109 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA sequencing–based evaluation of the mechanisms underlying the liensinine-mediated inhibition of hypopharyngeal cancer proliferation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12914065/
  3. Feb 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trim15 stabilizes VDAC3 via ubiquitination to suppress autophagy and enhance chemosensitivity in hypopharyngeal squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12876940/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aberrant Hippo-YAP/TEAD Signaling Drives Malignant Transcriptional Reprogramming in External Auditory Canal Squamous Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12862246/
  6. Jan 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T2R5 agonist phendione decreases cell viability and induces apoptosis in head and neck squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12818364/
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    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    sciencedirect.com/science/article/pii/S2211124725016547
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    KLF7 promotes progression of Head and Neck Squamous Cell Carcinoma by remodeling tumor immune microenvironment
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    sciencedirect.com/science/article/pii/S0304383525008092
  10. Dec 2025
  11. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD-L1 Expression and Acts as a Target to Enhance Anti-PD-1 Efficacy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202514347
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human papillomavirus-related oropharyngeal squamous cell carcinoma exhibits enhanced radiosensitivity despite limited activation of cytosolic DNA sensing pathways and innate immune responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12707452/
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    HOMER3 drives oral squamous cell carcinoma progression through TRPV6 calcium influx and TUBB3 microtubule stabilization
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    nature.com/articles/s41388-025-03611-w
  14. Nov 2025
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    A moonlighting function of tumoral interleukin-1β precursor promotes metastasis via RACK1-mediated actin remodeling
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    nature.com/articles/s41467-025-65220-1
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    Therapeutic stress triggers tumor STAT1 acetylation to disarm immunotherapy
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    sciencedirect.com/science/article/pii/S266637912500521X
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    Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells
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    sciencedirect.com/science/article/pii/S2666379125005191
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quercetin as a Bitter Taste Receptor Agonist with Anticancer Effects in Head and Neck Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12567344/
  19. Oct 2025
  20. www.biorxiv.org www.biorxiv.org
    Lipid nanoparticle co-delivery of mRNA and a small molecule drug for oral cancer chemoimmunotherapy
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    biorxiv.org/content/10.1101/2025.09.26.678832v1
  21. Sep 2025
  22. www.nature.com www.nature.com
    The antitumor effect of tlr4 inhibition in head and neck cancer cell lines
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    nature.com/articles/s41598-025-15927-4
  23. Jun 2025
  24. www.tandfonline.com www.tandfonline.com
    TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts
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    tandfonline.com/doi/full/10.1080/15548627.2025.2508064
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the Glucose–Insulin Link in Head and Neck Squamous Cell Carcinoma Induces Cytotoxic Oxidative Stress and Inhibits Cancer Growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12141995/
  26. May 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Avelumab induces greater Fc-Fc receptor-dependent natural killer cell activation and dendritic cell crosstalk compared to durvalumab
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    pmc.ncbi.nlm.nih.gov/articles/PMC12051578/
  28. Apr 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ultrasensitive Detection and Monitoring of Circulating Tumor DNA Using Structural Variants in Early-Stage Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11994999/
  30. www.nature.com www.nature.com
    Tumor cells that resist neutrophil anticancer cytotoxicity acquire a prometastatic and innate immune escape phenotype
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    nature.com/articles/s41423-025-01283-w
  31. Mar 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multi-omics analysis identifies a liquid-liquid phase separation-related subtypes in head and neck squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11897011/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical investigation of anti-tumor efficacy of allogeneic natural killer cells combined with cetuximab for head and neck squamous cell carcinoma
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  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11834217/
  35. Feb 2025
  36. www.sciencedirect.com www.sciencedirect.com
    KGF impedes TRIM21-enhanced stabilization of keratin 10 mediating differentiation in hypopharyngeal cancer
