99 Matching Annotations
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    Multimodal targeting of metastatic renal cell carcinoma via CD70-directed allogeneic CAR-NKT cells
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    sciencedirect.com/science/article/pii/S2666379125003945
  3. Aug 2025
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    Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma
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    TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation
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    Design of multi-target peptide modulators for protein chaperone networks
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    sciencedirect.com/science/article/pii/S0969212625002692
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    Differential Efficacy of Bevacizumab and Erlotinib in Preclinical Models of Renal Medullary Carcinoma and Fumarate Hydratase–Deficient Renal Cell Carcinoma
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    The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi
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  9. Jul 2025
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    Long-term administration of hydrogen-rich water enhances quality of life in diabetic rats and reduces renal neoplasm incidence through modulation of inflammatory and metabolic pathways
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    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
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    Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
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  14. Jun 2025
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    PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma
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    Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1
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    Membrane-bound IL-15 co-expression powers a potent and persistent CD70-targeted TRuC T-cell therapy
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    Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket
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  19. May 2025
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    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma
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    Ankrd1 Promotes Lamellipodia Formation and Cell Motility via Interaction with Talin-1 in Clear Cell Renal Cell Carcinoma
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    Avelumab induces greater Fc-Fc receptor-dependent natural killer cell activation and dendritic cell crosstalk compared to durvalumab
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  25. Apr 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of SETD2 in wild‐type VHL clear cell renal cell carcinoma sensitizes cells to STF‐62247 and leads to DNA damage, cell cycle arrest, and cell death characteristic of pyroptosis
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    An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation
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    Versatile roles of annexin A4 in clear cell renal cell carcinoma: Impact on membrane repair, transcriptional signatures, and composition of the tumor microenvironment
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  29. Mar 2025
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  32. Feb 2025
  33. aacrjournals.org aacrjournals.org
    Hypertension promotes the proliferation and migration of ccRCC cells by downregulation of TIMP3 in tumor endothelial cells through the miR-21-5p/TGFBR2/P38/EGR1 axis
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    Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma
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  35. Jan 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression
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    Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1
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    Integrated machine learning reveals the role of tryptophan metabolism in clear cell renal cell carcinoma and its association with patient prognosis
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    Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers
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  40. Dec 2024
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    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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  42. Nov 2024
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    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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  46. Sep 2024
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    Identify BCAT1 plays an oncogenic role and promotes EMT in KIRC via single cell RNA-seq and experiment
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  48. Aug 2024
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    A genetic basis for sex differences in Xp11 translocation renal cell carcinoma
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  51. Jul 2024
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    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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  54. Jun 2024
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  57. May 2024
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    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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    Radix Actinidiae chinensis induces the autophagy and apoptosis in renal cell carcinoma cells
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    Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
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    SETD2 Deficiency Confers Sensitivity to Dual Inhibition of DNA Methylation and PARP in Kidney Cancer
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  62. Apr 2024
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    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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  64. Mar 2024
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    Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy
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    A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells
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  68. Jan 2024
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    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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  70. Dec 2023
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    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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    Silver Nanoparticles (AgNPs) as Enhancers of Everolimus and Radiotherapy Sensitivity on Clear Cell Renal Cell Carcinoma
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  76. Oct 2023
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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  80. Aug 2023
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    An oncogenic isoform of septin 9 promotes the formation of juxtanuclear invadopodia by reducing nuclear deformability
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  82. Jul 2023
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    FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy
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    Proteogenomics of clear cell renal cell carcinoma response to tyrosine kinase inhibitor
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  86. Jun 2023
  87. www.nature.com www.nature.com
    piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination
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    Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition
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  89. May 2023
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
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  91. Apr 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular vesicles secreted from bone metastatic renal cell carcinoma promote angiogenesis and endothelial gap formation in bone marrow in a time-dependent manner in a preclinical mouse model
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  93. Mar 2023
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    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    Integrative Single-Cell Analysis Reveals Transcriptional and Epigenetic Regulatory Features of Clear Cell Renal Cell Carcinoma
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  96. Feb 2023
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress‐related tumorigenicity
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    Extracellular Vesicle-Mediated Transfer of LncRNA IGFL2-AS1 Confers Sunitinib Resistance in Renal Cell Carcinoma
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  99. Jan 2023
  100. www.sciencedirect.com www.sciencedirect.com
    RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer
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  101. Dec 2022
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    Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness
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  104. Oct 2022
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    Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors
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  106. Aug 2022
  107. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma
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    jeccr.biomedcentral.com/articles/10.1186/s13046-022-02467-2
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    Systematic study of tissue factor expression in solid tumors
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  109. Jul 2022
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    Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy
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  111. Jun 2022
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    An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma
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  113. May 2022
  114. link.springer.com link.springer.com
    N6-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma
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  115. Apr 2022
  116. www.nature.com www.nature.com
    A proteogenomic analysis of clear cell renal cell carcinoma in a Chinese population
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    An in vivo orthotopic serial passaging model for a metastatic renal cancer study
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  119. Mar 2022
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    Stratifying ferroptosis sensitivity in cells and mouse tissues by photochemical activation of lipid peroxidation and fluorescent imaging
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    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
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  122. Dec 2021
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    Upregulation of homeobox D10 expression suppresses invasion and migration of clear cell renal cell carcinoma through targeting of E-cadherin
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  125. Nov 2021
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    PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ
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  127. Oct 2021
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    Therapeutic potential of Smilax fluminensis ethanolic extract: antitumoral activity in murine melanoma cells
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  129. Sep 2021
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes
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  132. Jul 2021
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    ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors
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  134. May 2021
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  136. Mar 2021
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  138. Sep 2020
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    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
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  141. Jan 2020
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