
    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    sciencedirect.com/science/article/pii/S2666379123005438
  58. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
  59. Nov 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC1-C INTEGRATES AEROBIC GLYCOLYSIS WITH SUPPRESSION OF OXIDATIVE PHOSPHORYLATION IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10616323/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10618648/
  62. Oct 2023
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM21 mediates the synergistic effect of Olaparib and Sorafenib by degrading BRCA1 through ubiquitination in TNBC
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    ncbi.nlm.nih.gov/pmc/articles/PMC10589312/
  64. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
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    52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
  65. dx.doi.org dx.doi.org
    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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    dx.doi.org/10.1158/2767-9764.CRC-23-0236
  66. Sep 2023
  67. 52.53.155.43 52.53.155.43
    ALDH1A3 promotes invasion and metastasis in triple-negative breast cancer by regulating the plasminogen activation pathway
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    52.53.155.43/2f8328dc1dc33e6a3563ba1fede45bc3b7e7ee78/Molecular Oncology - 2023 - Bharadwaj-html.html
  68. Aug 2023
  69. 52.53.155.43 52.53.155.43
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  70. Jul 2023
  71. 52.53.155.43 52.53.155.43
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  72. Apr 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  74. Mar 2023
  75. academic.oup.com academic.oup.com
    Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad172/7079642
  76. Dec 2022
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  78. Jun 2022
  79. www.sciencedirect.com www.sciencedirect.com
    MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels
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    sciencedirect.com/science/article/pii/S2589004222007301
  80. www.sciencedirect.com www.sciencedirect.com
    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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    sciencedirect.com/science/article/pii/S2211124722006453
  81. May 2022
  82. www.sciencedirect.com www.sciencedirect.com
    Gold(III)-P-chirogenic complex induce mitochondrial dysfunction in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004222006113
  83. Mar 2022
  84. www.sciencedirect.com www.sciencedirect.com
    Proteome-centric cross-omics characterization and integrated network analyses of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124722001875
  85. www.sciencedirect.com www.sciencedirect.com
    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124722001759
  86. Feb 2022
  87. www.sciencedirect.com www.sciencedirect.com
    An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer
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    sciencedirect.com/science/article/pii/S2666379122000258
  88. Dec 2021
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An avian embryo patient-derived xenograft model for preclinical studies of human breast cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC8608609/
  90. Nov 2021
  91. www.sciencedirect.com www.sciencedirect.com
    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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    sciencedirect.com/science/article/pii/S1535610821006024
  92. www.sciencedirect.com www.sciencedirect.com
    A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors
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    sciencedirect.com/science/article/pii/S2211124721014303
  93. Sep 2021
  94. www.sciencedirect.com www.sciencedirect.com
    Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2451945621004001
  95. www.sciencedirect.com www.sciencedirect.com
    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
  96. Aug 2021
  97. jitc.bmj.com jitc.bmj.com
    Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids
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    jitc.bmj.com/content/9/8/e003000
  98. www.cell.com www.cell.com
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    cell.com/developmental-cell/abstract/S1534-5807(17)30871-7
  99. www.sciencedirect.com www.sciencedirect.com
    Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
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    sciencedirect.com/science/article/pii/S1097276517307141
  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The GEF‐H1/PKD3 signaling pathway promotes the maintenance of triple negative breast cancer stem cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32798
  101. www.sciencedirect.com www.sciencedirect.com
    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S2405471219303874
  102. Jul 2021
  103. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion
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    sciencedirect.com/science/article/pii/S1550413119300208
  104. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
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    sciencedirect.com/science/article/pii/S2211124719311520
  105. www.sciencedirect.com www.sciencedirect.com
    Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719307235
  106. www.sciencedirect.com www.sciencedirect.com
    Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
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    sciencedirect.com/science/article/pii/S2451945619301746
  107. www.sciencedirect.com www.sciencedirect.com
    Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719306953
  108. www.nature.com www.nature.com
    A chemical toolbox for the study of bromodomains and epigenetic signaling
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    nature.com/articles/s41467-019-09672-2
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5726799/
  110. May 2021
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limited inhibition of multiple nodes in a driver network blocks metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8128439/
  112. www.sciencedirect.com www.sciencedirect.com
    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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    sciencedirect.com/science/article/pii/S1097276520305815
  113. www.sciencedirect.com www.sciencedirect.com
    Deciphering the signaling network of breast cancer improves drug sensitivity prediction
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    sciencedirect.com/science/article/pii/S2405471221001113
  114. Apr 2021
  115. www.sciencedirect.com www.sciencedirect.com
    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    sciencedirect.com/science/article/pii/S1550413120305453
  116. Mar 2021
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intein-mediated cytoplasmic reconstitution of a split toxin enables selective cell ablation in mixed populations and tumor xenografts
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    ncbi.nlm.nih.gov/pmc/articles/PMC7486740/
  118. Feb 2021
  119. www.sciencedirect.com www.sciencedirect.com
    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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    sciencedirect.com/science/article/pii/S2211124721000577
  120. Nov 2020
  121. www.sciencedirect.com www.sciencedirect.com
    G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
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    sciencedirect.com/science/article/pii/S2211124720313309
  122. Oct 2020
  123. www.cell.com www.cell.com
    Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing
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    cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
  124. mcr.aacrjournals.org mcr.aacrjournals.org
    Elevated V-ATPase activity following PTEN loss is required for enhanced oncogenic signaling in breast cancer
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    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
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  130. Jan 2020
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    Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis
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    miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
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    VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells
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    Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21
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    Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion
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  137. Nov 2018
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    CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress
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    DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4
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    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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  145. Nov 2017
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