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  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAC1-Amplified and RAC1-A159V Hotspot-Mutated Head and Neck Cancer Sensitive to the Rac Inhibitor EHop-016 In Vivo: A Proof-of-Concept Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC11816149/
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    PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma
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  39. Jan 2025
  40. www.nature.com www.nature.com
    Molecular correlates for HPV-negative head and neck cancer engraftment prognosticate patient outcomes
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    nature.com/articles/s41467-024-55203-z
  41. Dec 2024
  42. 52.53.155.43 52.53.155.43
    ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway-html.html
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    Transcriptome Analysis of HNSCC by Aggregatibacter actinomycetemcomitans Extracellular Vesicles
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    onlinelibrary.wiley.com/doi/full/10.1111/odi.15204
  44. Oct 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984770/
  46. Aug 2024
  47. search.proquest.com search.proquest.com
    Cancer-Associated Fibroblast Subgroups Showing Differential Promoting Effect on HNSCC Progression - ProQuest
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  48. Jul 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immunomodulatory ballet of tumour‐derived extracellular vesicles and neutrophils orchestrating the dynamic CD73/PD‐L1 pathway in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11231043/
  50. Jun 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC11210931/
  52. May 2024
  53. 52.53.155.43 52.53.155.43
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  54. Mar 2024
  55. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
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    Interplay of p62-mTORC1 and EGFR signaling promotes cisplatin resistance in oral cancer
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    DDX3 regulates cancer immune surveillance via 3′ UTR-mediated cell-surface expression of PD-L1
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    sciencedirect.com/science/article/pii/S2211124724002651
  58. 52.53.155.43 52.53.155.43
    TMEM16A inhibits autophagy and promotes the invasion of hypopharyngeal squamous cell carcinoma through mTOR pathway
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  59. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13620
  60. Feb 2024
  61. aacrjournals.org aacrjournals.org
    An antibody-drug conjugate directed to tissue factor shows preclinical anti-tumor activity in head and neck cancer as a single agent and in combination with chemoradiotherapy
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    aacrjournals.org/mct/article/23/2/187/733943/An-Antibody-Drug-Conjugate-Directed-to-Tissue
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    Dual anti-HER2/EGFR inhibition synergistically increases therapeutic effects and alters tumor oxygenation in HNSCC
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    ncbi.nlm.nih.gov/pmc/articles/PMC10866896/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10850803/
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Survivin/BIRC5 as a novel molecular effector at the crossroads of glucose metabolism and radioresistance in head and neck squamous cell carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/hed.27651
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ORAOV1, CCND1, and MIR548K Are the Driver Oncogenes of the 11q13 Amplicon in Squamous Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831340/
  66. Jan 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10793589/
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    KH-like domains in PARP9/DTX3L and PARP14 coordinate protein-protein interactions to promote cancer cell survival
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    sciencedirect.com/science/article/pii/S002228362300551X
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential effect of cancer-associated fibroblast-derived extracellular vesicles on cisplatin resistance in oral squamous cell carcinoma via miR-876-3p
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    ncbi.nlm.nih.gov/pmc/articles/PMC10758057/
  70. Dec 2023
  71. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13567
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Revisiting the role of endogenous STAT3 in HPV-positive cervical cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/jmv.29230
  73. 52.53.155.43 52.53.155.43
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  74. Nov 2023
  75. link.springer.com link.springer.com
    ESCO2 promotes hypopharyngeal carcinoma progression in a STAT1-dependent manner
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  76. Oct 2023
  77. www.sciencedirect.com www.sciencedirect.com
    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fusobacterium nucleatum facilitates proliferation and autophagy by activating miR-361-3p/NUDT1 axis through oxidative stress in hypopharyngeal squamous cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10580517/
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    Cancer Medicine - 2023 - Kamer - Evaluation of the effect of intensity‐modulated radiotherapy IMRT and-html.html
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    52.53.155.43/cbf670ef8096a17c56cc70505c6f3539b18ca3de/Cancer Medicine - 2023 - Kamer - Evaluation of the effect of intensity-modulated radiotherapy IMRT and-html.html
  80. Sep 2023
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
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    ncbi.nlm.nih.gov/pmc/articles/PMC10473160/
