110 Matching Annotations
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    STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2211124725012008
  3. Oct 2025
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    Intestinal Lachnospiraceae bacterium-derived propionate inhibits the progression of clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379125004835
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    ROR2-specific CAR T cells are effective against hematologic and solid tumors and well tolerated in mice
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    sciencedirect.com/science/article/pii/S2666379125004732
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated single-cell and bulk transcriptome analysis revealed high plasticity subpopulation and promising diagnosis model for clear cell renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12487111/
  7. Sep 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11913570/
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    ARID1A stabilizes non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin
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    sciencedirect.com/science/article/pii/S2211124725010484
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    Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling
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    biorxiv.org/content/10.1101/2025.08.31.673338v1
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    Targeting FSP1 to induce ferroptosis in chromophobe renal cell carcinoma
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    nature.com/articles/s41388-025-03562-2
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proteogenomic Analysis Identifies Clinically Relevant Subgroups of Collecting Duct Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12408255/
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    Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12366518/
  14. Aug 2025
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    Multimodal targeting of metastatic renal cell carcinoma via CD70-directed allogeneic CAR-NKT cells
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    sciencedirect.com/science/article/pii/S2666379125003945
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    Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma
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    TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation
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    sciencedirect.com/science/article/pii/S221112472500957X
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    Design of multi-target peptide modulators for protein chaperone networks
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    sciencedirect.com/science/article/pii/S0969212625002692
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differential Efficacy of Bevacizumab and Erlotinib in Preclinical Models of Renal Medullary Carcinoma and Fumarate Hydratase–Deficient Renal Cell Carcinoma
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    The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi
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    sciencedirect.com/science/article/pii/S1534580725004484
  21. Jul 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Long-term administration of hydrogen-rich water enhances quality of life in diabetic rats and reduces renal neoplasm incidence through modulation of inflammatory and metabolic pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12271932/
  23. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
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    Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12265667/
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    Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
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  26. Jun 2025
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    PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma
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    nature.com/articles/s41419-025-07782-y
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    Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12161473/
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    Membrane-bound IL-15 co-expression powers a potent and persistent CD70-targeted TRuC T-cell therapy
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    Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket
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    sciencedirect.com/science/article/pii/S258900422400124X
  31. May 2025
  32. 52.53.155.43 52.53.155.43
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    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079101/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ankrd1 Promotes Lamellipodia Formation and Cell Motility via Interaction with Talin-1 in Clear Cell Renal Cell Carcinoma
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  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Avelumab induces greater Fc-Fc receptor-dependent natural killer cell activation and dendritic cell crosstalk compared to durvalumab
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  37. Apr 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of SETD2 in wild‐type VHL clear cell renal cell carcinoma sensitizes cells to STF‐62247 and leads to DNA damage, cell cycle arrest, and cell death characteristic of pyroptosis
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    An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation
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    Versatile roles of annexin A4 in clear cell renal cell carcinoma: Impact on membrane repair, transcriptional signatures, and composition of the tumor microenvironment
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  41. Mar 2025
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    HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy
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  44. Feb 2025
  45. aacrjournals.org aacrjournals.org
    Hypertension promotes the proliferation and migration of ccRCC cells by downregulation of TIMP3 in tumor endothelial cells through the miR-21-5p/TGFBR2/P38/EGR1 axis
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    Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11803400/
  47. Jan 2025
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression
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    Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1
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    Integrated machine learning reveals the role of tryptophan metabolism in clear cell renal cell carcinoma and its association with patient prognosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11662763/
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    Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers
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  52. Dec 2024
  53. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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  54. Nov 2024
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    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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    sciencedirect.com/science/article/pii/S107476132400493X
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    PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
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    Machine learning-derived natural killer cell signature predicts prognosis and therapeutic response in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S1936523324003061
  58. Sep 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identify BCAT1 plays an oncogenic role and promotes EMT in KIRC via single cell RNA-seq and experiment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11422235/
  60. Aug 2024
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    A genetic basis for sex differences in Xp11 translocation renal cell carcinoma
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  63. Jul 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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    CXCL3/TGF-β-Mediated Crosstalk Between CAFs and Tumor Cells Augments RCC Progression and Sunitinib Resistance
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  66. Jun 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma
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    De novo and salvage purine synthesis pathways across tissues and tumors
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  69. May 2024
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    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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    Radix Actinidiae chinensis induces the autophagy and apoptosis in renal cell carcinoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11103827/
  72. aacrjournals.org aacrjournals.org
    Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
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    aacrjournals.org/cancerres/article/84/10/1570/745316/Bile-Acid-Metabolism-Mediates-Cholesterol
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 Deficiency Confers Sensitivity to Dual Inhibition of DNA Methylation and PARP in Kidney Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10843145/
  74. Apr 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  76. Mar 2024
  77. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy
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  78. www.mdpi.com www.mdpi.com
    A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells
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    A gut-derived hormone regulates cholesterol metabolism
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  80. Jan 2024
  81. transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com
    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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    transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
  82. Dec 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10690095/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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    Silver Nanoparticles (AgNPs) as Enhancers of Everolimus and Radiotherapy Sensitivity on Clear Cell Renal Cell Carcinoma
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    mdpi.com/2076-3921/12/12/2051
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10646479/
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    circWSB1 promotes tumor progression in ccRCC via circWSB1/miR-182-5p/WSB1 axis
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  88. Oct 2023
  89. www.sciencedirect.com www.sciencedirect.com
    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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    MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
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  92. Aug 2023
  93. www.sciencedirect.com www.sciencedirect.com
    An oncogenic isoform of septin 9 promotes the formation of juxtanuclear invadopodia by reducing nuclear deformability
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  94. Jul 2023
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    FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteogenomics of clear cell renal cell carcinoma response to tyrosine kinase inhibitor
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  98. Jun 2023
  99. www.nature.com www.nature.com
    piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination
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    nature.com/articles/s12276-023-01010-3
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    Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34575
  101. May 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9633392/
  103. Apr 2023
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular vesicles secreted from bone metastatic renal cell carcinoma promote angiogenesis and endothelial gap formation in bone marrow in a time-dependent manner in a preclinical mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10091619/
  105. Mar 2023
  106. www.sciencedirect.com www.sciencedirect.com
    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    sciencedirect.com/science/article/pii/S0021925823002636
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative Single-Cell Analysis Reveals Transcriptional and Epigenetic Regulatory Features of Clear Cell Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9978887/
  108. Feb 2023
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress‐related tumorigenicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9899607/
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Vesicle-Mediated Transfer of LncRNA IGFL2-AS1 Confers Sunitinib Resistance in Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9811158/
  111. Jan 2023
  112. www.sciencedirect.com www.sciencedirect.com
    RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer
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    sciencedirect.com/science/article/pii/S221112472300027X
  113. Dec 2022
  114. www.sciencedirect.com www.sciencedirect.com
    Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness
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  118. Aug 2022
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  125. May 2022
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