  82. Aug 2023
  83. link.springer.com link.springer.com
    Tumoral P2Y2 receptor modulates tumor growth and host anti-tumor immune responses in a syngeneic murine model of oral cancer
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    link.springer.com/article/10.1007/s11302-023-09960-z
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    Activation of the EGFR/PI3K/AKT pathway limits the efficacy of trametinib treatment in head and neck cancer
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    52.53.155.43/a89642d6f87c2ead71e5c2fab9e6c6878c0c2d54/Molecular Oncology - 2023 - Novoplansky - Activation of the EGFR PI3K AKT pathway limits the efficacy of trametinib-html.html
  85. Jul 2023
  86. www.sciencedirect.com www.sciencedirect.com
    Cancer-keeper genes as therapeutic targets
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    sciencedirect.com/science/article/pii/S2589004223013731
  87. www.sciencedirect.com www.sciencedirect.com
    Co-targeting autophagy and NRF2 signaling triggers mitochondrial superoxide to sensitize oral cancer stem cells for cisplatin-induced apoptosis
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    sciencedirect.com/science/article/pii/S0891584923005269
  88. clinicalepigeneticsjournal.biomedcentral.com clinicalepigeneticsjournal.biomedcentral.com
    CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma
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    clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-023-01525-6
  89. May 2023
  90. www.mdpi.com www.mdpi.com
    Cancer-Associated Fibroblast Subgroups Showing Differential Promoting Effect on HNSCC Progression
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    mdpi.com/2072-6694/13/4/654/htm
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circFNDC3B Accelerates Vasculature Formation and Metastasis in Oral Squamous Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152237/
  92. Apr 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fanconi anemia-isogenic head and neck cancer cell line pairs - a basic and translational science resource
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34506
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP9X expression is functionally related to laryngeal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10088544/
  96. Mar 2023
  97. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
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    europepmc.org/article/med/36952341
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pixelated Microfluidics for Drug Screening on Tumour Spheroids and Ex Vivo Microdissected Tumour Explants
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    ncbi.nlm.nih.gov/pmc/articles/PMC9954565/
  99. Feb 2023
  100. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    HSF1 activates the FOXO3a–ΔNp63α–CDK4 axis to promote head and neck squamous cell carcinoma cell proliferation and tumor growth
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14588
  101. www.tandfonline.com www.tandfonline.com
    CLU (clusterin) promotes mitophagic degradation of MSX2 through an AKT-DNM1L/Drp1 axis to maintain SOX2-mediated stemness in oral cancer stem cells
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    tandfonline.com/doi/abs/10.1080/15548627.2023.2178876
  102. Dec 2022
  103. www.sciencedirect.com www.sciencedirect.com
    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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    sciencedirect.com/science/article/pii/S2211124722016527
  104. Oct 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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    sciencedirect.com/science/article/pii/S1097276522008966
  106. May 2022
  107. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel fluorescent GLUT1 inhibitor for precision detection and fluorescence image-guided surgery in oral squamous cell carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34049
  108. bmcmedicine.biomedcentral.com bmcmedicine.biomedcentral.com
    Palbociclib-based high-throughput combination drug screening identifies synergistic therapeutic options in HPV-negative head and neck squamous cell carcinoma
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    bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02373-6
  109. www.mdpi.com www.mdpi.com
    mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells
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    mdpi.com/2072-6694/14/9/2286
  110. Feb 2022
  111. www.sciencedirect.com www.sciencedirect.com
    Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
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    sciencedirect.com/science/article/pii/S2211124722001462
  112. Nov 2021
  113. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    HPV Sequencing Facilitates Ultrasensitive Detection of HPV Circulating Tumor DNA
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    clincancerres.aacrjournals.org/content/27/21/5857
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pre-screening strategy to assess resected tumor margins by imaging cytoplasmic viscosity and hypoxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8553343/
  115. Oct 2021
  116. www.sciencedirect.com www.sciencedirect.com
    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S1097276521008340
  117. Sep 2021
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8449240/
  119. Aug 2021
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Angiogenic Potential of 3-Dimension Spheroid of HNSCC Cells in Mouse Xenograft
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